A subject this map covers
Immunomodulatory drugs
Part of: Inflammation and immune response
What belongs here
Drugs that change the immune response after injury, other than steroids and minocycline, which have their own concepts.
What does not belong here, however close it looks
Immunosuppression to keep a graft alive is part of cell therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 678 records · 1968–2026
- Indexed as work in animals: 932 records · 1982–2026
- Indexed as laboratory work: 34 records · 1991–2026
- The source has not said who or what was studied: 437 records · 1977–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
2081 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- HSP70 alleviates spinal cord injury by activating the NF-kB pathway. — PubMed · 2021 · Journal Article
- Inhibition of Dectin-1 Ameliorates Neuroinflammation by Regulating Microglia/Macrophage Phenotype After Intracerebral Hemorrhage in Mice. — PubMed · 2021 · Journal Article
- Silencing of miR-324-5p alleviates rat spinal cord injury by Sirt1. — PubMed · 2021 · Journal Article
- Synergistic neuroprotective effects of hyperbaric oxygen and N-acetylcysteine against traumatic spinal cord injury in rat. — PubMed · 2021 · Journal Article
- The role and transformative potential of IL-19 in atherosclerosis. — PubMed · 2021 · Journal Article
- Optimizing fibrin hydrogel toward effective neural progenitor cell delivery in spinal cord injury. — PubMed · 2021 · Journal Article
- Engineered extracellular vesicles derived from primary M2 macrophages with anti-inflammatory and neuroprotective properties for the treatment of spinal cord injury. — PubMed · 2021 · Journal Article
- Geniposide exerts protective effects on spinal cord injury in rats by inhibiting the IKKs/NF-κB signaling pathway. — PubMed · 2021 · Journal Article
- Polydopamine-Decorated Microcomposites Promote Functional Recovery of an Injured Spinal Cord by Inhibiting Neuroinflammation. — PubMed · 2021 · Journal Article
- Interleukin-4 and interleukin-13 induce different metabolic profiles in microglia and macrophages that relate with divergent outcomes after spinal cord injury. — PubMed · 2021 · Journal Article
- Ameliorative effects of miR-423-5p against polarization of microglial cells of the M1 phenotype by targeting a NLRP3 inflammasome signaling pathway. — PubMed · 2021 · Journal Article
- Dapsone Prevents Allodynia and Hyperalgesia and Decreased Oxidative Stress After Spinal Cord Injury in Rats. — PubMed · 2021 · Journal Article
- Rat Bone Mesenchymal Stem Cell-Derived Exosomes Loaded with miR-494 Promoting Neurofilament Regeneration and Behavioral Function Recovery after Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Resveratrol inhibits inflammation after spinal cord injury via SIRT-1/NF-κB signaling pathway. — PubMed · 2021 · Journal Article
- Thermosensitive collagen/fibrinogen gels loaded with decorin suppress lesion site cavitation and promote functional recovery after spinal cord injury. — PubMed · 2021 · Journal Article
- Cervical spinal cord injury-induced neuropathic pain in male mice is associated with a persistent pro-inflammatory macrophage/microglial response in the superficial dorsal horn. — PubMed · 2021 · Journal Article
- Effect of electroacupuncture on inhibition of inflammatory response and oxidative stress through activating ApoE and Nrf2 in a mouse model of spinal cord injury. — PubMed · 2021 · Journal Article
- MicroRNA-182 improves spinal cord injury in mice by modulating apoptosis and the inflammatory response via IKKβ/NF-κB. — PubMed · 2021 · Journal Article
- [Necrostatin-1 promotes locomotor recovery after spinal cord injury through inhibiting apoptosis and M1 polarization of microglia/macrophage in mice]. — PubMed · 2021 · Journal Article
- Sesamol-loaded stearic acid-chitosan nanomicelles mitigate the oxidative stress-stimulated apoptosis and induction of pro-inflammatory cytokines in motor neuronal of the spinal cord through NF-ĸB signaling pathway. — PubMed · 2021 · Journal Article
- The protective effect of betanin and copper on spinal cord ischemia-reperfusion injury. — PubMed · 2021 · Journal Article
- Keratin Biomaterials Improve Functional Recovery in a Rat Spinal Cord Injury Model. — PubMed · 2021 · Journal Article
- A 3D Fiber-Hydrogel Based Non-Viral Gene Delivery Platform Reveals that microRNAs Promote Axon Regeneration and Enhance Functional Recovery Following Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Activation of Neuroprotective Microglia and Astrocytes at the Lesion Site and in the Adjacent Segments Is Crucial for Spontaneous Locomotor Recovery after Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Spontaneous apoptosis of cells in therapeutic stem cell preparation exert immunomodulatory effects through release of phosphatidylserine. — PubMed · 2021 · Journal Article
- TAT-modified tetramethylpyrazine-loaded nanoparticles for targeted treatment of spinal cord injury. — PubMed · 2021 · Journal Article
- Histopathological Evaluation of Spinal Cord with Experimental Traumatic Injury Following Implantation of a Controlled Released Drug Delivery System of Chitosan Hydrogel Loaded with Selenium Nanoparticle. — PubMed · 2021 · Journal Article
- IL-10 lentivirus-laden hydrogel tubes increase spinal progenitor survival and neuronal differentiation after spinal cord injury. — PubMed · 2021 · Journal Article
- Proteomics and bioinformatics reveal insights into neuroinflammation in the acute to subacute phases in rat models of spinal cord contusion injury. — PubMed · 2021 · Journal Article
- Beyond the lesion site: minocycline augments inflammation and anxiety-like behavior following SCI in rats through action on the gut microbiota. — PubMed · 2021 · Journal Article
- SiRNA in MSC-derived exosomes silences CTGF gene for locomotor recovery in spinal cord injury rats. — PubMed · 2021 · Journal Article
- Cystine-glutamate antiporter deletion accelerates motor recovery and improves histological outcomes following spinal cord injury in mice. — PubMed · 2021 · Journal Article
- Diagnosis and treatment of epidural empyema in a pygmy goat. — PubMed · 2021 · Case Reports
- Effects of Ganoderma lucidum Polysaccharides on Different Pathways Involved in the Development of Spinal Cord Ischemia Reperfusion Injury: Biochemical, Histopathologic, and Ultrastructural Analysis in a Rat Model. — PubMed · 2021 · Journal Article
- LncRNA CASC9 attenuates lactate dehydrogenase-mediated oxidative stress and inflammation in spinal cord injury via sponging miR-383-5p. — PubMed · 2021 · Journal Article
- Sonic Hedgehog modulates the inflammatory response and improves functional recovery after spinal cord injury in a thoracic contusion-compression model. — PubMed · 2021 · Journal Article
- Programmed death protein 1 is essential for maintaining the anti-inflammatory function of infiltrating regulatory T cells in a murine spinal cord injury model. — PubMed · 2021 · Journal Article
- Berberine-loaded M2 macrophage-derived exosomes for spinal cord injury therapy. — PubMed · 2021 · Journal Article
- Lithium alleviated spinal cord injury (SCI)-induced apoptosis and inflammation in rats via BDNF-AS/miR-9-5p axis. — PubMed · 2021 · Journal Article
- Verbascoside Attenuates Acute Inflammatory Injury Caused by an Intracerebral Hemorrhage Through the Suppression of NLRP3. — PubMed · 2021 · Journal Article
- Peripheral Macrophage-derived Exosomes promote repair after Spinal Cord Injury by inducing Local Anti-inflammatory type Microglial Polarization via Increasing Autophagy. — PubMed · 2021 · Journal Article
- Presence and activation of pro-inflammatory macrophages are associated with CRYAB expression in vitro and after peripheral nerve injury. — PubMed · 2021 · Journal Article
- Isorhamnetin promotes functional recovery in rats with spinal cord injury by abating oxidative stress and modulating M2 macrophages/microglia polarization. — PubMed · 2021 · Journal Article
- Betulinic acid inhibits pyroptosis in spinal cord injury by augmenting autophagy via the AMPK-mTOR-TFEB signaling pathway. — PubMed · 2021 · Journal Article
- Luteolin Modulates the NF-E2-Related Factor 2/Glutamate-Cysteine Ligase Pathway in Rats with Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Mitigation of Microglia-mediated Acute Neuroinflammation and Tissue Damage by Heme Oxygenase 1 in a Rat Spinal Cord Injury Model. — PubMed · 2021 · Journal Article
- Neuroprotective Effects of Milrinone on Experimental Acute Spinal Cord Injury: Rat Model. — PubMed · 2021 · Journal Article
- Cardiometabolic risks and atherosclerotic disease in ApoE knockout mice: Effect of spinal cord injury and Salsalate anti-inflammatory pharmacotherapy. — PubMed · 2021 · Journal Article
- Machine intelligence identifies soluble TNFa as a therapeutic target for spinal cord injury. — PubMed · 2021 · Journal Article
- Nanoparticle-Based Estrogen Delivery to Spinal Cord Injury Site Reduces Local Parenchymal Destruction and Improves Functional Recovery. — PubMed · 2021 · Journal Article
- Spinal cord injury alters microRNA and CD81+ exosome levels in plasma extracellular nanoparticles with neuroinflammatory potential. — PubMed · 2021 · Journal Article
- Delayed administration of high dose human immunoglobulin G enhances recovery after traumatic cervical spinal cord injury by modulation of neuroinflammation and protection of the blood spinal cord barrier. — PubMed · 2021 · Journal Article
- Dexmedetomidine Reduces the Lidocaine-Induced Neurotoxicity by Inhibiting Inflammasome Activation and Reducing Pyroptosis in Rats. — PubMed · 2021 · Journal Article
- Extracellular and nuclear roles of IL-37 after spinal cord injury. — PubMed · 2021 · Journal Article
- Imaging of Neurotrauma in Acute and Chronic Settings. — PubMed · 2021 · Journal Article
- Lentiviral Interleukin-10 Gene Therapy Preserves Fine Motor Circuitry and Function After a Cervical Spinal Cord Injury in Male and Female Mice. — PubMed · 2021 · Journal Article
- Neonatal Rats Exhibit a Predominantly Anti-Inflammatory Response following Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Neurologic and Histologic Tests Used to Measure Neuroprotective Effectiveness of Virus-Derived Immune-Modulating Proteins. — PubMed · 2021 · Journal Article
- Polyphenols as Potential Therapeutics for Pain and Inflammation in Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Resolvin D3 Promotes Inflammatory Resolution, Neuroprotection, and Functional Recovery After Spinal Cord Injury. — PubMed · 2021 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 13 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1741999 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 17 · this programme has 2063 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("immunomodulation" OR "anti-inflammatory") - Crossref
spinal cord injury immunomodulation anti-inflammatory - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Immunomodulating Agents"[MeSH Terms] OR "Anti-Inflammatory Agents"[MeSH Terms] OR "immunomodulation"[Title/Abstract] OR "anti-inflammatory"[Title/Abstract])