A subject this map covers
Immunomodulatory drugs
Part of: Inflammation and immune response
What belongs here
Drugs that change the immune response after injury, other than steroids and minocycline, which have their own concepts.
What does not belong here, however close it looks
Immunosuppression to keep a graft alive is part of cell therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 678 records · 1968–2026
- Indexed as work in animals: 932 records · 1982–2026
- Indexed as laboratory work: 34 records · 1991–2026
- The source has not said who or what was studied: 437 records · 1977–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
2081 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Sumatriptan improves the locomotor activity and neuropathic pain by modulating neuroinflammation in rat model of spinal cord injury. — PubMed · 2021 · Journal Article
- Optogenetic Modulation of Neural Progenitor Cells Improves Neuroregenerative Potential. — PubMed · 2020 · Journal Article
- Selenium-Doped Carbon Quantum Dots Efficiently Ameliorate Secondary Spinal Cord Injury via Scavenging Reactive Oxygen Species. — PubMed · 2020 · Journal Article
- Asiaticoside Inhibits Neuronal Apoptosis and Promotes Functional Recovery After Spinal Cord Injury in Rats. — PubMed · 2020 · Journal Article
- Inflammatory response and oxidative stress attenuated by sulfiredoxin‑1 in neuron‑like cells depends on nuclear factor erythroid‑2‑related factor 2. — PubMed · 2020 · Journal Article
- Investigating the ameliorative effect of alpha-mangostin on development and existing pain in a rat model of neuropathic pain. — PubMed · 2020 · Journal Article
- Matrine protects PC12 cells from lipopolysaccharide-evoked inflammatory injury via upregulation of miR-9. — PubMed · 2020 · Journal Article
- Potential anti-neuroinflammatory NF-кB inhibitors based on 3,4-dihydronaphthalen-1(2H)-one derivatives. — PubMed · 2020 · Journal Article
- Protocatechuic aldehyde mitigates hydrogen peroxide-triggered PC12 cell damage by down-regulating MEG3. — PubMed · 2020 · Journal Article
- Salvianic Acid A Sodium Promotes the Recovery of Motor Function After Spinal Cord Injury in Rats by Reducing Microglia Inflammation through Regulating MIP2/Vdac1/Ndufa12 Signaling Axis. — PubMed · 2020 · Journal Article
- Transplantation of neural stem cells preconditioned with high‑mobility group box 1 facilitates functional recovery after spinal cord injury in rats. — PubMed · 2020 · Journal Article
- Histological and Biochemical Changes in Adult Male Rat Liver after Spinal Cord Injury with Evaluation of the Role of Granulocyte-Colony Stimulating Factor. — PubMed · 2020 · Journal Article
- FBW7 protects against spinal cord injury by mitigating inflammation-associated neuronal apoptosis in mice. — PubMed · 2020 · Journal Article
- Gallic acid attenuates blood-spinal cord barrier disruption by inhibiting Jmjd3 expression and activation after spinal cord injury. — PubMed · 2020 · Journal Article
- Plasma Erythropoietin, IL-17A, and IFNγ as Potential Biomarkers of Motor Function Recovery in a Canine Model of Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Spinal cord injury causes insulin resistance associated with PI3K signaling pathway in hypothalamus. — PubMed · 2020 · Journal Article
- Inhibiting HMGB1-RAGE axis prevents pro-inflammatory macrophages/microglia polarization and affords neuroprotection after spinal cord injury. — PubMed · 2020 · Journal Article
- Erythropoietin-Induced Autophagy Protects Against Spinal Cord Injury and Improves Neurological Function via the Extracellular-Regulated Protein Kinase Signaling Pathway. — PubMed · 2020 · Journal Article
- Injectable Hydrogel Containing Tauroursodeoxycholic Acid for Anti-neuroinflammatory Therapy After Spinal Cord Injury in Rats. — PubMed · 2020 · Journal Article
- Photobiomodulation for spinal cord injury: A systematic review and meta-analysis. — PubMed · 2020 · Journal Article
- Wild Bitter Melon Exerts Anti-Inflammatory Effects by Upregulating Injury-Attenuated CISD2 Expression following Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Attenuation of the inflammatory response and polarization of macrophages by photobiomodulation. — PubMed · 2020 · Journal Article
- l-Theanine improves functional recovery after traumatic spinal cord injury in rats. — PubMed · 2020 · Journal Article
- Muscone suppresses inflammatory responses and neuronal damage in a rat model of cervical spondylotic myelopathy by regulating Drp1-dependent mitochondrial fission. — PubMed · 2020 · Journal Article
- Improved Functional Recovery in Rat Spinal Cord Injury Induced by a Drug Combination Administered with an Implantable Polymeric Delivery System. — PubMed · 2020 · Journal Article
- Alteration of glycinergic receptor expression in lumbar spinal motoneurons is involved in the mechanisms underlying spasticity after spinal cord injury. — PubMed · 2020 · Journal Article
- Can Paraplegia by Disruption of the Spinal Cord Tissue Be Reversed? The Signs of a New Perspective. — PubMed · 2020 · Journal Article
- Effect of VX‑765 on the transcriptome profile of mice spinal cords with acute injury. — PubMed · 2020 · Journal Article
- Hesperidin methyl chalcone alleviates spinal tuberculosis in New Zealand white rabbits by suppressing immune responses. — PubMed · 2020 · Journal Article
- Quercetin mitigates monosodium glutamate-induced excitotoxicity of the spinal cord motoneurons in aged rats via p38 MAPK inhibition. — PubMed · 2020 · Journal Article
- Therapeutic Effects of Minocycline Pretreatment in the Locomotor and Sensory Complications of Spinal Cord Injury in an Animal Model. — PubMed · 2020 · Journal Article
- HDAC8 Inhibition Reduces Lesional Iba-1+ Cell Infiltration after Spinal Cord Injury without Effects on Functional Recovery. — PubMed · 2020 · Journal Article
- Curcumin protects BV2 cells against lipopolysaccharide-induced injury via adjusting the miR-362-3p/TLR4 axis. — PubMed · 2020 · Journal Article
- Transplantation of activated olfactory ensheathing cells by curcumin strengthens regeneration and recovery of function after spinal cord injury in rats. — PubMed · 2020 · Journal Article
- Effects of combined treatment of minocycline and methylprednisolone on the expression of tumor necrosis factor alpha and interleukine-6 in experimental spinal cord injury: a light and electron microscopic study. — PubMed · 2020 · Journal Article
- Oral treatment with glycyrrhizin inhibits NLRP3 inflammasome activation and promotes microglial M2 polarization after traumatic spinal cord injury. — PubMed · 2020 · Journal Article
- Why do anti-inflammatory signals of bone marrow-derived stromal cells improve neurodegenerative conditions where anti-inflammatory drugs fail? — PubMed · 2020 · Journal Article
- Riluzole improves functional recovery after acute spinal cord injury in rats and may be associated with changes in spinal microglia/macrophages polarization. — PubMed · 2020 · Journal Article
- MicroRNA-129-5p alleviates spinal cord injury in mice via suppressing the apoptosis and inflammatory response through HMGB1/TLR4/NF-κB pathway. — PubMed · 2020 · Journal Article
- Oleanolic acid inhibits mouse spinal cord injury through suppressing inflammation and apoptosis via the blockage of p38 and JNK MAPKs. — PubMed · 2020 · Journal Article
- Pharmacokinetics and anti-inflammatory effect of naproxen in rats with acute and subacute spinal cord injury. — PubMed · 2020 · Journal Article
- Dihydrotanshinone I Alleviates Spinal Cord Injury via Suppressing Inflammatory Response, Oxidative Stress and Apoptosis in Rats. — PubMed · 2020 · Journal Article
- Stress Pathway Modulation Is Detrimental or Ineffective for Functional Recovery after Spinal Cord Injury in Mice. — PubMed · 2020 · Journal Article
- Hesperidin improves motor disability in rat spinal cord injury through anti-inflammatory and antioxidant mechanism via Nrf-2/HO-1 pathway. — PubMed · 2020 · Journal Article
- Transplantation of M2-Deviated Microglia Promotes Recovery of Motor Function after Spinal Cord Injury in Mice. — PubMed · 2020 · Journal Article
- Alkaline-phosphatase triggered self-assemblies enhances the anti-inflammatory property of methylprednisolone in spinal cord injury. — PubMed · 2020 · Journal Article
- Anti-inflammatory Effect of AZD6244 on Acrolein-Induced Neuroinflammation. — PubMed · 2020 · Journal Article
- A Pivotal Role of the Nrf2 Signaling Pathway in Spinal Cord Injury: A Prospective Therapeutics Study. — PubMed · 2020 · Journal Article
- Investigation of Neuroprotective and Therapeutic Effects of Hesperidin in Experimental Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Protective effect of Oxymatrine against acute spinal cord injury in rats via modulating oxidative stress, inflammation and apoptosis. — PubMed · 2020 · Journal Article
- The Effect of Autologous Adipose Tissue-Derived Mesenchymal Stem Cells' Therapy in the Treatment of Chronic Posttraumatic Spinal Cord Injury in a Domestic Ferret Patient. — PubMed · 2020 · Journal Article
- Lentivirus-mediated downregulation of α-synuclein reduces neuroinflammation and promotes functional recovery in rats with spinal cord injury. — PubMed · 2019 · Journal Article
- Curcumin Alleviates Lipopolysaccharide (LPS)-Activated Neuroinflammation via Modulation of miR-199b-5p/IκB Kinase β (IKKβ)/Nuclear Factor Kappa B (NF-κB) Pathway in Microglia. — PubMed · 2019 · Journal Article
- Insulin-like growth factor-1 enhances neuroprotective effects of neural stem cell exosomes after spinal cord injury via an miR-219a-2-3p/YY1 mechanism. — PubMed · 2019 · Journal Article
- Risk factors associated with progressive myelomalacia in dogs with complete sensorimotor loss following intervertebral disc extrusion: a retrospective case-control study. — PubMed · 2019 · Journal Article
- Bisperoxovanadium induces M2-type macrophages and promotes functional recovery after spinal cord injury. — PubMed · 2019 · Journal Article
- Dexmedetomidine modulates neuroinflammation and improves outcome via alpha2-adrenergic receptor signaling after rat spinal cord injury. — PubMed · 2019 · Journal Article
- Effect of curcumin on the inflammatory reaction and functional recovery after spinal cord injury in a hyperglycemic rat model. — PubMed · 2019 · Journal Article
- Galantamine improves functional recovery and reduces lesion size in a rat model of spinal cord injury. — PubMed · 2019 · Journal Article
- Geniposide protects PC12 cells from lipopolysaccharide-evoked inflammatory injury via up-regulation of miR-145-5p. — PubMed · 2019 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 13 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1741999 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 17 · this programme has 2063 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("immunomodulation" OR "anti-inflammatory") - Crossref
spinal cord injury immunomodulation anti-inflammatory - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Immunomodulating Agents"[MeSH Terms] OR "Anti-Inflammatory Agents"[MeSH Terms] OR "immunomodulation"[Title/Abstract] OR "anti-inflammatory"[Title/Abstract])