A subject this map covers
Immunomodulatory drugs
Part of: Inflammation and immune response
What belongs here
Drugs that change the immune response after injury, other than steroids and minocycline, which have their own concepts.
What does not belong here, however close it looks
Immunosuppression to keep a graft alive is part of cell therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 678 records · 1968–2026
- Indexed as work in animals: 932 records · 1982–2026
- Indexed as laboratory work: 34 records · 1991–2026
- The source has not said who or what was studied: 437 records · 1977–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
2081 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Protective effects of dantrolene and methylprednisolone against spinal cord injury-induced early oxidative damage in rabbit bladder: A comparative experimental study. — PubMed · 2019 · Journal Article
- Regenerative rehabilitation: exploring the synergistic effects of rehabilitation and implantation of a bio-functional scaffold in enhancing nerve regeneration. — PubMed · 2019 · Journal Article
- Ameliorative effects of echinacoside against spinal cord injury via inhibiting NLRP3 inflammasome signaling pathway. — PubMed · 2019 · Journal Article
- The Importance of Natural Antioxidants in the Treatment of Spinal Cord Injury in Animal Models: An Overview. — PubMed · 2019 · Journal Article
- Quercetin prevents necroptosis of oligodendrocytes by inhibiting macrophages/microglia polarization to M1 phenotype after spinal cord injury in rats. — PubMed · 2019 · Journal Article
- Berberine enhances survival and axonal regeneration of motoneurons following spinal root avulsion and re-implantation in rats. — PubMed · 2019 · Journal Article
- Predictors of urinary or fecal incontinence in dogs with thoracolumbar acute non-compressive nucleus pulposus extrusion. — PubMed · 2019 · Journal Article
- A refinement approach in a mouse model of rehabilitation research. Analgesia strategy, reduction approach and infrared thermography in spinal cord injury. — PubMed · 2019 · Comparative Study
- Neuroprotective role of icariin in experimental spinal cord injury via its antioxidant, anti‑neuroinflammatory and anti‑apoptotic properties. — PubMed · 2019 · Journal Article
- TMEM16F inhibition limits pain-associated behavior and improves motor function by promoting microglia M2 polarization in mice. — PubMed · 2019 · Journal Article
- Neural stem cell small extracellular vesicle-based delivery of 14-3-3t reduces apoptosis and neuroinflammation following traumatic spinal cord injury by enhancing autophagy by targeting Beclin-1. — PubMed · 2019 · Journal Article
- Effect of M2 macrophage adoptive transfer on transcriptome profile of injured spinal cords in rats. — PubMed · 2019 · Journal Article
- Endogenous Interleukin-10 Deficiency Exacerbates Vascular Pathology in Traumatic Cervical Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Inhibition of NOX2 signaling limits pain-related behavior and improves motor function in male mice after spinal cord injury: Participation of IL-10/miR-155 pathways. — PubMed · 2019 · Journal Article
- A hydrogel engineered to deliver minocycline locally to the injured cervical spinal cord protects respiratory neural circuitry and preserves diaphragm function. — PubMed · 2019 · Journal Article
- BET protein inhibition regulates cytokine production and promotes neuroprotection after spinal cord injury. — PubMed · 2019 · Journal Article
- Sodium Butyrate Exerts Neuroprotective Effects in Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Characterizing the Neuroprotective Effects of S/B Remedy (Scutellaria baicalensis Georgi and Bupleurum scorzonerifolfium Willd) in Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Inhibition of NLRP3 inflammasome attenuates spinal cord injury-induced lung injury in mice. — PubMed · 2019 · Journal Article
- Macrolide derivatives reduce proinflammatory macrophage activation and macrophage-mediated neurotoxicity. — PubMed · 2019 · Journal Article
- Spinal cord injury by clip-compression induces anxiety and depression-like behaviours in female rats: The role of the inflammatory response. — PubMed · 2019 · Journal Article
- Trehalose attenuates spinal cord injury through the regulation of oxidative stress, inflammation and GFAP expression in rats. — PubMed · 2019 · Journal Article
- Sustained interleukin-10 delivery reduces inflammation and improves motor function after spinal cord injury. — PubMed · 2019 · Journal Article
- Macrophage migration inhibitory factor facilitates prostaglandin E(2) production of astrocytes to tune inflammatory milieu following spinal cord injury. — PubMed · 2019 · Journal Article
- Effects of astaxanthin on sensory-motor function in a compression model of spinal cord injury: Involvement of ERK and AKT signalling pathway. — PubMed · 2019 · Journal Article
- Intrathecal transplantation of Wharton's jelly mesenchymal stem cells suppresses the NLRP1 inflammasome in the rat model of spinal cord injury. — PubMed · 2019 · Journal Article
- Progesterone effects on oligodendrocyte differentiation in injured spinal cord. — PubMed · 2019 · Journal Article
- Role of Na(V)1.6 and Na(V)β4 Sodium Channel Subunits in a Rat Model of Low Back Pain Induced by Compression of the Dorsal Root Ganglia. — PubMed · 2019 · Journal Article
- PPAR-γ Activation Exerts an Anti-inflammatory Effect by Suppressing the NLRP3 Inflammasome in Spinal Cord-Derived Neurons. — PubMed · 2019 · Journal Article
- Astrocyte progenitor transplantation promotes regeneration of bulbospinal respiratory axons, recovery of diaphragm function, and a reduced macrophage response following cervical spinal cord injury. — PubMed · 2019 · Journal Article
- Resveratrol treatment of spinal cord injury in rat model. — PubMed · 2019 · Journal Article
- Polysialic-Acid-Based Micelles Promote Neural Regeneration in Spinal Cord Injury Therapy. — PubMed · 2019 · Journal Article
- Low frequency pulsed electromagnetic field promotes the recovery of neurological function after spinal cord injury in rats. — PubMed · 2019 · Evaluation Study
- Resveratrol alleviates lipopolysaccharide-induced inflammation in PC-12 cells and in rat model. — PubMed · 2019 · Journal Article
- An anti-inflammatory peptide and brain-derived neurotrophic factor-modified hyaluronan-methylcellulose hydrogel promotes nerve regeneration in rats with spinal cord injury. — PubMed · 2019 · Journal Article
- Polydatin attenuates spinal cord injury in rats by inhibiting oxidative stress and microglia apoptosis via Nrf2/HO-1 pathway. — PubMed · 2019 · Journal Article
- Evaluation of the neuroprotective effects of anti-inflammatory drugs in experimental spinal cord damage. — PubMed · 2019 · Journal Article
- Investigation of the Effect of Alemtuzumab in an Experimental Spinal Cord Trauma Model in Rats. — PubMed · 2019 · Journal Article
- Myxoma virus derived immune modulating proteins, M-T7 and Serp-1, reduce early inflammation after spinal cord injury in the rat model. — PubMed · 2019 · Journal Article
- RETRACTED: Tanshinone IIA alleviates oxidative damage after spinal cord injury in vitro and in vivo through up-regulating miR-124. — PubMed · 2019 · Journal Article The source marks this record as retracted.
- Ursodeoxycholic Acid Inhibits Inflammatory Responses and Promotes Functional Recovery After Spinal Cord Injury in Rats. — PubMed · 2019 · Journal Article
- Minocycline Reduces the Severity of Autonomic Dysreflexia after Experimental Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Therapeutic effects of simultaneous Photobiomodulation therapy (PBMT) and Meloxicam administration on experimental acute spinal cord injury: Rat animal model. — PubMed · 2018 · Journal Article
- Reducing inflammation through delivery of lentivirus encoding for anti-inflammatory cytokines attenuates neuropathic pain after spinal cord injury. — PubMed · 2018 · Journal Article
- Anti-inflammatory effects of Metformin improve the neuropathic pain and locomotor activity in spinal cord injured rats: introduction of an alternative therapy. — PubMed · 2018 · Journal Article
- Bromodomain and extraterminal domain-containing protein inhibition attenuates acute inflammation after spinal cord injury. — PubMed · 2018 · Journal Article
- Dexmedetomidine Mitigates Microglia-Mediated Neuroinflammation through Upregulation of Programmed Cell Death Protein 1 in a Rat Spinal Cord Injury Model. — PubMed · 2018 · Journal Article
- Effects of an Intraparenchymal Injection of Lidocaine in the Rat Cervical Spinal Cord. — PubMed · 2018 · Journal Article
- Astaxanthin attenuates neuroinflammation contributed to the neuropathic pain and motor dysfunction following compression spinal cord injury. — PubMed · 2018 · Journal Article
- Ketogenic diet attenuates oxidative stress and inflammation after spinal cord injury by activating Nrf2 and suppressing the NF-κB signaling pathways. — PubMed · 2018 · Journal Article
- Tetramethylpyrazine ameliorates experimental autoimmune encephalomyelitis by modulating the inflammatory response. — PubMed · 2018 · Journal Article
- Baicalin effects on rats with spinal cord injury by anti-inflammatory and regulating the serum metabolic disorder. — PubMed · 2018 · Journal Article
- Early Targeting of L-Selectin on Leukocytes Promotes Recovery after Spinal Cord Injury, Implicating Novel Mechanisms of Pathogenesis. — PubMed · 2018 · Journal Article
- Neuroprotection and immunomodulation following intraspinal axotomy of motoneurons by treatment with adult mesenchymal stem cells. — PubMed · 2018 · Journal Article
- Methylprednisolone treatment enhances early recovery following surgical decompression for degenerative cervical myelopathy without compromise to the systemic immune system. — PubMed · 2018 · Journal Article
- Effect evaluation of methylprednisolone plus mitochondrial division inhibitor-1 on spinal cord injury rats. — PubMed · 2018 · Journal Article
- Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway. — PubMed · 2018 · Journal Article
- The Effect of Electromagnetic Fields on Post-Operative Pain and Locomotor Recovery in Dogs with Acute, Severe Thoracolumbar Intervertebral Disc Extrusion: A Randomized Placebo-Controlled, Prospective Clinical Trial. — PubMed · 2018 · Clinical Trial, Veterinary
- Flufenamic acid inhibits secondary hemorrhage and BSCB disruption after spinal cord injury. — PubMed · 2018 · Journal Article
- Overexpression of HIPK2 attenuates spinal cord injury in rats by modulating apoptosis, oxidative stress, and inflammation. — PubMed · 2018 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 13 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1741999 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 17 · this programme has 2063 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("immunomodulation" OR "anti-inflammatory") - Crossref
spinal cord injury immunomodulation anti-inflammatory - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Immunomodulating Agents"[MeSH Terms] OR "Anti-Inflammatory Agents"[MeSH Terms] OR "immunomodulation"[Title/Abstract] OR "anti-inflammatory"[Title/Abstract])