A subject this map covers
Immunomodulatory drugs
Part of: Inflammation and immune response
What belongs here
Drugs that change the immune response after injury, other than steroids and minocycline, which have their own concepts.
What does not belong here, however close it looks
Immunosuppression to keep a graft alive is part of cell therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 678 records · 1968–2026
- Indexed as work in animals: 932 records · 1982–2026
- Indexed as laboratory work: 34 records · 1991–2026
- The source has not said who or what was studied: 437 records · 1977–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
2081 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Anti-inflammatory effect of Mongolian drug Naru-3 on traumatic spinal cord injury and its mechanism of action. — PubMed · 2018 · Evaluation Study
- Neural crest stem cells protect spinal cord neurons from excitotoxic damage and inhibit glial activation by secretion of brain-derived neurotrophic factor. — PubMed · 2018 · Journal Article
- Panax quinquefolius saponin inhibits endoplasmic reticulum stress-mediated apoptosis and neurite injury and improves functional recovery in a rat spinal cord injury model. — PubMed · 2018 · Journal Article
- Ecto-5'-nucleotidase (CD73) attenuates inflammation after spinal cord injury by promoting macrophages/microglia M2 polarization in mice. — PubMed · 2018 · Journal Article
- Valproic acid attenuates traumatic spinal cord injury-induced inflammation via STAT1 and NF-κB pathway dependent of HDAC3. — PubMed · 2018 · Journal Article
- Aspirin suppresses neuronal apoptosis, reduces tissue inflammation, and restrains astrocyte activation by activating the Nrf2/HO-1 signaling pathway. — PubMed · 2018 · Journal Article
- Nafamostat mesilate attenuates inflammation and apoptosis and promotes locomotor recovery after spinal cord injury. — PubMed · 2018 · Journal Article
- The human natural killer-1 (HNK-1) glycan mimetic ursolic acid promotes functional recovery after spinal cord injury in mouse. — PubMed · 2018 · Journal Article
- A Single Dose of Atorvastatin Applied Acutely after Spinal Cord Injury Suppresses Inflammation, Apoptosis, and Promotes Axon Outgrowth, Which Might Be Essential for Favorable Functional Outcome. — PubMed · 2018 · Journal Article
- Class IIa HDACs inhibitor TMP269 promotes M1 polarization of macrophages after spinal cord injury. — PubMed · 2018 · Journal Article
- Triggering of Autophagy by Baicalein in Response to Apoptosis after Spinal Cord Injury: Possible Involvement of the PI3K Activation. — PubMed · 2018 · Journal Article
- Adenovirus-delivered GFP-HO-1C[INCREMENT]23 attenuates blood-spinal cord barrier permeability after rat spinal cord contusion. — PubMed · 2018 · Journal Article
- Promotion of neurological recovery in rat spinal cord injury by mesenchymal stem cells loaded on nerve-guided collagen scaffold through increasing alternatively activated macrophage polarization. — PubMed · 2018 · Journal Article
- Sustained reversal of central neuropathic pain induced by a single intrathecal injection of adenosine A(2A) receptor agonists. — PubMed · 2018 · Journal Article
- Anti-inflammatory effect of Tauroursodeoxycholic acid in RAW 264.7 macrophages, Bone marrow-derived macrophages, BV2 microglial cells, and spinal cord injury. — PubMed · 2018 · Journal Article
- Blockade of Interleukin-7 Receptor Shapes Macrophage Alternative Activation and Promotes Functional Recovery After Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Albumin-Conjugated Lipid-Based Multilayered Nanoemulsion Improves Drug Specificity and Anti-Inflammatory Potential at the Spinal Cord Injury gSite after Intravenous Administration. — PubMed · 2018 · Journal Article
- Estrogen Attenuates Local Inflammasome Expression and Activation after Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Salidroside attenuates neuroinflammation and improves functional recovery after spinal cord injury through microglia polarization regulation. — PubMed · 2018 · Journal Article
- Administration of chlorogenic acid alleviates spinal cord injury via TLR4/NF‑κB and p38 signaling pathway anti‑inflammatory activity. — PubMed · 2018 · Journal Article
- Anti-inflammatory compound curcumin and mesenchymal stem cells in the treatment of spinal cord injury in rats. — PubMed · 2018 · Journal Article
- Chinese Angelica Polysaccharide (CAP) Alleviates LPS-Induced Inflammation and Apoptosis by Down-Regulating COX-1 in PC12 Cells. — PubMed · 2018 · Journal Article
- Gambogic acid inhibits spinal cord injury and inflammation through suppressing the p38 and Akt signaling pathways. — PubMed · 2018 · Journal Article
- Lipoxin A4 protects against spinal cord injury via regulating Akt/nuclear factor (erythroid-derived 2)-like 2/heme oxygenase-1 signaling. — PubMed · 2018 · Journal Article
- Mesenchymal Stem Cell-Derived Exosomes Reduce A1 Astrocytes via Downregulation of Phosphorylated NFκB P65 Subunit in Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Methods for Assessing Serpins as Neuroprotective Therapeutics. — PubMed · 2018 · Journal Article
- Systemic Administration of Exosomes Released from Mesenchymal Stromal Cells Attenuates Apoptosis, Inflammation, and Promotes Angiogenesis after Spinal Cord Injury in Rats. — PubMed · 2017 · Journal Article
- Withaferin A protects against spinal cord injury by inhibiting apoptosis and inflammation in mice. — PubMed · 2017 · Journal Article
- Anterior chamber associated immune deviation used as a neuroprotective strategy in rats with spinal cord injury. — PubMed · 2017 · Journal Article
- Maresin 1 Promotes Inflammatory Resolution, Neuroprotection, and Functional Neurological Recovery After Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Epothilone B impairs functional recovery after spinal cord injury by increasing secretion of macrophage colony-stimulating factor. — PubMed · 2017 · Journal Article
- Fumaric Acid Esters Attenuate Secondary Degeneration after Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Myricitrin decreases traumatic injury of the spinal cord and exhibits antioxidant and anti‑inflammatory activities in a rat model via inhibition of COX‑2, TGF‑β1, p53 and elevation of Bcl‑2/Bax signaling pathway. — PubMed · 2017 · Journal Article
- Effect of curcumin on acute spinal cord injury in mice via inhibition of inflammation and TAK1 pathway. — PubMed · 2017 · Journal Article
- PPAR-α Modulates the Anti-Inflammatory Effect of Melatonin in the Secondary Events of Spinal Cord Injury. — PubMed · 2017 · Journal Article The source marks this record as retracted.
- The synthetic cannabinoid WIN55212-2 ameliorates traumatic spinal cord injury via inhibition of GAPDH/Siah1 in a CB2-receptor dependent manner. — PubMed · 2017 · Journal Article
- The effectiveness of the anti-CD11d treatment is reduced in rat models of spinal cord injury that produce significant levels of intraspinal hemorrhage. — PubMed · 2017 · Journal Article
- Effects of Bone-Marrow-Derived MSC Transplantation on Functional Recovery in a Rat Model of Spinal Cord Injury: Comparisons of Transplant Locations and Cell Concentrations. — PubMed · 2017 · Journal Article
- T1R1/T1R3 Taste Receptor Suppresses Granulocyte-Mediated Neuroinflammation after Spinal Cord Injury. — PubMed · 2017 · Journal Article
- FK506 Attenuates the Inflammation in Rat Spinal Cord Injury by Inhibiting the Activation of NF-κB in Microglia Cells. — PubMed · 2017 · Journal Article
- Schisandrin B attenuates the inflammatory response, oxidative stress and apoptosis induced by traumatic spinal cord injury via inhibition of p53 signaling in adult rats. — PubMed · 2017 · Journal Article
- Neuroprotective effects of astaxanthin in a rat model of spinal cord injury. — PubMed · 2017 · Journal Article
- Hydrogen-rich saline attenuates spinal cord hemisection-induced testicular injury in rats. — PubMed · 2017 · Journal Article
- Bee Venom Acupuncture Reduces Interleukin-6, Increases Interleukin-10, and Induces Locomotor Recovery in a Model of Spinal Cord Compression. — PubMed · 2017 · Journal Article
- Nano-carrier mediated co-delivery of methyl prednisolone and minocycline for improved post-traumatic spinal cord injury conditions in rats. — PubMed · 2017 · Journal Article
- Cordycepin-enriched WIB-801C from Cordyceps militaris improves functional recovery by attenuating blood-spinal cord barrier disruption after spinal cord injury. — PubMed · 2017 · Journal Article
- Sophorolipid Butyl Ester Diacetate Does Not Affect Macrophage Polarization but Enhances Astrocytic Glial Fibrillary Acidic Protein Expression at Micromolar Concentrations in Vitro. — PubMed · 2017 · Journal Article
- Functional and structural changes of the urinary bladder following spinal cord injury; treatment with alpha lipoic acid. — PubMed · 2017 · Journal Article
- Spinal cord injury effectively ameliorated by neuroprotective effects of rosmarinic acid. — PubMed · 2017 · Journal Article
- An Agonist of the Protective Factor SIRT1 Improves Functional Recovery and Promotes Neuronal Survival by Attenuating Inflammation after Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Neural Stem Cell-Conditioned Medium Suppresses Inflammation and Promotes Spinal Cord Injury Recovery. — PubMed · 2017 · Journal Article
- The Effects of Co-transplantation of Olfactory Ensheathing Cells and Schwann Cells on Local Inflammation Environment in the Contused Spinal Cord of Rats. — PubMed · 2017 · Journal Article
- The protective effect of curcumin in Olfactory Ensheathing Cells exposed to hypoxia. — PubMed · 2017 · Journal Article
- Methane ameliorates spinal cord ischemia-reperfusion injury in rats: Antioxidant, anti-inflammatory and anti-apoptotic activity mediated by Nrf2 activation. — PubMed · 2017 · Journal Article
- Neurobiological Effects of Morphine after Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Lanthionine ketimine ester promotes locomotor recovery after spinal cord injury by reducing neuroinflammation and promoting axon growth. — PubMed · 2017 · Journal Article
- Protease-Activated Receptor-1 Supports Locomotor Recovery by Biased Agonist Activated Protein C after Contusive Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Curcumin inhibits glial scar formation by suppressing astrocyte-induced inflammation and fibrosis in vitro and in vivo. — PubMed · 2017 · Journal Article
- Synchrotron radiation micro-CT as a novel tool to evaluate the effect of agomir-210 in a rat spinal cord injury model. — PubMed · 2017 · Journal Article
- Immunization with neural derived peptides plus scar removal induces a permissive microenvironment, and improves locomotor recovery after chronic spinal cord injury. — PubMed · 2017 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-09-29 Collection window: 2026-09-16 – 2026-09-29 | matched in this collection walk 0 · accumulated records across collection walks 13 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1741999 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 17 · accumulated records across collection walks 2063 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("immunomodulation" OR "anti-inflammatory") - Crossref
spinal cord injury immunomodulation anti-inflammatory - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Immunomodulating Agents"[MeSH Terms] OR "Anti-Inflammatory Agents"[MeSH Terms] OR "immunomodulation"[Title/Abstract] OR "anti-inflammatory"[Title/Abstract])