A subject this map covers
Immunomodulatory drugs
Part of: Inflammation and immune response
What belongs here
Drugs that change the immune response after injury, other than steroids and minocycline, which have their own concepts.
What does not belong here, however close it looks
Immunosuppression to keep a graft alive is part of cell therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 678 records · 1968–2026
- Indexed as work in animals: 932 records · 1982–2026
- Indexed as laboratory work: 34 records · 1991–2026
- The source has not said who or what was studied: 437 records · 1977–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
2081 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Combined polymer-curcumin conjugate and ependymal progenitor/stem cell treatment enhances spinal cord injury functional recovery. — PubMed · 2017 · Journal Article
- Effect of Asiatic Acid on the Treatment of Spinal Cord Injury: An Experimental Study in Rats. — PubMed · 2017 · Journal Article
- Effect of Shikonin on Spinal Cord Injury in Rats Via Regulation of HMGB1/TLR4/NF-kB Signaling Pathway. — PubMed · 2017 · Journal Article
- Effects of Atorvastatin on Experimental Spinal Cord Ischemia-Reperfusion Injury in Rabbits. — PubMed · 2017 · Journal Article
- Local delivery of minocycline from metal ion-assisted self-assembled complexes promotes neuroprotection and functional recovery after spinal cord injury. — PubMed · 2017 · Journal Article
- Methylprednisolone Administration Following Spinal Cord Injury Reduces Aquaporin 4 Expression and Exacerbates Edema. — PubMed · 2017 · Journal Article
- Cell-Based Delivery of Interleukin-13 Directs Alternative Activation of Macrophages Resulting in Improved Functional Outcome after Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Effects of melatonin on severe crush spinal cord injury-induced reactive astrocyte and scar formation. — PubMed · 2016 · Journal Article
- IL-4 drives microglia and macrophages toward a phenotype conducive for tissue repair and functional recovery after spinal cord injury. — PubMed · 2016 · Journal Article
- Naringenin inhibits spinal cord injury-induced activation of neutrophils through miR-223. — PubMed · 2016 · Journal Article
- Aescin reduces oxidative stress and provides neuroprotection in experimental traumatic spinal cord injury. — PubMed · 2016 · Journal Article
- B-Cell Depletion with CD20 Antibodies as New Approach in the Treatment of Inflammatory and Immunological Events Associated with Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Is the Wnt/β-catenin pathway involved in the anti-inflammatory activity of glucocorticoids in spinal cord injury? — PubMed · 2016 · Journal Article
- Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Is Constitutively Expressed in Adult Central Nervous System (CNS) and Associated with Astrocyte-mediated Glial Scar Formation following Spinal Cord Injury. — PubMed · 2016 · Journal Article
- A Coral-Derived Compound Improves Functional Recovery after Spinal Cord Injury through Its Antiapoptotic and Anti-Inflammatory Effects. — PubMed · 2016 · Journal Article
- Metformin preconditioning provide neuroprotection through enhancement of autophagy and suppression of inflammation and apoptosis after spinal cord injury. — PubMed · 2016 · Journal Article
- Anti-inflammatory effects of ADAMTS-4 in a mouse model of ischemic stroke. — PubMed · 2016 · Journal Article
- Methylprednisolone sodium succinate reduces spinal cord swelling but does not affect recovery of dogs with surgically treated thoracolumbar intervertebral disk herniation. — PubMed · 2016 · Controlled Clinical Trial
- Red LED photobiomodulation reduces pain hypersensitivity and improves sensorimotor function following mild T10 hemicontusion spinal cord injury. — PubMed · 2016 · Journal Article
- Anti-Inflammatory Mechanism of Neural Stem Cell Transplantation in Spinal Cord Injury. — PubMed · 2016 · Journal Article
- The Association of Palmitoylethanolamide with Luteolin Decreases Autophagy in Spinal Cord Injury. — PubMed · 2016 · Journal Article The source marks this record as retracted.
- C-C motif chemokine ligand 20 regulates neuroinflammation following spinal cord injury via Th17 cell recruitment. — PubMed · 2016 · Journal Article
- Effect of Progesterone Therapy on TNF-α and iNOS Gene Expression in Spinal Cord Injury Model. — PubMed · 2016 · Journal Article
- Silencing spinal interneurons inhibits immune suppressive autonomic reflexes caused by spinal cord injury. — PubMed · 2016 · Journal Article
- Rescuing macrophage normal function in spinal cord injury with embryonic stem cell conditioned media. — PubMed · 2016 · Journal Article
- Effect of Estrogen Therapy on TNF-α and iNOS Gene Expression in Spinal Cord Injury Model. — PubMed · 2016 · Journal Article
- Rosiglitazone attenuates inflammation and CA3 neuronal loss following traumatic brain injury in rats. — PubMed · 2016 · Journal Article
- Lipoxin A4 inhibits microglial activation and reduces neuroinflammation and neuropathic pain after spinal cord hemisection. — PubMed · 2016 · Journal Article
- Treatment with bone marrow mesenchymal stem cells combined with plumbagin alleviates spinal cord injury by affecting oxidative stress, inflammation, apoptotis and the activation of the Nrf2 pathway. — PubMed · 2016 · Journal Article
- Differential effects of myelin basic protein-activated Th1 and Th2 cells on the local immune microenvironment of injured spinal cord. — PubMed · 2016 · Journal Article
- Spontaneous Recovery of Reflex Voiding Following Spinal Cord Injury Mediated by Anti-inflammatory and Neuroprotective Factors. — PubMed · 2016 · Journal Article
- Cyclic AMP is a key regulator of M1 to M2a phenotypic conversion of microglia in the presence of Th2 cytokines. — PubMed · 2016 · Journal Article
- An in vivo model of anti-inflammatory activity of subdural dexamethasone following the spinal cord injury. — PubMed · 2016 · Journal Article
- A Placebo-Controlled, Prospective, Randomized Clinical Trial of Polyethylene Glycol and Methylprednisolone Sodium Succinate in Dogs with Intervertebral Disk Herniation. — PubMed · 2016 · Journal Article
- Early modulation of pro-inflammatory microglia by minocycline loaded nanoparticles confers long lasting protection after spinal cord injury. — PubMed · 2016 · Journal Article
- Gastrodin ameliorates spinal cord injury via antioxidant and anti-inflammatory effects. — PubMed · 2016 · Journal Article
- Genetic Ablation of Soluble TNF Does Not Affect Lesion Size and Functional Recovery after Moderate Spinal Cord Injury in Mice. — PubMed · 2016 · Journal Article
- The Neuroprotective Effect of Puerarin in Acute Spinal Cord Injury Rats. — PubMed · 2016 · Journal Article
- Neuroprotective effect of allicin in a rat model of acute spinal cord injury. — PubMed · 2015 · Journal Article
- Asiaticoside attenuates the effects of spinal cord injury through antioxidant and anti‑inflammatory effects, and inhibition of the p38‑MAPK mechanism. — PubMed · 2015 · Journal Article
- CISD2 serves a novel role as a suppressor of nitric oxide signalling and curcumin increases CISD2 expression in spinal cord injuries. — PubMed · 2015 · Journal Article
- Antioxidant and anti-inflammatory effects of intravenously injected adipose derived mesenchymal stem cells in dogs with acute spinal cord injury. — PubMed · 2015 · Evaluation Study
- Azithromycin drives alternative macrophage activation and improves recovery and tissue sparing in contusion spinal cord injury. — PubMed · 2015 · Journal Article
- A functional progesterone receptor is required for immunomodulation, reduction of reactive gliosis and survival of oligodendrocyte precursors in the injured spinal cord. — PubMed · 2015 · Journal Article
- Age decreases macrophage IL-10 expression: Implications for functional recovery and tissue repair in spinal cord injury. — PubMed · 2015 · Journal Article
- Effect of rutin on spinal cord injury through inhibition of the expression of MIP-2 and activation of MMP-9, and downregulation of Akt phosphorylation. — PubMed · 2015 · Journal Article
- Mangiferin attenuates contusive spinal cord injury in rats through the regulation of oxidative stress, inflammation and the Bcl‑2 and Bax pathway. — PubMed · 2015 · Journal Article
- Multifunctional nanoparticles for gene delivery and spinal cord injury. — PubMed · 2015 · Journal Article
- Treatment with curcumin alleviates sublesional bone loss following spinal cord injury in rats. — PubMed · 2015 · Journal Article
- Bone marrow mesenchymal stem cells combined with minocycline improve spinal cord injury in a rat model. — PubMed · 2015 · Journal Article
- Temporal kinetics of macrophage polarization in the injured rat spinal cord. — PubMed · 2015 · Journal Article
- Nanoparticle Estrogen in Rat Spinal Cord Injury Elicits Rapid Anti-Inflammatory Effects in Plasma, Cerebrospinal Fluid, and Tissue. — PubMed · 2015 · Journal Article
- Delivery of Alginate Scaffold Releasing Two Trophic Factors for Spinal Cord Injury Repair. — PubMed · 2015 · Journal Article
- CD11d integrin blockade reduces the systemic inflammatory response syndrome after traumatic brain injury in rats. — PubMed · 2015 · Journal Article
- Lack of galectin-3 improves the functional outcome and tissue sparing by modulating inflammatory response after a compressive spinal cord injury. — PubMed · 2015 · Journal Article
- Plumbagin Protects Against Spinal Cord Injury-induced Oxidative Stress and Inflammation in Wistar Rats through Nrf-2 Upregulation. — PubMed · 2015 · Journal Article
- The influence of low-level laser irradiation on spinal cord injuries following ischemia-reperfusion in rats. — PubMed · 2015 · Evaluation Study
- Preclinical efficacy of Dexmedetomidine on spinal cord injury provoked oxidative renal damage. — PubMed · 2015 · Journal Article
- Protective effects of gallic acid against spinal cord injury-induced oxidative stress. — PubMed · 2015 · Journal Article
- S-Nitrosoglutathione protects the spinal bladder: novel therapeutic approach to post-spinal cord injury bladder remodeling. — PubMed · 2015 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-09-29 Collection window: 2026-09-16 – 2026-09-29 | matched in this collection walk 0 · accumulated records across collection walks 13 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1741999 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 17 · accumulated records across collection walks 2063 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("immunomodulation" OR "anti-inflammatory") - Crossref
spinal cord injury immunomodulation anti-inflammatory - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Immunomodulating Agents"[MeSH Terms] OR "Anti-Inflammatory Agents"[MeSH Terms] OR "immunomodulation"[Title/Abstract] OR "anti-inflammatory"[Title/Abstract])