A subject this map covers
Immunomodulatory drugs
Part of: Inflammation and immune response
What belongs here
Drugs that change the immune response after injury, other than steroids and minocycline, which have their own concepts.
What does not belong here, however close it looks
Immunosuppression to keep a graft alive is part of cell therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 678 records · 1968–2026
- Indexed as work in animals: 932 records · 1982–2026
- Indexed as laboratory work: 34 records · 1991–2026
- The source has not said who or what was studied: 437 records · 1977–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
2081 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Angelica Sinensis attenuates inflammatory reaction in experimental rat models having spinal cord injury. — PubMed · 2015 · Journal Article
- Anti-Apoptotic Effects of Dapsone After Spinal Cord Injury in Rats. — PubMed · 2015 · Journal Article
- Curcumin improves neural function after spinal cord injury by the joint inhibition of the intracellular and extracellular components of glial scar. — PubMed · 2015 · Journal Article
- Anti-inflammatory Mechanism of Bone Marrow Mesenchymal Stem Cell Transplantation in Rat Model of Spinal Cord Injury. — PubMed · 2015 · Journal Article
- Protective effects of Vitamin C against spinal cord injury-induced renal damage through suppression of NF-κB and proinflammatory cytokines. — PubMed · 2015 · Journal Article
- Feasibility and safety of intrathecal transplantation of autologous bone marrow mesenchymal stem cells in horses. — PubMed · 2015 · Journal Article
- Honokiol downregulates Kruppel-like factor 4 expression, attenuates inflammation, and reduces histopathology after spinal cord injury in rats. — PubMed · 2015 · Journal Article
- Adoptive transfer of M2 macrophages promotes locomotor recovery in adult rats after spinal cord injury. — PubMed · 2015 · Journal Article
- Curcumin modulates TLR4/NF-κB inflammatory signaling pathway following traumatic spinal cord injury in rats. — PubMed · 2015 · Journal Article
- Nanocarrier-mediated inhibition of macrophage migration inhibitory factor attenuates secondary injury after spinal cord injury. — PubMed · 2015 · Journal Article
- Carvedilol promotes neurological function, reduces bone loss and attenuates cell damage after acute spinal cord injury in rats. — PubMed · 2015 · Journal Article
- Interleukin-33 treatment reduces secondary injury and improves functional recovery after contusion spinal cord injury. — PubMed · 2015 · Journal Article
- Resveratrol attenuates spinal cord injury-induced inflammatory damage in rat lungs. — PubMed · 2015 · Journal Article
- A Novel Nitronyl Nitroxide with Salicylic Acid Framework Attenuates Pain Hypersensitivity and Ectopic Neuronal Discharges in Radicular Low Back Pain. — PubMed · 2015 · Journal Article
- Dexamethasone reduces brain cell apoptosis and inhibits inflammatory response in rats with intracerebral hemorrhage. — PubMed · 2015 · Journal Article
- Rapamycin plays a neuroprotective effect after spinal cord injury via anti-inflammatory effects. — PubMed · 2015 · Journal Article
- Rosuvastatin attenuated the existing morphine tolerance in rats with L5 spinal nerve transection through inhibiting activation of astrocytes and phosphorylation of ERK42/44. — PubMed · 2015 · Journal Article
- Subdural infusion of dexamethasone inhibits leukomyelitis after acute spinal cord injury in a rat model. — PubMed · 2015 · Journal Article
- Chronic exposure to TGFβ1 regulates myeloid cell inflammatory response in an IRF7-dependent manner. — PubMed · 2014 · Journal Article
- Blockade of gap junction hemichannel protects secondary spinal cord injury from activated microglia-mediated glutamate exitoneurotoxicity. — PubMed · 2014 · Journal Article
- Hydrogen sulfide-releasing cyclooxygenase inhibitor ATB-346 enhances motor function and reduces cortical lesion volume following traumatic brain injury in mice. — PubMed · 2014 · Journal Article
- Decreased GFAP expression and improved functional recovery in contused spinal cord of rats following valproic acid therapy. — PubMed · 2014 · Journal Article
- Higenamine promotes M2 macrophage activation and reduces Hmgb1 production through HO-1 induction in a murine model of spinal cord injury. — PubMed · 2014 · Journal Article
- Mn porphyrin-based SOD mimic, MnTnHex-2-PyP(5+), and non-SOD mimic, MnTBAP(3-), suppressed rat spinal cord ischemia/reperfusion injury via NF-κB pathways. — PubMed · 2014 · Journal Article
- Curcumin improves the integrity of blood-spinal cord barrier after compressive spinal cord injury in rats. — PubMed · 2014 · Journal Article
- Glucocorticoid-induced leucine zipper (GILZ) controls inflammation and tissue damage after spinal cord injury. — PubMed · 2014 · Journal Article
- "Low-intensity laser therapy effect on the recovery of traumatic spinal cord injury". — PubMed · 2014 · Journal Article
- Beneficial effects of thymosin β4 on spinal cord injury in the rat. — PubMed · 2014 · Journal Article
- Idazoxan reduces blood-brain barrier damage during experimental autoimmune encephalomyelitis in mouse. — PubMed · 2014 · Journal Article
- Anti-inflammatory and anti-apoptotic effect of combined treatment with methylprednisolone and amniotic membrane mesenchymal stem cells after spinal cord injury in rats. — PubMed · 2014 · Journal Article
- Neuroprotection induced by N-acetylcysteine and selenium against traumatic brain injury-induced apoptosis and calcium entry in hippocampus of rat. — PubMed · 2014 · Journal Article
- Neurorestorative targets of dietary long-chain omega-3 fatty acids in neurological injury. — PubMed · 2014 · Journal Article
- Cytoprotective and anti-inflammatory effects of PAL31 overexpression in glial cells. — PubMed · 2014 · Journal Article
- Effects of methylprednisolone, dantrolene, and their combination on experimental spinal cord injury. — PubMed · 2014 · Journal Article
- Cytokine concentrations in the cerebrospinal fluid of great danes with cervical spondylomyelopathy. — PubMed · 2014 · Journal Article
- Immunohistochemical analysis of activin A expression in spinal cords of rats with clip compression injuries. — PubMed · 2014 · Journal Article
- Anti-inflammatory effects of curcumin in experimental spinal cord injury in rats. — PubMed · 2014 · Journal Article
- Inflammatory response to Escherichia coli urinary tract infection in the neurogenic bladder of the spinal cord injured host. — PubMed · 2014 · Journal Article
- Progesterone reduces secondary damage, preserves white matter, and improves locomotor outcome after spinal cord contusion. — PubMed · 2014 · Journal Article
- Two-photon-excited fluorescence microscopy as a tool to investigate the efficacy of methylprednisolone in a mouse spinal cord injury model. — PubMed · 2014 · Journal Article
- Curcumin inhibits the increase of labile zinc and the expression of inflammatory cytokines after traumatic spinal cord injury in rats. — PubMed · 2014 · Journal Article
- Neuroprotective effect of apigenin in rats after contusive spinal cord injury. — PubMed · 2014 · Journal Article
- Spontaneous regression of lumbar Hansen type 1 disk extrusion detected with magnetic resonance imaging in a dog. — PubMed · 2014 · Journal Article
- Toll-like receptor 2-mediated alternative activation of microglia is protective after spinal cord injury. — PubMed · 2014 · Journal Article
- Stem cell therapy and curcumin synergistically enhance recovery from spinal cord injury. — PubMed · 2014 · Journal Article
- Curcumin promotes the spinal cord repair via inhibition of glial scar formation and inflammation. — PubMed · 2014 · Journal Article
- Chronic ibuprofen administration reduces neuropathic pain but does not exert neuroprotection after spinal cord injury in adult rats. — PubMed · 2014 · Journal Article
- Effects of cilostazol on oxidative stress, systemic cytokine release, and spinal cord injury in a rat model of transient aortic occlusion. — PubMed · 2014 · Journal Article
- Mesenchymal stem cells improve locomotor recovery in traumatic spinal cord injury: systematic review with meta-analyses of rat models. — PubMed · 2014 · Journal Article
- Effects of montelukast and methylprednisolone on experimental spinal cord injury in rats. — PubMed · 2014 · Journal Article
- Ibuprofen protects ventilator-induced lung injury by downregulating Rho-kinase activity in rats. — PubMed · 2014 · Journal Article
- Systemic administration of atorvastatin improves locomotor functions and hyperacute-acute response after experimental spinal cord injury: an ultrastructural and biochemical analysis. — PubMed · 2014 · Journal Article
- The neuroprotective effect of treatment with curcumin in acute spinal cord injury: laboratory investigation. — PubMed · 2014 · Comparative Study
- A hydrogen sulfide-releasing cyclooxygenase inhibitor markedly accelerates recovery from experimental spinal cord injury. — PubMed · 2013 · Journal Article
- Do omega-3 polyunsaturated fatty acids ameliorate spinal cord injury?: Commentary on: Lim et al., Improved outcome after spinal cord compression injury in mice treated with docosahexaeonic acid. Exp. Neurol. Jan; 239:13-27. — PubMed · 2013 · Journal Article
- Substance P reduces apoptotic cell death possibly by modulating the immune response at the early stage after spinal cord injury. — PubMed · 2013 · Journal Article
- A re-assessment of the effects of treatment with a non-steroidal anti-inflammatory (ibuprofen) on promoting axon regeneration via RhoA inhibition after spinal cord injury. — PubMed · 2013 · Journal Article
- Genetically modified mesenchymal stem cells (MSCs) promote axonal regeneration and prevent hypersensitivity after spinal cord injury. — PubMed · 2013 · Journal Article
- Tempol reduces injury area in rat model of spinal cord contusion injury through suppression of iNOS and COX-2 expression. — PubMed · 2013 · Journal Article
- Temporal changes in monocyte and macrophage subsets and microglial macrophages following spinal cord injury in the Lys-Egfp-ki mouse model. — PubMed · 2013 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-09-29 Collection window: 2026-09-16 – 2026-09-29 | matched in this collection walk 0 · accumulated records across collection walks 13 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1741999 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 17 · accumulated records across collection walks 2063 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("immunomodulation" OR "anti-inflammatory") - Crossref
spinal cord injury immunomodulation anti-inflammatory - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Immunomodulating Agents"[MeSH Terms] OR "Anti-Inflammatory Agents"[MeSH Terms] OR "immunomodulation"[Title/Abstract] OR "anti-inflammatory"[Title/Abstract])