A subject this map covers
Immunomodulatory drugs
Part of: Inflammation and immune response
What belongs here
Drugs that change the immune response after injury, other than steroids and minocycline, which have their own concepts.
What does not belong here, however close it looks
Immunosuppression to keep a graft alive is part of cell therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 678 records · 1968–2026
- Indexed as work in animals: 932 records · 1982–2026
- Indexed as laboratory work: 34 records · 1991–2026
- The source has not said who or what was studied: 437 records · 1977–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
2081 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Pregabalin as a neuroprotector after spinal cord injury in rats. — PubMed · 2008 · Journal Article
- Effects of activated protein C on neonatal hypoxic ischemic brain injury. — PubMed · 2008 · Journal Article
- Detrimental effects of antiapoptotic treatments in spinal cord injury. — PubMed · 2008 · Journal Article
- Spatial distribution and acute anti-inflammatory effects of Methylprednisolone after sustained local delivery to the contused spinal cord. — PubMed · 2008 · Journal Article
- Methylprednisolone protects oligodendrocytes but not neurons after spinal cord injury. — PubMed · 2008 · Journal Article
- Limited minocycline neuroprotection after balloon-compression spinal cord injury in the rat. — PubMed · 2008 · Journal Article
- Effect of 17beta-estradiol on signal transduction pathways and secondary damage in experimental spinal cord trauma. — PubMed · 2008 · Journal Article
- The protective effects of 15-deoxy-delta-(12,14)-prostaglandin J2 in spinal cord injury. — PubMed · 2008 · Journal Article
- Neuroprotective effects of ketorolac tromethamine after spinal cord injury in rats: an ultrastructural study. — PubMed · 2008 · Journal Article
- Bioavailability effect of methylprednisolone by polymeric micelles. — PubMed · 2008 · Journal Article
- Selenium attenuates ROS-mediated apoptotic cell death of injured spinal cord through prevention of mitochondria dysfunction; in vitro and in vivo study. — PubMed · 2008 · Journal Article
- TNF-alpha blockage in a mouse model of SCI: evidence for improved outcome. — PubMed · 2008 · Journal Article
- Combination of dexamethasone and etanercept reduces secondary damage in experimental spinal cord trauma. — PubMed · 2007 · Journal Article
- Increase of annexin 1 immunoreactivity in spinal cord of newborn opossum (Monodelphis domestica) at the time when regeneration after injury stops being possible. — PubMed · 2007 · Journal Article
- Annexin A1 reduces inflammatory reaction and tissue damage through inhibition of phospholipase A2 activation in adult rats following spinal cord injury. — PubMed · 2007 · Journal Article
- LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis. — PubMed · 2007 · Journal Article
- Acute spinal cord injury changes the disposition of some, but not all drugs given intravenously. — PubMed · 2007 · Journal Article
- Effects of combination of melatonin and dexamethasone on secondary injury in an experimental mice model of spinal cord trauma. — PubMed · 2007 · Journal Article
- Confirmed and presumptive cervical vertebral compressive myelopathy in older horses: a retrospective study (1992-2004). — PubMed · 2007 · Journal Article
- Nonsteroidal anti-inflammatory drugs promote axon regeneration via RhoA inhibition. — PubMed · 2007 · Comparative Study
- [Efficiency of coenzyme Q(10) at experimental spinal cord injury]. — PubMed · 2007 · English Abstract
- Protective effect of intrathecal ketorolac in spinal cord ischemia in rats: a microdialysis study. — PubMed · 2007 · Journal Article
- Activation of sensory neurons contributes to reduce spinal cord injury in rats. — PubMed · 2007 · Journal Article
- Metoprolol treatment decreases tissue myeloperoxidase activity after spinal cord injury in rats. — PubMed · 2007 · Comparative Study
- Role of prostacyclin in the development of compression trauma-induced spinal cord injury in rats. — PubMed · 2006 · Journal Article
- Effects of a novel tripeptide on neurological outcomes after spinal cord injury. — PubMed · 2006 · Journal Article
- [Gene expression profile in acute spinal cord injury screened by cDNA microarray: experiment with rats]. — PubMed · 2006 · English Abstract
- Estrogen reduces the severity of autonomic dysfunction in spinal cord-injured male mice. — PubMed · 2006 · Comparative Study
- Comparative analysis of cytokine gene expression in cerebrospinal fluid of horses without neurologic signs or with selected neurologic disorders. — PubMed · 2006 · Comparative Study
- The tripeptide phenylalanine-(D) glutamate-(D) glycine modulates leukocyte infiltration and oxidative damage in rat injured spinal cord. — PubMed · 2006 · Journal Article
- NON-activated protein C as post-treatment after spinal cord compression injury in rats. — PubMed · 2006 · Journal Article
- Minocycline neuroprotects, reduces microgliosis, and inhibits caspase protease expression early after spinal cord injury. — PubMed · 2006 · Journal Article
- Effects of COX-2 and iNOS inhibitors alone or in combination with olfactory ensheathing cell grafts after spinal cord injury. — PubMed · 2006 · Journal Article
- Delayed transplantation of adult neural precursor cells promotes remyelination and functional neurological recovery after spinal cord injury. — PubMed · 2006 · Journal Article
- Immunomodulatory effects of etanercept in an experimental model of spinal cord injury. — PubMed · 2006 · Journal Article
- Neuroprotective effects of Nigella sativa on experimental spinal cord injury in rats. — PubMed · 2006 · Journal Article
- Suitability of allogeneic sertoli cells for ex vivo gene delivery in the injured spinal cord. — PubMed · 2006 · Comparative Study
- Effect of betamethasone on neuropathic pain and cerebral expression of NF-kappaB and cytokines. — PubMed · 2006 · Comparative Study
- A comparison of adenosine A2A agonism and methylprednisolone in attenuating neuronal damage and improving functional outcome after experimental traumatic spinal cord injury in rabbits. — PubMed · 2006 · Journal Article
- Methylprednisolone causes minimal improvement after spinal cord injury in rats, contrasting with benefits of an anti-integrin treatment. — PubMed · 2005 · Comparative Study
- The nitrosteroid NCX 1015, a prednisolone derivative, improves recovery of function in rats after spinal cord injury. — PubMed · 2005 · Comparative Study
- Dose-dependent neuroprotective effects of melatonin on experimental spinal cord injury in rats. — PubMed · 2005 · Comparative Study
- FK 506 reduces tissue damage and prevents functional deficit after spinal cord injury in the rat. — PubMed · 2005 · Journal Article
- Comparison of effects of methylprednisolone and anti-CD11d antibody treatments on autonomic dysreflexia after spinal cord injury. — PubMed · 2005 · Comparative Study
- Using methylprednisolone to supplement direct current electrical field in promoting spinal-cord regeneration. — PubMed · 2005 · Journal Article
- Intrathecal ketorolac pretreatment reduced spinal cord ischemic injury in rats. — PubMed · 2005 · Journal Article
- Methylprednisolone inhibits production of interleukin-1beta and interleukin-6 in the spinal cord following compression injury in rats. — PubMed · 2005 · Journal Article
- Neuroprotective effects of ebselen on experimental spinal cord injury in rats. — PubMed · 2005 · Journal Article
- Effects of methylprednisolone on the neural conduction of the motor evoked potentials in spinal cord injured rats. — PubMed · 2005 · Journal Article
- Anti-CD11d integrin antibody treatment restores normal serotonergic projections to the dorsal, intermediate, and ventral horns of the injured spinal cord. — PubMed · 2005 · Journal Article
- Antithrombin reduces compression-induced spinal cord injury in rats. — PubMed · 2004 · Journal Article
- Vaccinia virus complement control protein reduces inflammation and improves spinal cord integrity following spinal cord injury. — PubMed · 2004 · Comparative Study
- Induction of cyclooxygenase-2 in reactive glial cells by the CD40 pathway: relevance to amyotrophic lateral sclerosis. — PubMed · 2004 · Journal Article
- AIT-082 and methylprednisolone singly, but not in combination, enhance functional and histological improvement after acute spinal cord injury in rats. — PubMed · 2004 · Journal Article
- Lesional RhoA+ cell numbers are suppressed by anti-inflammatory, cyclooxygenase-inhibiting treatment following subacute spinal cord injury. — PubMed · 2004 · Journal Article
- Intrathecal ketorolac in dogs and rats. — PubMed · 2004 · Journal Article
- Potent pro-inflammatory actions of leukemia inhibitory factor in the spinal cord of the adult mouse. — PubMed · 2004 · Journal Article
- Upregulation of annexins I, II, and V after traumatic spinal cord injury in adult rats. — PubMed · 2004 · Comparative Study
- Local acute application of BDNF in the lesioned spinal cord anti-inflammatory and anti-oxidant effects. — PubMed · 2004 · Journal Article
- Screening anti-inflammatory compounds in injured spinal cord with microarrays: a comparison of bioinformatics analysis approaches. — PubMed · 2004 · Comparative Study
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-09-29 Collection window: 2026-09-16 – 2026-09-29 | matched in this collection walk 0 · accumulated records across collection walks 13 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1741999 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 17 · accumulated records across collection walks 2063 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("immunomodulation" OR "anti-inflammatory") - Crossref
spinal cord injury immunomodulation anti-inflammatory - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Immunomodulating Agents"[MeSH Terms] OR "Anti-Inflammatory Agents"[MeSH Terms] OR "immunomodulation"[Title/Abstract] OR "anti-inflammatory"[Title/Abstract])