A subject this map covers
Immunomodulatory drugs
Part of: Inflammation and immune response
What belongs here
Drugs that change the immune response after injury, other than steroids and minocycline, which have their own concepts.
What does not belong here, however close it looks
Immunosuppression to keep a graft alive is part of cell therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 678 records · 1968–2026
- Indexed as work in animals: 932 records · 1982–2026
- Indexed as laboratory work: 34 records · 1991–2026
- The source has not said who or what was studied: 437 records · 1977–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
2081 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Early anti-inflammatory treatment reduces lipid peroxidation and protein nitration after spinal cord injury in rats. — PubMed · 2004 · Journal Article
- The effects of endogenous interleukin-10 on gray matter damage and the development of pain behaviors following excitotoxic spinal cord injury in the mouse. — PubMed · 2004 · Journal Article
- The effects of treatment with antibodies to transforming growth factor beta1 and beta2 following spinal cord damage in the adult rat. — PubMed · 2004 · Journal Article
- Minocycline reduces cell death and improves functional recovery after traumatic spinal cord injury in the rat. — PubMed · 2003 · Comparative Study
- Spinal blood flow in 24-hour megadose glucocorticoid treatment in awake pigs. — PubMed · 2003 · Journal Article
- Effects of corticosteroid and electroacupuncture on experimental spinal cord injury in dogs. — PubMed · 2003 · Clinical Trial
- Differential antinociceptive effects induced by a selective cyclooxygenase-2 inhibitor (SC-236) on dorsal horn neurons and spinal withdrawal reflexes in anesthetized spinal rats. — PubMed · 2003 · Comparative Study
- Evaluation of time-dependent spread of tissue damage in experimental spinal cord injury by killed-end evoked potential: effect of high-dose methylprednisolone. — PubMed · 2003 · Journal Article
- Efficacy of methylprednisolone in acute experimental cauda equina injury. — PubMed · 2002 · Journal Article
- Histologic characterization of acute spinal cord injury treated with intravenous methylprednisolone. — PubMed · 2002 · Journal Article
- Assessment of spinal cord pathology following trauma using early changes in the spinal cord evoked potentials: a pharmacological and morphological study in the rat. — PubMed · 2002 · Journal Article
- Selective cyclooxygenase 2 inhibition lowers spinal cord prostaglandin concentrations after injury. — PubMed · 2001 · Journal Article
- Methylprednisolone reduces spinal cord injury in rats without affecting tumor necrosis factor-alpha production. — PubMed · 2001 · Journal Article
- Reduction of pathological and behavioral deficits following spinal cord contusion injury with the selective cyclooxygenase-2 inhibitor NS-398. — PubMed · 2001 · Journal Article
- CM101 stimulates cutaneous wound healing through an anti-angiogenic mechanism. — PubMed · 2001 · Journal Article
- Inhibition of monocyte/macrophage migration to a spinal cord injury site by an antibody to the integrin alphaD: a potential new anti-inflammatory treatment. — PubMed · 2000 · Journal Article
- Persistent accumulation of cyclooxygenase-1 (COX-1) expressing microglia/macrophages and upregulation by endothelium following spinal cord injury. — PubMed · 2000 · Journal Article
- Vasoactive intestinal peptide and pituitary adenylyl cyclase-activating polypeptide inhibit tumor necrosis factor-alpha production in injured spinal cord and in activated microglia via a cAMP-dependent pathway. — PubMed · 2000 · Journal Article
- Glucocorticoid receptor expression in the spinal cord after traumatic injury in adult rats. — PubMed · 1999 · Journal Article
- Bioavailability of diclofenac after intramuscular administration to rats with experimental spinal cord injury. — PubMed · 1999 · Journal Article
- Effect of experimental spinal cord injury on salicylate bioavailability after oral aspirin administration. — PubMed · 1999 · Journal Article
- Is indomethacin harmful in spinal cord injury treatment? An experimental study. — PubMed · 1999 · Journal Article
- Current concepts in the management of acute spinal cord injury. — PubMed · 1999 · Journal Article
- Spinal cord injury in small animals 2. Current and future options for therapy. — PubMed · 1999 · Comment
- Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury. — PubMed · 1999 · Journal Article
- An imposed oscillating electrical field improves the recovery of function in neurologically complete paraplegic dogs. — PubMed · 1999 · Clinical Trial
- Cyclosporin-A inhibits lipid peroxidation after spinal cord injury in rats. — PubMed · 1999 · Journal Article
- The unique histopathological responses of the injured spinal cord. Implications for neuroprotective therapy. — PubMed · 1999 · Journal Article
- Role of cyclooxygenase 2 in acute spinal cord injury. — PubMed · 1998 · Journal Article
- [Experimental study on the efficacy of methyl prednisolone in the treatment of traction injury of spinal cord in rabbits]. — PubMed · 1998 · English Abstract
- Methylprednisolone inhibition of TNF-alpha expression and NF-kB activation after spinal cord injury in rats. — PubMed · 1998 · Journal Article
- Estrogens attenuate neuronal injury due to hemoglobin, chemical hypoxia, and excitatory amino acids in murine cortical cultures. — PubMed · 1997 · Journal Article
- Effects of pro-inflammatory cytokines in experimental spinal cord injury. — PubMed · 1997 · Journal Article
- Effect of a single huge dose of methylprednisolone on blood flow, evoked potentials, and histology after acute spinal cord injury in the rat. — PubMed · 1997 · Journal Article
- Effect of intra-arachnoid space perfusion on thromboxane A and prostacycline in experimental spinal cord injury. — PubMed · 1997 · Journal Article
- Experimental analysis of progressive necrosis after spinal cord trauma in the rat: etiological role of the inflammatory response. — PubMed · 1997 · Journal Article
- Prostaglandins modulate constitutive isoform of heat shock protein (72 kD) response following trauma to the rat spinal cord. — PubMed · 1997 · Journal Article
- The effects of taxol, methylprednisolone, and 4-aminopyridine in compressive spinal cord injury: a qualitative experimental study. — PubMed · 1996 · Clinical Trial
- A possible central antinociceptive effect of dipyrone in mice. — PubMed · 1996 · Journal Article
- Changes in phospholipids and acetylcholinesterase during early phase of injury to spinal cord--an experimental study in rats. — PubMed · 1996 · Journal Article
- Effects of exogenous transforming growth factor-beta 1 on spinal cord injury in rats. — PubMed · 1996 · Journal Article
- The effects of methylprednisolone and the ganglioside GM1 on acute spinal cord injury in rats. — PubMed · 1994 · Journal Article
- Spinal trauma. Pathophysiology and management of traumatic spinal injuries. — PubMed · 1992 · Journal Article
- Neuropathologic and therapeutic studies in experimental spinal cord trauma. — PubMed · 1991 · Comparative Study
- Participation of serotonergic mechanisms in the pathophysiology of experimental neoplastic spinal cord compression. — PubMed · 1991 · Journal Article
- Experimental neoplastic spinal cord compression: effect of anti-inflammatory agents and glutamate receptor antagonists on vascular permeability. — PubMed · 1990 · Journal Article
- Problems and complications associated with the nonsurgical management of intervertebral disc disease. — PubMed · 1989 · Journal Article
- Comparison of soluble dexamethasone sodium phosphate with free dexamethasone and indomethacin in treatment of experimental neoplastic spinal cord compression. — PubMed · 1988 · Comparative Study
- Prevention of damage in acute spinal cord injury by peptides and pharmacologic agents. — PubMed · 1982 · Journal Article
- Effects of antacids, cimetidine, and 16,16-dimethyl prostaglandin E2 on acute gastric erosions in a spinal rat. — PubMed · 1982 · Comparative Study
Indexed as laboratory work
- A Polydopamine-coated Engineered Type II Collagen Scaffold for Motor Neuron Organization and Spinal Cord Injury Regeneration. — PubMed · 2026 · Journal Article
- Research Progress on Biomaterial Scaffolds Carrying Stem Cells for Inflammation Regulation After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Engineering a multilayered thin-film agarose-based hydrogel to support adipose-derived stromal vascular fraction therapy in spinal cord injury. — PubMed · 2026 · Journal Article
- The Dual Role of Gastrodin in Spinal Cord Injury: Microglial Phenotype Switching and Neuronal Survival via PI3K/AKT Activation. — PubMed · 2026 · Journal Article
- Enhanced spinal cord injury repair by nerve extracellular matrix/carboxymethyl chitosan /oxidized alginate hydrogel containing OE-MSCs. — PubMed · 2026 · Journal Article
- Regenerative Potential of Neural Stem/Progenitor Cells for Bone Repair. — PubMed · 2025 · Journal Article
- Characterization of three washing/decellularization procedures for the production of bioactive human micronized neural tissue (hMINT). — PubMed · 2023 · Journal Article
- Human dental pulp stem cell monolayer and spheroid therapy after spinal motor root avulsion in adult rats. — PubMed · 2023 · Journal Article
- Multifunctional Integrated Nanozymes Facilitate Spinal Cord Regeneration by Remodeling the Extrinsic Neural Environment. — PubMed · 2023 · Journal Article
- Anti-Inflammatory Effects of Encapsulated Human Mesenchymal Stromal/Stem Cells and a Method to Scale-Up Cell Encapsulation. — PubMed · 2022 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-09-29 Collection window: 2026-09-16 – 2026-09-29 | matched in this collection walk 0 · accumulated records across collection walks 13 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1741999 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 17 · accumulated records across collection walks 2063 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("immunomodulation" OR "anti-inflammatory") - Crossref
spinal cord injury immunomodulation anti-inflammatory - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Immunomodulating Agents"[MeSH Terms] OR "Anti-Inflammatory Agents"[MeSH Terms] OR "immunomodulation"[Title/Abstract] OR "anti-inflammatory"[Title/Abstract])