A subject this map covers
Immunomodulatory drugs
Part of: Inflammation and immune response
What belongs here
Drugs that change the immune response after injury, other than steroids and minocycline, which have their own concepts.
What does not belong here, however close it looks
Immunosuppression to keep a graft alive is part of cell therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 678 records · 1968–2026
- Indexed as work in animals: 932 records · 1982–2026
- Indexed as laboratory work: 34 records · 1991–2026
- The source has not said who or what was studied: 437 records · 1977–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
2081 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
The source has not said who or what was studied
- Machine learning identifies key cells and therapeutic targets during ferroptosis after spinal cord injury. — PubMed · 2026 · Journal Article
- Atractylenolide III for central nervous system disorders: a review of multi-target mechanisms and therapeutic potential. — PubMed · 2026 · Journal Article
- Sulforaphane enhances locomotor recovery after spinal cord injury through antioxidant, anti-inflammatory, and JAK/STAT-modulating mechanisms. — PubMed · 2026 · Journal Article
- Diselenide-bridged mesoporous silica nanoplatform for baicalin delivery facilitates spinal cord injury repair via CHCHD2-mediated mitochondrial homeostasis restoration. — PubMed · 2026 · Journal Article
- Immunomodulatory Mechanisms of Mesenchymal Stromal Cells: Cytokine Networks and Therapeutic Potential Across Immune-Mediated, Inflammatory, and Regenerative Disorders. — PubMed · 2026 · Journal Article
- Neuroprotective Effects of Moringa Peregrina Leaf Alcoholic Extract on Compression Model of Spinal Cord Injury in Rats. — PubMed · 2026 · Journal Article
- Targeting microglial PANoptosis through AMPK activation: Metformin as a promising therapy for spinal cord injury. — PubMed · 2026 · Journal Article
- A sequential multimodal framework for spinal cord regeneration. — PubMed · 2026 · Journal Article
- The SHEDs-derived apoptotic bodies for inflammatory regulation in spinal cord repair. — PubMed · 2026 · Journal Article
- Dihydromyricetin exerts neuroprotective effects in acute spinal cord injury by inhibiting NLRP3/Caspase-1 inflammasome through gut microbiome modeling. — PubMed · 2026 · Journal Article
- ROS-responsive hydrogels functionalized with Cu/Zn MOF targeting oxidative stress mitigation and inflammation modulation to promote spinal cord injury repair. — PubMed · 2026 · Journal Article
- Neuroinflammation in Spinal Cord Injury: Cellular and Molecular Mechanisms. — PubMed · 2026 · Journal Article
- Trichosanthis peel injection improves functional recovery after spinal cord injury associated with the modulation of neuroinflammation and oxidative stress. — PubMed · 2026 · Journal Article
- Spatiotemporal liposome-zwitterionic nano-hydrogel orchestrates immunomodulation and neurogenesis in spinal cord injury repair. — PubMed · 2026 · Journal Article
- Intervention of Rutin and Ochnaflavone in the Attenuation of Neuroinflammation and Neuronal Apoptosis in Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Polydatin for treating spinal cord injury: Multiple mechanisms and challenges. — PubMed · 2026 · Journal Article
- The Emerging Role of N-Lactoyl-Phenylalanine (Lac-Phe) in Metabolic Regulation and Disease: From Exercise-Induced Metabolite to Therapeutic Candidate. — PubMed · 2026 · Journal Article
- Exosome-derived ncRNAs and proteins: inflammation regulatory mechanisms and biomarker potential in spinal cord injury. — PubMed · 2026 · Journal Article
- The Correct Nutritional Intake in the Prevention and Treatment of Skin Lesions in Patients With Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Efficacy of Minocycline in Acute Traumatic Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Garcinol Promotes Recovery After Spinal Cord Injury in Mouse by Modulating Microglial Polarization Through EGFR/PI3K/AKT Signaling. — PubMed · 2026 · Journal Article
- Systemic delivery of drug-free polymeric nanoparticles reprograms innate immunity in a sex-dependent manner after spinal cord injury. — PubMed · 2026 · Journal Article
- 3D bioprinted multifunctional GelMA/TMP scaffold integrated with neural stem cell-derived extracellular vesicles and neural progenitor cells for spinal cord injury repair. — PubMed · 2026 · Journal Article
- Spinal cord injury and inflammatory mediators: Role in "fire barrier" formation and potential for neural regeneration. — PubMed · 2026 · Journal Article
- Mesenchymal stem cells and the central nervous system: historical perspectives and future directions. — PubMed · 2026 · Journal Article
- Neuroprotection or Neurotoxicity? Insights from preclinical and clinical studies of methotrexate in spinal cord injury. — PubMed · 2026 · Journal Article
- The role of short-chain fatty acids in spinal cord injury: A systematic review of human and animal evidence. — PubMed · 2026 · Journal Article
- A bioinspired anisotropic anti-inflammatory scaffold enhances spinal nerve regeneration and neural circuit reconstruction via FGF13/Ca(2+)/CaMK2A/CREB pathway. — PubMed · 2026 · Journal Article
- Can Transcutaneous Vagus Nerve Stimulation be Effective After Rats' Spinal Cord Injury? — PubMed · 2026 · Journal Article
- Pterostilbene Promotes Spinal Cord Injury Recovery by Inhibiting Ferroptosis via Keap1/Nrf2/SLC7A11/GPX4 Axis Activation. — PubMed · 2026 · Journal Article
- Differential microglial dynamics and neuroinflammation underlying neuropathic pain in the central nervous system: comparative insights from spinal cord injury and compressive myelopathy models. — PubMed · 2026 · Journal Article
- A multifunctional and ROS response CO-gas delivery platform for spinal cord regeneration. — PubMed · 2026 · Journal Article
- Intelligent structure prediction and visualization analysis Aof macrophage-mediated immunomodulation in spinal cord injury repair research — Crossref · 2026 · journal-article
- Microglia overexpressing brain-derived neurotrophic factor promote vascular repair and functional recovery in mice after spinal cord injury. — PubMed · 2026 · Journal Article
- Insights into Astrogliosis, Inflammation Processes, and Emerging Treatments by Exosome Therapy and Low-Level Laser Therapy for Spinal Cord Injury: A Systematic Review. — PubMed · 2025 · Journal Article
- Therapeutic potential of stem cells in pediatric neurology: Insights from clinical trials. — PubMed · 2025 · Journal Article
- Dynamic development of microglia and macrophages after spinal cord injury. — PubMed · 2025 · Journal Article
- Engineering a targeted daphnetin delivery system to enhance spinal cord injury treatment effectiveness. — PubMed · 2025 · Journal Article
- Early intervention with extracellular vesicles derived from human umbilical cord mesenchymal stem cells enhances survival and functional recovery after spinal cord injury in rats. — PubMed · 2025 · Journal Article
- Therapeutic potential of melatonin in musculoskeletal medicine. — PubMed · 2025 · Journal Article
- Pharmacological targeting cGAS/STING/NF-κB axis by tryptanthrin induces microglia polarization toward M2 phenotype and promotes functional recovery in a mouse model of spinal cord injury. — PubMed · 2025 · Journal Article
- Immunomodulatory Biomaterials for Bone and Soft Tissue Chronic Inflammation Diseases. — PubMed · 2025 · Journal Article
- Biomimetic membrane-coating zinc sulfide nanoparticles for anti-inflammatory combined neuroprotective therapy for spinal cord injury. — PubMed · 2025 · Journal Article
- Implications of the gut microbiome in spinal cord injuries. — PubMed · 2025 · Journal Article
- Mapping the Landscape of Mesenchymal Stem Cell-Derived Extracellular Vesicles: From Bench to Bedside. — PubMed · 2025 · Journal Article
- Below the Belt: Risk Factors for Urologic Adverse Events After Central Cord Syndrome. — PubMed · 2025 · Journal Article
- Apigenin Suppresses NLRP3 Inflammasome Activation and Pyroptosis and Promotes Functional Recovery by Promoting Mitophagy in Experimental Spinal Cord Injured Rats. — PubMed · 2025 · Journal Article
- Exoskeleton Robot Gait Training and Its Impact on the Gut Microbiota-Brain Axis in Incomplete Spinal Cord Injury Patients: A Narrative Review of Rehabilitation Mechanisms. — PubMed · 2025 · Journal Article
- Electroacupuncture at Huatuo-Jiaji acupoints combined with conductive hydrogel synergistically improves bladder and motor functions after spinal cord injury. — PubMed · 2025 · Journal Article
- Sustained-Release Spermidine Hydrogel Inhibits M1 Macrophage Polarization and Promotes Tissue Repair for Spinal Cord Injury Repair. — PubMed · 2025 · Journal Article
- Nfkbia-driven neuroinflammatory pathways mediate depression following spinal cord injury. — PubMed · 2025 · Journal Article
- Intrathecal silymarin administration improves recovery after compression spinal cord injury: evidence for neuroprotection, antioxidant, and anti-inflammatory action. — PubMed · 2025 · Journal Article
- Intravenously injected poly(amino acid) nanoformulation relieves spinal cord injury through synergistical modulation of microenvironments. — PubMed · 2025 · Journal Article
- Boosting the Therapeutic Potential of Extracellular Vesicles Derived From Mesenchymal Stem Cells via Advanced Preconditioning for Neurodegenerative Disorders. — PubMed · 2025 · Journal Article
- Current Mechanobiological Pathways and Therapies Driving Spinal Health. — PubMed · 2025 · Journal Article
- Cryogel scaffolds for localised delivery of lipopolysaccharide in organotypic spinal cord slice cultures: A novel ex vivo model of neuroinflammation. — PubMed · 2025 · Journal Article
- Low-Frequency (1 Hz) Repetitive Trans-Spinal Magnetic Stimulation Attenuates NLRP3-Driven Neuroinflammation and Enhances Motor Recovery in Spinal Cord-Injured Mice. — PubMed · 2025 · Journal Article
- Localised delivery of interleukin-13 from a PLGA microparticle embedded GelMA hydrogel improves functional and histopathological recovery in a mouse contusion spinal cord injury model. — PubMed · 2025 · Journal Article
- Functional Recovery Promotion After Spinal Cord Injury With Astaxanthin Treatment in Preclinical Studies: A Systematic Review and Meta-Analysis. — PubMed · 2025 · Journal Article
- Successful Treatment of Functional Neurologic Symptom Disorder (Conversion Disorder) With Subdissociative Dose Ketamine in the Emergency Department. — PubMed · 2025 · Case Reports
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-09-29 Collection window: 2026-09-16 – 2026-09-29 | matched in this collection walk 0 · accumulated records across collection walks 13 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1741999 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 17 · accumulated records across collection walks 2063 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("immunomodulation" OR "anti-inflammatory") - Crossref
spinal cord injury immunomodulation anti-inflammatory - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Immunomodulating Agents"[MeSH Terms] OR "Anti-Inflammatory Agents"[MeSH Terms] OR "immunomodulation"[Title/Abstract] OR "anti-inflammatory"[Title/Abstract])