A subject this map covers
Macrophage therapy and polarisation
Part of: Inflammation and immune response
What belongs here
Delivering or reprogramming macrophages to change the character of inflammation at the injury.
What does not belong here, however close it looks
Describing what macrophages do without intervening is mechanism, not therapy; such a record stays in the parent concept.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 265 records · 1967–2026
- Indexed as work in animals: 781 records · 1966–2026
- Indexed as laboratory work: 41 records · 1988–2026
- The source has not said who or what was studied: 211 records · 1999–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1298 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Morusin Alleviates Spinal Cord Injury in Rats by Regulating Macrophage Reprogramming Through Targeting RELA and NRF2. — PubMed · 2026 · Journal Article
- Naringenin alleviates spinal cord injury by ameliorating macrophage/microglia autophagy via progranulin stabilisation. — PubMed · 2026 · Journal Article
- TREM2 Facilitates Myelin Debris Clearance but Exacerbates Chronic Inflammation and Fibrosis After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Clec7a-targeted Res@GelMA hydrogels regulate macrophage polarization to reduce neuroinflammation and promote spinal cord repair. — PubMed · 2026 · Journal Article
- Modulation of inflammatory and regenerative responses by Galectin-3 after spinal cord injury in wild-type and Galectin-3 knockout mice. — PubMed · 2026 · Journal Article
- Dual-engineered Treg-Exosome-IKVAV nanovesicles spatiotemporally sequentially regulate neuro-immune microenvironment to promote spinal cord injury repair. — PubMed · 2026 · Journal Article
- Multimodal electroconductive PLGA-based scaffold orchestrates neuroprotection and regeneration following severe spinal cord injury. — PubMed · 2026 · Journal Article
- Biomimetic core-shell GelMA microspheres co-delivering ANXA1, NGF, and fibronectin enable phase-matched immunomodulation and neurorepair after spinal cord injury. — PubMed · 2026 · Journal Article
- Molecular Changes in CSPG and Glial Scar Markers in Response to Subpial Chondroitinase ABC Treatment Following Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Olfactory ensheathing cell transplantation targets macrophage extracellular traps and NKCC1 to alleviate pain after spinal cord injury. — PubMed · 2026 · Journal Article
- Targeting RXRα inhibits foamy macrophage formation and neuroinflammation by promoting cholesterol efflux channels post traumatic spinal cord injury. — PubMed · 2026 · Journal Article
- Conductive hydrogel combined with electrical stimulation remodels the microenvironment for nerve regeneration to promote spinal cord injury repair. — PubMed · 2025 · Journal Article
- Photobiomodulation Reduces Fibrous Scar Formation After Spinal Cord Injury by Downregulating CXCL3 Expression in Macrophages. — PubMed · 2025 · Journal Article
- Lipid accumulation in foam cells drives C1q-dependent synaptic loss and impairs motor function recovery after spinal cord injury. — PubMed · 2025 · Journal Article
- Engineered lesion-homing liposomes encapsulating Rosuvastatin enhance spinal cord injury repair by preventing the formation of foamy macrophages. — PubMed · 2025 · Journal Article
- Farrerol confers neuroprotection in spinal cord injury by regulating macrophages/microglia polarization through the JAK2/STAT3 pathway. — PubMed · 2025 · Journal Article
- Integrating sensitive motor tasks with histopathology detects sex differences in recovery after spinal cord injury. — PubMed · 2025 · Journal Article
- D-Dopachrome Tautomerase-Driven Astrocytic CCL7 Aggravates Neuropathology by Recruitment of Microglia Following Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Cellular Distribution of Pyruvate Kinase M2 After Spinal Cord Injury in Adult Rats. — PubMed · 2025 · Journal Article
- Mogroside V Ameliorates Spinal Cord Injury by Inhibiting M1 Microglia Polarization. — PubMed · 2025 · Journal Article
- CD200R1 modulates myelin phagocytosis and spleen response following spinal cord injury. — PubMed · 2025 · Journal Article
- Function of orthologous fibroblast growth factor 11 protein in angiogenesis and immunomodulatory after spinal cord injury. — PubMed · 2025 · Journal Article
- Hyperoside alleviates macrophages and microglia-mediated neuroinflammation and oxidative stress through activating PI3K/AKT and Nrf2/HO-1 signaling pathway post spinal cord injury. — PubMed · 2025 · Journal Article
- PD-1/PD-L1 inhibits M1 polarization of microglia and macrophages through STAT1/NF-κB and Akt/mTOR signaling pathways. — PubMed · 2025 · Journal Article
- Regulating PPARG Reduces Lipid Accumulation in Microglia and Promotes Functional Recovery After Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Dental pulp stem cells promote the recovery of spinal cord injury by regulating microglia polarization via JAK2/STAT3 signaling pathway. — PubMed · 2025 · Journal Article
- GDF11 alleviates spinal cord injury in rats by modulating microglia polarization through Smad2/3 and MAPK/NFκB signaling pathways. — PubMed · 2025 · Journal Article
- From Molecular Docking to Rat Models: Butyrate From a High-Fiber Diet Inhibits HDAC1 and NLRP3 Inflammasome to Alleviate Oxidative Stress and Inflammation After Spinal Cord Injury. — PubMed · 2025 · Journal Article
- GLP-1R activation restores Gas6-driven efferocytosis in senescent foamy macrophages to promote neural repair. — PubMed · 2025 · Journal Article
- Long-term dynamics of the spinal cord injury neuroinflammatory response and sensory dysfunction in female mice. — PubMed · 2025 · Journal Article
- Piezo1 deletion ameliorates inflammation and functional recovery in spinal cord injury through altering microglia/macrophage phenotype. — PubMed · 2025 · Journal Article
- A Myelin Debris Cleaner for Spinal Cord Injury Recovery: Polycaprolactone / Cell Membrane Assembled Scaffolds. — PubMed · 2025 · Journal Article
- Hypoxia-Inducible Factor-1α-Induced Astrocytic D-Dopachrome Tautomerase Activates Microglial Inflammatory Response following Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Nasal Delivery of Engineered Exosomes via a Thermo-Sensitive Hydrogel Depot Reprograms Glial Cells for Spinal Cord Repair. — PubMed · 2025 · Journal Article
- Phase-adapted metal ion supply for spinal cord repair with a Mg-Zn incorporated chimeric microsphere. — PubMed · 2025 · Journal Article
- Single-Cell Sequencing-Based Exploration of the Role of Tip Cells on Astrocytes and Macrophages After Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Enhanced locomotor recovery in mice lacking GlcNAc6ST1 and GlcNAc6ST4 following spinal cord injury. — PubMed · 2025 · Journal Article
- Identification of Ifitm1 as a Pivotal Gene in Mouse Spinal Cord Injury Using Comprehensive Machine Learning Algorithms. — PubMed · 2025 · Journal Article
- Magnetically Driven Biomimetic Microrobot Loaded with Eleutheroside B for Targeted Delivery and Neural Repair in Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Imatinib prevents blood-spinal cord barrier disruption by inhibiting PDGFR-mediated JMJD3 expression and activation after spinal cord injury. — PubMed · 2025 · Journal Article
- A Zinc-Citrate Metal-Organic Framework-Based Adaptable Hydrogen Sulfide Delivery System for Regulating Neuroregeneration Microenvironment in Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Dynamic microglia/macrophage infiltration during spinal cord regeneration in larval sea lamprey. — PubMed · 2025 · Journal Article
- Hyaluronan-bisphosphonate conjugate: A macromolecular anti-inflammatory agent and gas delivery system for neuroimmunomodulation in spinal cord injury. — PubMed · 2025 · Journal Article
- Hyaluronic acid methacryloyl hydrogel with sustained IL-10 release promotes macrophage M2 polarization and motor function after spinal cord injury. — PubMed · 2025 · Journal Article
- Spatiotemporal Targeted Delivery of Biomimetic Bacterial Outer Membrane Nanoparticles for Enhanced Spinal Cord Injury Repair. — PubMed · 2025 · Journal Article
- Identifying Microglia and Peripheral Infiltrating Macrophages in the Injured Spinal Cords Using Flow Cytometry. — PubMed · 2025 · Journal Article
- Engineered small extracellular vesicles for targeted delivery of perlecan to stabilise the blood-spinal cord barrier after spinal cord injury. — PubMed · 2025 · Journal Article
- Photobiomodulation regulates inflammation and autophagy in spinal cord injury through NLRP3/Caspase-1/IL-1β pathway by targeting TLR2. — PubMed · 2025 · Journal Article
- Systemic stem cell treatment rescues injured motoneurons by reducing L-selectin expression on leukocytes. — PubMed · 2025 · Journal Article
- Reduced White Matter Damage and Lower Neuroinflammatory Potential of Microglia and Macrophages in Hri/Eif2ak1 (-/-) Mice After Contusive Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Regulation of Neuroimmune Microenvironment by PLA/GO/Anti-TNF-α Composite to Enhance Neurological Repair After Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Combined treatment targeting Ca2+ store mediated Ca2+ release and store-operated calcium entry reduces secondary axonal degeneration and improves functional outcome after SCI. — PubMed · 2025 · Journal Article
- Depletion of Cell Adhesion Molecule L1 from Microglia and Macrophages Reduces Recovery After Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Mineral coated microparticles delivering Interleukin-4, Interleukin-10, and Interleukin-13 reduce inflammation and improve function after spinal cord injury in a rat. — PubMed · 2025 · Journal Article
- Macrophage-targeted Mms6 mRNA-lipid nanoparticles promote locomotor functional recovery after traumatic spinal cord injury in mice. — PubMed · 2025 · Journal Article
- Centripetal migration and prolonged retention of microglia promotes spinal cord injury repair. — PubMed · 2025 · Journal Article
- NLRP3 inflammasome promotes functional repair after spinal cord injury in mice by regulating autophagy and its mechanism. — PubMed · 2025 · Journal Article
- Conditional deletion of IκBζ in hematopoietic cells promotes functional recovery after spinal cord injury in mice. — PubMed · 2025 · Journal Article
- Nerve-Derived Extracellular Matrix Promotes Neural Differentiation of Bone Marrow Stromal Cells and Enhances Interleukin-4 Efficacy for Advanced Nerve Regeneration. — PubMed · 2025 · Journal Article
- Neutrophil membrane-coated multifunctional biomimetic nanoparticles for spinal cord injuries. — PubMed · 2025 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 2 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1037078 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 4 · this programme has 1301 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("macrophage" OR "macrophage polarization" OR "autologous incubated macrophage") - Crossref
spinal cord injury macrophage macrophage polarization - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Macrophages"[MeSH Terms] OR "macrophage"[Title/Abstract] OR "macrophage polarization"[Title/Abstract] OR "autologous incubated macrophage"[Title/Abstract])