A subject this map covers
Macrophage therapy and polarisation
Part of: Inflammation and immune response
What belongs here
Delivering or reprogramming macrophages to change the character of inflammation at the injury.
What does not belong here, however close it looks
Describing what macrophages do without intervening is mechanism, not therapy; such a record stays in the parent concept.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 265 records · 1967–2026
- Indexed as work in animals: 781 records · 1966–2026
- Indexed as laboratory work: 41 records · 1988–2026
- The source has not said who or what was studied: 211 records · 1999–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1298 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Decellularized tissue matrices hydrogels functionalized with extracellular vesicles promote macrophage reprogramming and neural stem cell differentiation for spinal cord injury repair. — PubMed · 2025 · Journal Article
- NIR-Responsive Functionalized Nanoflower for Acute Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Formoterol alters chemokine expression and ameliorates pain behaviors after moderate spinal cord injury in female mice. — PubMed · 2025 · Journal Article
- Macropinocytosis enhances foamy macrophage formation and cholesterol crystallization to activate NLRP3 inflammasome after spinal cord injury. — PubMed · 2025 · Journal Article
- Kif15 regulates Coro1a(+) cell migration and phagocytosis in zebrafish after spinal cord injury. — PubMed · 2025 · Journal Article
- Cross-species comparisons between pigs and mice reveal conserved sex-specific intraspinal inflammatory responses after spinal cord injury. — PubMed · 2025 · Journal Article
- Hydrogel loaded with cerium-manganese nanoparticles and nerve growth factor enhances spinal cord injury repair by modulating immune microenvironment and promoting neuronal regeneration. — PubMed · 2025 · Journal Article
- Spinal cord injury enhances lung inflammation and exacerbates immune response following exposure to LPS. — PubMed · 2025 · Journal Article
- Biomimetic "Trojan Horse" Fibers Modulate Innate Immunity Cascades for Nerve Regeneration. — PubMed · 2025 · Journal Article
- Amantadine modulates novel macrophage phenotypes to enhance neural repair following spinal cord injury. — PubMed · 2025 · Journal Article
- A reactive oxygen species-responsive hydrogel loaded with Apelin-13 promotes the repair of spinal cord injury by regulating macrophage M1/M2 polarization and neuroinflammation. — PubMed · 2025 · Journal Article
- A cryo-shocked M2 macrophages based treatment strategy promoting repair of spinal cord injury via immunomodulation and axonal regeneration effects. — PubMed · 2025 · Journal Article
- Cytosolic phospholipase A2 in infiltrating monocyte derived macrophages does not impair recovery after spinal cord injury in female mice. — PubMed · 2025 · Journal Article
- Application of Adipose Extracellular Matrix and Reduced Graphene Oxide Nanocomposites for Spinal Cord Injury Repair. — PubMed · 2025 · Journal Article
- BHLHE40 regulates microglia polarization after spinal cord injury via the NF-κB pathway. — PubMed · 2025 · Journal Article
- Cold atmospheric plasma-activated saline alleviates secondary injury post-SCI by inhibiting extracellular matrix remodeling and infiltration of proinflammatory macrophages. — PubMed · 2025 · Journal Article
- Nonresolving Neuroinflammation Regulates Axon Regeneration in Chronic Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Plasmalogens Activate AKT/mTOR Signaling to Attenuate Reactive Oxygen Species Production in Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Single-cell analysis combined with transcriptome sequencing identifies autophagy hub genes in macrophages after spinal cord injury. — PubMed · 2025 · Journal Article
- IL-18 Blockage Reduces Neuroinflammation and Promotes Functional Recovery in a Mouse Model of Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Amplification of Metalloregulatory Proteins in Macrophages by Bioactive ZnMn@SF Hydrogels for Spinal Cord Injury Repair. — PubMed · 2024 · Journal Article
- Genetic deletion of the apoptosis associated speck like protein containing a card in LysM(+) macrophages attenuates spinal cord injury by regulating M1/M2 polarization through ASC-dependent inflammasome signaling axis. — PubMed · 2024 · Journal Article
- Interleukin-3 Modulates Macrophage Phagocytic Activity and Promotes Spinal Cord Injury Repair. — PubMed · 2024 · Journal Article
- Borneol-Functionalized Macrophage Membrane-Encapsulated Mesoporous Selenium Nanoparticles Loaded with Resveratrol for the Treatment of Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Constructing Electron-Rich Ru Clusters on Non-Stoichiometric Copper Hydroxide for Superior Biocatalytic ROS Scavenging to Treat Inflammatory Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Building-Block Size Mediates Microporous Annealed Particle Hydrogel Tube Microenvironment Following Spinal Cord Injury. — PubMed · 2024 · Journal Article
- High mobility group box-1 protein promotes astrocytic CCL5 production through the MAPK/NF-κB pathway following spinal cord injury. — PubMed · 2024 · Journal Article
- Contribution of ApoB-100/SORT1-Mediated Immune Microenvironment in Regulating Oxidative Stress, Inflammation, and Ferroptosis After Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Low-Dose LPS Modulates Microglia/Macrophages Phenotypic Transformation to Amplify Rehabilitation Effects in Chronic Spinal Cord Injured (CSCI) Mice. — PubMed · 2024 · Journal Article
- Macrophage GIT1 promotes oligodendrocyte precursor cell differentiation and remyelination after spinal cord injury. — PubMed · 2024 · Journal Article
- Photobiomodulation Increases M2-Type Polarization of Macrophages by Inhibiting Versican Production After Spinal Cord Injury. — PubMed · 2024 · Journal Article
- UAMC-3203 inhibits ferroptosis and promotes functional recovery in rats with spinal cord injury. — PubMed · 2024 · Journal Article
- Delayed administration of interleukin-4 coacervate alleviates the neurotoxic phenotype of astrocytes and promotes functional recovery after a contusion spinal cord injury. — PubMed · 2024 · Journal Article
- Transplantation of miR-145a-5p modified M2 type microglia promotes the tissue repair of spinal cord injury in mice. — PubMed · 2024 · Journal Article
- Carboxymethyl cellulose/quaternized chitosan hydrogel loaded with polydopamine nanoparticles promotes spinal cord injury recovery by anti-ferroptosis and M1/M2 polarization modulation. — PubMed · 2024 · Journal Article
- Neutrophil immune profile guides spinal cord regeneration in zebrafish. — PubMed · 2024 · Journal Article
- IPSC-NSCs-derived exosomal let-7b-5p improves motor function after spinal cord Injury by modulating microglial/macrophage pyroptosis. — PubMed · 2024 · Journal Article
- Neuroimmune modulating and energy supporting nanozyme-mimic scaffold synergistically promotes axon regeneration after spinal cord injury. — PubMed · 2024 · Journal Article
- Enhancing motor functional recovery in spinal cord injury through pharmacological inhibition of Dickkopf-1 with BHQ880 antibody. — PubMed · 2024 · Journal Article
- Exosomes derived from vMIP-II-Lamp2b gene-modified M2 cells provide neuroprotection by targeting the injured spinal cord, inhibiting chemokine signals and modulating microglia/macrophage polarization in mice. — PubMed · 2024 · Journal Article
- Targeting foamy macrophages by manipulating ABCA1 expression to facilitate lesion healing in the injured spinal cord. — PubMed · 2024 · Journal Article
- Il34 rescues metronidazole-induced impairment of spinal cord regeneration in zebrafish central nervous system. — PubMed · 2024 · Journal Article
- Repair spinal cord injury with a versatile anti-oxidant and neural regenerative nanoplatform. — PubMed · 2024 · Journal Article
- Myeloid Cell Association with Spinal Cord Injury-Induced Neuropathic Pain and Depressive-like Behaviors in LysM-eGFP Mice. — PubMed · 2024 · Journal Article
- Prussian blue analogues improves the microenvironment after spinal cord injury by regulating Zn. — PubMed · 2024 · Journal Article
- SP1 transcriptionally activates HTR2B to aggravate traumatic spinal cord injury by shifting microglial M1/M2 polarization. — PubMed · 2024 · Journal Article
- Interleukin-4 from curcumin-activated OECs emerges as a central modulator for increasing M2 polarization of microglia/macrophage in OEC anti-inflammatory activity for functional repair of spinal cord injury. — PubMed · 2024 · Journal Article
- Acetyl-11-keto-beta-boswellic acid modulates macrophage polarization and Schwann cell migration to accelerate spinal cord injury repair in rats. — PubMed · 2024 · Journal Article
- Engineered Macrophage Membrane-Coated Nanoparticles with Enhanced CCR2 Expression Promote Spinal Cord Injury Repair by Suppressing Neuroinflammation and Neuronal death. — PubMed · 2024 · Journal Article
- Rab3a attenuates spinal cord injury by mediating vesicle release. — PubMed · 2024 · Journal Article
- Injectable and Photocurable Gene Scaffold Facilitates Efficient Repair of Spinal Cord Injury. — PubMed · 2024 · Journal Article
- PI3K signaling promotes formation of lipid-laden foamy macrophages at the spinal cord injury site. — PubMed · 2024 · Journal Article
- HIF-1α promotes astrocytic production of macrophage migration inhibitory factor following spinal cord injury. — PubMed · 2023 · Journal Article
- Schwann Cell-Derived Exosomes and Methylprednisolone Composite Patch for Spinal Cord Injury Repair. — PubMed · 2023 · Journal Article
- Inhibition of UTX/KDM6A improves recovery of spinal cord injury by attenuating BSCB permeability and macrophage infiltration through the MLCK/p-MLC pathway. — PubMed · 2023 · Journal Article
- Zinc deficiency impairs axonal regeneration and functional recovery after spinal cord injury by modulating macrophage polarization via NF-κB pathway. — PubMed · 2023 · Journal Article
- Deletion of CD47 from Schwann cells and macrophages hastens myelin disruption/dismantling and scavenging in Schwann cells and augments myelin debris phagocytosis in macrophages. — PubMed · 2023 · Journal Article
- Encapsulation of Selenium Nanoparticles and Metformin in Macrophage-Derived Cell Membranes for the Treatment of Spinal Cord Injury. — PubMed · 2023 · Journal Article
- An In Vitro and Ex Vivo Analysis of the Potential of GelMA Hydrogels as a Therapeutic Platform for Preclinical Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Rapid and Efficient Enrichment of Mouse Spinal Cord Microglia. — PubMed · 2023 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 2 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1037078 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 4 · this programme has 1301 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("macrophage" OR "macrophage polarization" OR "autologous incubated macrophage") - Crossref
spinal cord injury macrophage macrophage polarization - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Macrophages"[MeSH Terms] OR "macrophage"[Title/Abstract] OR "macrophage polarization"[Title/Abstract] OR "autologous incubated macrophage"[Title/Abstract])