A subject this map covers
Myelin inhibitor blockade
Part of: Axon growth and regeneration
This map follows this subject as an approach
What belongs here
Lifting the inhibitory myelin signals that stop a fibre growing.
What does not belong here, however close it looks
Remyelination to restore conduction is a different aim — the oligodendrocyte-progenitor concept.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 124 records · 1983–2026
- Indexed as work in animals: 268 records · 1977–2025
- Indexed as laboratory work: 19 records · 1986–2018
- The source has not said who or what was studied: 58 records · 2002–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
469 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- A combination immunomodulatory treatment promotes neuroprotection and locomotor recovery after contusion SCI. — PubMed · 2011 · Journal Article
- Combination of NEP 1-40 infusion and bone marrow-derived neurospheres transplantation inhibit glial scar formation and promote functional recovery after rat spinal cord injury. — PubMed · 2011 · Journal Article
- Developmental changes of gene expression after spinal cord injury in neonatal opossums. — PubMed · 2010 · Journal Article
- Nano PGE1 promoted the recovery from spinal cord injury-induced motor dysfunction through its accumulation and sustained release. — PubMed · 2010 · Journal Article
- Characterization of a graded cervical hemicontusion spinal cord injury model in adult male rats. — PubMed · 2010 · Journal Article
- Nogo receptor deletion and multimodal exercise improve distinct aspects of recovery in cervical spinal cord injury. — PubMed · 2010 · Journal Article
- [Lentiviral vector-mediated RNA interfere gene Nogo receptor to repair spinal cord injury]. — PubMed · 2010 · Journal Article
- Hyaluronic acid hydrogel modified with nogo-66 receptor antibody and poly-L-lysine to promote axon regrowth after spinal cord injury. — PubMed · 2010 · Journal Article
- Predifferentiated embryonic stem cells promote functional recovery after spinal cord compressive injury. — PubMed · 2010 · Journal Article
- Combined genetic attenuation of myelin and semaphorin-mediated growth inhibition is insufficient to promote serotonergic axon regeneration. — PubMed · 2010 · Journal Article
- Genetic deletion and pharmacological inhibition of Nogo-66 receptor impairs cognitive outcome after traumatic brain injury in mice. — PubMed · 2010 · Journal Article
- NgR expression in macrophages promotes nerve regeneration after spinal cord injury in rats. — PubMed · 2010 · Journal Article
- Nogo-A antibodies and training reduce muscle spasms in spinal cord-injured rats. — PubMed · 2010 · Journal Article
- Assessing spinal axon regeneration and sprouting in Nogo-, MAG-, and OMgp-deficient mice. — PubMed · 2010 · Comparative Study
- Immunization with neural-derived antigens inhibits lipid peroxidation after spinal cord injury. — PubMed · 2010 · Journal Article
- MAG and OMgp synergize with Nogo-A to restrict axonal growth and neurological recovery after spinal cord trauma. — PubMed · 2010 · Journal Article
- Schwann cells differentiated from spheroid-forming cells of rat subcutaneous fat tissue myelinate axons in the spinal cord injury. — PubMed · 2010 · Journal Article
- Nogo-A expresses on neural stem cell surface. — PubMed · 2010 · Journal Article
- Therapeutic DNA vaccination as a repair strategy following spinal cord injury. — PubMed · 2010 · Journal Article The source marks this record as retracted.
- Bone morphogenetic proteins mediate cellular response and, together with Noggin, regulate astrocyte differentiation after spinal cord injury. — PubMed · 2010 · Journal Article
- [Construction and screening of neurite outgrowth inhibitory 66 eukaryotic expression vectors]. — PubMed · 2010 · Journal Article
- A large-scale chemical screen for regulators of the arginase 1 promoter identifies the soy isoflavone daidzeinas a clinically approved small molecule that can promote neuronal protection or regeneration via a cAMP-independent pathway. — PubMed · 2010 · Journal Article
- A retinoic acid receptor beta agonist (CD2019) overcomes inhibition of axonal outgrowth via phosphoinositide 3-kinase signalling in the injured adult spinal cord. — PubMed · 2010 · Journal Article
- [Treatment of spinal cord injury by transplanting neural stem cells with NgR gene silencing]. — PubMed · 2010 · Journal Article
- Rho-associated kinase II (ROCKII) limits axonal growth after trauma within the adult mouse spinal cord. — PubMed · 2009 · Journal Article
- Temporospatial expression and cellular localization of oligodendrocyte myelin glycoprotein (OMgp) after traumatic spinal cord injury in adult rats. — PubMed · 2009 · Journal Article
- Generation of an OMgp allelic series in mice. — PubMed · 2009 · Journal Article
- Enrichment of rat oligodendrocyte progenitor cells by magnetic cell sorting. — PubMed · 2009 · Journal Article
- Convergence of cells from the progenitor fraction of adult olfactory bulb tissue to remyelinating glia in demyelinating spinal cord lesions. — PubMed · 2009 · Journal Article
- HSV-mediated transfer of artemin overcomes myelin inhibition to improve outcome after spinal cord injury. — PubMed · 2009 · Journal Article
- Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice. — PubMed · 2009 · Journal Article
- Effects of progesterone on oligodendrocyte progenitors, oligodendrocyte transcription factors, and myelin proteins following spinal cord injury. — PubMed · 2009 · Journal Article
- Tamoxifen attenuates inflammatory-mediated damage and improves functional outcome after spinal cord injury in rats. — PubMed · 2009 · Journal Article
- Postinjury niches induce temporal shifts in progenitor fates to direct lesion repair after spinal cord injury. — PubMed · 2009 · Journal Article
- Vaccination with dendritic cells pulsed with homogenate protein of spinal cord promotes functional recovery from spinal cord injury in mice. — PubMed · 2009 · Journal Article
- Acute rolipram/thalidomide treatment improves tissue sparing and locomotion after experimental spinal cord injury. — PubMed · 2009 · Journal Article
- Intraspinal sprouting of unmyelinated pelvic afferents after complete spinal cord injury is correlated with autonomic dysreflexia induced by visceral pain. — PubMed · 2009 · Journal Article
- Anti-Nogo-A antibody treatment promotes recovery of manual dexterity after unilateral cervical lesion in adult primates--re-examination and extension of behavioral data. — PubMed · 2009 · Journal Article
- Behavioral characterization of mice lacking the neurite outgrowth inhibitor Nogo-A. — PubMed · 2009 · Journal Article
- Functional recovery after the transplantation of neurally differentiated mesenchymal stem cells derived from bone marrow in a rat model of spinal cord injury. — PubMed · 2009 · Journal Article
- Neuropathic pain behaviours in a chronic-relapsing model of experimental autoimmune encephalomyelitis (EAE). — PubMed · 2009 · Journal Article
- [The primary evaluation of its safety and immune effect of NogoA vaccination for spinal cord injury]. — PubMed · 2008 · Journal Article
- Effects of autoimmunity on recovery of function in adult rats following spinal cord injury. — PubMed · 2008 · Journal Article
- Assessment of functional recovery and axonal sprouting in oligodendrocyte-myelin glycoprotein (OMgp) null mice after spinal cord injury. — PubMed · 2008 · Journal Article
- DNA vaccination efficiently induces antibodies to Nogo-A and does not exacerbate experimental autoimmune encephalomyelitis. — PubMed · 2008 · Journal Article
- Characterizing white matter damage in rat spinal cord with quantitative MRI and histology. — PubMed · 2008 · Journal Article
- Nogo-66 receptor antagonist peptide (NEP1-40) administration promotes functional recovery and axonal growth after lateral funiculus injury in the adult rat. — PubMed · 2008 · Journal Article
- Nogo-66 promotes the differentiation of neural progenitors into astroglial lineage cells through mTOR-STAT3 pathway. — PubMed · 2008 · Journal Article
- Methylprednisolone protects oligodendrocytes but not neurons after spinal cord injury. — PubMed · 2008 · Journal Article
- Reimplantation of avulsed lumbosacral ventral roots in the rat ameliorates injury-induced degeneration of primary afferent axon collaterals in the spinal dorsal columns. — PubMed · 2008 · Journal Article
- A re-assessment of the effects of a Nogo-66 receptor antagonist on regenerative growth of axons and locomotor recovery after spinal cord injury in mice. — PubMed · 2008 · Journal Article
- Anti-Nogo-A antibody treatment does not prevent cell body shrinkage in the motor cortex in adult monkeys subjected to unilateral cervical cord lesion. — PubMed · 2008 · Comparative Study
- [Molecular mechanism and regulation of axon growth inhibition]. — PubMed · 2007 · Journal Article
- LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis. — PubMed · 2007 · Journal Article
- Distinct types of microglial activation in white and grey matter of rat lumbosacral cord after mid-thoracic spinal transection. — PubMed · 2007 · Journal Article
- Expression of oligodendrocyte myelin glycoprotein and its receptor NgR after the injury of rat central nervous system. — PubMed · 2007 · Journal Article
- Contactin1a expression is associated with oligodendrocyte differentiation and axonal regeneration in the central nervous system of zebrafish. — PubMed · 2007 · Journal Article
- Withanoside IV improves hindlimb function by facilitating axonal growth and increase in peripheral nervous system myelin level after spinal cord injury. — PubMed · 2007 · Journal Article
- DNA vaccine against NgR promotes functional recovery after spinal cord injury in adult rats. — PubMed · 2007 · Journal Article
- Heme oxygenase-1 stabilizes the blood-spinal cord barrier and limits oxidative stress and white matter damage in the acutely injured murine spinal cord. — PubMed · 2007 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 1 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1641516 · this programme has 49 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it has nothing | asked on 2026-10-12 | the source found 0 · this programme has 452 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("anti-Nogo" OR "Nogo-A antibody" OR "myelin associated inhibitor") - Crossref
spinal cord injury anti-Nogo Nogo-A antibody - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Myelin Proteins"[MeSH Terms] OR "Nogo Proteins"[MeSH Terms] OR "anti-Nogo"[Title/Abstract] OR "Nogo-A antibody"[Title/Abstract] OR "myelin associated inhibitor"[Title/Abstract])