A subject this map covers
Myelin inhibitor blockade
Part of: Axon growth and regeneration
This map follows this subject as an approach
What belongs here
Lifting the inhibitory myelin signals that stop a fibre growing.
What does not belong here, however close it looks
Remyelination to restore conduction is a different aim — the oligodendrocyte-progenitor concept.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 124 records · 1983–2026
- Indexed as work in animals: 268 records · 1977–2025
- Indexed as laboratory work: 19 records · 1986–2018
- The source has not said who or what was studied: 58 records · 2002–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
469 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Influence of the intensity, level and phase of spinal cord injury on the proliferation of T cells and T-cell-dependent antibody reactions in rats. — PubMed · 2007 · Journal Article
- Behavioral, histological, and ex vivo magnetic resonance imaging assessment of graded contusion spinal cord injury in mice. — PubMed · 2007 · Journal Article
- Central nervous system and non-central nervous system antigen vaccines exacerbate neuropathology caused by nerve injury. — PubMed · 2007 · Journal Article
- Expression profile of receptors for myelin-associated inhibitors of axonal regeneration in the intact and injured mouse central nervous system. — PubMed · 2007 · Journal Article
- Oligodendrocytes and radial glia derived from adult rat spinal cord progenitors: morphological and immunocytochemical characterization. — PubMed · 2007 · Journal Article
- Erythropoietin-mediated preservation of the white matter in rat spinal cord injury. — PubMed · 2007 · Journal Article
- Positioned to inhibit: netrin-1 and netrin receptor expression after spinal cord injury. — PubMed · 2006 · Journal Article
- Leukemia inhibitory factor arrests oligodendrocyte death and demyelination in spinal cord injury. — PubMed · 2006 · Comparative Study
- Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury. — PubMed · 2006 · Journal Article
- Myelin-associated glycoprotein inhibits microtubule assembly by a Rho-kinase-dependent mechanism. — PubMed · 2006 · Journal Article
- Introduction of the MASH1 gene into mouse embryonic stem cells leads to differentiation of motoneuron precursors lacking Nogo receptor expression that can be applicable for transplantation to spinal cord injury. — PubMed · 2006 · Journal Article
- Antibodies against the NG2 proteoglycan promote the regeneration of sensory axons within the dorsal columns of the spinal cord. — PubMed · 2006 · Comparative Study
- Intrathecally infused antibodies against Nogo-A penetrate the CNS and downregulate the endogenous neurite growth inhibitor Nogo-A. — PubMed · 2006 · Journal Article
- Progesterone increases the expression of myelin basic protein and the number of cells showing NG2 immunostaining in the lesioned spinal cord. — PubMed · 2006 · Journal Article
- Progesterone treatment of spinal cord injury: Effects on receptors, neurotrophins, and myelination. — PubMed · 2006 · Journal Article
- Incomplete Freund's adjuvant enhances locomotor performance following spinal cord injury. — PubMed · 2005 · Journal Article
- Nogo-A antibody improves regeneration and locomotion of spinal cord-injured rats. — PubMed · 2005 · Comparative Study
- Effect of combined treatment with methylprednisolone and soluble Nogo-66 receptor after rat spinal cord injury. — PubMed · 2005 · Comparative Study
- Why do Nogo/Nogo-66 receptor gene knockouts result in inferior regeneration compared to treatment with neutralizing agents? — PubMed · 2005 · Comparative Study
- Molecular control of physiological and pathological T-cell recruitment after mouse spinal cord injury. — PubMed · 2005 · Journal Article
- Prolonged lesional expression of RhoA and RhoB following spinal cord injury. — PubMed · 2005 · Comparative Study
- Immune regulatory mechanisms influence early pathology in spinal cord injury and in spontaneous autoimmune encephalomyelitis. — PubMed · 2005 · Comparative Study
- Wallerian degeneration involves Rho/Rho-kinase signaling. — PubMed · 2005 · Journal Article
- Real-time quantitative PCR analysis of temporal-spatial alterations in gene expression after spinal cord contusion. — PubMed · 2005 · Comparative Study
- Transgenic inhibition of Nogo-66 receptor function allows axonal sprouting and improved locomotion after spinal injury. — PubMed · 2005 · Journal Article
- Axon regeneration: it's getting crowded at the gates of TROY. — PubMed · 2005 · Journal Article
- Neuronal plasticity after spinal cord injury: identification of a gene cluster driving neurite outgrowth. — PubMed · 2005 · Journal Article
- Immunity to the extracellular domain of Nogo-A modulates experimental autoimmune encephalomyelitis. — PubMed · 2004 · Journal Article
- Blockade of Nogo-66, myelin-associated glycoprotein, and oligodendrocyte myelin glycoprotein by soluble Nogo-66 receptor promotes axonal sprouting and recovery after spinal injury. — PubMed · 2004 · Journal Article
- K+ channel blockade impairs remyelination in the cuprizone model. — PubMed · 2004 · Journal Article
- Calcium channel blockers ameliorate disease in a mouse model of multiple sclerosis. — PubMed · 2004 · Comparative Study
- Behavioral testing strategies in a localized animal model of multiple sclerosis. — PubMed · 2004 · Comparative Study
- The number of cells expressing the myelin-supporting oligodendrocyte marker PLP-exon 3b remains unchanged in Wallerian degeneration. — PubMed · 2004 · Journal Article
- The neurite outgrowth inhibitor Nogo A is involved in autoimmune-mediated demyelination. — PubMed · 2004 · Comparative Study
- The therapeutic window after spinal cord injury can accommodate T cell-based vaccination and methylprednisolone in rats. — PubMed · 2004 · Comparative Study
- Passive or active immunization with myelin basic protein impairs neurological function and exacerbates neuropathology after spinal cord injury in rats. — PubMed · 2004 · Journal Article
- Molecular evidence of repair and plasticity following spinal cord injury. — PubMed · 2004 · Comparative Study
- Activation of Rho in the injured axons following spinal cord injury. — PubMed · 2004 · Journal Article
- PKC mediates inhibitory effects of myelin and chondroitin sulfate proteoglycans on axonal regeneration. — PubMed · 2004 · Journal Article
- Prevention of gliotic scar formation by NeuroGel allows partial endogenous repair of transected cat spinal cord. — PubMed · 2004 · Journal Article
- Cytoplasmic p21(Cip1/WAF1) enhances axonal regeneration and functional recovery after spinal cord injury in rats. — PubMed · 2004 · Journal Article
- Guanosine promotes myelination and functional recovery in chronic spinal injury. — PubMed · 2003 · Comparative Study
- Nogo-A expression in the intact and injured nervous system. — PubMed · 2003 · Journal Article
- Rapid induction of autoantibodies against Nogo-A and MOG in the absence of an encephalitogenic T cell response: implication for immunotherapeutic approaches in neurological diseases. — PubMed · 2003 · Journal Article
- Calpain inhibitor prevented apoptosis and maintained transcription of proteolipid protein and myelin basic protein genes in rat spinal cord injury. — PubMed · 2003 · Journal Article
- Vaccination with dendritic cells pulsed with peptides of myelin basic protein promotes functional recovery from spinal cord injury. — PubMed · 2003 · Journal Article
- Immunization with myelin or recombinant Nogo-66/MAG in alum promotes axon regeneration and sprouting after corticospinal tract lesions in the spinal cord. — PubMed · 2003 · Comparative Study
- Axon regeneration in young adult mice lacking Nogo-A/B. — PubMed · 2003 · Journal Article
- Lack of enhanced spinal regeneration in Nogo-deficient mice. — PubMed · 2003 · Journal Article
- Systemic deletion of the myelin-associated outgrowth inhibitor Nogo-A improves regenerative and plastic responses after spinal cord injury. — PubMed · 2003 · Journal Article
- Activity-induced and developmental downregulation of the Nogo receptor. — PubMed · 2003 · Journal Article
- Combined therapy of methylprednisolone and brain-derived neurotrophic factor promotes axonal regeneration and functional recovery after spinal cord injury in rats. — PubMed · 2003 · Journal Article
- Rho kinase inhibition enhances axonal regeneration in the injured CNS. — PubMed · 2003 · Journal Article
- Neurotrophic factors attenuate microvascular permeability disturbances and axonal injury following trauma to the rat spinal cord. — PubMed · 2003 · Journal Article
- Neuroprotective autoimmunity: naturally occurring CD4+CD25+ regulatory T cells suppress the ability to withstand injury to the central nervous system. — PubMed · 2002 · Comparative Study
- Reorganization of descending motor tracts in the rat spinal cord. — PubMed · 2002 · Journal Article
- pSVPoMcat modifying Schwann cell to protect injured spinal neurons in rats. — PubMed · 2002 · Journal Article
- Neuroscience. It takes more than two to Nogo. — PubMed · 2002 · Journal Article
- Localization of Nogo-A and Nogo-66 receptor proteins at sites of axon-myelin and synaptic contact. — PubMed · 2002 · Comparative Study
- [New treatments for spinal cord injuries]. — PubMed · 2002 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 1 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1641516 · this programme has 49 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it has nothing | asked on 2026-10-12 | the source found 0 · this programme has 452 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("anti-Nogo" OR "Nogo-A antibody" OR "myelin associated inhibitor") - Crossref
spinal cord injury anti-Nogo Nogo-A antibody - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Myelin Proteins"[MeSH Terms] OR "Nogo Proteins"[MeSH Terms] OR "anti-Nogo"[Title/Abstract] OR "Nogo-A antibody"[Title/Abstract] OR "myelin associated inhibitor"[Title/Abstract])