A subject this map covers
Myelin inhibitor blockade
Part of: Axon growth and regeneration
This map follows this subject as an approach
What belongs here
Lifting the inhibitory myelin signals that stop a fibre growing.
What does not belong here, however close it looks
Remyelination to restore conduction is a different aim — the oligodendrocyte-progenitor concept.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 124 records · 1983–2026
- Indexed as work in animals: 268 records · 1977–2025
- Indexed as laboratory work: 19 records · 1986–2018
- The source has not said who or what was studied: 58 records · 2002–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
469 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Nogo-66 receptor antagonist peptide promotes axonal regeneration. — PubMed · 2002 · Journal Article
- Patterns of Nogo mRNA and protein expression in the developing and adult rat and after CNS lesions. — PubMed · 2002 · Journal Article
- Pathological CNS autoimmune disease triggered by traumatic spinal cord injury: implications for autoimmune vaccine therapy. — PubMed · 2002 · Journal Article
- Vaccination with a Nogo-A-derived peptide after incomplete spinal-cord injury promotes recovery via a T-cell-mediated neuroprotective response: comparison with other myelin antigens. — PubMed · 2001 · Comparative Study
- Differentiation of choroid plexus ependymal cells into astrocytes after grafting into the pre-lesioned spinal cord in mice. — PubMed · 2001 · Journal Article
- SCIP/Oct-6, Krox-20, and desert hedgehog mRNA expression during CNS remyelination by transplanted olfactory ensheathing cells. — PubMed · 2001 · Journal Article
- Increase of oligodendrocyte progenitor cells after spinal cord injury. — PubMed · 2001 · Journal Article
- Posttraumatic therapeutic vaccination with modified myelin self-antigen prevents complete paralysis while avoiding autoimmune disease. — PubMed · 2001 · Journal Article
- Protective autoimmunity is a physiological response to CNS trauma. — PubMed · 2001 · Journal Article
- Locomotor recovery in spinal cord-injured rats treated with an antibody neutralizing the myelin-associated neurite growth inhibitor Nogo-A. — PubMed · 2001 · Journal Article
- Diffusion anisotropy MRI for quantitative assessment of recovery in injured rat spinal cord. — PubMed · 2001 · Journal Article
- Passive or active immunization with myelin basic protein promotes recovery from spinal cord contusion. — PubMed · 2000 · Journal Article
- Reactions of oligodendrocytes to spinal cord injury: cell survival and myelin repair. — PubMed · 2000 · Journal Article
- Embryonic stem cells differentiate into oligodendrocytes and myelinate in culture and after spinal cord transplantation. — PubMed · 2000 · Journal Article
- Autoimmune T cells as potential neuroprotective therapy for spinal cord injury. — PubMed · 2000 · Letter
- Search for an IgG response against neural antigens in experimental spinal cord injury. — PubMed · 2000 · Journal Article
- Apoptotic cells associated with Wallerian degeneration after experimental spinal cord injury: a possible mechanism of oligodendroglial death. — PubMed · 1999 · Journal Article
- Death of oligodendrocytes and microglial phagocytosis of myelin precede immigration of Schwann cells into the spinal cord. — PubMed · 1999 · Journal Article
- Myelin gene expression after experimental contusive spinal cord injury. — PubMed · 1998 · Journal Article
- [Influence of intraspinal implantation of pSVP0MCAT genetically modified Schwann cell in regeneration of injured spinal cord]. — PubMed · 1998 · English Abstract
- Oligodendroglial reaction following spinal cord injury in rat: transient upregulation of MBP mRNA. — PubMed · 1998 · Journal Article
- Astrocytes and oligodendrocytes reactions after a total section of the rat spinal cord. — PubMed · 1998 · Journal Article
- Myelin-associated glycoprotein inhibits neurite/axon growth and causes growth cone collapse. — PubMed · 1996 · Journal Article
- Cryogenic spinal cord injury induces astrocytic gene expression of insulin-like growth factor I and insulin-like growth factor binding protein 2 during myelin regeneration. — PubMed · 1995 · Journal Article
- Suppression of the onset of myelination extends the permissive period for the functional repair of embryonic spinal cord. — PubMed · 1992 · Journal Article
- Release of endogenous neurochemicals may increase vascular permeability, induce edema and influence cell changes in trauma to the spinal cord. — PubMed · 1992 · Journal Article
- Chronic regenerative changes in the spinal cord after cord compression injury in rats. — PubMed · 1987 · Journal Article
- Molecular and anatomical correlates of spinal cord injury. — PubMed · 1985 · Journal Article
- Changes in myelin and axonal proteins in CaCl2-induced myelopathy in rat spinal cord. — PubMed · 1984 · Journal Article
- A biochemical investigation of spinal cord after contusive injury. — PubMed · 1982 · Journal Article
- The effects of spinal cord trauma on myelin. — PubMed · 1980 · Journal Article
- Studies on cell-mediated hypersensitivity to neural antigens after experimental spinal cord injury. — PubMed · 1977 · Journal Article
Indexed as laboratory work
- Cetuximab and Taxol co-modified collagen scaffolds show combination effects for the repair of acute spinal cord injury. — PubMed · 2018 · Journal Article
- Galectin-1 circumvents lysolecithin-induced demyelination through the modulation of microglial polarization/phagocytosis and oligodendroglial differentiation. — PubMed · 2016 · Journal Article
- Complement protein C1q modulates neurite outgrowth in vitro and spinal cord axon regeneration in vivo. — PubMed · 2015 · Journal Article
- Spinal motor neurite outgrowth over glial scar inhibitors is enhanced by coculture with bone marrow stromal cells. — PubMed · 2014 · Journal Article
- A novel growth-promoting pathway formed by GDNF-overexpressing Schwann cells promotes propriospinal axonal regeneration, synapse formation, and partial recovery of function after spinal cord injury. — PubMed · 2013 · Journal Article
- Spatio-temporal development of axonopathy in canine intervertebral disc disease as a translational large animal model for nonexperimental spinal cord injury. — PubMed · 2013 · Journal Article
- Microglial inhibitory factor (MIF/TKP) mitigates secondary damage following spinal cord injury. — PubMed · 2012 · Journal Article
- Acrolein induces myelin damage in mammalian spinal cord. — PubMed · 2011 · Journal Article
- Corticotrophin-releasing hormone (CRH) facilitates axon outgrowth. — PubMed · 2010 · Journal Article
- The effects of combining chondroitinase ABC and NEP1-40 on the corticospinal axon growth in organotypic co-cultures. — PubMed · 2010 · Journal Article
- Corticospinal neurons respond differentially to neurotrophins and myelin-associated glycoprotein in vitro. — PubMed · 2009 · Journal Article
- Axonal protective effects of the myelin-associated glycoprotein. — PubMed · 2009 · Journal Article
- Testing NMDA receptor block as a therapeutic strategy for reducing ischaemic damage to CNS white matter. — PubMed · 2008 · Journal Article
- The differentiation of rat adipose-derived stem cells into OEC-like cells on collagen scaffolds by co-culturing with OECs. — PubMed · 2007 · Journal Article
- Phenotypical analysis of adult rat olfactory ensheathing cells on 3-D collagen scaffolds. — PubMed · 2006 · Journal Article
- The Nogo-66 receptor: focusing myelin inhibition of axon regeneration. — PubMed · 2003 · Journal Article
- Molecular approaches to spinal cord repair. — PubMed · 2003 · Journal Article
- Influence of IN-1 antibody and acidic FGF-fibrin glue on the response of injured corticospinal tract axons to human Schwann cell grafts. — PubMed · 1997 · Journal Article
- Proteolytic enzymes in experimental spinal cord injury. — PubMed · 1986 · Comparative Study
The source has not said who or what was studied
- The Integrated Neurological Change Score Is a Sensitive Neurological Composite Measure to Evaluate Cervical Spinal Cord Injury Trials. — PubMed · 2026 · Journal Article
- Anti-Nogo-A NG101 treatment induces changes in spinal cord micro- and macrostructure following spinal cord injury — Crossref · 2026 · journal-article
- The Mechanism By Which MiR-Let-7b-Modified BMSCs Mediating Nogo/NgR Signaling Pathway In The Repair Of Spinal Cord Injury — Crossref · 2026 · journal-article
- Potential Pharmacologic Treatments in Spinal Cord Injury: A Narrative Review. — PubMed · 2025 · Journal Article
- Serum Nogo - A as a predictor of neurological recovery in spinal cord injury. — PubMed · 2025 · Journal Article
- Suppression of the Growth Inhibitor Nogo-A in Spinal Cord Injury: Preclinical Basis and First Clinical Studies — Crossref · 2025 · book-chapter
- Effects of exercise training on neurological recovery, TGF-β1, HIF-1α, and Nogo-NgR signaling pathways after spinal cord injury in rats — Crossref · 2023 · journal-article
- Myelin-associated glycoprotein alters the neuronal secretome and stimulates the release of TGFβ and proteins that affect neural plasticity. — PubMed · 2022 · Journal Article
- Retraction of: Effects of MicroRNA-494 on Astrocyte Proliferation and Synaptic Remodeling in the Spinal Cord of a Rat Model of Chronic Compressive Spinal Cord Injury by Regulating the Nogo/Ngr Signaling Pathway — Crossref · 2022 · journal-article The source marks this record as retracted.
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 1 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1641516 · this programme has 49 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it has nothing | asked on 2026-10-12 | the source found 0 · this programme has 452 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("anti-Nogo" OR "Nogo-A antibody" OR "myelin associated inhibitor") - Crossref
spinal cord injury anti-Nogo Nogo-A antibody - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Myelin Proteins"[MeSH Terms] OR "Nogo Proteins"[MeSH Terms] OR "anti-Nogo"[Title/Abstract] OR "Nogo-A antibody"[Title/Abstract] OR "myelin associated inhibitor"[Title/Abstract])