A subject this map covers
Inflammation and immune response
What belongs here
What immune cells do after injury — both as damage and as a necessary part of healing.
What does not belong here, however close it looks
Infection and sepsis are clinical management, a separate subject.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 769 records · 1981–2027
- Indexed as work in animals: 1704 records · 1975–2027
- Indexed as laboratory work: 73 records · 2001–2026
- The source has not said who or what was studied: 639 records · 1998–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3185 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Lycopene - A pleiotropic neuroprotective nutraceutical: Deciphering its therapeutic potentials in broad spectrum neurological disorders. — PubMed · 2020 · Journal Article
- Treatment with 5-methoxytryptophan attenuates microglia-induced neuroinflammation in spinal cord trauma. — PubMed · 2020 · Journal Article
- Age as a determinant of inflammatory response and survival of glia and axons after human traumatic spinal cord injury. — PubMed · 2020 · Journal Article
- Effective Modulation of CNS Inhibitory Microenvironment using Bioinspired Hybrid-Nanoscaffold-Based Therapeutic Interventions. — PubMed · 2020 · Journal Article
- Novel inhibitors of Rho-kinase mediated neuroinflammatory pathways and their potential application in recovery of injured spinal cord. — PubMed · 2020 · Journal Article
- Spatio-temporal and Cellular Expression Patterns of PTK7 in the Healthy and Traumatically Injured Rat and Human Spinal Cord. — PubMed · 2020 · Journal Article
- The Inhibition of Inflammatory Signaling Pathway by Secretory Leukocyte Protease Inhibitor can Improve Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Delayed microglial depletion after spinal cord injury reduces chronic inflammation and neurodegeneration in the brain and improves neurological recovery in male mice. — PubMed · 2020 · Journal Article
- The Beneficial Roles of SIRT1 in Neuroinflammation-Related Diseases. — PubMed · 2020 · Journal Article
- Transplantation of human urine-derived neural progenitor cells after spinal cord injury in rats. — PubMed · 2020 · Journal Article
- Microenvironment-responsive immunoregulatory electrospun fibers for promoting nerve function recovery. — PubMed · 2020 · Journal Article
- Inhibition of phosphodiesterase IV enzyme improves locomotor and sensory complications of spinal cord injury via altering microglial activity: Introduction of Roflumilast as an alternative therapy. — PubMed · 2020 · Journal Article
- Metabolites of neuroinflammation relate to neuropathic pain after spinal cord injury. — PubMed · 2020 · Journal Article
- TLR4 promotes microglial pyroptosis via lncRNA-F630028O10Rik by activating PI3K/AKT pathway after spinal cord injury. — PubMed · 2020 · Journal Article
- Cognitive Dysfunction in Persons with Chronic Spinal Cord Injuries. — PubMed · 2020 · Journal Article
- Intravenous administration of human amniotic mesenchymal stem cells improves outcomes in rats with acute traumatic spinal cord injury. — PubMed · 2020 · Journal Article
- Microglia and macrophage metabolism in CNS injury and disease: The role of immunometabolism in neurodegeneration and neurotrauma. — PubMed · 2020 · Journal Article
- Mitochondrial biogenesis as a therapeutic target for traumatic and neurodegenerative CNS diseases. — PubMed · 2020 · Journal Article
- Dementia, Depression, and Associated Brain Inflammatory Mechanisms after Spinal Cord Injury. — PubMed · 2020 · Journal Article
- MicroRNA-21-5p promotes the inflammatory response after spinal cord injury by targeting PLAG1. — PubMed · 2020 · Journal Article
- Cervical Spinal Cord Injury Shows Markedly Lower than Predicted Mortality (>72 Hours After Multiple Trauma) From Sepsis and Multiple Organ Failure. — PubMed · 2020 · Evaluation Study
- CRISPR, Prime Editing, Optogenetics, and DREADDs: New Therapeutic Approaches Provided by Emerging Technologies in the Treatment of Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Protective effect of sodium propionate in Aβ(1-42) -induced neurotoxicity and spinal cord trauma. — PubMed · 2020 · Journal Article
- Circulating PAMM, a novel antioxidant and anti-inflammatory protein, is elevated in acute SCI. — PubMed · 2020 · Journal Article
- The enhancement of CCL2 and CCL5 by human bone marrow-derived mesenchymal stem/stromal cells might contribute to inflammatory suppression and axonal extension after spinal cord injury. — PubMed · 2020 · Journal Article
- Exercise in multiple sclerosis and its models: Focus on the central nervous system outcomes. — PubMed · 2020 · Journal Article
- Inhibitors of Myelination and Remyelination, Bone Morphogenetic Proteins, are Upregulated in Human Neurological Disease. — PubMed · 2020 · Journal Article
- Treatment of rats with spinal cord injury using human bone marrow-derived stromal cells prepared by negative selection. — PubMed · 2020 · Comparative Study
- Efficacy of human HC016 cell transplants on neuroprotection and functional recovery in a rat model of acute spinal cord injury. — PubMed · 2020 · Journal Article
- Intracerebroventricular Delivery of Human Umbilical Cord Mesenchymal Stem Cells as a Promising Therapy for Repairing the Spinal Cord Injury Induced by Kainic Acid. — PubMed · 2020 · Journal Article
- Targeting the NLRP3 Inflammasome in Neuroinflammation: Health Promoting Effects of Dietary Phytochemicals in Neurological Disorders. — PubMed · 2020 · Journal Article
- The fate and function of oligodendrocyte progenitor cells after traumatic spinal cord injury. — PubMed · 2020 · Journal Article
- A Selective P2Y Purinergic Receptor Agonist 2-MesADP Enhances Locomotor Recovery after Acute Spinal Cord Injury. — PubMed · 2020 · Journal Article
- DUSP19 mediates spinal cord injury-induced apoptosis and inflammation in mouse primary microglia cells via the NF-kB signaling pathway. — PubMed · 2020 · Journal Article
- LPA receptor signaling as a therapeutic target for radical treatment of neuropathic pain and fibromyalgia. — PubMed · 2020 · Journal Article
- Role of NLRP3 Inflammasomes in Neuroinflammation Diseases. — PubMed · 2020 · Journal Article
- Gal-3 is a potential biomarker for spinal cord injury and Gal-3 deficiency attenuates neuroinflammation through ROS/TXNIP/NLRP3 signaling pathway. — PubMed · 2019 · Journal Article
- B Cell-Activating Factor Is Associated with Testosterone and Smoking Status in Non-Ambulatory Men with Chronic Spinal Cord Injury. — PubMed · 2019 · Journal Article
- How T'reg-ulate healing of the injured spinal cord? — PubMed · 2019 · Editorial
- Sirtuin4 suppresses the anti-neuroinflammatory activity of infiltrating regulatory T cells in the traumatically injured spinal cord. — PubMed · 2019 · Journal Article
- Systemic Immune Response to Traumatic CNS Injuries-Are Extracellular Vesicles the Missing Link? — PubMed · 2019 · Journal Article
- The changes in systemic monocytes in humans undergoing surgical decompression for degenerative cervical myelopathy may influence clinical neurological recovery. — PubMed · 2019 · Journal Article
- Myelin status and oligodendrocyte lineage cells over time after spinal cord injury: What do we know and what still needs to be unwrapped? — PubMed · 2019 · Journal Article
- Resolution of neuroinflammation: mechanisms and potential therapeutic option. — PubMed · 2019 · Journal Article
- Combinational protective therapy for spinal cord injury medicated by sialic acid-driven and polyethylene glycol based micelles. — PubMed · 2019 · Journal Article
- Physical impacts of PLGA scaffolding on hMSCs: Recovery neurobiology insight for implant design to treat spinal cord injury. — PubMed · 2019 · Journal Article
- Stem cells from the dental apical papilla in extracellular matrix hydrogels mitigate inflammation of microglial cells. — PubMed · 2019 · Journal Article
- Role of microglia in spinal cord injury. — PubMed · 2019 · Journal Article
- Lysozyme elicits pain during nerve injury by neuronal Toll-like receptor 4 activation and has therapeutic potential in neuropathic pain. — PubMed · 2019 · Journal Article
- Matrix metalloproteinase signals following neurotrauma are right on cue. — PubMed · 2019 · Journal Article
- The Neuroprotective Effects of Astaxanthin: Therapeutic Targets and Clinical Perspective. — PubMed · 2019 · Journal Article
- The effects of human immunoglobulin G on enhancing tissue protection and neurobehavioral recovery after traumatic cervical spinal cord injury are mediated through the neurovascular unit. — PubMed · 2019 · Journal Article
- Tracking the evolution of CNS remyelinating lesion in mice with neutral red dye. — PubMed · 2019 · Journal Article
- Innovative mouse model mimicking human-like features of spinal cord injury: efficacy of Docosahexaenoic acid on acute and chronic phases. — PubMed · 2019 · Journal Article
- Regenerative neuroimmunology: The impact of immune and neural stem cell interactions for translation in neurodegeneration and repair. — PubMed · 2019 · Editorial
- The benefits of neuroinflammation for the repair of the injured central nervous system. — PubMed · 2019 · Journal Article
- Alpha-synuclein induces microglial migration via PKM2-dependent glycolysis. — PubMed · 2019 · Journal Article
- BRD4 inhibition attenuates inflammatory response in microglia and facilitates recovery after spinal cord injury in rats. — PubMed · 2019 · Journal Article
- Multipotent Adult Progenitor Cells, but Not Tissue Inhibitor of Matrix Metalloproteinase-3, Increase Tissue Sparing and Reduce Urological Complications following Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Polydatin alleviates traumatic spinal cord injury by reducing microglial inflammation via regulation of iNOS and NLRP3 inflammasome pathway. — PubMed · 2019 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 3 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851312 · this programme has 48 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 29 · this programme has 3219 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroinflammation" OR "microglia" OR "immune response") - Crossref
spinal cord injury neuroinflammation microglia - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neurogenic Inflammation"[MeSH Terms] OR "Microglia"[MeSH Terms] OR "Neuroimmunomodulation"[MeSH Terms] OR "neuroinflammation"[Title/Abstract] OR "microglia"[Title/Abstract] OR "immune response"[Title/Abstract])