A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Facilitators and Barriers to Spinal Cord Injury Clinical Trial Participation: Multi-National Perspective of People Living with Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Mediating the Secondary Effects of Spinal Cord Injury Through Optimization of Key Physiologic Parameters. — PubMed · 2016 · Journal Article
- Cannabinoids to treat spinal cord injury. — PubMed · 2016 · Journal Article
- Administration of Uric Acid in the Emergency Treatment of Acute Ischemic Stroke. — PubMed · 2016 · Journal Article
- Cytokine and Growth Factor Activation In Vivo and In Vitro after Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Injectable Hydrogels for Spinal Cord Repair: A Focus on Swelling and Intraspinal Pressure. — PubMed · 2016 · Journal Article
- Neuroprotection by Estrogen and Progesterone in Traumatic Brain Injury and Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Neuroprotective and Neurorestorative Processes after Spinal Cord Injury: The Case of the Bulbospinal Respiratory Neurons. — PubMed · 2016 · Journal Article
- Role of KCa3.1 Channels in CNS Diseases: A Concise Review. — PubMed · 2016 · Journal Article
- Serotonin 1A Receptors on Astrocytes as a Potential Target for the Treatment of Parkinson's Disease. — PubMed · 2016 · Journal Article
- Spinal cord injury. From the proof of principle to the therapeutic tool. — PubMed · 2016 · Journal Article
- Targeting the Cholinergic System for Neuroprotection and/or Enhancement of Functional Recovery Following Neurotrauma. — PubMed · 2016 · Journal Article
- Involvement of endoplasmic reticulum stress in the necroptosis of microglia/macrophages after spinal cord injury. — PubMed · 2015 · Journal Article
- Mean Arterial Blood Pressure Correlates with Neurological Recovery after Human Spinal Cord Injury: Analysis of High Frequency Physiologic Data. — PubMed · 2015 · Journal Article
- Tumefactive demyelination of the spinal cord: a case report. — PubMed · 2015 · Case Reports
- Delayed administration of recombinant human erythropoietin reduces apoptosis and inflammation and promotes myelin repair and functional recovery following spinal cord compressive injury in rats. — PubMed · 2015 · Journal Article
- Resveratrol neuroprotection in stroke and traumatic CNS injury. — PubMed · 2015 · Journal Article
- Exercise after spinal cord injury as an agent for neuroprotection, regeneration and rehabilitation. — PubMed · 2015 · Journal Article
- Connexin 43 is an emerging therapeutic target in ischemia/reperfusion injury, cardioprotection and neuroprotection. — PubMed · 2015 · Journal Article
- Management of severe spinal cord injury following hyperbaric exposure. — PubMed · 2015 · Letter
- Rapamycin increases neuronal survival, reduces inflammation and astrocyte proliferation after spinal cord injury. — PubMed · 2015 · Journal Article
- Tolerability and efficacy of erythropoietin (EPO) treatment in traumatic spinal cord injury: a preliminary randomized comparative trial vs. methylprednisolone (MP). — PubMed · 2015 · Clinical Trial, Phase Iii
- Function and Mechanisms of Autophagy in Brain and Spinal Cord Trauma. — PubMed · 2015 · Journal Article
- Therapeutic Hypothermia in Spinal Cord Injury: The Status of Its Use and Open Questions. — PubMed · 2015 · Journal Article
- Hydrogen sulfide protects spinal cord and induces autophagy via miR-30c in a rat model of spinal cord ischemia-reperfusion injury. — PubMed · 2015 · Journal Article
- Acute Spinal Cord Injury. — PubMed · 2015 · Journal Article
- N-acetylcysteine treatment following spinal cord trauma reduces neural tissue damage and improves locomotor function in mice. — PubMed · 2015 · Journal Article
- Preliminary results of using ALAnerv® in subacute motor incomplete paraplegics. — PubMed · 2015 · Controlled Clinical Trial
- Neuroprotective effects of safranal in a rat model of traumatic injury to the spinal cord by anti-apoptotic, anti-inflammatory and edema-attenuating. — PubMed · 2015 · Journal Article
- Predictors of intramedullary lesion expansion rate on MR images of patients with subaxial spinal cord injury. — PubMed · 2015 · Journal Article
- Neuroprotection, Plasticity Manipulation, and Regenerative Strategies to Improve Cardiovascular Function following Spinal Cord Injury. — PubMed · 2015 · Journal Article
- Neuroprotective therapy with granulocyte colony-stimulating factor in acute spinal cord injury: a comparison with high-dose methylprednisolone as a historical control. — PubMed · 2015 · Clinical Trial, Phase I
- Vascular disease of the spine. — PubMed · 2015 · Journal Article
- Concise review: reactive astrocytes and stem cells in spinal cord injury: good guys or bad guys? — PubMed · 2015 · Journal Article
- [Low-dose lipopolysaccharide mediated up-regulation of Nrf2 attenuates inflammatory response in rats with spinal cord injury]. — PubMed · 2015 · English Abstract
- Recent advances in the pharmacologic treatment of spinal cord injury. — PubMed · 2015 · Journal Article
- The use of nanotechnology to improve the neuroprotective effects of adenosine in stroke and spinal cord injury. — PubMed · 2015 · News
- Neonatal brain injury and systemic inflammation: modulation by activated protein C ex vivo. — PubMed · 2015 · Journal Article
- Pharmacological therapy for acute spinal cord injury. — PubMed · 2015 · Journal Article
- Management of thoracolumbar spine fractures with neurologic disorder. — PubMed · 2015 · Journal Article
- Optical stimulation for restoration of motor function after spinal cord injury. — PubMed · 2015 · Journal Article
- Progesterone and allopregnanolone in the central nervous system: response to injury and implication for neuroprotection. — PubMed · 2015 · Journal Article
- Hyperlipidemia and statins affect neurological outcome in lumbar spine injury. — PubMed · 2015 · Journal Article
- Efficacy of some non-conventional herbal medications (sulforaphane, tanshinone IIA, and tetramethylpyrazine) in inducing neuroprotection in comparison with interleukin-10 after spinal cord injury: A meta-analysis. — PubMed · 2015 · Comparative Study
- Immunotherapy strategies for spinal cord injury. — PubMed · 2015 · Journal Article
- Neuroprotective Effect of Simvastatin via Inducing the Autophagy on Spinal Cord Injury in the Rat Model. — PubMed · 2015 · Journal Article
- Roles of kinins in the nervous system. — PubMed · 2015 · Journal Article
- The role of brain-derived neurotrophic factor in bone marrow stromal cell-mediated spinal cord repair. — PubMed · 2015 · Journal Article
- Translating mechanisms of neuroprotection, regeneration, and repair to treatment of spinal cord injury. — PubMed · 2015 · Journal Article
- Valproic acid-mediated neuroprotection and neurogenesis after spinal cord injury: from mechanism to clinical potential. — PubMed · 2015 · Journal Article
- Human NgR-Fc decoy protein via lumbar intrathecal bolus administration enhances recovery from rat spinal cord contusion. — PubMed · 2014 · Journal Article
- Research advances in the application of methylprednisolone in the treatment of acute spinal cord injury. — PubMed · 2014 · Journal Article
- Restoring function after spinal cord injury: towards clinical translation of experimental strategies. — PubMed · 2014 · Journal Article
- The collective therapeutic potential of cerebral ketone metabolism in traumatic brain injury. — PubMed · 2014 · Journal Article
- Early preservation of mitochondrial bioenergetics supports both structural and functional recovery after neurotrauma. — PubMed · 2014 · Journal Article
- Neurotrauma. — PubMed · 2014 · Journal Article
- Toll-like receptors in central nervous system injury and disease: a focus on the spinal cord. — PubMed · 2014 · Journal Article
- Designing drugs that encourage spinal cord injury healing. — PubMed · 2014 · Journal Article
- Erythropoietin: emerging role of erythropoietin in neonatal neuroprotection. — PubMed · 2014 · Journal Article
- Estrogen receptor agonists for attenuation of neuroinflammation and neurodegeneration. — PubMed · 2014 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 6 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1230843 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 | the source found 3744 · this programme has 3744 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])