A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Efficacy of Deferoxamine Mesylate in Serum and Serum-Free Media: Adult Ventral Root Schwann Cell Survival Following Hydrogen Peroxide-Induced Cell Death. — PubMed · 2025 · Journal Article
- Certolizumab enhances spinal cord injury recovery in rats through inhibition of the TNF-α signaling pathway and neuronal apoptosis. — PubMed · 2025 · Journal Article
- Curculigoside Regulates Apoptosis and Oxidative Stress Against Spinal Cord Injury by Modulating the Nrf-2/NQO-1 Signaling Pathway In Vitro and In Vivo. — PubMed · 2025 · Journal Article
- DANCR knockdown alleviates neuroinflammation and functional recovery after spinal cord injury via regulating the ACTN4 / STAT3 axis. — PubMed · 2025 · Journal Article
- Microglia Promote Lymphangiogenesis Around the Spinal Cord Through VEGF-C/VEGFR3-Dependent Autophagy and Polarization After Acute Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Neutrophil membrane-coated multifunctional biomimetic nanoparticles for spinal cord injuries. — PubMed · 2025 · Journal Article
- Resveratrol loaded microglia-derived exosomes attenuate astrogliasis by restoring mitochondrial function to reduce spinal cord injury. — PubMed · 2025 · Journal Article
- FOXO3-induced microRNA-128-3p promotes the progression of spinal cord injury in mice via regulating NLRP3 inflammasome-mediated pyroptosis. — PubMed · 2025 · Journal Article
- Punicalagin inhibits neuron ferroptosis and secondary neuroinflammation to promote spinal cord injury recovery. — PubMed · 2025 · Journal Article
- Methylprednisolone substituted lipid nanoparticles deliver C3 transferase mRNA for combined treatment of spinal cord injury. — PubMed · 2025 · Journal Article
- Automated quantification of axonal and myelin changes in contusion, dislocation, and distraction spinal cord injuries: Insights into targeted remyelination and axonal regeneration. — PubMed · 2025 · Journal Article
- DOCK2 deficiency alleviates neuroinflammation and affords neuroprotection after spinal cord injury. — PubMed · 2025 · Journal Article
- Physicochemical Characterization of Hyaluronic Acid-Methylcellulose Semi-Gels for Mitochondria Transplantation. — PubMed · 2025 · Journal Article
- Transcranial alternating current stimulation inhibits ferroptosis and promotes functional recovery in spinal cord injury via the cGMP-PKG signalling pathway. — PubMed · 2025 · Journal Article
- Evaluation of transcriptomic changes after photobiomodulation in spinal cord injury. — PubMed · 2025 · Journal Article
- GsMTx-4 combined with exercise improves skeletal muscle structure and motor function in rats with spinal cord injury. — PubMed · 2025 · Journal Article
- Gallic acid showed neuroprotection against endoplasmic reticulum stress in rats. — PubMed · 2025 · Journal Article
- Cytosolic phospholipase A2 in infiltrating monocyte derived macrophages does not impair recovery after spinal cord injury in female mice. — PubMed · 2025 · Journal Article
- Microgel-encapsulated tetrandrine nanoparticles promote spinal cord repair by sustaining neuroinflammation inhibition. — PubMed · 2025 · Journal Article
- Cold atmospheric plasma-activated saline alleviates secondary injury post-SCI by inhibiting extracellular matrix remodeling and infiltration of proinflammatory macrophages. — PubMed · 2025 · Journal Article
- Isosteviol Sodium Promotes Neurological Function Recovery in a Model of Spinal Cord Injury in Rats. — PubMed · 2025 · Journal Article
- No Beneficial Effects of the Alfasigma VSL#3 Probiotic Treatment After Cervical Spinal Cord Injury in Rats. — PubMed · 2025 · Journal Article
- Plasmalogens Activate AKT/mTOR Signaling to Attenuate Reactive Oxygen Species Production in Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Resveratrol Upregulates miR-124-3p Expression to Target DAPK1, Regulating the NLRP3/Caspase-1/GSDMD Pathway to Inhibit Pyroptosis and Alleviate Spinal Cord Injury. — PubMed · 2025 · Journal Article
- The role of H3K27 acetylation in oxygen-glucose deprivation-induced spinal cord injury and potential for neuroprotective therapies. — PubMed · 2025 · Journal Article
- IL-18 Blockage Reduces Neuroinflammation and Promotes Functional Recovery in a Mouse Model of Spinal Cord Injury. — PubMed · 2024 · Journal Article
- GsMTx4 Combined with Exercise Exerts Neuroprotective Effects by Regulating Neuronal Autophagy in Rats with Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Berberine attenuates neuronal ferroptosis via the AMPK-NRF2-HO-1-signaling pathway in spinal cord-injured rats. — PubMed · 2024 · Journal Article
- Falcarindiol improves functional recovery and alleviates neuroinflammation after spinal cord injury by inhibiting STAT/MAPK signaling pathways. — PubMed · 2024 · Journal Article
- Metal Ruthenium Complexes Treat Spinal Cord Injury By Alleviating Oxidative Stress Through Interaction With Antioxidant 1 Copper Chaperone Protein. — PubMed · 2024 · Journal Article
- Mirtazapine Improves Locomotor Activity and Attenuates Neuropathic Pain Following Spinal Cord Injury in Rats via Neuroinflammation Modulation. — PubMed · 2024 · Journal Article
- Neuroprotective agents ineffective in mitigating autonomic dysreflexia following experimental spinal cord injury. — PubMed · 2024 · Journal Article
- The Circadian Clock Gene Bmal1 Regulates Microglial Pyroptosis After Spinal Cord Injury via NF-κB/MMP9. — PubMed · 2024 · Journal Article
- TLR3 Knockdown Attenuates Pressure-Induced Neuronal Damage In Vitro. — PubMed · 2024 · Journal Article
- Induction of Neural Differentiation and Protection by a Novel Slow-Release Nanoparticle Estrogen Construct in a Rat Model of Spinal Cord Injury. — PubMed · 2024 · Journal Article
- A critical role for microglia in regulating metabolic homeostasis and neural repair after spinal cord injury. — PubMed · 2024 · Journal Article
- Borneol-Functionalized Macrophage Membrane-Encapsulated Mesoporous Selenium Nanoparticles Loaded with Resveratrol for the Treatment of Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Neurotrophic and synaptic effects of GnRH and/or GH upon motor function after spinal cord injury in rats. — PubMed · 2024 · Journal Article
- Apelin regulates mitochondrial dynamics by inhibiting Mst1-JNK-Drp1 signaling pathway to reduce neuronal apoptosis after spinal cord injury. — PubMed · 2024 · Journal Article
- Mechanism of Gastrodin against neurotoxicity based on network pharmacology, molecular docking and experimental verification. — PubMed · 2024 · Journal Article
- MST2 Acts via AKT Activity to Promote Neurite Outgrowth and Functional Recovery after Spinal Cord Injury in Mice. — PubMed · 2024 · Journal Article
- Neuroprotective macromolecular methylprednisolone prodrug nanomedicine prevents glucocorticoid-induced muscle atrophy and osteoporosis in a rat model of spinal cord injury. — PubMed · 2024 · Journal Article
- Omega-3 polyunsaturated fatty acids alleviate endoplasmic reticulum stress-induced neuroinflammation by protecting against traumatic spinal cord injury through the histone deacetylase 3/ peroxisome proliferator-activated receptor-γ coactivator pathway. — PubMed · 2024 · Journal Article
- Regulating Astrocytes via Short Fibers for Spinal Cord Repair. — PubMed · 2024 · Journal Article
- Bu Shen Huo Xue Formula Provides Neuroprotection Against Spinal Cord Injury by Inhibiting Oxidative Stress by Activating the Nrf2 Signaling Pathway. — PubMed · 2024 · Journal Article
- Ketone Esters Partially and Selectively Rescue Mitochondrial Bioenergetics After Acute Cervical Spinal Cord Injury in Rats: A Time-Course. — PubMed · 2024 · Journal Article
- A spatiotemporal molecular atlas of mouse spinal cord injury identifies a distinct astrocyte subpopulation and therapeutic potential of IGFBP2. — PubMed · 2024 · Journal Article
- Alterations in Endogenous Stem Cell Populations in the Acute Phase of Blast-Induced Spinal Cord Injury. — PubMed · 2024 · Journal Article
- An oil-in-gel type of organohydrogel loaded with methylprednisolone for the treatment of secondary injuries following spinal cord traumas. — PubMed · 2024 · Journal Article
- Beyond expectations: safinamide's unprecedented neuroprotective impact on acute spinal cord injury. — PubMed · 2024 · Journal Article
- Reduction of prolonged excitatory neuron swelling after spinal cord injury improves locomotor recovery in mice. — PubMed · 2024 · Journal Article
- A novel strategy for spinal cord reconstruction via vascularized allogeneic spinal cord transplantation combine spinal cord fusion. — PubMed · 2024 · Journal Article
- Irisflorentin improves functional recovery after spinal cord injury by protecting the blood-spinal cord barrier and promoting axonal growth. — PubMed · 2024 · Journal Article
- Letter to the Editor Regarding "Neuroprotective Effects of Coenzyme Q10 and Ozone Therapy on Experimental Traumatic Spinal Cord Injuries in Rats". — PubMed · 2024 · Letter
- M2 Microglia-derived Exosomes Promote Spinal Cord Injury Recovery in Mice by Alleviating A1 Astrocyte Activation. — PubMed · 2024 · Journal Article
- Mertk Reduces Blood-Spinal Cord Barrier Permeability Through the Rhoa/Rock1/P-MLC Pathway After Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Pharmacologic activation of activating transcription factor 6 contributes to neuronal survival after spinal cord injury in mice. — PubMed · 2024 · Journal Article
- Protective effect of valproic acid on ischemia-reperfusion induced spinal cord injury in a rat model. — PubMed · 2024 · Journal Article
- Protocatechuic aldehyde promotes the functional recovery of spinal cord injury by activating the Wnt/β-catenin signaling pathway. — PubMed · 2024 · Journal Article
- Single-cell RNA sequencing integrated with bulk RNA sequencing analysis reveals the protective effects of lactate-mediated lactylation of microglia-related proteins on spinal cord injury. — PubMed · 2024 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])