A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
The source has not said who or what was studied
- Edaravone Modulates Neuronal GPX4/ACSL4/5-LOX to Promote Recovery After Spinal Cord Injury. — PubMed · 2022 · Journal Article
- The past, present, and future of traumatic spinal cord injury therapies: a review. — PubMed · 2022 · Journal Article
- Melatonin as a Potential Neuroprotectant: Mechanisms in Subarachnoid Hemorrhage-Induced Early Brain Injury. — PubMed · 2022 · Journal Article
- Mechanism Underlying Acupuncture Therapy in Spinal Cord Injury: A Narrative Overview of Preclinical Studies. — PubMed · 2022 · Journal Article
- The Therapeutic Role of Exercise and Probiotics in Stressful Brain Conditions. — PubMed · 2022 · Journal Article
- Krüppel-like factor 7 attenuates hippocampal neuronal injury after traumatic brain injury. — PubMed · 2022 · Journal Article
- Specific microRNAs for Modulation of Autophagy in Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Delving into the recent advancements of spinal cord injury treatment: a review of recent progress. — PubMed · 2022 · Journal Article
- Treatment with Pulsed Extremely Low Frequency Electromagnetic Field (PELF-EMF) Exhibit Anti-Inflammatory and Neuroprotective Effect in Compression Spinal Cord Injury Model. — PubMed · 2022 · Journal Article
- Co-Delivery of Docosahexaenoic Acid and Brain-Derived Neurotropic Factor from Electrospun Aligned Core-Shell Fibrous Membranes in Treatment of Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Lipoxins in the Nervous System: Brighter Prospects for Neuroprotection. — PubMed · 2022 · Journal Article
- Regulatory Role of Mesenchymal Stem Cells on Secondary Inflammation in Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Microglia-Derived Exosomal microRNA-151-3p Enhances Functional Healing After Spinal Cord Injury by Attenuating Neuronal Apoptosis via Regulating the p53/p21/CDK1 Signaling Pathway. — PubMed · 2022 · Journal Article
- Time is spine: A clarion call to action. — PubMed · 2022 · Editorial
- Will Cannabigerol Trigger Neuroregeneration after a Spinal Cord Injury? An In Vitro Answer from NSC-34 Scratch-Injured Cells Transcriptome. — PubMed · 2022 · Journal Article
- Neuroprotective Role of Hypothermia in Acute Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Fully Characterized Mature Human iPS- and NMP-Derived Motor Neurons Thrive Without Neuroprotection in the Spinal Contusion Cavity. — PubMed · 2022 · Journal Article
- Neuroprotective effects of Alda-1 mitigate spinal cord injury in mice: involvement of Alda-1-induced ALDH2 activation-mediated suppression of reactive aldehyde mechanisms. — PubMed · 2022 · Journal Article
- Sodium alginate and naloxone loaded macrophage-derived nanovesicles for the treatment of spinal cord injury. — PubMed · 2022 · Journal Article
- Exosomes derived from olfactory ensheathing cells provided neuroprotection for spinal cord injury by switching the phenotype of macrophages/microglia. — PubMed · 2021 · Journal Article
- Contribution of Brain Processes to Tissue Loss After Spinal Cord Injury: Does a Pain-Induced Rise in Blood Pressure Fuel Hemorrhage? — PubMed · 2021 · Journal Article
- Functional resveratrol-biodegradable manganese doped silica nanoparticles for the spinal cord injury treatment. — PubMed · 2021 · Journal Article
- Hematogenous Macrophages: A New Therapeutic Target for Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Neuroprotection by the Ketogenic Diet: Evidence and Controversies. — PubMed · 2021 · Journal Article
- Trihydroxyethyl Rutin Provides Neuroprotection in Rats With Cervical Spinal Cord Hemi-Contusion. — PubMed · 2021 · Journal Article
- Low-dose metformin treatment in the subacute phase improves the locomotor function of a mouse model of spinal cord injury. — PubMed · 2021 · Journal Article
- The Potential Therapeutic Effects of Agmatine, Methylprednisolone, and Rapamycin on Experimental Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Timeline of Changes in Biomarkers Associated with Spinal Cord Injury-Induced Polyuria. — PubMed · 2021 · Journal Article
- Identification of Circular RNAs Related to Vascular Endothelial Proliferation, Migration, and Angiogenesis After Spinal Cord Injury Using Microarray Analysis in Female Mice. — PubMed · 2021 · Journal Article
- Implications of enolase in the RANKL-mediated osteoclast activity following spinal cord injury. — PubMed · 2021 · Journal Article
- Passive Clearing and 3D Lightsheet Imaging of the Intact and Injured Spinal Cord in Mice. — PubMed · 2021 · Journal Article
- Elucidating the Pivotal Neuroimmunomodulation of Stem Cells in Spinal Cord Injury Repair. — PubMed · 2021 · Journal Article
- Effect of Humic Acid on Oxidative Stress and Neuroprotection in Traumatic Spinal Cord Injury: An Experimental Study. — PubMed · 2021 · Journal Article
- Identification of potential oxidative stress biomarkers for spinal cord injury in erythrocytes using mass spectrometry. — PubMed · 2021 · Journal Article
- Neuroprotective effect of immunomodulatory peptides in rats with traumatic spinal cord injury. — PubMed · 2021 · Journal Article
- The Current Role of Dexmedetomidine as Neuroprotective Agent: An Updated Review. — PubMed · 2021 · Journal Article
- Novel Methods of Necroptosis Inhibition for Spinal Cord Injury Using Translational Research to Limit Secondary Injury and Enhance Endogenous Repair and Regeneration. — PubMed · 2021 · Journal Article
- Involvement of mTOR Pathways in Recovery from Spinal Cord Injury by Modulation of Autophagy and Immune Response. — PubMed · 2021 · Journal Article
- Silencing of Long Noncoding RNA Growth Arrest-Specific 5 Alleviates Neuronal Cell Apoptosis and Inflammatory Responses Through Sponging microRNA-93 to Repress PTEN Expression in Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Silencing TAK1 reduces MAPKs-MMP2/9 expression to reduce inflammation-driven neurohistological disruption post spinal cord injury. — PubMed · 2021 · Journal Article
- Revascularization After Traumatic Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Ganglioside GM1 Targets Astrocytes to Stimulate Cerebral Energy Metabolism. — PubMed · 2021 · Journal Article
- Pannexin-1 Contributes to the Apoptosis of Spinal Neurocytes in Spinal Cord Injury. — PubMed · 2021 · Journal Article
- For Better or for Worse: A Look Into Neutrophils in Traumatic Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Substrate Specificity and Biochemical Characteristics of an Engineered Mammalian Chondroitinase ABC. — PubMed · 2021 · Journal Article
- Functions and Mechanisms of the Voltage-Gated Proton Channel Hv1 in Brain and Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Lysine-specific demethylase 1 inhibition enhances autophagy and attenuates early-stage post-spinal cord injury apoptosis. — PubMed · 2021 · Journal Article
- LncRNA Airsci increases the inflammatory response after spinal cord injury in rats through the nuclear factor kappa B signaling pathway. — PubMed · 2021 · Journal Article
- miR-7b-3p Exerts a Dual Role After Spinal Cord Injury, by Supporting Plasticity and Neuroprotection at Cortical Level. — PubMed · 2021 · Journal Article
- Additive Effects of Environmental Enrichment and Ketamine on Neuropathic Pain Relief by Reducing Glutamatergic Activation in Spinal Cord Injury in Rats. — PubMed · 2021 · Journal Article
- Levetiracetam treatment leads to functional recovery after thoracic or cervical injuries of the spinal cord. — PubMed · 2021 · Journal Article
- Hemodynamic Management of Acute Spinal Cord Injury: A Literature Review. — PubMed · 2021 · Journal Article
- Hydrogel-based local drug delivery strategies for spinal cord repair. — PubMed · 2021 · Journal Article
- Total flavonoids of hawthorn leaves promote motor function recovery via inhibition of apoptosis after spinal cord injury. — PubMed · 2021 · Journal Article
- Rapamycin Preserves Neural Tissue, Promotes Schwann Cell Myelination and Reduces Glial Scar Formation After Hemi-Contusion Spinal Cord Injury in Mice. — PubMed · 2021 · Journal Article
- Resveratrol inhibits LPS-induced apoptosis in VSC4.1 motoneurons through enhancing SIRT1-mediated autophagy. — PubMed · 2021 · Journal Article
- Management of acute spinal cord injury: A summary of the evidence pertaining to the acute management, operative and non-operative management. — PubMed · 2020 · Journal Article
- Pathophysiology, Biomarkers, and Therapeutic Modalities Associated with Skeletal Muscle Loss Following Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Intravenous Administration of Heat Shock-Treated MSCs Can Improve Neuroprotection and Neuroregeneration in Canine Spinal Cord Injury Model. — PubMed · 2020 · Journal Article
- Current Insights Into the Pathology of Canine Intervertebral Disc Extrusion-Induced Spinal Cord Injury. — PubMed · 2020 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 6 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 1230843 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 Collection window: all dates before the end date – 2026-09-17 | matched in this collection walk 3744 · accumulated records across collection walks 3744 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])