A subject this map covers
Neuroprotection
What belongs here
Attempts to stop the second, delayed wave of damage in the first hours and days.
What does not belong here, however close it looks
Restoring function lost months earlier is repair, not neuroprotection.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 1169 records · 1978–2027
- Indexed as work in animals: 1885 records · 1977–2026
- Indexed as laboratory work: 80 records · 1996–2026
- The source has not said who or what was studied: 572 records · 1991–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3706 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Acute Spinal Cord Injury: A Systematic Review Investigating miRNA Families Involved. — PubMed · 2019 · Journal Article
- Squalene-Adenosine Nanoparticles: Ligands of Adenosine Receptors or Adenosine Prodrug? — PubMed · 2019 · Journal Article
- Transplanting Cells for Spinal Cord Repair: Who, What, When, Where and Why? — PubMed · 2019 · Journal Article
- Breathing hydrogen sulfide prevents delayed paraplegia in mice. — PubMed · 2019 · Journal Article
- Aplicaciones terapéuticas por acción de los cannabinoides. — PubMed · 2019 · Journal Article
- Celastrol inhibits microglial pyroptosis and attenuates inflammatory reaction in acute spinal cord injury rats. — PubMed · 2019 · Journal Article
- Erythropoietin as a Neuroprotective Molecule: An Overview of Its Therapeutic Potential in Neurodegenerative Diseases. — PubMed · 2019 · Journal Article
- Management of Spinal Injuries in Polytrauma Patients: An Experience of Tertiary Care Hospital. — PubMed · 2019 · Journal Article
- Pharmacological induction of Heat Shock Protein 70 by celastrol protects motoneurons from excitotoxicity in rat spinal cord in vitro. — PubMed · 2019 · Journal Article
- Spinal cord injury pharmacotherapy: Current research & development and competitive commercial landscape as of 2015. — PubMed · 2019 · Journal Article
- Therapeutic Potential of Wnt-3a in Neurological Recovery after Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Time is spine: a review of translational advances in spinal cord injury. — PubMed · 2018 · Journal Article
- Depletion of astrocytic transglutaminase 2 improves injury outcomes. — PubMed · 2018 · Journal Article
- Wheelchair Breakdowns Are Associated With Pain, Pressure Injuries, Rehospitalization, and Self-Perceived Health in Full-Time Wheelchair Users With Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Cervical and Thoracolumbar Spine Injury Evaluation, Transport, and Surgery in the Deployed Setting. — PubMed · 2018 · Journal Article
- A Review of Clinical Trials in Spinal Cord Injury Including Biomarkers. — PubMed · 2018 · Journal Article
- Cerebrospinal Fluid Biomarkers in Human Spinal Cord Injury from a Phase II Minocycline Trial. — PubMed · 2018 · Clinical Trial, Phase II
- Biomarkers in Spinal Cord Injury: from Prognosis to Treatment. — PubMed · 2018 · Journal Article
- Protective role of β-carotene against oxidative stress and neuroinflammation in a rat model of spinal cord injury. — PubMed · 2018 · Journal Article
- Clinical Trials in Traumatic Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Glial Cells Shape Pathology and Repair After Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Spinal Cord Injury Scarring and Inflammation: Therapies Targeting Glial and Inflammatory Responses. — PubMed · 2018 · Journal Article
- Myelin as an inflammatory mediator: Myelin interactions with complement, macrophages, and microglia in spinal cord injury. — PubMed · 2018 · Journal Article
- Potential immunotherapies for traumatic brain and spinal cord injury. — PubMed · 2018 · Journal Article
- Study protocol for the G-SPIRIT trial: a randomised, placebo-controlled, double-blinded phase III trial of granulocyte colony-stimulating factor-mediated neuroprotection for acute spinal cord injury. — PubMed · 2018 · Clinical Trial Protocol
- Contemporary Single-Center Experience With Prophylactic Cerebrospinal Fluid Drainage for Thoracic Endovascular Aortic Repair in Patients at High Risk for Ischemic Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Immunobiology of spinal cord injuries and potential therapeutic approaches. — PubMed · 2018 · Journal Article
- The Biology of Regeneration Failure and Success After Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Traumatic Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Stress-Activated Protein Kinases in Spinal Cord Injury: Focus on Roles of p38. — PubMed · 2018 · Journal Article
- Extragonadal germ cell tumor of the posterior mediastinum in a child complicated with spinal cord compression: a case report. — PubMed · 2018 · Case Reports
- Therapeutic potential of spinal GLP-1 receptor signaling. — PubMed · 2018 · Journal Article
- Growth Hormone (GH) and Gonadotropin-Releasing Hormone (GnRH) in the Central Nervous System: A Potential Neurological Combinatory Therapy? — PubMed · 2018 · Journal Article
- Alternative Routes of Administration of the Neuroprotective Pituitary Adenylate Cyclase Activating Polypeptide. — PubMed · 2018 · Journal Article
- Astrocyte Neuroprotection and Dehydroepiandrosterone. — PubMed · 2018 · Journal Article
- Biomaterial Approaches to Modulate Reactive Astroglial Response. — PubMed · 2018 · Journal Article
- Characterization of neural stem cells modified with hypoxia/neuron-specific VEGF expression system for spinal cord injury. — PubMed · 2018 · Journal Article
- Hypothermia Used in Medical Applications for Brain and Spinal Cord Injury Patients. — PubMed · 2018 · Journal Article
- Lycium Barbarum Polysaccharides Alleviates Oxidative Damage Induced by H2O2 Through Down-Regulating MicroRNA-194 in PC-12 and SH-SY5Y Cells. — PubMed · 2018 · Journal Article The source marks this record as retracted.
- Neuroprotective effects of high-dose human albumin against traumatic spinal cord injury in rats. — PubMed · 2018 · Journal Article
- Effect of the combined treatment of albumin with plasma synthesised pyrrole polymers on motor recovery after traumatic spinal cord injury in rats. — PubMed · 2017 · Journal Article
- Lessons learned from administration of high-dose methylprednisolone sodium succinate for acute pediatric spinal cord injuries. — PubMed · 2017 · Journal Article
- Mitochondrial-Based Therapeutics for the Treatment of Spinal Cord Injury: Mitochondrial Biogenesis as a Potential Pharmacological Target. — PubMed · 2017 · Journal Article
- Non-coding RNAs and neuroprotection after acute CNS injuries. — PubMed · 2017 · Journal Article
- Steroid and Xenobiotic Receptor Signalling in Apoptosis and Autophagy of the Nervous System. — PubMed · 2017 · Journal Article
- Assessment and management of acute spinal cord injury: From point of injury to rehabilitation. — PubMed · 2017 · Case Reports
- Granulocyte Colony-Stimulating Factor (G-CSF) for the Treatment of Spinal Cord Injury. — PubMed · 2017 · Journal Article
- The impact of blood pressure management after spinal cord injury: a systematic review of the literature. — PubMed · 2017 · Journal Article
- Update on critical care for acute spinal cord injury in the setting of polytrauma. — PubMed · 2017 · Journal Article
- Transcriptome Analysis Reveals Neuroprotective aspects of Human Reactive Astrocytes induced by Interleukin 1β. — PubMed · 2017 · Journal Article
- Tetramethylpyrazine alleviates neural apoptosis in injured spinal cord via the downregulation of miR-214-3p. — PubMed · 2017 · Journal Article
- Design and optimization of PLGA microparticles for controlled and local delivery of Neuregulin-1 in traumatic spinal cord injury. — PubMed · 2017 · Journal Article
- Therapeutic potential of agmatine for CNS disorders. — PubMed · 2017 · Journal Article
- Neurosurgical Emergencies in Sport. — PubMed · 2017 · Journal Article
- Pathophysiology, mechanisms and applications of mesenchymal stem cells for the treatment of spinal cord injury. — PubMed · 2017 · Journal Article
- Anterior cervical distraction and screw elevating-pulling reduction for traumatic cervical spine fractures and dislocations: A retrospective analysis of 86 cases. — PubMed · 2017 · Journal Article
- An update on application of nanotechnology and stem cells in spinal cord injury regeneration. — PubMed · 2017 · Journal Article
- Hypoxic conditioning and the central nervous system: A new therapeutic opportunity for brain and spinal cord injuries? — PubMed · 2017 · Journal Article
- Traumatic spinal cord injury: current concepts and treatment update. — PubMed · 2017 · Journal Article
- Update on traumatic acute spinal cord injury. Part 2. — PubMed · 2017 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 6 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 1230843 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 | the source found 3744 · this programme has 3744 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroprotection" OR "secondary injury") - Crossref
spinal cord injury neuroprotection secondary injury - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neuroprotection"[MeSH Terms] OR "Neuroprotective Agents"[MeSH Terms] OR "neuroprotection"[Title/Abstract] OR "secondary injury"[Title/Abstract])