A subject this map covers
Viral vector delivery
Part of: Gene therapy
What belongs here
Gene delivery by viral vector to the cord or to the neurons that reach it.
What does not belong here, however close it looks
Non-viral delivery — nanoparticles, electroporation — has its own concepts.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 92 records · 1995–2026
- Indexed as work in animals: 246 records · 1998–2026
- Indexed as laboratory work: 13 records · 1997–2021
- The source has not said who or what was studied: 68 records · 1996–2026
- No clinical trial on this subject is registered for spinal cord injury.
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
419 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Treatment of spinal injury muscle spasticity by spinal subpial AAV9-GAD65/VGAT delivery: An efficacy and safety study in rat, pig, and NHP. — PubMed · 2026 · Journal Article
- Optimized genetic tracers for viral mediated neuronal projection mapping. — PubMed · 2026 · Journal Article
- AAV vectors: an emerging strategy for chronic pain management. — PubMed · 2026 · Journal Article
- Neuronal HDAC3 knockdown promotes propriospinal detour pathway formation and locomotor recovery in a mouse model of spinal cord injury. — PubMed · 2025 · Journal Article
- Present insights into the progress in gene therapy delivery systems for central nervous system diseases. — PubMed · 2025 · Journal Article
- MCT1-mediated endothelial cell lactate shuttle as a target for promoting axon regeneration after spinal cord injury. — PubMed · 2024 · Journal Article
- BMP7 Attenuates Neuroinflammation after Spinal Cord Injury by Suppressing the Microglia Activation and Inducing Microglial Polarization Via the STAT3 Pathway. — PubMed · 2023 · Journal Article
- Delayed inhibition of collagen deposition by targeting bone morphogenetic protein 1 promotes recovery after spinal cord injury. — PubMed · 2023 · Journal Article
- Therapeutic Potential of Combinative shRNA-Encoded Lentivirus-Mediated Gene Silencing to Accelerate Somatosensory Recovery After Spinal Cord Trauma. — PubMed · 2023 · Journal Article
- Synaptogenic gene therapy with FGF22 improves circuit plasticity and functional recovery following spinal cord injury. — PubMed · 2023 · Journal Article
- Proper wiring of newborn neurons to control bladder function after complete spinal cord injury. — PubMed · 2023 · Journal Article
- Obtaining a New Gene-Cell Construct Based on Transduced Olfactory Ensheathing Cells for the Treatment of Spinal Cord Injuries. — PubMed · 2022 · Journal Article
- The use of viral vectors to promote repair after spinal cord injury. — PubMed · 2022 · Journal Article
- Effect of different expression patterns of HAX-1 on the proliferation and apoptosis of human astrocyte. — PubMed · 2022 · Journal Article
- Viral tools for mapping and modulating neural networks after spinal cord injury. — PubMed · 2022 · Journal Article
- Harnessing rAAV-retro for gene manipulations in multiple pathways that are interrupted after spinal cord injury. — PubMed · 2022 · Journal Article
- Exploring propriospinal neuron-mediated neural circuit plasticity using recombinant viruses after spinal cord injury. — PubMed · 2022 · Journal Article
- Peripherally delivered Adeno-associated viral vectors for spinal cord injury repair. — PubMed · 2022 · Journal Article
- Gene Therapy Approach with an Emphasis on Growth Factors: Theoretical and Clinical Outcomes in Neurodegenerative Diseases. — PubMed · 2022 · Journal Article
- Chemogenetic stimulation of proprioceptors remodels lumbar interneuron excitability and promotes motor recovery after SCI. — PubMed · 2021 · Journal Article
- Targeting the Corticospinal Tract in Neonatal Rats with a Double-Viral Vector using Combined Brain and Spine Surgery. — PubMed · 2021 · Journal Article
- Improvement of Rat Spinal Cord Injury Following Lentiviral Vector-Transduced Neural Stem/Progenitor Cells Derived from Human Epileptic Brain Tissue Transplantation with a Self-assembling Peptide Scaffold. — PubMed · 2021 · Journal Article
- LncRNA MIAT activates vascular endothelial growth factor A through RAD21 to promote nerve injury repair in acute spinal cord injury. — PubMed · 2021 · Journal Article
- Transneuronal delivery of hyper-interleukin-6 enables functional recovery after severe spinal cord injury in mice. — PubMed · 2021 · Journal Article
- Epidural Stimulation Combined with Triple Gene Therapy for Spinal Cord Injury Treatment. — PubMed · 2020 · Journal Article
- Transcriptional repression of PTEN in neural cells using CRISPR/dCas9 epigenetic editing. — PubMed · 2020 · Journal Article
- Upregulation of microRNA-200a in bone marrow mesenchymal stem cells enhances the repair of spinal cord injury in rats by reducing oxidative stress and regulating Keap1/Nrf2 pathway. — PubMed · 2020 · Journal Article
- Overexpression of Rictor in the injured spinal cord promotes functional recovery in a rat model of spinal cord injury. — PubMed · 2020 · Journal Article
- The repair and autophagy mechanisms of hypoxia-regulated bFGF-modified primary embryonic neural stem cells in spinal cord injury. — PubMed · 2020 · Journal Article
- Viral Vector-Mediated Gene Transfer of Glutamic Acid Decarboxylase for Chronic Pain Treatment: A Literature Review. — PubMed · 2020 · Journal Article
- The adeno-associated virus rh10 vector is an effective gene transfer system for chronic spinal cord injury. — PubMed · 2019 · Journal Article
- Neuropilin-1-mediated pruning of corticospinal tract fibers is required for motor recovery after spinal cord injury. — PubMed · 2019 · Journal Article
- HIF-1α promotes bone marrow stromal cell migration to the injury site and enhances functional recovery after spinal cord injury in rats. — PubMed · 2018 · Journal Article
- Non-viral-mediated suppression of AMIGO3 promotes disinhibited NT3-mediated regeneration of spinal cord dorsal column axons. — PubMed · 2018 · Journal Article
- Lentivirus-mediated silencing of the PTC1 and PTC2 genes promotes recovery from spinal cord injury by activating the Hedgehog signaling pathway in a rat model. — PubMed · 2017 · Journal Article
- Post-spinal cord injury astrocyte-mediated functional recovery in rats after intraspinal injection of the recombinant adenoviral vectors Ad5-VEGF and Ad5-ANG. — PubMed · 2017 · Journal Article
- Evaluation of direct and cell-mediated triple-gene therapy in spinal cord injury in rats. — PubMed · 2017 · Journal Article
- A pilot study of cell-mediated gene therapy for spinal cord injury in mini pigs. — PubMed · 2017 · Journal Article
- Fail-Safe System against Potential Tumorigenicity after Transplantation of iPSC Derivatives. — PubMed · 2017 · Journal Article
- Combined chondroitinase and KLF7 expression reduce net retraction of sensory and CST axons from sites of spinal injury. — PubMed · 2017 · Journal Article
- Human neural progenitors derived from integration-free iPSCs for SCI therapy. — PubMed · 2017 · Journal Article
- Electrophysiological, Morphological, and Ultrastructural Features of the Injured Spinal Cord Tissue after Transplantation of Human Umbilical Cord Blood Mononuclear Cells Genetically Modified with the VEGF and GDNF Genes. — PubMed · 2017 · Journal Article
- Gene therapy and respiratory neuroplasticity. — PubMed · 2017 · Journal Article
- Suppression of MicroRNA-383 Enhances Therapeutic Potential of Human Bone-Marrow-Derived Mesenchymal Stem Cells in Treating Spinal Cord Injury via GDNF. — PubMed · 2017 · Journal Article
- Canine olfactory ensheathing cells from the olfactory mucosa can be engineered to produce active chondroitinase ABC. — PubMed · 2016 · Journal Article
- Stereotactic injection of shrna GSK-3β-AAV promotes axonal regeneration after spinal cord injury. — PubMed · 2016 · Journal Article
- Spinal cord injury. From the proof of principle to the therapeutic tool. — PubMed · 2016 · Journal Article
- Sponge-mediated lentivirus delivery to acute and chronic spinal cord injuries. — PubMed · 2015 · Journal Article
- Viral vectors encoding endomorphins and serine histogranin attenuate neuropathic pain symptoms after spinal cord injury in rats. — PubMed · 2015 · Journal Article
- Spinal cord injury and the neuron-intrinsic regeneration-associated gene program. — PubMed · 2014 · Journal Article
- Adenoviral-mediated glial cell line-derived neurotrophic factor gene transfer has a protective effect on sciatic nerve following constriction-induced spinal cord injury. — PubMed · 2014 · Journal Article
- Enhanced neuroprotection and improved motor function in traumatized rat spinal cords by rAAV2-mediated glial-derived neurotrophic factor combined with early rehabilitation training. — PubMed · 2014 · Journal Article
- Efficient gene expression from integration-deficient lentiviral vectors in the spinal cord. — PubMed · 2013 · Journal Article
- Targeted delivery of TrkB receptor to phrenic motoneurons enhances functional recovery of rhythmic phrenic activity after cervical spinal hemisection. — PubMed · 2013 · Journal Article
- Usage of plasmid vector carrying vegf and fgf2 genes after spinal cord injury in rats. — PubMed · 2013 · Journal Article
- [Construction and identification of recombinant adeno-associated virus shuttle vector expressing nerve growth factor beta gene]. — PubMed · 2012 · English Abstract
- Corticospinal tract transduction: a comparison of seven adeno-associated viral vector serotypes and a non-integrating lentiviral vector. — PubMed · 2012 · Comparative Study
- Differential effects of brain-derived neurotrophic factor and neurotrophin-3 on hindlimb function in paraplegic rats. — PubMed · 2012 · Journal Article
- Transforming growth factor α transforms astrocytes to a growth-supportive phenotype after spinal cord injury. — PubMed · 2011 · Journal Article
- Lentiviral vectors express chondroitinase ABC in cortical projections and promote sprouting of injured corticospinal axons. — PubMed · 2011 · Comparative Study
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 0 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-17 | the source found 2898038 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-09-17 | the source found 393 · this programme has 393 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("adeno-associated virus" OR "AAV vector" OR "lentiviral vector") - Crossref
spinal cord injury adeno-associated virus AAV vector - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Dependovirus"[MeSH Terms] OR "Genetic Vectors"[MeSH Terms] OR "adeno-associated virus"[Title/Abstract] OR "AAV vector"[Title/Abstract] OR "lentiviral vector"[Title/Abstract])