A subject this map covers
Antisense oligonucleotides and RNA therapy
Part of: Gene therapy
What belongs here
RNA molecules or their analogues given to change how a gene works after injury.
What does not belong here, however close it looks
MicroRNA as a biomarker without intervention is diagnostics, not therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 262 records · 1997–2026
- Indexed as work in animals: 612 records · 2000–2026
- Indexed as laboratory work: 28 records · 2007–2024
- The source has not said who or what was studied: 173 records · 1977–2026
- No clinical trial on this subject is registered for spinal cord injury.
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1075 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Differential Expression Profiles and Functional Predication of Circular Ribonucleic Acid in Traumatic Spinal Cord Injury of Rats. — PubMed · 2019 · Journal Article
- Inhibition of NOX2 signaling limits pain-related behavior and improves motor function in male mice after spinal cord injury: Participation of IL-10/miR-155 pathways. — PubMed · 2019 · Journal Article
- Let-7 participates in the regulation of inflammatory response in spinal cord injury through PI3K/Akt signaling pathway. — PubMed · 2019 · Journal Article
- MiR-543-5p inhibits inflammation and promotes nerve regeneration through inactivation of the NF-κB in rats after spinal cord injury. — PubMed · 2019 · Journal Article
- Docosahexaenoic acid reduces microglia phagocytic activity via miR-124 and induces neuroprotection in rodent models of spinal cord contusion injury. — PubMed · 2019 · Journal Article
- Mesenchymal stem cell derived EVs mediate neuroprotection after spinal cord injury in rats via the microRNA-21-5p/FasL gene axis. — PubMed · 2019 · Journal Article
- FBXW5 reduction alleviates spinal cord injury (SCI) by blocking microglia activity: A mechanism involving p38 and JNK. — PubMed · 2019 · Journal Article
- Triptolide Suppressed the Microglia Activation to Improve Spinal Cord Injury Through miR-96/IKKβ/NF-κB Pathway. — PubMed · 2019 · Journal Article
- A Causal Relationship in Spinal Cord Injury Rat Model Between Microglia Activation and EGFR/MAPK Detected by Overexpression of MicroRNA-325-3p. — PubMed · 2019 · Journal Article
- Effects of MiR-146a on repair and inflammation in rats with spinal cord injury through the TLR/NF-κB signaling pathway. — PubMed · 2019 · Journal Article
- Inhibition of MSK1 Promotes Inflammation and Apoptosis and Inhibits Functional Recovery After Spinal Cord Injury. — PubMed · 2019 · Journal Article
- MicroRNA-30c abrogation protects against spinal cord ischemia reperfusion injury through modulating SIRT1. — PubMed · 2019 · Journal Article
- MiR-29 regulates retinopathy in diabetic mice via the AMPK signaling pathway. — PubMed · 2019 · Journal Article
- Identification of noncoding RNA expression profiles and regulatory interaction networks following traumatic spinal cord injury by sequence analysis. — PubMed · 2019 · Journal Article
- Expression of miR-210 mediated by adeno-associated virus performed neuroprotective effects on a rat model of acute spinal cord injury. — PubMed · 2019 · Journal Article
- MicroRNA‑124 improves functional recovery and suppresses Bax‑dependent apoptosis in rats following spinal cord injury. — PubMed · 2019 · Journal Article
- MicroRNA-448 inhibits the regeneration of spinal cord injury through PI3K/AKT/Bcl-2 axis. — PubMed · 2019 · Comparative Study
- MiR-543-3p promotes locomotor function recovery after spinal cord injury by inhibiting the expression of tumor necrosis factor superfamily member 15 in rats. — PubMed · 2019 · Comparative Study
- miR-940 promotes spinal cord injury recovery by inhibiting TLR4/NF-κB pathway-mediated inflammation. — PubMed · 2019 · Journal Article
- Sinomenine Attenuates Traumatic Spinal Cord Injury by Suppressing Oxidative Stress and Inflammation via Nrf2 Pathway. — PubMed · 2019 · Journal Article
- SIRT1 inhibits apoptosis in in vivo and in vitro models of spinal cord injury via microRNA-494. — PubMed · 2019 · Journal Article
- Sorafenib promotes sensory conduction function recovery via miR-142-3p/AC9/cAMP axis post dorsal column injury. — PubMed · 2019 · Journal Article
- MicroRNA-362-3p attenuates motor deficit following spinal cord injury via targeting paired box gene 2. — PubMed · 2019 · Journal Article
- Abdominal Aortic Transplantation of Bone Marrow Mesenchymal Stem Cells Regulates the Expression of Ciliary Neurotrophic Factor and Inflammatory Cytokines in a Rat Model of Spinal Cord Ischemia-Reperfusion Injury. — PubMed · 2019 · Journal Article
- Role of Na(V)1.6 and Na(V)β4 Sodium Channel Subunits in a Rat Model of Low Back Pain Induced by Compression of the Dorsal Root Ganglia. — PubMed · 2019 · Journal Article
- Inhibition of miR-214-5p attenuates inflammatory chemotaxis and nerve regeneration obstruction after spinal cord injury in rats. — PubMed · 2019 · Journal Article
- MicroRNA-219 Inhibits Proliferation and Induces Differentiation of Oligodendrocyte Precursor Cells after Contusion Spinal Cord Injury in Rats. — PubMed · 2019 · Journal Article
- Hypoxia preconditioning promotes bone marrow mesenchymal stem cells survival by inducing HIF-1α in injured neuronal cells derived exosomes culture system. — PubMed · 2019 · Journal Article
- Scaffold-Mediated Sustained, Non-viral Delivery of miR-219/miR-338 Promotes CNS Remyelination. — PubMed · 2019 · Journal Article
- Carbon monoxide releasing molecule-3 alleviates neuron death after spinal cord injury via inflammasome regulation. — PubMed · 2019 · Journal Article
- The protective effect of microRNA-21 in neurons after spinal cord injury. — PubMed · 2019 · Journal Article
- Resveratrol alleviates lipopolysaccharide-induced inflammation in PC-12 cells and in rat model. — PubMed · 2019 · Journal Article
- Polydatin attenuates spinal cord injury in rats by inhibiting oxidative stress and microglia apoptosis via Nrf2/HO-1 pathway. — PubMed · 2019 · Journal Article
- Inhibition of TREM1 reduces inflammation and oxidative stress after spinal cord injury (SCI) associated with HO-1 expressions. — PubMed · 2019 · Journal Article
- MiR-20a Plays a Key Regulatory Role in the Repair of Spinal Cord Dorsal Column Lesion via PDZ-RhoGEF/RhoA/GAP43 Axis in Rat. — PubMed · 2019 · Journal Article
- MiR-21 inhibitor improves locomotor function recovery by inhibiting IL-6R/JAK-STAT pathway-mediated inflammation after spinal cord injury in model of rat. — PubMed · 2019 · Journal Article
- MiR-494 alleviates lipopolysaccharide (LPS)-induced autophagy and apoptosis in PC-12 cells by targeting IL-13. — PubMed · 2019 · Journal Article
- Retracted: MiR-34a Inhibits Spinal Cord Injury and Blocks Spinal Cord Neuron Apoptosis by Activating Phatidylinositol 3-kinase (PI3K)/AKT Pathway Through Targeting CD47. — PubMed · 2019 · Journal Article The source marks this record as retracted.
- RETRACTED: Tanshinone IIA alleviates oxidative damage after spinal cord injury in vitro and in vivo through up-regulating miR-124. — PubMed · 2019 · Journal Article The source marks this record as retracted.
- Downregulation of long noncoding RNA Sox2ot protects PC-12 cells from hydrogen peroxide-induced injury in spinal cord injury via regulating the miR-211-myeloid cell leukemia-1 isoform2 axis. — PubMed · 2018 · Journal Article The source marks this record as retracted.
- RETRACTED: Angelica polysaccharide protects PC-12 cells from lipopolysaccharide-induced injury via down-regulating microRNA-223. — PubMed · 2018 · Journal Article The source marks this record as retracted.
- Translocation Associated Membrane Protein 1 Contributes to Chronic Constriction Injury-Induced Neuropathic Pain in the Dorsal Root Ganglion and Spinal Cord in Rats. — PubMed · 2018 · Journal Article
- A Potential Competitive Endogenous RNA Pathway Involved in Chronic Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Lentivirus-Mediated Overexpression of miR-29a Promotes Axonal Regeneration and Functional Recovery in Experimental Spinal Cord Injury via PI3K/Akt/mTOR Pathway. — PubMed · 2018 · Journal Article
- Mulberrin (Mul) reduces spinal cord injury (SCI)-induced apoptosis, inflammation and oxidative stress in rats via miroRNA-337 by targeting Nrf-2. — PubMed · 2018 · Journal Article
- Decreased expression of LATS1 correlates with astrogliosis after spinal cord injury. — PubMed · 2018 · Journal Article
- MicroRNA-210 promotes spinal cord injury recovery by inhibiting inflammation via the JAK-STAT pathway. — PubMed · 2018 · Journal Article
- MiR-155 deletion reduces ischemia-induced paralysis in an aortic aneurysm repair mouse model: Utility of immunohistochemistry and histopathology in understanding etiology of spinal cord paralysis. — PubMed · 2018 · Journal Article
- Up-regulation of TNF Receptor-associated Factor 7 after spinal cord injury in rats may have implication for neuronal apoptosis. — PubMed · 2018 · Journal Article
- Silencing of PHLPP1 promotes neuronal apoptosis and inhibits functional recovery after spinal cord injury in mice. — PubMed · 2018 · Journal Article
- Overexpression of TUSC7 inhibits the inflammation caused by microglia activation via regulating miR-449a/PPAR-γ. — PubMed · 2018 · Journal Article
- Macrophage migration inhibitory factor facilitates production of CCL5 in astrocytes following rat spinal cord injury. — PubMed · 2018 · Journal Article
- MicroRNA-21a-5p promotes fibrosis in spinal fibroblasts after mechanical trauma. — PubMed · 2018 · Journal Article
- Overexpression of miR-381-3p promotes the recovery of spinal cord injury. — PubMed · 2018 · Journal Article
- Diosgenin Glucoside Protects against Spinal Cord Injury by Regulating Autophagy and Alleviating Apoptosis. — PubMed · 2018 · Journal Article
- Knockdown of MicroRNA-21 Promotes Neurological Recovery After Acute Spinal Cord Injury. — PubMed · 2018 · Journal Article
- MicroRNA‑381/Hes1 is a potential therapeutic target for spinal cord injury. — PubMed · 2018 · Journal Article
- Resolvin D1 Halts Remote Neuroinflammation and Improves Functional Recovery after Focal Brain Damage Via ALX/FPR2 Receptor-Regulated MicroRNAs. — PubMed · 2018 · Journal Article
- Upregulation of miR-199a-5p Protects Spinal Cord Against Ischemia/Reperfusion-Induced Injury via Downregulation of ECE1 in Rat. — PubMed · 2018 · Journal Article
- [Effect of lentivirus-mediated small interfering RNA on mitogen- and stress-activated protein kinase 1 in spinal cord injury of rats]. — PubMed · 2018 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 0 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 854026 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-05 | the source found 2 · this programme has 1046 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("antisense oligonucleotide" OR "siRNA" OR "microRNA") - Crossref
spinal cord injury antisense oligonucleotide siRNA - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Oligonucleotides, Antisense"[MeSH Terms] OR "RNA, Small Interfering"[MeSH Terms] OR "MicroRNAs"[MeSH Terms] OR "antisense oligonucleotide"[Title/Abstract] OR "siRNA"[Title/Abstract] OR "microRNA"[Title/Abstract])