A subject this map covers
Antisense oligonucleotides and RNA therapy
Part of: Gene therapy
What belongs here
RNA molecules or their analogues given to change how a gene works after injury.
What does not belong here, however close it looks
MicroRNA as a biomarker without intervention is diagnostics, not therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 262 records · 1997–2026
- Indexed as work in animals: 612 records · 2000–2026
- Indexed as laboratory work: 28 records · 2007–2024
- The source has not said who or what was studied: 173 records · 1977–2026
- No clinical trial on this subject is registered for spinal cord injury.
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1075 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Therapeutic applications of zebrafish (Danio rerio) miRNAs linked with human diseases: A prospective review. — PubMed · 2018 · Journal Article
- MicroRNA-490-3p inhibits inflammation and apoptosis induced by spinal cord injury via targeting MK2. — PubMed · 2018 · Journal Article
- Zhenbao Pill reduces Treg cell proportion in acute spinal cord injury rats by regulating TUG1/miR-214/HSP27 axis. — PubMed · 2018 · Journal Article
- Bioinformatic Analysis of Potential Biomarkers for Spinal Cord-injured Patients with Intractable Neuropathic Pain. — PubMed · 2018 · Journal Article
- Over-expressed miR-27a-3p inhibits inflammatory response to spinal cord injury by decreasing TLR4. — PubMed · 2018 · Journal Article
- Non-viral-mediated suppression of AMIGO3 promotes disinhibited NT3-mediated regeneration of spinal cord dorsal column axons. — PubMed · 2018 · Journal Article
- MicroRNA-based therapeutics in central nervous system injuries. — PubMed · 2018 · Journal Article
- Protective effect of epigenetic silencing of CyclinD1 against spinal cord injury using bone marrow-derived mesenchymal stem cells in rats. — PubMed · 2018 · Journal Article
- Emerging targets for reprograming the immune response to promote repair and recovery of function after spinal cord injury. — PubMed · 2018 · Journal Article
- MicroRNAs: Roles in Regulating Neuroinflammation. — PubMed · 2018 · Journal Article
- MiR-137 inhibited inflammatory response and apoptosis after spinal cord injury via targeting of MK2. — PubMed · 2018 · Journal Article
- Zhenbao pill protects against acute spinal cord injury via miR-146a-5p regulating the expression of GPR17. — PubMed · 2018 · Journal Article
- Comprehensive Effects of Suppression of MicroRNA-383 in Human Bone-Marrow-Derived Mesenchymal Stem Cells on Treating Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Lycium Barbarum Polysaccharides Alleviates Oxidative Damage Induced by H2O2 Through Down-Regulating MicroRNA-194 in PC-12 and SH-SY5Y Cells. — PubMed · 2018 · Journal Article The source marks this record as retracted.
- Non-coding RNAs and neuroprotection after acute CNS injuries. — PubMed · 2017 · Journal Article
- The role of the miR-99b-5p/mTOR signaling pathway in neuroregeneration in mice following spinal cord injury. — PubMed · 2017 · Journal Article
- The roles of microRNAs in spinal cord injury. — PubMed · 2017 · Journal Article
- Zhenbao Pill reduces the percentage of Treg cells by inducing HSP27 expression. — PubMed · 2017 · Journal Article
- Functional integration of complex miRNA networks in central and peripheral lesion and axonal regeneration. — PubMed · 2017 · Journal Article
- Update on critical care for acute spinal cord injury in the setting of polytrauma. — PubMed · 2017 · Journal Article
- Tetramethylpyrazine alleviates neural apoptosis in injured spinal cord via the downregulation of miR-214-3p. — PubMed · 2017 · Journal Article
- MicroRNA-211/BDNF axis regulates LPS-induced proliferation of normal human astrocyte through PI3K/AKT pathway. — PubMed · 2017 · Journal Article
- Lentiviral Delivery of miR-133b Improves Functional Recovery After Spinal Cord Injury in Mice. — PubMed · 2017 · Journal Article
- The role of the miR-17-92 cluster in neurogenesis and angiogenesis in the central nervous system of adults. — PubMed · 2017 · Journal Article
- MiR-140/BDNF axis regulates normal human astrocyte proliferation and LPS-induced IL-6 and TNF-α secretion. — PubMed · 2017 · Journal Article
- IL-1β-induces NF-κB and upregulates microRNA-372 to inhibit spinal cord injury recovery. — PubMed · 2017 · Journal Article
- MicroRNA-489-3p inhibits neurite growth by regulating PI3K/AKT pathway in spinal cord injury. — PubMed · 2017 · Journal Article
- Suppression of MicroRNA-383 Enhances Therapeutic Potential of Human Bone-Marrow-Derived Mesenchymal Stem Cells in Treating Spinal Cord Injury via GDNF. — PubMed · 2017 · Journal Article
- The Signature of MicroRNA Dysregulation in Muscle Paralyzed by Spinal Cord Injury Includes Downregulation of MicroRNAs that Target Myostatin Signaling. — PubMed · 2016 · Journal Article
- Literature Research Regarding miRNAs' Expression in the Assessment and Evaluation of the Critically Ill Polytrauma Patient with Traumatic Brain and Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Regulation of Caveolin-1 and Junction Proteins by bFGF Contributes to the Integrity of Blood-Spinal Cord Barrier and Functional Recovery. — PubMed · 2016 · Journal Article
- Stereotactic injection of shrna GSK-3β-AAV promotes axonal regeneration after spinal cord injury. — PubMed · 2016 · Journal Article
- Therapeutical Strategies for Spinal Cord Injury and a Promising Autologous Astrocyte-Based Therapy Using Efficient Reprogramming Techniques. — PubMed · 2016 · Journal Article
- Epidermal growth factor attenuates blood-spinal cord barrier disruption via PI3K/Akt/Rac1 pathway after acute spinal cord injury. — PubMed · 2016 · Journal Article
- Functional recovery after cervical spinal cord injury: Role of neurotrophin and glutamatergic signaling in phrenic motoneurons. — PubMed · 2016 · Journal Article
- Chitosan polyplex mediated delivery of miRNA-124 reduces activation of microglial cells in vitro and in rat models of spinal cord injury. — PubMed · 2016 · Journal Article
- Advances in Biomarkers in Critical Ill Polytrauma Patients. — PubMed · 2016 · Journal Article
- Exosome-mediated inflammasome signaling after central nervous system injury. — PubMed · 2016 · Journal Article
- Extrinsic and Intrinsic Regulation of Axon Regeneration by MicroRNAs after Spinal Cord Injury. — PubMed · 2016 · Journal Article
- MicroRNAs: Key Players in Microglia and Astrocyte Mediated Inflammation in CNS Pathologies. — PubMed · 2016 · Journal Article
- Spinal cord injury. From the proof of principle to the therapeutic tool. — PubMed · 2016 · Journal Article
- Exercise after spinal cord injury as an agent for neuroprotection, regeneration and rehabilitation. — PubMed · 2015 · Journal Article
- [Micro RNA and its role in the pathophysiology of spinal cord injury - a further step towards neuroregenerative medicine]. — PubMed · 2015 · English Abstract
- miR-142-3p is a Potential Therapeutic Target for Sensory Function Recovery of Spinal Cord Injury. — PubMed · 2015 · Journal Article
- Rational Polypharmacology: Systematically Identifying and Engaging Multiple Drug Targets To Promote Axon Growth. — PubMed · 2015 · Journal Article
- MicroRNA: Key regulators of oligodendrocyte development and pathobiology. — PubMed · 2015 · Journal Article
- Hydrogen sulfide protects spinal cord and induces autophagy via miR-30c in a rat model of spinal cord ischemia-reperfusion injury. — PubMed · 2015 · Journal Article
- Combinatorial effects of miR-20a and miR-29b on neuronal apoptosis induced by spinal cord injury. — PubMed · 2015 · Journal Article
- Identification of disease-related miRNAs based on co-expression network in spinal cord injury. — PubMed · 2015 · Journal Article
- Increased HDAC3 and decreased miRNA-130a expression in PBMCs through recruitment HDAC3 in patients with spinal cord injuries. — PubMed · 2015 · Journal Article
- Emerging roles of microRNAs in chronic pain. — PubMed · 2014 · Journal Article
- Expression of suppressor of cytokine signaling-3 (SOCS3) and its role in neuronal death after complete spinal cord injury. — PubMed · 2014 · Journal Article
- Identifying the role of microRNAs in spinal cord injury. — PubMed · 2014 · Journal Article
- microRNAs in spinal cord injury: potential roles and therapeutic implications. — PubMed · 2014 · Journal Article
- IL-8 enhances the angiogenic potential of human bone marrow mesenchymal stem cells by increasing vascular endothelial growth factor. — PubMed · 2014 · Journal Article
- Modulation of calcium-induced cell death in human neural stem cells by the novel peptidylarginine deiminase-AIF pathway. — PubMed · 2014 · Journal Article
- Characterization of microRNA expression profiles in patients with intervertebral disc degeneration. — PubMed · 2014 · Journal Article
- Exercise immunology meets MiRNAs. — PubMed · 2014 · Journal Article
- Hypoxia as a target for tissue specific gene therapy. — PubMed · 2013 · Journal Article
- Short hairpin RNA against PTEN enhances regenerative growth of corticospinal tract axons after spinal cord injury. — PubMed · 2013 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 0 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 854026 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-05 | the source found 2 · this programme has 1046 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("antisense oligonucleotide" OR "siRNA" OR "microRNA") - Crossref
spinal cord injury antisense oligonucleotide siRNA - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Oligonucleotides, Antisense"[MeSH Terms] OR "RNA, Small Interfering"[MeSH Terms] OR "MicroRNAs"[MeSH Terms] OR "antisense oligonucleotide"[Title/Abstract] OR "siRNA"[Title/Abstract] OR "microRNA"[Title/Abstract])