A subject this map covers
Gene therapy
What belongs here
Introducing, silencing or editing a gene in nervous-system cells after injury.
What does not belong here, however close it looks
Cells engineered in a dish and then transplanted also belong to cell therapy.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 185 records · 1992–2026
- Indexed as work in animals: 221 records · 1994–2026
- Indexed as laboratory work: 18 records · 1997–2021
- The source has not said who or what was studied: 99 records · 1997–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
523 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Evaluation of direct and cell-mediated triple-gene therapy in spinal cord injury in rats. — PubMed · 2017 · Journal Article
- A pilot study of cell-mediated gene therapy for spinal cord injury in mini pigs. — PubMed · 2017 · Journal Article
- Combined chondroitinase and KLF7 expression reduce net retraction of sensory and CST axons from sites of spinal injury. — PubMed · 2017 · Journal Article
- Electrophysiological, Morphological, and Ultrastructural Features of the Injured Spinal Cord Tissue after Transplantation of Human Umbilical Cord Blood Mononuclear Cells Genetically Modified with the VEGF and GDNF Genes. — PubMed · 2017 · Journal Article
- Gene therapy and respiratory neuroplasticity. — PubMed · 2017 · Journal Article
- Neurotrophic Factors Used to Treat Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Canine olfactory ensheathing cells from the olfactory mucosa can be engineered to produce active chondroitinase ABC. — PubMed · 2016 · Journal Article
- Assessment of Glial Scar, Tissue Sparing, Behavioral Recovery and Axonal Regeneration following Acute Transplantation of Genetically Modified Human Umbilical Cord Blood Cells in a Rat Model of Spinal Cord Contusion. — PubMed · 2016 · Journal Article
- Cell Transplantation and Neuroengineering Approach for Spinal Cord Injury Treatment: A Summary of Current Laboratory Findings and Review of Literature. — PubMed · 2016 · Journal Article
- Non Pharmacological Strategies to Promote Spinal Cord Regeneration: A View on Some Individual or Combined Approaches. — PubMed · 2016 · Journal Article
- Pluripotent stem cell applications for regenerative medicine. — PubMed · 2015 · Journal Article
- Applications of the Keap1-Nrf2 system for gene and cell therapy. — PubMed · 2015 · Journal Article
- Neurotrophic factors for spinal cord repair: Which, where, how and when to apply, and for what period of time? — PubMed · 2015 · Journal Article
- [Micro RNA and its role in the pathophysiology of spinal cord injury - a further step towards neuroregenerative medicine]. — PubMed · 2015 · English Abstract
- A Gene and Neural Stem Cell Therapy Platform Based on Neuronal Cell Type-Inducible Gene Overexpression. — PubMed · 2015 · Journal Article
- Spinal cord injury induced neuropathic pain: Molecular targets and therapeutic approaches. — PubMed · 2015 · Journal Article
- Sponge-mediated lentivirus delivery to acute and chronic spinal cord injuries. — PubMed · 2015 · Journal Article
- [Low-dose lipopolysaccharide mediated up-regulation of Nrf2 attenuates inflammatory response in rats with spinal cord injury]. — PubMed · 2015 · English Abstract
- Viral vectors encoding endomorphins and serine histogranin attenuate neuropathic pain symptoms after spinal cord injury in rats. — PubMed · 2015 · Journal Article
- The role of brain-derived neurotrophic factor in bone marrow stromal cell-mediated spinal cord repair. — PubMed · 2015 · Journal Article
- Spinal cord injury and the neuron-intrinsic regeneration-associated gene program. — PubMed · 2014 · Journal Article
- Delayed administration of a bio-engineered zinc-finger VEGF-A gene therapy is neuroprotective and attenuates allodynia following traumatic spinal cord injury. — PubMed · 2014 · Journal Article
- Strengthening the skin with topical delivery of keratinocyte growth factor-1 using a novel DNA plasmid. — PubMed · 2014 · Journal Article
- Adenoviral-mediated glial cell line-derived neurotrophic factor gene transfer has a protective effect on sciatic nerve following constriction-induced spinal cord injury. — PubMed · 2014 · Journal Article
- Enhanced neuroprotection and improved motor function in traumatized rat spinal cords by rAAV2-mediated glial-derived neurotrophic factor combined with early rehabilitation training. — PubMed · 2014 · Journal Article
- Mesenchymal stem cells: potential in treatment of neurodegenerative diseases. — PubMed · 2014 · Journal Article
- Hypoxia as a target for tissue specific gene therapy. — PubMed · 2013 · Journal Article
- Neural stem cell-based treatment for neurodegenerative diseases. — PubMed · 2013 · Journal Article
- Polysaccharide-modified scaffolds for controlled lentivirus delivery in vitro and after spinal cord injury. — PubMed · 2013 · Journal Article
- The therapeutic role of interleukin-10 after spinal cord injury. — PubMed · 2013 · Journal Article
- Usage of plasmid vector carrying vegf and fgf2 genes after spinal cord injury in rats. — PubMed · 2013 · Journal Article
- Inhibition of Nogo expression to promote repair after spinal cord injury. — PubMed · 2012 · Journal Article
- Regenerative medicine for the treatment of spinal cord injury: more than just promises? — PubMed · 2012 · Journal Article
- Dependence of regenerated sensory axons on continuous neurotrophin-3 delivery. — PubMed · 2012 · Journal Article
- Non-viral gene therapy for spinal cord regeneration. — PubMed · 2012 · Journal Article
- Therapeutic gene products delivery by neuron stem cells. — PubMed · 2012 · Journal Article
- Multifunctional, multichannel bridges that deliver neurotrophin encoding lentivirus for regeneration following spinal cord injury. — PubMed · 2012 · Journal Article
- Research yields new insights into mechanisms and treatment of pain. — PubMed · 2012 · News
- Approaches to repairing the damaged spinal cord: overview. — PubMed · 2012 · Journal Article
- Corticospinal tract transduction: a comparison of seven adeno-associated viral vector serotypes and a non-integrating lentiviral vector. — PubMed · 2012 · Comparative Study
- Differential effects of brain-derived neurotrophic factor and neurotrophin-3 on hindlimb function in paraplegic rats. — PubMed · 2012 · Journal Article
- Combination strategies for repair, plasticity, and regeneration using regulation of gene expression during the chronic phase after spinal cord injury. — PubMed · 2011 · Journal Article
- Gene transfer mediated by stem cell grafts to treat CNS injury. — PubMed · 2011 · Journal Article
- Rapid and efficient generation of functional motor neurons from human pluripotent stem cells using gene delivered transcription factor codes. — PubMed · 2011 · Journal Article
- Lentiviral vectors express chondroitinase ABC in cortical projections and promote sprouting of injured corticospinal axons. — PubMed · 2011 · Comparative Study
- Efficient secretion of biologically active Chondroitinase ABC from mammalian cells in the absence of an N-terminal signal peptide. — PubMed · 2011 · Journal Article
- Plasticity after spinal cord injury: relevance to recovery and approaches to facilitate it. — PubMed · 2011 · Journal Article
- Potential therapeutic uses of BDNF in neurological and psychiatric disorders. — PubMed · 2011 · Journal Article
- Branched oligomerization of cell-permeable peptides markedly enhances the transduction efficiency of adenovirus into mesenchymal stem cells. — PubMed · 2010 · Journal Article
- Recent advancements in stem cell and gene therapies for neurological disorders and intractable epilepsy. — PubMed · 2010 · Journal Article
- Transgene-mediated GDNF expression enhances synaptic connectivity and GABA transmission to improve functional outcome after spinal cord contusion. — PubMed · 2010 · Journal Article
- Changes in afferent activity after spinal cord injury. — PubMed · 2010 · Journal Article
- [Current situation and progression in the treatment of spinal cord injury]. — PubMed · 2010 · English Abstract
- Disuse atrophy of human skeletal muscle: cell signaling and potential interventions. — PubMed · 2009 · Journal Article
- The deployment of adenovirus-containing gene activated matrices onto severed axons after central nervous system injury leads to transgene expression in target neuronal cell bodies. — PubMed · 2009 · Journal Article
- Cell therapy for CNS trauma. — PubMed · 2009 · Journal Article
- Strategies for spinal cord repair after injury: a review of the literature and information. — PubMed · 2009 · Journal Article
- Local gene delivery from ECM-coated poly(lactide-co-glycolide) multiple channel bridges after spinal cord injury. — PubMed · 2009 · Journal Article
- Adeno-associated virus-mediated gene delivery approaches for the treatment of CNS disorders. — PubMed · 2008 · Journal Article
- Nonviral approaches for neuronal delivery of nucleic acids. — PubMed · 2008 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 2 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 3660371 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 1 · this programme has 495 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("gene therapy" OR "gene delivery") - Crossref
spinal cord injury gene therapy gene delivery - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Genetic Therapy"[MeSH Terms] OR "gene therapy"[Title/Abstract] OR "gene delivery"[Title/Abstract])