A subject this map covers
Glial scar and its remodelling
What belongs here
The tissue that forms around the lesion, and attempts to change it — soften, remodel or use it.
What does not belong here, however close it looks
Skin or soft-tissue scarring after surgery does not belong here.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 478 records · 1963–2026
- Indexed as work in animals: 879 records · 1969–2026
- Indexed as laboratory work: 59 records · 1992–2026
- The source has not said who or what was studied: 294 records · 1983–2026
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1710 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Dihydrotestosterone reduces neuroinflammation in spinal cord injury through NF-κB and MAPK pathway. — PubMed · 2024 · Journal Article
- Engineered Multifunctional Zinc-Organic Framework-Based Aggregation-Induced Emission Nanozyme for Accelerating Spinal Cord Injury Recovery. — PubMed · 2024 · Journal Article
- ACY1215 Exerts Anti-inflammatory Effects by Inhibition of NF-κB and STAT3 Signaling Pathway to Repair Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Transplantation of Heat-Shock Preconditioned Neural Stem/Progenitor Cells Combined with RGD-Functionalised Hydrogel Promotes Spinal Cord Functional Recovery in a Rat Hemi-Transection Model. — PubMed · 2024 · Journal Article
- 3D collagen porous scaffold carrying PLGA-PTX/SDF-1α recruits and promotes neural stem cell differentiation for spinal cord injury repair. — PubMed · 2023 · Journal Article
- Effects of electroacupuncture on glial scar generation in SCI model rats. — PubMed · 2023 · Journal Article
- Fingolimod (FTY720) Hinders Interferon-γ-Mediated Fibrotic Scar Formation and Facilitates Neurological Recovery After Spinal Cord Injury. — PubMed · 2023 · Journal Article
- P2Y12 receptor mediates apoptosis and demyelination to affect functional recovery in mice with spinal cord injury. — PubMed · 2023 · Journal Article
- Shinbaro2 enhances axonal extension beyond the glial scar for functional recovery in rats with contusive spinal cord injury. — PubMed · 2023 · Journal Article
- Low oral dose of 4-methylumbelliferone reduces glial scar but is insufficient to induce functional recovery after spinal cord injury. — PubMed · 2023 · Journal Article
- Increased astrocytic GLT-1 expression in tripartite synapses is associated with SCI-induced hyperreflexia. — PubMed · 2023 · Journal Article
- Differential expression of genes involved in the chronic response to intracortical microelectrodes. — PubMed · 2023 · Journal Article
- In Situ Cross-Linkable Hyaluronic-Ferulic Acid Conjugate Containing Bucladesine Nanoparticles Promotes Neural Regeneration after Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Analysis of gene expression profiles and experimental validations of a rat chronic cervical cord compression model. — PubMed · 2023 · Journal Article
- Cooperation of long noncoding RNA LOC100909675 and transcriptional regulator CTCF modulates Cdk1 transcript to control astrocyte proliferation. — PubMed · 2023 · Journal Article
- Distribution of 5HT receptors during the regeneration process after spinal cord transection in goldfish. — PubMed · 2023 · Journal Article
- Organization of collagen fibers and tissue hardening: Markers of fibrotic scarring after spinal cord injury in mice revealed by multiphoton-atomic force microscopy imaging. — PubMed · 2023 · Journal Article
- Rolipram-loaded PgP nanoparticle reduces secondary injury and enhances motor function recovery in a rat moderate contusion SCI model. — PubMed · 2023 · Journal Article
- Celsr2-mediated morphological polarization and functional phenotype of reactive astrocytes in neural repair. — PubMed · 2023 · Journal Article
- Evaluation of the Optimal Number of Implanted Mesenchymal Stem Cells for the Treatment of Post-Traumatic Syrinx and Recovery of Motor Activity after Chronic Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Inhibition of Astrocytic Carbohydrate Sulfotransferase 15 Promotes Nerve Repair After Spinal Cord Injury via Mitigation of CSPG Mediated Axonal Inhibition. — PubMed · 2023 · Journal Article
- Microneedle/CD-MOF-mediated transdural controlled release of methylprednisolone sodium succinate after spinal cord injury. — PubMed · 2023 · Journal Article
- The Role of Intraspinal Administration of Self-Assembled Peptide on Locomotion Recovery After Spinal Cord Injury: A Systematic Review and Meta-Analysis Study. — PubMed · 2023 · Meta-Analysis
- Macrophages play a leading role in determining the direction of astrocytic migration in spinal cord injury via ADP-P2Y1R axis. — PubMed · 2023 · Journal Article
- [Neuroprotective effect of tetramethylpyrazine on mice after spinal cord injury]. — PubMed · 2023 · English Abstract
- Open-Spaced Ridged Hydrogel Scaffolds Containing TiO(2)-Self-Assembled Monolayer of Phosphonates Promote Regeneration and Recovery Following Spinal Cord Injury. — PubMed · 2023 · Journal Article
- MiR-155-5p Aggravated Astrocyte Activation and Glial Scarring in a Spinal Cord Injury Model by Inhibiting Ndfip1 Expression and PTEN Nuclear Translocation. — PubMed · 2023 · Journal Article
- Targeting reactive astrocytes by pH-responsive ligand-bonded polymeric nanoparticles in spinal cord injury. — PubMed · 2023 · Journal Article
- Therapeutic administration of mouse mast cell protease 6 improves functional recovery after traumatic spinal cord injury in mice by promoting remyelination and reducing glial scar formation. — PubMed · 2023 · Journal Article
- Adipose-Derived Mesenchymal Stromal Cell Transplantation for Severe Spinal Cord Injury: Functional Improvement Supported by Angiogenesis and Neuroprotection. — PubMed · 2023 · Journal Article
- Effects of Methylprednisolone in the Treatment of Spinal Cord Injuries by Evaluation of microRNA-21: An Experimental Study. — PubMed · 2023 · Journal Article
- Inhibited astrocytic differentiation in neural stem cell-laden 3D bioprinted conductive composite hydrogel scaffolds for repair of spinal cord injury. — PubMed · 2023 · Journal Article
- Lesion Extension and Neuronal Loss after Spinal Cord Injury Using X-Ray Phase-Contrast Tomography in Mice. — PubMed · 2023 · Journal Article
- Astrocytic Cebpd Regulates Pentraxin 3 Expression to Promote Fibrotic Scar Formation After Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Xeomin(®), a Commercial Formulation of Botulinum Neurotoxin Type A, Promotes Regeneration in a Preclinical Model of Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Intranasal Delivery of miR133b in a NEO100-Based Formulation Induces a Healing Response in Spinal Cord-Injured Mice. — PubMed · 2023 · Journal Article
- Mechanism of SET8 Activates the Nrf2-KEAP1-ARE Signaling Pathway to Promote the Recovery of Motor Function after Spinal Cord Injury. — PubMed · 2023 · Journal Article
- USP1/UAF1-Stabilized METTL3 Promotes Reactive Astrogliosis and Improves Functional Recovery after Spinal Cord Injury through m(6)A Modification of YAP1 mRNA. — PubMed · 2023 · Journal Article
- Protective effect of bone morphogenetic protein-7 induced differentiation of bone marrow mesenchymal stem cells in rat with acute spinal cord injury. — PubMed · 2023 · Journal Article
- Canine bone marrow peri-adipocyte cells could therapeutically benefit acute spinal cord injury through migration and secretion of hepatocyte growth factor to inflammatory milieu. — PubMed · 2023 · Journal Article
- Resection of Scar Tissue in Rats With Spinal Cord Injury Can Promote the Expression of βⅢ-tubulin in the Injured Area. — PubMed · 2023 · Journal Article
- Rodent Models of Spinal Cord Injury: From Pathology to Application. — PubMed · 2023 · Journal Article
- Spatiotemporal Dynamics of the Molecular Expression Pattern and Intercellular Interactions in the Glial Scar Response to Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Baicalein-functionalized collagen scaffolds direct neuronal differentiation toward enhancing spinal cord injury repair. — PubMed · 2023 · Journal Article
- Tocilizumab promotes repair of spinal cord injury by facilitating the restoration of tight junctions between vascular endothelial cells. — PubMed · 2023 · Journal Article
- 3,4-Dimethoxychalcone, a caloric restriction mimetic, enhances TFEB-mediated autophagy and alleviates pyroptosis and necroptosis after spinal cord injury. — PubMed · 2023 · Journal Article
- 3D Gelatin Microsphere Scaffolds Promote Functional Recovery after Spinal Cord Hemisection in Rats. — PubMed · 2023 · Journal Article
- Equilibrative Nucleoside Transporter 1 is a Target to Modulate Neuroinflammation and Improve Functional Recovery in Mice with Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Recognition of necrotic regions in MRI images of chronic spinal cord injury based on superpixel. — PubMed · 2023 · Journal Article
- Forced Remyelination Promotes Axon Regeneration in a Rat Model of Spinal Cord Injury. — PubMed · 2022 · Journal Article
- 5-Fluorouracil reduces the fibrotic scar via inhibiting matrix metalloproteinase 9 and stabilizing microtubules after spinal cord injury. — PubMed · 2022 · Journal Article
- Apigenin inhibits fibrous scar formation after acute spinal cord injury through TGFβ/SMADs signaling pathway. — PubMed · 2022 · Journal Article
- A Localized Materials-Based Strategy to Non-Virally Deliver Chondroitinase ABC mRNA Improves Hindlimb Function in a Rat Spinal Cord Injury Model. — PubMed · 2022 · Journal Article
- Forsythoside B attenuates neuro-inflammation and neuronal apoptosis by inhibition of NF-κB and p38-MAPK signaling pathways through activating Nrf2 post spinal cord injury. — PubMed · 2022 · Journal Article
- Polyphenolic grape stalk and coffee extracts attenuate spinal cord injury-induced neuropathic pain development in ICR-CD1 female mice. — PubMed · 2022 · Journal Article
- 7,8-Dihydroxyflavone accelerates recovery of Brown-Sequard syndrome in adult female rats with spinal cord lateral hemisection. — PubMed · 2022 · Journal Article
- Identification of hub genes in the subacute spinal cord injury in rats. — PubMed · 2022 · Journal Article
- Heterogeneity analysis of astrocytes following spinal cord injury at single-cell resolution. — PubMed · 2022 · Journal Article
- Magnesium Oxide/Poly(l-lactide-co-ε-caprolactone) Scaffolds Loaded with Neural Morphogens Promote Spinal Cord Repair through Targeting the Calcium Influx and Neuronal Differentiation of Neural Stem Cells. — PubMed · 2022 · Journal Article
- LncRNA/miRNA/mRNA ceRNA network analysis in spinal cord injury rat with physical exercise therapy. — PubMed · 2022 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 4 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851162 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 7 · this programme has 1725 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("glial scar" OR "astrogliosis" OR "fibrotic scar") - Crossref
spinal cord injury glial scar astrogliosis - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Gliosis"[MeSH Terms] OR "Cicatrix"[MeSH Terms] OR "glial scar"[Title/Abstract] OR "astrogliosis"[Title/Abstract] OR "fibrotic scar"[Title/Abstract])