A subject this map covers
Glial scar and its remodelling
What belongs here
The tissue that forms around the lesion, and attempts to change it — soften, remodel or use it.
What does not belong here, however close it looks
Skin or soft-tissue scarring after surgery does not belong here.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 478 records · 1963–2026
- Indexed as work in animals: 879 records · 1969–2026
- Indexed as laboratory work: 59 records · 1992–2026
- The source has not said who or what was studied: 294 records · 1983–2026
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1710 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Chronic spinal cord injury repair by NT3-chitosan only occurs after clearance of the lesion scar. — PubMed · 2022 · Journal Article
- Efficacy of hydrogels for repair of traumatic spinal cord injuries: A systematic review and meta-analysis. — PubMed · 2022 · Journal Article
- Synaptic Cell Adhesion Molecule 3 (SynCAM3) Deletion Promotes Recovery from Spinal Cord Injury by Limiting Glial Scar Formation. — PubMed · 2022 · Journal Article
- Highly bioactive iridium metal-complex alleviates spinal cord injury via ROS scavenging and inflammation reduction. — PubMed · 2022 · Journal Article
- SU16f inhibits fibrotic scar formation and facilitates axon regeneration and locomotor function recovery after spinal cord injury by blocking the PDGFRβ pathway. — PubMed · 2022 · Journal Article
- Photobiomodulation Attenuates Neurotoxic Polarization of Macrophages by Inhibiting the Notch1-HIF-1α/NF-κB Signalling Pathway in Mice With Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Characterization of a Novel Aspect of Tissue Scarring Following Experimental Spinal Cord Injury and the Implantation of Bioengineered Type-I Collagen Scaffolds in the Adult Rat: Involvement of Perineurial-like Cells? — PubMed · 2022 · Journal Article
- Ski regulates proliferation and migration of reactive astrocytes induced by lipopolysaccharide (LPS) through PI3K/Akt pathway. — PubMed · 2022 · Journal Article
- Rewired glycosylation activity promotes scarless regeneration and functional recovery in spiny mice after complete spinal cord transection. — PubMed · 2022 · Journal Article
- Expression Pattern of Ngb in Astrocytes after Spinal Cord Injury and the Clinical Significance. — PubMed · 2022 · Journal Article
- Improved functional recovery of rat transected spinal cord by peptide-grafted PNIPAM based hydrogel. — PubMed · 2022 · Journal Article
- The effect of low-level laser therapy on pathophysiology and locomotor recovery after traumatic spinal cord injuries: a systematic review and meta-analysis. — PubMed · 2022 · Journal Article
- Optimized, visible light-induced crosslinkable hybrid gelatin/hyaluronic acid scaffold promotes complete spinal cord injury repair. — PubMed · 2022 · Journal Article
- Activation of glucagon-like peptide-1 receptor in microglia attenuates neuroinflammation-induced glial scarring via rescuing Arf and Rho GAP adapter protein 3 expressions after nerve injury. — PubMed · 2022 · Journal Article
- Application of developmental principles for spinal cord repair after injury. — PubMed · 2022 · Journal Article
- Long-Term Effects of Neural Precursor Cell Transplantation on Secondary Injury Processes and Functional Recovery after Severe Cervical Contusion-Compression Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Expression of matrix metalloproteinases during axonal regeneration in the goldfish spinal cord. — PubMed · 2021 · Journal Article
- Inhibition of Autophagy Flux Promotes Secretion of Chondroitin Sulfate Proteoglycans in Primary Rat Astrocytes. — PubMed · 2021 · Journal Article
- Chondroitin 6-sulfate-binding peptides improve recovery in spinal cord-injured mice. — PubMed · 2021 · Journal Article
- Effect of L-carnitine and atorvastatin on a rat model of ischemia-reperfusion injury of spinal cord. — PubMed · 2021 · Journal Article
- Lipocalin 2 as a Putative Modulator of Local Inflammatory Processes in the Spinal Cord and Component of Organ Cross talk After Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Resveratrol Can Attenuate Astrocyte Activation to Treat Spinal Cord Injury by Inhibiting Inflammatory Responses. — PubMed · 2021 · Journal Article
- Deletion or Inhibition of Astrocytic Transglutaminase 2 Promotes Functional Recovery after Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Implantation of Engineered Axon Tracts to Bridge Spinal Cord Injury Beyond the Glial Scar in Rats. — PubMed · 2021 · Journal Article
- Transplantation of a vascularized pedicle of hemisected spinal cord to establish spinal cord continuity after removal of a segment of the thoracic spinal cord: A proof-of-principle study in dogs. — PubMed · 2021 · Journal Article
- Neutrophil, Extracellular Matrix Components, and Their Interlinked Action in Promoting Secondary Pathogenesis After Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Gsx1 promotes locomotor functional recovery after spinal cord injury. — PubMed · 2021 · Journal Article
- Single-cell analysis of the cellular heterogeneity and interactions in the injured mouse spinal cord. — PubMed · 2021 · Journal Article
- Scar tissue removal-activated endogenous neural stem cells aid Taxol-modified collagen scaffolds in repairing chronic long-distance transected spinal cord injury. — PubMed · 2021 · Journal Article
- Targeting senescent cells improves functional recovery after spinal cord injury. — PubMed · 2021 · Journal Article
- Comparison of the effects of two therapeutic strategies based on olfactory ensheathing cell transplantation and repetitive magnetic stimulation after spinal cord injury in female mice. — PubMed · 2021 · Comparative Study
- Deubiquitinase USP18 regulates reactive astrogliosis by stabilizing SOX9. — PubMed · 2021 · Journal Article
- Chondroitinase ABC/galectin-3 fusion proteins with hyaluronan-based hydrogels stabilize enzyme and provide targeted enzyme activity for neural applications. — PubMed · 2021 · Journal Article
- SiRNA in MSC-derived exosomes silences CTGF gene for locomotor recovery in spinal cord injury rats. — PubMed · 2021 · Journal Article
- EphB2 knockdown decreases the formation of astroglial-fibrotic scars to promote nerve regeneration after spinal cord injury in rats. — PubMed · 2021 · Journal Article
- Sonic Hedgehog modulates the inflammatory response and improves functional recovery after spinal cord injury in a thoracic contusion-compression model. — PubMed · 2021 · Journal Article
- In vivo reprogramming of NG2 glia enables adult neurogenesis and functional recovery following spinal cord injury. — PubMed · 2021 · Journal Article
- Collagen/heparin sulfate scaffold combined with mesenchymal stem cells treatment for canines with spinal cord injury: A pilot feasibility study. — PubMed · 2021 · Journal Article
- [Expression of Semaphorin 3A after spinal cord injury]. — PubMed · 2021 · Journal Article
- CXCL12 promotes spinal nerve regeneration and functional recovery after spinal cord injury. — PubMed · 2021 · Journal Article
- AAV2-mediated and hypoxia response element-directed expression of bFGF in neural stem cells showed therapeutic effects on spinal cord injury in rats. — PubMed · 2021 · Journal Article
- hiPSC-derived NSCs effectively promote the functional recovery of acute spinal cord injury in mice. — PubMed · 2021 · Journal Article
- A switch in pdgfrb(+) cell-derived ECM composition prevents inhibitory scarring and promotes axon regeneration in the zebrafish spinal cord. — PubMed · 2021 · Journal Article
- Different Functions of Recombinantly Expressed Domains of Tenascin-C in Glial Scar Formation. — PubMed · 2021 · Journal Article
- Cellular response to spinal cord injury in regenerative and non-regenerative stages in Xenopus laevis. — PubMed · 2021 · Journal Article
- Exosomes derived from GIT1-overexpressing bone marrow mesenchymal stem cells promote traumatic spinal cord injury recovery in a rat model. — PubMed · 2021 · Journal Article
- Local delivery of RhoA siRNA by PgP nanocarrier reduces inflammatory response and improves neuronal cell survival in a rat TBI model. — PubMed · 2021 · Journal Article
- Nanoparticle-Based Estrogen Delivery to Spinal Cord Injury Site Reduces Local Parenchymal Destruction and Improves Functional Recovery. — PubMed · 2021 · Journal Article
- Neuregulin-1 converts reactive astrocytes toward oligodendrocyte lineage cells via upregulating the PI3K-AKT-mTOR pathway to repair spinal cord injury. — PubMed · 2021 · Journal Article
- Microglial inflammation after chronic spinal cord injury is enhanced by reactive astrocytes via the fibronectin/β1 integrin pathway. — PubMed · 2021 · Journal Article
- Imaging of Neurotrauma in Acute and Chronic Settings. — PubMed · 2021 · Journal Article
- Resolvin D3 Promotes Inflammatory Resolution, Neuroprotection, and Functional Recovery After Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Combination of In Situ Lcn2 pRNA-RNAi Nanotherapeutics and iNSC Transplantation Ameliorates Experimental SCI in Mice. — PubMed · 2020 · Journal Article
- The relationship between macrophage polarization and glial scar formation in mouse model of spinal cord injury. — PubMed · 2020 · Journal Article
- PTEN-silencing combined with ChABC-overexpression in adipose-derived stem cells promotes functional recovery of spinal cord injury in rats. — PubMed · 2020 · Journal Article
- Astrocytic reprogramming combined with rehabilitation strategy improves recovery from spinal cord injury. — PubMed · 2020 · Journal Article
- Microglia-organized scar-free spinal cord repair in neonatal mice. — PubMed · 2020 · Journal Article
- [Effect and mechanism of glycyrrhizin on glial scar formation after spinal cord injury in rats]. — PubMed · 2020 · Journal Article
- The Regenerative Effect of Trans-spinal Magnetic Stimulation After Spinal Cord Injury: Mechanisms and Pathways Underlying the Effect. — PubMed · 2020 · Journal Article
- Duraplasty of PHBV/PLA/Col membranes promotes axonal regeneration by inhibiting NLRP3 complex and M1 macrophage polarization in rats with spinal cord injury. — PubMed · 2020 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 4 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851162 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 7 · this programme has 1725 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("glial scar" OR "astrogliosis" OR "fibrotic scar") - Crossref
spinal cord injury glial scar astrogliosis - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Gliosis"[MeSH Terms] OR "Cicatrix"[MeSH Terms] OR "glial scar"[Title/Abstract] OR "astrogliosis"[Title/Abstract] OR "fibrotic scar"[Title/Abstract])