A subject this map covers
Glial scar and its remodelling
What belongs here
The tissue that forms around the lesion, and attempts to change it — soften, remodel or use it.
What does not belong here, however close it looks
Skin or soft-tissue scarring after surgery does not belong here.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 478 records · 1963–2026
- Indexed as work in animals: 879 records · 1969–2026
- Indexed as laboratory work: 59 records · 1992–2026
- The source has not said who or what was studied: 294 records · 1983–2026
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1710 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Overexpression of the transcription factors OCT4 and KLF4 improves motor function after spinal cord injury. — PubMed · 2020 · Journal Article
- Multichannel Bioactive Silk Nanofiber Conduits Direct and Enhance Axonal Regeneration after Spinal Cord Injury. — PubMed · 2020 · Journal Article
- FTY720 Attenuates Neuropathic Pain after Spinal Cord Injury by Decreasing Systemic and Local Inflammation in a Rat Spinal Cord Compression Model. — PubMed · 2020 · Journal Article
- Revealing the Therapeutic Potential of Botulinum Neurotoxin Type A in Counteracting Paralysis and Neuropathic Pain in Spinally Injured Mice. — PubMed · 2020 · Journal Article
- Transplantation of Skin Precursor-Derived Schwann Cells Yields Better Locomotor Outcomes and Reduces Bladder Pathology in Rats with Chronic Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Depletion of microglia exacerbates injury and impairs function recovery after spinal cord injury in mice. — PubMed · 2020 · Journal Article
- An elastic gel consisting of natural polyphenol and pluronic for simultaneous dura sealing and treatment of spinal cord injury. — PubMed · 2020 · Journal Article
- A novel poly-ε-lysine based implant, Proliferate®, for promotion of CNS repair following spinal cord injury. — PubMed · 2020 · Journal Article
- A Western diet impairs CNS energy homeostasis and recovery after spinal cord injury: Link to astrocyte metabolism. — PubMed · 2020 · Journal Article
- Excess administration of miR-340-5p ameliorates spinal cord injury-induced neuroinflammation and apoptosis by modulating the P38-MAPK signaling pathway. — PubMed · 2020 · Journal Article
- The effect of a nanofiber-hydrogel composite on neural tissue repair and regeneration in the contused spinal cord. — PubMed · 2020 · Journal Article
- Thermosensitive heparin-poloxamer hydrogel encapsulated bFGF and NGF to treat spinal cord injury. — PubMed · 2020 · Journal Article
- Recovery of motor function after traumatic spinal cord injury by using plasma-synthesized polypyrrole/iodine application in combination with a mixed rehabilitation scheme. — PubMed · 2020 · Journal Article
- Zeb2 Is a Regulator of Astrogliosis and Functional Recovery after CNS Injury. — PubMed · 2020 · Journal Article
- Nogo receptor decoy promotes recovery and corticospinal growth in non-human primate spinal cord injury. — PubMed · 2020 · Journal Article
- Anti-IL-20 antibody improved motor function and reduced glial scar formation after traumatic spinal cord injury in rats. — PubMed · 2020 · Journal Article
- Polydatin promotes the neuronal differentiation of bone marrow mesenchymal stem cells in vitro and in vivo: Involvement of Nrf2 signalling pathway. — PubMed · 2020 · Journal Article
- The combined effect of granulocyte-colony stimulating factor (G-CSF) treatment and exercise in rats with spinal cord injury. — PubMed · 2020 · Journal Article
- Anisotropic Alginate Hydrogels Promote Axonal Growth across Chronic Spinal Cord Transections after Scar Removal. — PubMed · 2020 · Journal Article
- Photobiomodulation by diffusing optical fiber on spinal cord: A feasibility study in piglet model. — PubMed · 2020 · Journal Article
- Polarization of Reactive Astrocytes in Response to Spinal Cord Injury is Enhanced by M2 Macrophage-Mediated Activation of Wnt/β-Catenin Pathway. — PubMed · 2020 · Journal Article
- Profilin 1 delivery tunes cytoskeletal dynamics toward CNS axon regeneration. — PubMed · 2020 · Journal Article
- Astrocytic YAP Promotes the Formation of Glia Scars and Neural Regeneration after Spinal Cord Injury. — PubMed · 2020 · Journal Article
- ChABC-loaded PLGA nanoparticles: A comprehensive study on biocompatibility, functional recovery, and axonal regeneration in animal model of spinal cord injury. — PubMed · 2020 · Journal Article
- Acute upregulation of bone morphogenetic protein-4 regulates endogenous cell response and promotes cell death in spinal cord injury. — PubMed · 2020 · Journal Article
- Astroglial TLR9 antagonism promotes chemotaxis and alternative activation of macrophages via modulation of astrocyte-derived signals: implications for spinal cord injury. — PubMed · 2020 · Journal Article
- Melatonin exerts neuroprotective effects by attenuating astro- and microgliosis and suppressing inflammatory response following spinal cord injury. — PubMed · 2020 · Journal Article
- Scar Tissue-Targeting Polymer Micelle for Spinal Cord Injury Treatment. — PubMed · 2020 · Journal Article
- ASK1 phosphorylation regulates astrocytic reactive gliosis in vitro and in vivo. — PubMed · 2020 · Journal Article
- Enhanced Neural Regeneration with a Concomitant Treatment of Framework Nucleic Acid and Stem Cells in Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Photobiomodulation Therapy Inhibit the Activation and Secretory of Astrocytes by Altering Macrophage Polarization. — PubMed · 2020 · Journal Article
- Spatiotemporal distribution of chondroitin sulfate proteoglycans after optic nerve injury in rodents. — PubMed · 2020 · Journal Article
- In vivo conversion of rat astrocytes into neuronal cells through neural stem cells in injured spinal cord with a single zinc-finger transcription factor. — PubMed · 2019 · Journal Article
- Effect of curcumin on the inflammatory reaction and functional recovery after spinal cord injury in a hyperglycemic rat model. — PubMed · 2019 · Journal Article
- Blocking Notch signal pathway suppresses the activation of neurotoxic A1 astrocytes after spinal cord injury. — PubMed · 2019 · Journal Article
- Hyperbaric Oxygen Improves Functional Recovery of the Injured Spinal Cord by Inhibiting Inflammation and Glial Scar Formation. — PubMed · 2019 · Journal Article
- LINGO-1 deficiency promotes nerve regeneration through reduction of cell apoptosis, inflammation, and glial scar after spinal cord injury in mice. — PubMed · 2019 · Journal Article
- Prospects of siRNA cocktails as tools for modifying multiple gene targets in the injured spinal cord. — PubMed · 2019 · Journal Article
- Targeting miR-106-3p facilitates functional recovery via inactivating inflammatory microglia and interfering glial scar component deposition after neural injury. — PubMed · 2019 · Journal Article
- Nano-formulated curcumin (Lipodisq™) modulates the local inflammatory response, reduces glial scar and preserves the white matter after spinal cord injury in rats. — PubMed · 2019 · Journal Article
- Comparison of the clinical and radiographic appearance of the cervical vertebrae with histological and anatomical findings in an eight-month old warmblood stallion suffering from cervical vertebral stenotic myelopathy (CVSM). — PubMed · 2019 · Case Reports
- Conditional ablation of reactive astrocytes to dissect their roles in spinal cord injury and repair. — PubMed · 2019 · Journal Article
- Toll-like receptor 9 antagonism modulates astrocyte function and preserves proximal axons following spinal cord injury. — PubMed · 2019 · Journal Article
- Upregulation of proteoglycans in the perilesion perimeter in ventral horns after spinal cord injury. — PubMed · 2019 · Journal Article
- Harpagide inhibits neuronal apoptosis and promotes axonal regeneration after spinal cord injury in rats by activating the Wnt/β-catenin signaling pathway. — PubMed · 2019 · Journal Article
- Protease-activated receptor-2 regulates glial scar formation via JNK signaling. — PubMed · 2019 · Journal Article
- Can Minocycline Become the Magic Pill of Spinal Cord Protection? — PubMed · 2019 · Editorial
- Hyperglycemia aggravates spinal cord injury through endoplasmic reticulum stress mediated neuronal apoptosis, gliosis and activation. — PubMed · 2019 · Journal Article
- TGN-020 alleviates edema and inhibits astrocyte activation and glial scar formation after spinal cord compression injury in rats. — PubMed · 2019 · Journal Article
- Activating Adiponectin Signaling with Exogenous AdipoRon Reduces Myelin Lipid Accumulation and Suppresses Macrophage Recruitment after Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Knockdown of Fidgetin Improves Regeneration of Injured Axons by a Microtubule-Based Mechanism. — PubMed · 2019 · Journal Article
- Local delivery of stabilized chondroitinase ABC degrades chondroitin sulfate proteoglycans in stroke-injured rat brains. — PubMed · 2019 · Journal Article
- Mouse mast cell protease 4 suppresses scar formation after traumatic spinal cord injury. — PubMed · 2019 · Journal Article
- Study on the pathological and biomedical characteristics of spinal cord injury by confocal Raman microspectral imaging. — PubMed · 2019 · Journal Article
- Aligned hydrogel tubes guide regeneration following spinal cord injury. — PubMed · 2019 · Journal Article
- Biohybrids for spinal cord injury repair. — PubMed · 2019 · Journal Article
- Devising micro/nano-architectures in multi-channel nerve conduits towards a pro-regenerative matrix for the repair of spinal cord injury. — PubMed · 2019 · Journal Article
- Ferroptosis inhibitor SRS 16-86 attenuates ferroptosis and promotes functional recovery in contusion spinal cord injury. — PubMed · 2019 · Journal Article
- Microvascular endothelial cells engulf myelin debris and promote macrophage recruitment and fibrosis after neural injury. — PubMed · 2019 · Journal Article
- Effects of Different Doses of Mesenchymal Stem Cells on Functional Recovery After Compressive Spinal-Cord Injury in Mice. — PubMed · 2019 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 4 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851162 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 7 · this programme has 1725 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("glial scar" OR "astrogliosis" OR "fibrotic scar") - Crossref
spinal cord injury glial scar astrogliosis - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Gliosis"[MeSH Terms] OR "Cicatrix"[MeSH Terms] OR "glial scar"[Title/Abstract] OR "astrogliosis"[Title/Abstract] OR "fibrotic scar"[Title/Abstract])