A subject this map covers
Glial scar and its remodelling
What belongs here
The tissue that forms around the lesion, and attempts to change it — soften, remodel or use it.
What does not belong here, however close it looks
Skin or soft-tissue scarring after surgery does not belong here.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 478 records · 1963–2026
- Indexed as work in animals: 879 records · 1969–2026
- Indexed as laboratory work: 59 records · 1992–2026
- The source has not said who or what was studied: 294 records · 1983–2026
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1710 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Local application of MDL28170-loaded PCL film improves functional recovery by preserving survival of motor neurons after traumatic spinal cord injury. — PubMed · 2019 · Journal Article
- Polysialic-Acid-Based Micelles Promote Neural Regeneration in Spinal Cord Injury Therapy. — PubMed · 2019 · Journal Article
- Exosomes Derived from Bone Mesenchymal Stem Cells Repair Traumatic Spinal Cord Injury by Suppressing the Activation of A1 Neurotoxic Reactive Astrocytes. — PubMed · 2019 · Journal Article
- Induced NB-3 Limits Regenerative Potential of Serotonergic Axons after Complete Spinal Transection. — PubMed · 2019 · Journal Article
- Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury. — PubMed · 2019 · Journal Article
- An anti-inflammatory peptide and brain-derived neurotrophic factor-modified hyaluronan-methylcellulose hydrogel promotes nerve regeneration in rats with spinal cord injury. — PubMed · 2019 · Journal Article
- Epidural oscillating field stimulation as an effective therapeutic approach in combination therapy for spinal cord injury. — PubMed · 2019 · Journal Article
- Histone H1 improves regeneration after mouse spinal cord injury and changes shape and gene expression of cultured astrocytes. — PubMed · 2019 · Journal Article
- Motor Recovery after Chronic Spinal Cord Transection in Rats: A Proof-of-Concept Study Evaluating a Combined Strategy. — PubMed · 2019 · Journal Article
- Longitudinal Magnetic Resonance Imaging Analysis and Histological Characterization after Spinal Cord Injury in Two Mouse Strains with Different Functional Recovery: Gliosis as a Key Factor. — PubMed · 2018 · Journal Article
- Blood Glutamate Scavenger as a Novel Neuroprotective Treatment in Spinal Cord Injury. — PubMed · 2018 · Journal Article
- PHBV/PLA/Col-Based Nanofibrous Scaffolds Promote Recovery of Locomotor Function by Decreasing Reactive Astrogliosis in a Hemisection Spinal Cord Injury Rat Model. — PubMed · 2018 · Journal Article
- Decreased expression of LATS1 correlates with astrogliosis after spinal cord injury. — PubMed · 2018 · Journal Article
- Injury type-dependent differentiation of NG2 glia into heterogeneous astrocytes. — PubMed · 2018 · Journal Article
- MicroRNA-21a-5p promotes fibrosis in spinal fibroblasts after mechanical trauma. — PubMed · 2018 · Journal Article
- Required growth facilitators propel axon regeneration across complete spinal cord injury. — PubMed · 2018 · Journal Article
- Neuroprotection and immunomodulation following intraspinal axotomy of motoneurons by treatment with adult mesenchymal stem cells. — PubMed · 2018 · Journal Article
- Novel multi-drug delivery hydrogel using scar-homing liposomes improves spinal cord injury repair. — PubMed · 2018 · Journal Article
- Combined effects of rat Schwann cells and 17β-estradiol in a spinal cord injury model. — PubMed · 2018 · Journal Article
- Comparison of subacute and chronic scar tissues after complete spinal cord transection. — PubMed · 2018 · Comparative Study
- Fibronectin EDA forms the chronic fibrotic scar after contusive spinal cord injury. — PubMed · 2018 · Journal Article
- Safety and Efficacy of Rose Bengal Derivatives for Glial Scar Ablation in Chronic Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Systemic administration of epothilone D improves functional recovery of walking after rat spinal cord contusion injury. — PubMed · 2018 · Journal Article
- Systemic epothilone D improves hindlimb function after spinal cord contusion injury in rats. — PubMed · 2018 · Journal Article
- Intraspinal Grafting of Serotonergic Neurons Modifies Expression of Genes Important for Functional Recovery in Paraplegic Rats. — PubMed · 2018 · Journal Article
- microRNA-21 regulates astrocytic reaction post-acute phase of spinal cord injury through modulating TGF-β signaling. — PubMed · 2018 · Journal Article
- Diffusion Tensor Imaging of Scarring, Necrosis, and Cavitation Based on Histopathological Findings in Dogs with Chronic Spinal Cord Injury: Evaluation of Multiple Diffusion Parameters and Their Correlations with Histopathological Findings. — PubMed · 2018 · Journal Article
- Knockdown of Ski decreased the reactive astrocytes proliferation in vitro induced by oxygen-glucose deprivation/reoxygenation. — PubMed · 2018 · Journal Article
- Directing Induced Pluripotent Stem Cell Derived Neural Stem Cell Fate with a Three-Dimensional Biomimetic Hydrogel for Spinal Cord Injury Repair. — PubMed · 2018 · Journal Article
- Bone marrow mesenchymal stem cells (BMSCs) improved functional recovery of spinal cord injury partly by promoting axonal regeneration. — PubMed · 2018 · Journal Article
- Plumbagin ameliorates memory dysfunction in streptozotocin induced Alzheimer's disease via activation of Nrf2/ARE pathway and inhibition of β-secretase. — PubMed · 2018 · Journal Article
- Taxol-modified collagen scaffold implantation promotes functional recovery after long-distance spinal cord complete transection in canines. — PubMed · 2018 · Journal Article
- The human natural killer-1 (HNK-1) glycan mimetic ursolic acid promotes functional recovery after spinal cord injury in mouse. — PubMed · 2018 · Journal Article
- S1P/S1PR3 signaling mediated proliferation of pericytes via Ras/pERK pathway and CAY10444 had beneficial effects on spinal cord injury. — PubMed · 2018 · Journal Article
- Leucine Zipper-Bearing Kinase Is a Critical Regulator of Astrocyte Reactivity in the Adult Mammalian CNS. — PubMed · 2018 · Journal Article
- Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Increased vascularization promotes functional recovery in the transected spinal cord rats by implanted vascular endothelial growth factor-targeting collagen scaffold. — PubMed · 2018 · Journal Article
- Non-functionalized soft alginate hydrogel promotes locomotor recovery after spinal cord injury in a rat hemimyelonectomy model. — PubMed · 2018 · Journal Article
- Temporal Profile and Severity Correlation of a Panel of Rat Spinal Cord Injury Protein Biomarkers. — PubMed · 2018 · Journal Article
- Therapeutic time window for the effects of erythropoietin on astrogliosis and neurite outgrowth in an in vitro model of spinal cord injury. — PubMed · 2018 · Journal Article
- Transplantation of a Peripheral Nerve with Neural Stem Cells Plus Lithium Chloride Injection Promote the Recovery of Rat Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Transient activation of Wnt/β-catenin signaling reporter in fibrotic scar formation after compression spinal cord injury in adult mice. — PubMed · 2018 · Journal Article
- Proliferating NG2-Cell-Dependent Angiogenesis and Scar Formation Alter Axon Growth and Functional Recovery After Spinal Cord Injury in Mice. — PubMed · 2018 · Journal Article
- STAT3: Down the R(h)oAd. — PubMed · 2018 · Journal Article
- MicroRNA-21-5p mediates TGF-β-regulated fibrogenic activation of spinal fibroblasts and the formation of fibrotic scars after spinal cord injury. — PubMed · 2018 · Journal Article
- FM19G11 and Ependymal Progenitor/Stem Cell Combinatory Treatment Enhances Neuronal Preservation and Oligodendrogenesis after Severe Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Anti-inflammatory compound curcumin and mesenchymal stem cells in the treatment of spinal cord injury in rats. — PubMed · 2018 · Journal Article
- A Small Organic Compound Mimicking the L1 Cell Adhesion Molecule Promotes Functional Recovery after Spinal Cord Injury in Zebrafish. — PubMed · 2018 · Journal Article
- Continuous tamoxifen delivery improves locomotor recovery 6h after spinal cord injury by neuronal and glial mechanisms in male rats. — PubMed · 2018 · Journal Article
- Effect of CLIP3 Upregulation on Astrocyte Proliferation and Subsequent Glial Scar Formation in the Rat Spinal Cord via STAT3 Pathway After Injury. — PubMed · 2018 · Journal Article
- Label-Free Spectral Imaging Unveils Biochemical Mechanisms of Low-Level Laser Therapy on Spinal Cord Injury. — PubMed · 2018 · Journal Article
- Lentivirus-mediated silencing of the CTGF gene suppresses the formation of glial scar tissue in a rat model of spinal cord injury. — PubMed · 2018 · Journal Article
- Phenelzine, a small organic compound mimicking the functions of cell adhesion molecule L1, promotes functional recovery after mouse spinal cord injury. — PubMed · 2018 · Journal Article
- Resveratrol Activated Sonic Hedgehog Signaling to Enhance Viability of NIH3T3 Cells in Vitro via Regulation of Sirt1. — PubMed · 2018 · Journal Article
- Surgical techniques influence local environment of injured spinal cord and cause various grafted cell survival and integration. — PubMed · 2018 · Journal Article
- Transplantation of canine olfactory ensheathing cells producing chondroitinase ABC promotes chondroitin sulphate proteoglycan digestion and axonal sprouting following spinal cord injury. — PubMed · 2017 · Journal Article
- Combining Constitutively Active Rheb Expression and Chondroitinase Promotes Functional Axonal Regeneration after Cervical Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Intravenous immune-modifying nanoparticles as a therapy for spinal cord injury in mice. — PubMed · 2017 · Journal Article
- Spatiotemporal expression of FOXA1 correlates with reactive gliosis after spinal cord injury. — PubMed · 2017 · Journal Article
- Different Mixed Astrocyte Populations Derived from Embryonic Stem Cells Have Variable Neuronal Growth Support Capacities. — PubMed · 2017 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 4 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851162 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 7 · this programme has 1725 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("glial scar" OR "astrogliosis" OR "fibrotic scar") - Crossref
spinal cord injury glial scar astrogliosis - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Gliosis"[MeSH Terms] OR "Cicatrix"[MeSH Terms] OR "glial scar"[Title/Abstract] OR "astrogliosis"[Title/Abstract] OR "fibrotic scar"[Title/Abstract])