A subject this map covers
Glial scar and its remodelling
What belongs here
The tissue that forms around the lesion, and attempts to change it — soften, remodel or use it.
What does not belong here, however close it looks
Skin or soft-tissue scarring after surgery does not belong here.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 478 records · 1963–2026
- Indexed as work in animals: 879 records · 1969–2026
- Indexed as laboratory work: 59 records · 1992–2026
- The source has not said who or what was studied: 294 records · 1983–2026
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1710 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- A green tea polyphenol epigallocatechin-3-gallate enhances neuroregeneration after spinal cord injury by altering levels of inflammatory cytokines. — PubMed · 2017 · Journal Article
- Effective improvement of the neuroprotective activity after spinal cord injury by synergistic effect of glucocorticoid with biodegradable amphipathic nanomicelles. — PubMed · 2017 · Journal Article
- Low-dose fractionated irradiation promotes axonal regeneration beyond reactive gliosis and facilitates locomotor function recovery after spinal cord injury in beagle dogs. — PubMed · 2017 · Journal Article
- PPP1CC is associated with astrocyte and microglia proliferation after traumatic spinal cord injury in rats. — PubMed · 2017 · Journal Article
- Chondroitin sulfates do not impede axonal regeneration in goldfish spinal cord. — PubMed · 2017 · Journal Article
- Targeting Enolase in Reducing Secondary Damage in Acute Spinal Cord Injury in Rats. — PubMed · 2017 · Journal Article
- Thermosensitive heparin-poloxamer hydrogels enhance the effects of GDNF on neuronal circuit remodeling and neuroprotection after spinal cord injury. — PubMed · 2017 · Journal Article
- Systemic Neutrophil Depletion Modulates the Migration and Fate of Transplanted Human Neural Stem Cells to Rescue Functional Repair. — PubMed · 2017 · Journal Article
- Cellular reactions and compensatory tissue re-organization during spontaneous recovery after spinal cord injury in neonatal mice. — PubMed · 2017 · Journal Article
- Physical chitosan microhydrogels as scaffolds for spinal cord injury restoration and axon regeneration. — PubMed · 2017 · Journal Article
- Trimebutine, a small molecule mimetic agonist of adhesion molecule L1, contributes to functional recovery after spinal cord injury in mice. — PubMed · 2017 · Journal Article
- Neural stem cell mediated recovery is enhanced by Chondroitinase ABC pretreatment in chronic cervical spinal cord injury. — PubMed · 2017 · Journal Article
- Spinal Cord Injury Impairs Neurogenesis and Induces Glial Reactivity in the Hippocampus. — PubMed · 2017 · Journal Article
- Interaction of reactive astrocytes with type I collagen induces astrocytic scar formation through the integrin-N-cadherin pathway after spinal cord injury. — PubMed · 2017 · Journal Article
- Local delivery of chondroitinase ABC with or without stromal cell-derived factor 1α promotes functional repair in the injured rat spinal cord. — PubMed · 2017 · Journal Article
- Neuregulin-1 positively modulates glial response and improves neurological recovery following traumatic spinal cord injury. — PubMed · 2017 · Journal Article
- Spinal cord injury in hypertonic newborns after antenatal hypoxia-ischemia in a rabbit model of cerebral palsy. — PubMed · 2017 · Journal Article
- Acute granulocyte macrophage-colony stimulating factor treatment modulates neuroinflammatory processes and promotes tactile recovery after spinal cord injury. — PubMed · 2017 · Journal Article
- Deficiency of TREK-1 potassium channel exacerbates secondary injury following spinal cord injury in mice. — PubMed · 2017 · Journal Article
- A modified collagen scaffold facilitates endogenous neurogenesis for acute spinal cord injury repair. — PubMed · 2017 · Journal Article
- A Thermosensitive Heparin-Poloxamer Hydrogel Bridges aFGF to Treat Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Bone marrow stromal cell sheets may promote axonal regeneration and functional recovery with suppression of glial scar formation after spinal cord transection injury in rats. — PubMed · 2017 · Journal Article
- Macrophage Transcriptional Profile Identifies Lipid Catabolic Pathways That Can Be Therapeutically Targeted after Spinal Cord Injury. — PubMed · 2017 · Journal Article
- Periostin Promotes Scar Formation through the Interaction between Pericytes and Infiltrating Monocytes/Macrophages after Spinal Cord Injury. — PubMed · 2017 · Journal Article
- RhoA knockdown by cationic amphiphilic copolymer/siRhoA polyplexes enhances axonal regeneration in rat spinal cord injury model. — PubMed · 2017 · Journal Article
- Spatiotemporal expression of Ski after rat spinal cord injury. — PubMed · 2017 · Journal Article
- Experimental Zika virus infection induces spinal cord injury and encephalitis in newborn Swiss mice. — PubMed · 2017 · Journal Article
- The combination of db-cAMP and ChABC with poly(propylene carbonate) microfibers promote axonal regenerative sprouting and functional recovery after spinal cord hemisection injury. — PubMed · 2017 · Journal Article
- A Novel Rac1-GSPT1 Signaling Pathway Controls Astrogliosis Following Central Nervous System Injury. — PubMed · 2017 · Journal Article
- Ependymal cell contribution to scar formation after spinal cord injury is minimal, local and dependent on direct ependymal injury. — PubMed · 2017 · Journal Article
- The systematic analysis of coding and long non-coding RNAs in the sub-chronic and chronic stages of spinal cord injury. — PubMed · 2017 · Journal Article
- Curcumin inhibits glial scar formation by suppressing astrocyte-induced inflammation and fibrosis in vitro and in vivo. — PubMed · 2017 · Journal Article
- Immunization with neural derived peptides plus scar removal induces a permissive microenvironment, and improves locomotor recovery after chronic spinal cord injury. — PubMed · 2017 · Journal Article
- MiR-17 targets PTEN and facilitates glial scar formation after spinal cord injuries via the PI3K/Akt/mTOR pathway. — PubMed · 2017 · Journal Article
- Sulfatase-mediated manipulation of the astrocyte-Schwann cell interface. — PubMed · 2017 · Journal Article
- Whole body vibration (WBV) following spinal cord injury (SCI) in rats: Timing of intervention. — PubMed · 2017 · Journal Article
- Combined treatment with chondroitinase ABC and treadmill rehabilitation for chronic severe spinal cord injury in adult rats. — PubMed · 2016 · Journal Article
- Effects of melatonin on severe crush spinal cord injury-induced reactive astrocyte and scar formation. — PubMed · 2016 · Journal Article
- Astrocytic CCAAT/Enhancer-Binding Protein Delta Contributes to Glial Scar Formation and Impairs Functional Recovery After Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Lentiviral Vector-Mediated p27(kip1) Expression Facilitates Recovery After Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Photodynamic Therapy Mediated by Upconversion Nanoparticles to Reduce Glial Scar Formation and Promote Hindlimb Functional Recovery After Spinal Cord Injury in Rats. — PubMed · 2016 · Research Support, Non-U.S. Gov't
- Regenerative Potential of Ependymal Cells for Spinal Cord Injuries Over Time. — PubMed · 2016 · Journal Article
- Changes in the Expression of miR-34a and its Target Genes Following Spinal Cord Injury In Rats. — PubMed · 2016 · Journal Article
- Neurobiochemical changes in the vicinity of a nanostructured neural implant. — PubMed · 2016 · Journal Article
- Self-assembling Peptide Reduces Glial Scarring, Attenuates Posttraumatic Inflammation, and Promotes Neurite Outgrowth of Spinal Motor Neurons. — PubMed · 2016 · Journal Article
- Spinal cord injury induces astroglial conversion towards neuronal lineage. — PubMed · 2016 · Journal Article
- Combination of grafted Schwann cells and lentiviral-mediated prevention of glial scar formation improve recovery of spinal cord injured rats. — PubMed · 2016 · Journal Article
- Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Is Constitutively Expressed in Adult Central Nervous System (CNS) and Associated with Astrocyte-mediated Glial Scar Formation following Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Self-assembling peptides optimize the post-traumatic milieu and synergistically enhance the effects of neural stem cell therapy after cervical spinal cord injury. — PubMed · 2016 · Journal Article
- Tamoxifen Administration Immediately or 24 Hours after Spinal Cord Injury Improves Locomotor Recovery and Reduces Secondary Damage in Female Rats. — PubMed · 2016 · Journal Article
- Anti-inflammatory effects of ADAMTS-4 in a mouse model of ischemic stroke. — PubMed · 2016 · Journal Article
- Small Molecule Agonists of Cell Adhesion Molecule L1 Mimic L1 Functions In Vivo. — PubMed · 2016 · Journal Article
- Targeting the thrombin receptor modulates inflammation and astrogliosis to improve recovery after spinal cord injury. — PubMed · 2016 · Journal Article
- NB-3 signaling mediates the cross-talk between post-traumatic spinal axons and scar-forming cells. — PubMed · 2016 · Journal Article
- Expression of an Activated Integrin Promotes Long-Distance Sensory Axon Regeneration in the Spinal Cord. — PubMed · 2016 · Journal Article
- Migration of Adipose-derived Mesenchymal Stem Cells Stably Expressing Chondroitinase ABC In vitro. — PubMed · 2016 · Journal Article
- Activation and Regulation of NLRP3 Inflammasome by Intrathecal Application of SDF-1a in a Spinal Cord Injury Model. — PubMed · 2016 · Journal Article
- Adipose-Derived Stem Cells Expressing the Neurogenin-2 Promote Functional Recovery After Spinal Cord Injury in Rat. — PubMed · 2016 · Journal Article
- Attenuated Reactive Gliosis and Enhanced Functional Recovery Following Spinal Cord Injury in Null Mutant Mice of Platelet-Activating Factor Receptor. — PubMed · 2016 · Journal Article
- Hyaluronic acid scaffold has a neuroprotective effect in hemisection spinal cord injury. — PubMed · 2016 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 4 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851162 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 7 · this programme has 1725 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("glial scar" OR "astrogliosis" OR "fibrotic scar") - Crossref
spinal cord injury glial scar astrogliosis - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Gliosis"[MeSH Terms] OR "Cicatrix"[MeSH Terms] OR "glial scar"[Title/Abstract] OR "astrogliosis"[Title/Abstract] OR "fibrotic scar"[Title/Abstract])