A subject this map covers
Glial scar and its remodelling
What belongs here
The tissue that forms around the lesion, and attempts to change it — soften, remodel or use it.
What does not belong here, however close it looks
Skin or soft-tissue scarring after surgery does not belong here.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 478 records · 1963–2026
- Indexed as work in animals: 879 records · 1969–2026
- Indexed as laboratory work: 59 records · 1992–2026
- The source has not said who or what was studied: 294 records · 1983–2026
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1710 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- The Spinal Ependymal Layer in Health and Disease. — PubMed · 2016 · Journal Article
- Absence of gliosis in a teleost model of spinal cord regeneration. — PubMed · 2016 · Journal Article
- An In Situ Gelling Drug Delivery System for Improved Recovery after Spinal Cord Injury. — PubMed · 2016 · Journal Article
- A controlled spinal cord contusion for the rhesus macaque monkey. — PubMed · 2016 · Journal Article
- Mast cells promote scar remodeling and functional recovery after spinal cord injury via mouse mast cell protease 6. — PubMed · 2016 · Journal Article
- STAT3 and SOCS3 regulate NG2 cell proliferation and differentiation after contusive spinal cord injury. — PubMed · 2016 · Journal Article
- Transplantation of neural progenitor cells in chronic spinal cord injury. — PubMed · 2016 · Journal Article
- Tumor necrosis factor superfamily member APRIL contributes to fibrotic scar formation after spinal cord injury. — PubMed · 2016 · Journal Article
- Astrocyte scar formation aids central nervous system axon regeneration. — PubMed · 2016 · Journal Article
- A Hydrogel Bridge Incorporating Immobilized Growth Factors and Neural Stem/Progenitor Cells to Treat Spinal Cord Injury. — PubMed · 2016 · Journal Article
- Soluble epoxide hydrolase inhibition provides multi-target therapeutic effects in rats after spinal cord injury. — PubMed · 2016 · Journal Article
- Administration of low dose estrogen attenuates gliosis and protects neurons in acute spinal cord injury in rats. — PubMed · 2016 · Journal Article
- Reactive astrocytes undergo M1 microglia/macrohpages-induced necroptosis in spinal cord injury. — PubMed · 2016 · Journal Article
- A biocompatibility study of new nanofibrous scaffolds for nervous system regeneration. — PubMed · 2016 · Journal Article
- O-GlcNAc glycosylation of p27(kip1) promotes astrocyte migration and functional recovery after spinal cord contusion. — PubMed · 2015 · Journal Article
- CDK14 Contributes to Reactive Gliosis via Interaction with Cyclin Y in Rat Model of Spinal Cord Injury. — PubMed · 2015 · Journal Article
- Combination therapy of stem cell derived neural progenitors and drug delivery of anti-inhibitory molecules for spinal cord injury. — PubMed · 2015 · Journal Article
- Myeloid-Specific Blockade of Notch Signaling by RBP-J Knockout Attenuates Spinal Cord Injury Accompanied by Compromised Inflammation Response in Mice. — PubMed · 2015 · Journal Article
- Neuronal RARβ Signaling Modulates PTEN Activity Directly in Neurons and via Exosome Transfer in Astrocytes to Prevent Glial Scar Formation and Induce Spinal Cord Regeneration. — PubMed · 2015 · Journal Article
- A functional progesterone receptor is required for immunomodulation, reduction of reactive gliosis and survival of oligodendrocyte precursors in the injured spinal cord. — PubMed · 2015 · Journal Article
- Expression of Peroxiredoxin 1 After Traumatic Spinal Cord Injury in Rats. — PubMed · 2015 · Journal Article
- Genetic targeting of protease activated receptor 2 reduces inflammatory astrogliosis and improves recovery of function after spinal cord injury. — PubMed · 2015 · Journal Article
- A nutrient combination designed to enhance synapse formation and function improves outcome in experimental spinal cord injury. — PubMed · 2015 · Journal Article
- Feasibility Study of Canine Epidermal Neural Crest Stem Cell Transplantation in the Spinal Cords of Dogs. — PubMed · 2015 · Journal Article
- Local Delivery of High-Dose Chondroitinase ABC in the Sub-Acute Stage Promotes Axonal Outgrowth and Functional Recovery after Complete Spinal Cord Transection. — PubMed · 2015 · Journal Article
- Sustained dual drug delivery of anti-inhibitory molecules for treatment of spinal cord injury. — PubMed · 2015 · Journal Article
- The Complement Receptor C5aR Has a Dual, Time-Dependent Effect on the Outcome of Spinal Cord Injury. — PubMed · 2015 · Journal Article
- Local delivery of FTY720 in PCL membrane improves SCI functional recovery by reducing reactive astrogliosis. — PubMed · 2015 · Journal Article
- Remote-controlled eradication of astrogliosis in spinal cord injury via electromagnetically-induced dexamethasone release from "smart" nanowires. — PubMed · 2015 · Journal Article
- Expressing Constitutively Active Rheb in Adult Neurons after a Complete Spinal Cord Injury Enhances Axonal Regeneration beyond a Chondroitinase-Treated Glial Scar. — PubMed · 2015 · Journal Article
- Fibronectin Matrix Assembly after Spinal Cord Injury. — PubMed · 2015 · Journal Article
- Histone acetylation inhibitors promote axon growth in adult dorsal root ganglia neurons. — PubMed · 2015 · Journal Article
- [TRANSPLANTATION OF NEURAL STEM CELLS INDUCED BY ALL-TRANS- RETINOIC ACID COMBINED WITH GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR AND CHONDROITINASE ABC FOR REPAIRING SPINAL CORD INJURY OF RATS]. — PubMed · 2015 · Journal Article
- Spatiotemporal Expression of EAPP Modulates Neuronal Apoptosis and Reactive Astrogliosis After Spinal Cord Injury. — PubMed · 2015 · Journal Article
- CB1 cannabinoid receptor agonist inhibits matrix metalloproteinase activity in spinal cord injury: A possible mechanism of improved recovery. — PubMed · 2015 · Journal Article
- Crosstalk between macrophages and astrocytes affects proliferation, reactive phenotype and inflammatory response, suggesting a role during reactive gliosis following spinal cord injury. — PubMed · 2015 · Journal Article
- Different Astrocytic Activation between Adult Gekko japonicus and Rats during Wound Healing In Vitro. — PubMed · 2015 · Journal Article
- Curcumin improves neural function after spinal cord injury by the joint inhibition of the intracellular and extracellular components of glial scar. — PubMed · 2015 · Journal Article
- Histamine promotes locomotion recovery after spinal cord hemisection via inhibiting astrocytic scar formation. — PubMed · 2015 · Journal Article
- shRNA against PTEN promotes neurite outgrowth of cortical neurons and functional recovery in spinal cord contusion rats. — PubMed · 2015 · Journal Article
- The Complement Receptor C5aR Controls Acute Inflammation and Astrogliosis following Spinal Cord Injury. — PubMed · 2015 · Journal Article
- Vimentin regulates neuroplasticity in transected spinal cord rats associated with micRNA138. — PubMed · 2015 · Journal Article
- Antisense vimentin cDNA combined with chondroitinase ABC promotes axon regeneration and functional recovery following spinal cord injury in rats. — PubMed · 2015 · Journal Article
- β1-Integrin alters ependymal stem cell BMP receptor localization and attenuates astrogliosis after spinal cord injury. — PubMed · 2015 · Journal Article
- Decreased anti-regenerative effects after spinal cord injury in spry4-/- mice. — PubMed · 2015 · Journal Article
- Effect of nimodipine on rat spinal cord injury. — PubMed · 2015 · Journal Article
- Crmp4 deletion promotes recovery from spinal cord injury by neuroprotection and limited scar formation. — PubMed · 2015 · Journal Article
- Hematogenous macrophage depletion reduces the fibrotic scar and increases axonal growth after spinal cord injury. — PubMed · 2015 · Journal Article
- Interleukin-33 treatment reduces secondary injury and improves functional recovery after contusion spinal cord injury. — PubMed · 2015 · Journal Article
- MicroRNA-145 as one negative regulator of astrogliosis. — PubMed · 2015 · Journal Article
- Axonal regeneration through the fibrous scar in lesioned goldfish spinal cord. — PubMed · 2015 · Journal Article
- Chronic oligodendrogenesis and remyelination after spinal cord injury in mice and rats. — PubMed · 2015 · Journal Article
- Galectin-1 in injured rat spinal cord: implications for macrophage phagocytosis and neural repair. — PubMed · 2015 · Journal Article
- Inhibition of glial proliferation, promotion of axonal growth and myelin production by synthetic glycolipid: A new approach for spinal cord injury treatment. — PubMed · 2015 · Journal Article
- Lentiviral-mediated silencing of glial fibrillary acidic protein and vimentin promotes anatomical plasticity and functional recovery after spinal cord injury. — PubMed · 2015 · Journal Article
- MMP9-sensitive polymers mediate environmentally-responsive bivalirudin release and thrombin inhibition. — PubMed · 2015 · Journal Article
- Pharmacologically inhibiting kinesin-5 activity with monastrol promotes axonal regeneration following spinal cord injury. — PubMed · 2015 · Journal Article
- The regulation of Sox2 and Sox9 stimulated by ATP in spinal cord astrocytes. — PubMed · 2015 · Journal Article
- Transforming growth factor β-induced expression of chondroitin sulfate proteoglycans is mediated through non-Smad signaling pathways. — PubMed · 2015 · Journal Article
- Transient activation of an adaptor protein, disabled-2, in rat spinal cord injury. — PubMed · 2015 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 4 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851162 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 7 · this programme has 1725 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("glial scar" OR "astrogliosis" OR "fibrotic scar") - Crossref
spinal cord injury glial scar astrogliosis - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Gliosis"[MeSH Terms] OR "Cicatrix"[MeSH Terms] OR "glial scar"[Title/Abstract] OR "astrogliosis"[Title/Abstract] OR "fibrotic scar"[Title/Abstract])