A subject this map covers
Glial scar and its remodelling
What belongs here
The tissue that forms around the lesion, and attempts to change it — soften, remodel or use it.
What does not belong here, however close it looks
Skin or soft-tissue scarring after surgery does not belong here.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 478 records · 1963–2026
- Indexed as work in animals: 879 records · 1969–2026
- Indexed as laboratory work: 59 records · 1992–2026
- The source has not said who or what was studied: 294 records · 1983–2026
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1710 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Blockade of gap junction hemichannel protects secondary spinal cord injury from activated microglia-mediated glutamate exitoneurotoxicity. — PubMed · 2014 · Journal Article
- Brilliant blue G treatment facilitates regeneration after optic nerve injury in the adult rat. — PubMed · 2014 · Journal Article
- Entrapment via synaptic-like connections between NG2 proteoglycan+ cells and dystrophic axons in the lesion plays a role in regeneration failure after spinal cord injury. — PubMed · 2014 · Journal Article
- Decreased GFAP expression and improved functional recovery in contused spinal cord of rats following valproic acid therapy. — PubMed · 2014 · Journal Article
- Effects of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor on glial scar formation after spinal cord injury in rats. — PubMed · 2014 · Journal Article
- Functional requirement of dicer1 and miR-17-5p in reactive astrocyte proliferation after spinal cord injury in the mouse. — PubMed · 2014 · Journal Article
- Mn porphyrin-based SOD mimic, MnTnHex-2-PyP(5+), and non-SOD mimic, MnTBAP(3-), suppressed rat spinal cord ischemia/reperfusion injury via NF-κB pathways. — PubMed · 2014 · Journal Article
- Oncostatin M reduces lesion size and promotes functional recovery and neurite outgrowth after spinal cord injury. — PubMed · 2014 · Journal Article
- Evaluation of the effect of tranilast on rats with spinal cord injury. — PubMed · 2014 · Journal Article
- Transplantation of mature adipocyte-derived dedifferentiated fat cells promotes locomotor functional recovery by remyelination and glial scar reduction after spinal cord injury in mice. — PubMed · 2014 · Journal Article
- An acute growth factor treatment that preserves function after spinal cord contusion injury. — PubMed · 2014 · Journal Article
- Aromatase inhibition exacerbates pain and reactive gliosis in the dorsal horn of the spinal cord of female rats caused by spinothalamic tract injury. — PubMed · 2014 · Journal Article
- Expression of SGTA correlates with neuronal apoptosis and reactive gliosis after spinal cord injury. — PubMed · 2014 · Journal Article
- Global gene expression analysis following spinal cord injury in non-human primates. — PubMed · 2014 · Journal Article
- Examination of the combined effects of chondroitinase ABC, growth factors and locomotor training following compressive spinal cord injury on neuroanatomical plasticity and kinematics. — PubMed · 2014 · Journal Article
- Targeting RPTPσ with lentiviral shRNA promotes neurites outgrowth of cortical neurons and improves functional recovery in a rat spinal cord contusion model. — PubMed · 2014 · Journal Article
- Neural precursor cell transplantation enhances functional recovery and reduces astrogliosis in bilateral compressive/contusive cervical spinal cord injury. — PubMed · 2014 · Journal Article
- Tegaserod, a small compound mimetic of polysialic acid, promotes functional recovery after spinal cord injury in mice. — PubMed · 2014 · Journal Article
- Fibronectin enhances spinal cord astrocyte proliferation by elevating P2Y1 receptor expression. — PubMed · 2014 · Journal Article
- Molecular hydrogen suppresses reactive astrogliosis related to oxidative injury during spinal cord injury in rats. — PubMed · 2014 · Journal Article
- Repair of the injured spinal cord by implantation of a synthetic degradable block copolymer in rat. — PubMed · 2014 · Journal Article
- Long-lasting significant functional improvement in chronic severe spinal cord injury following scar resection and polyethylene glycol implantation. — PubMed · 2014 · Journal Article
- Administration of microRNA-210 promotes spinal cord regeneration in mice. — PubMed · 2014 · Journal Article
- Neuronal deletion of GSK3β increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2. — PubMed · 2014 · Journal Article
- Aquaporin-4 mitigates retrograde degeneration of rubrospinal neurons by facilitating edema clearance and glial scar formation after spinal cord injury in mice. — PubMed · 2014 · Journal Article
- Precise control of miR-125b levels is required to create a regeneration-permissive environment after spinal cord injury: a cross-species comparison between salamander and rat. — PubMed · 2014 · Comparative Study
- Prevention effect of medical self-crosslinking sodium hyaluronate gel on epidural scar adhesion after laminectomy. — PubMed · 2014 · Journal Article
- Astrocytic and vascular remodeling in the injured adult rat spinal cord after chondroitinase ABC treatment. — PubMed · 2014 · Journal Article
- Epidermal growth factor receptor inhibitor ameliorates excessive astrogliosis and improves the regeneration microenvironment and functional recovery in adult rats following spinal cord injury. — PubMed · 2014 · Journal Article
- Effects of neuropeptides and their local administration to cutaneous wounds in sensory-impaired areas. — PubMed · 2014 · Journal Article
- High-resolution intravital imaging reveals that blood-derived macrophages but not resident microglia facilitate secondary axonal dieback in traumatic spinal cord injury. — PubMed · 2014 · Journal Article
- Interleukin-6 secretion by astrocytes is dynamically regulated by PI3K-mTOR-calcium signaling. — PubMed · 2014 · Journal Article
- Does Nrf2 gene transfer facilitate recovery after contusion spinal cord injury? — PubMed · 2014 · Journal Article
- Effects of polyethylene glycol administration and bone marrow stromal cell transplantation therapy in spinal cord injury mice. — PubMed · 2014 · Journal Article
- Fgf2 improves functional recovery-decreasing gliosis and increasing radial glia and neural progenitor cells after spinal cord injury. — PubMed · 2014 · Journal Article
- Synergistic effects of self-assembling peptide and neural stem/progenitor cells to promote tissue repair and forelimb functional recovery in cervical spinal cord injury. — PubMed · 2014 · Journal Article
- Astroglial-derived periostin promotes axonal regeneration after spinal cord injury. — PubMed · 2014 · Journal Article
- Curcumin promotes the spinal cord repair via inhibition of glial scar formation and inflammation. — PubMed · 2014 · Journal Article
- Mast cells protect from post-traumatic spinal cord damage in mice by degrading inflammation-associated cytokines via mouse mast cell protease 4. — PubMed · 2014 · Journal Article
- Neuroprotective ferulic acid (FA)-glycol chitosan (GC) nanoparticles for functional restoration of traumatically injured spinal cord. — PubMed · 2014 · Journal Article
- Scar in the injured spinal cord: the news is not all bad. — PubMed · 2014 · News
- Combination of engineered Schwann cell grafts to secrete neurotrophin and chondroitinase promotes axonal regeneration and locomotion after spinal cord injury. — PubMed · 2014 · Journal Article
- In utero repair of myelomeningocele with autologous amniotic membrane in the fetal lamb model. — PubMed · 2014 · Journal Article
- Mesenchymal stem cell transplantation reduces glial cyst and improves functional outcome after spinal cord compression. — PubMed · 2014 · Journal Article
- Reduction of epidural fibrosis and dural adhesions after lamina reconstruction by absorbable cement: an experimental study. — PubMed · 2014 · Journal Article
- Spinal cord regeneration. — PubMed · 2014 · Journal Article
- Sustained delivery of dbcAMP by poly(propylene carbonate) micron fibers promotes axonal regenerative sprouting and functional recovery after spinal cord hemisection. — PubMed · 2013 · Journal Article
- Transgenic overexpression of the cell adhesion molecule L1 in neurons facilitates recovery after mouse spinal cord injury. — PubMed · 2013 · Journal Article
- Resident neural stem cells restrict tissue damage and neuronal loss after spinal cord injury in mice. — PubMed · 2013 · Journal Article
- Spinal cord injury induced changes of nuclear receptors PPARα and LXRβ and modulation with oleic acid/albumin treatment. — PubMed · 2013 · Journal Article
- Electro-acupuncture treatment improves neurological function associated with downregulation of PDGF and inhibition of astrogliosis in rats with spinal cord transection. — PubMed · 2013 · Journal Article
- Genetically modified mesenchymal stem cells (MSCs) promote axonal regeneration and prevent hypersensitivity after spinal cord injury. — PubMed · 2013 · Journal Article
- A self-assembling peptide reduces glial scarring, attenuates post-traumatic inflammation and promotes neurological recovery following spinal cord injury. — PubMed · 2013 · Journal Article
- Comparison of sensory neuron growth cone and filopodial responses to structurally diverse aggrecan variants, in vitro. — PubMed · 2013 · Journal Article
- Dysregulation of the neuregulin-1-ErbB network modulates endogenous oligodendrocyte differentiation and preservation after spinal cord injury. — PubMed · 2013 · Journal Article
- Role of telomerase reverse transcriptase in glial scar formation after spinal cord injury in rats. — PubMed · 2013 · Journal Article
- Perivascular fibroblasts form the fibrotic scar after contusive spinal cord injury. — PubMed · 2013 · Journal Article
- Different modifications of phosphorylated Smad3C and Smad3L through TGF-β after spinal cord injury in mice. — PubMed · 2013 · Journal Article
- Host reaction to poly(2-hydroxyethyl methacrylate) scaffolds in a small spinal cord injury model. — PubMed · 2013 · Journal Article
- Pericytes as a therapeutic target in scar formation after spinal cord injury. — PubMed · 2013 · News
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 4 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851162 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 7 · this programme has 1725 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("glial scar" OR "astrogliosis" OR "fibrotic scar") - Crossref
spinal cord injury glial scar astrogliosis - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Gliosis"[MeSH Terms] OR "Cicatrix"[MeSH Terms] OR "glial scar"[Title/Abstract] OR "astrogliosis"[Title/Abstract] OR "fibrotic scar"[Title/Abstract])