A subject this map covers
Glial scar and its remodelling
What belongs here
The tissue that forms around the lesion, and attempts to change it — soften, remodel or use it.
What does not belong here, however close it looks
Skin or soft-tissue scarring after surgery does not belong here.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 478 records · 1963–2026
- Indexed as work in animals: 879 records · 1969–2026
- Indexed as laboratory work: 59 records · 1992–2026
- The source has not said who or what was studied: 294 records · 1983–2026
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1710 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Glial scar borders are formed by newly proliferated, elongated astrocytes that interact to corral inflammatory and fibrotic cells via STAT3-dependent mechanisms after spinal cord injury. — PubMed · 2013 · Journal Article
- Cell cycle activation contributes to increased neuronal activity in the posterior thalamic nucleus and associated chronic hyperesthesia after rat spinal cord contusion. — PubMed · 2013 · Journal Article
- Beneficial function of cell division cycle 2 activity in astrocytes on axonal regeneration after spinal cord injury. — PubMed · 2013 · Journal Article
- ADAMTS1, ADAMTS5, ADAMTS9 and aggrecanase-generated proteoglycan fragments are induced following spinal cord injury in mouse. — PubMed · 2013 · Journal Article
- A novel experimental model of cervical spondylotic myelopathy (CSM) to facilitate translational research. — PubMed · 2013 · Journal Article
- Axonal and glial responses to a mid-thoracic spinal cord hemisection in the Macaca fascicularis monkey. — PubMed · 2013 · Journal Article
- Potential of olfactory ensheathing cells from different sources for spinal cord repair. — PubMed · 2013 · Journal Article
- In vivo imaging: a dynamic imaging approach to study spinal cord regeneration. — PubMed · 2013 · Journal Article
- Neuroprotective effect of cocaine- and amphetamine-regulated transcript peptide in spinal cord injury in mice. — PubMed · 2013 · Journal Article
- Resolvin E1 inhibits neuropathic pain and spinal cord microglial activation following peripheral nerve injury. — PubMed · 2013 · Journal Article
- Role of microglia and astrocyte in central pain syndrome following electrolytic lesion at the spinothalamic tract in rats. — PubMed · 2013 · Journal Article
- Alleviation of chronic pain following rat spinal cord compression injury with multimodal actions of huperzine A. — PubMed · 2013 · Journal Article
- A novel compound, denosomin, ameliorates spinal cord injury via axonal growth associated with astrocyte-secreted vimentin. — PubMed · 2013 · Journal Article
- [Effect of chondroitinase ABC on axonal myelination and glial scar after spinal cord injury in rats]. — PubMed · 2013 · English Abstract
- Absence of IL-1β positively affects neurological outcome, lesion development and axonal plasticity after spinal cord injury. — PubMed · 2013 · Journal Article
- Time-dependent changes in the microenvironment of injured spinal cord affects the therapeutic potential of neural stem cell transplantation for spinal cord injury. — PubMed · 2013 · Journal Article
- Exogenous BDNF enhances the integration of chronically injured axons that regenerate through a peripheral nerve grafted into a chondroitinase-treated spinal cord injury site. — PubMed · 2013 · Journal Article
- Immunological demyelination triggers macrophage/microglial cells activation without inducing astrogliosis. — PubMed · 2013 · Journal Article
- Resident glial cell activation in response to perispinal inflammation leads to acute changes in nociceptive sensitivity: implications for the generation of neuropathic pain. — PubMed · 2013 · Journal Article
- The multifaceted effects of agmatine on functional recovery after spinal cord injury through Modulations of BMP-2/4/7 expressions in neurons and glial cells. — PubMed · 2013 · Journal Article
- Bog bilberry anthocyanin extract improves motor functional recovery by multifaceted effects in spinal cord injury. — PubMed · 2012 · Journal Article
- Contribution of bone marrow-derived endothelial progenitor cells to neovascularization and astrogliosis following spinal cord injury. — PubMed · 2012 · Journal Article
- [Experimental study of the correlation of telomerase and intramedullary scar after spinal cord injury in rats]. — PubMed · 2012 · English Abstract
- Lentiviral vector delivery of short hairpin RNA to NG2 and neurotrophin-3 promotes locomotor recovery in injured rat spinal cord. — PubMed · 2012 · Journal Article
- Opposing effects of Toll-like receptors 2 and 4 on synaptic stability in the spinal cord after peripheral nerve injury. — PubMed · 2012 · Journal Article
- p53 Regulates the neuronal intrinsic and extrinsic responses affecting the recovery of motor function following spinal cord injury. — PubMed · 2012 · Journal Article
- Partial change in EphA4 knockout mouse phenotype: loss of diminished GFAP upregulation following spinal cord injury. — PubMed · 2012 · Journal Article
- Postinjury administration of 17β-estradiol induces protection in the gray and white matter with associated functional recovery after cervical spinal cord injury in male rats. — PubMed · 2012 · Journal Article
- Inhibition of EGFR/MAPK signaling reduces microglial inflammatory response and the associated secondary damage in rats after spinal cord injury. — PubMed · 2012 · Journal Article
- Delayed expression of cell cycle proteins contributes to astroglial scar formation and chronic inflammation after rat spinal cord contusion. — PubMed · 2012 · Journal Article
- Endothelial progenitor cells promote astrogliosis following spinal cord injury through Jagged1-dependent Notch signaling. — PubMed · 2012 · Journal Article
- Mechanical characterization of the injured spinal cord after lateral spinal hemisection injury in the rat. — PubMed · 2012 · Journal Article
- Tail nerve electrical stimulation combined with scar ablation and neural transplantation promotes locomotor recovery in rats with chronically contused spinal cord. — PubMed · 2012 · Journal Article
- Ethyl pyruvate promotes spinal cord repair by ameliorating the glial microenvironment. — PubMed · 2012 · Journal Article
- Functional recovery after spinal cord injury in dogs treated with a combination of Matrigel and neural-induced adipose-derived mesenchymal Stem cells. — PubMed · 2012 · Journal Article
- Salmon fibrin treatment of spinal cord injury promotes functional recovery and density of serotonergic innervation. — PubMed · 2012 · Journal Article
- The NAMPT inhibitor FK866 reverts the damage in spinal cord injury. — PubMed · 2012 · Journal Article
- FTY720 improves functional recovery after spinal cord injury by primarily nonimmunomodulatory mechanisms. — PubMed · 2012 · Journal Article
- Spatial and temporal activation of spinal glial cells: role of gliopathy in central neuropathic pain following spinal cord injury in rats. — PubMed · 2012 · Journal Article
- Critical role of connexin 43 in secondary expansion of traumatic spinal cord injury. — PubMed · 2012 · Comparative Study
- Astrogliosis involves activation of retinoic acid-inducible gene-like signaling in the innate immune response after spinal cord injury. — PubMed · 2012 · Journal Article
- The development of a rat in vitro model of spinal cord injury demonstrating the additive effects of Rho and ROCK inhibitors on neurite outgrowth and myelination. — PubMed · 2012 · Journal Article
- Axon-glia synapses are highly vulnerable to white matter injury in the developing brain. — PubMed · 2012 · Journal Article
- BB14, a Nerve Growth Factor (NGF)-like peptide shown to be effective in reducing reactive astrogliosis and restoring synaptic homeostasis in a rat model of peripheral nerve injury. — PubMed · 2012 · Journal Article
- Blockade of P2 nucleotide receptors after spinal cord injury reduced the gliotic response and spared tissue. — PubMed · 2012 · Journal Article
- Chondroitinase and growth factors enhance activation and oligodendrocyte differentiation of endogenous neural precursor cells after spinal cord injury. — PubMed · 2012 · Journal Article
- Early endogenous activation of CB1 and CB2 receptors after spinal cord injury is a protective response involved in spontaneous recovery. — PubMed · 2012 · Journal Article
- Imatinib enhances functional outcome after spinal cord injury. — PubMed · 2012 · Journal Article
- Promotion of spinal cord regeneration by neural stem cell-secreted trimerized cell adhesion molecule L1. — PubMed · 2012 · Journal Article
- Effect of laser phototherapy on wound healing following cerebral ischemia by cryogenic injury. — PubMed · 2011 · Journal Article
- Agmatine-reduced collagen scar area accompanied with surface righting reflex recovery after complete transection spinal cord injury. — PubMed · 2011 · Journal Article
- A pilot study of poly(N-isopropylacrylamide)-g-polyethylene glycol and poly(N-isopropylacrylamide)-g-methylcellulose branched copolymers as injectable scaffolds for local delivery of neurotrophins and cellular transplants into the injured spinal cord. — PubMed · 2011 · Journal Article
- Nestin- and doublecortin-positive cells reside in adult spinal cord meninges and participate in injury-induced parenchymal reaction. — PubMed · 2011 · Journal Article
- Reduction in expression of the astrocyte glutamate transporter, GLT1, worsens functional and histological outcomes following traumatic spinal cord injury. — PubMed · 2011 · Journal Article
- Axonal regrowth after spinal cord injury via chondroitinase and the tissue plasminogen activator (tPA)/plasmin system. — PubMed · 2011 · Journal Article
- A comparative histological analysis of two models of nerve root avulsion injury in the adult rat. — PubMed · 2011 · Journal Article
- Regulation of chondroitin sulphate proteoglycan and reactive gliosis after spinal cord transection: effects of peripheral nerve graft and fibroblast growth factor 1. — PubMed · 2011 · Journal Article
- The inhibitory effects of chondroitin sulfate proteoglycans on oligodendrocytes. — PubMed · 2011 · Journal Article
- Starting the scar: a primary role for pericytes? — PubMed · 2011 · Journal Article
- Progesterone attenuates astro- and microgliosis and enhances oligodendrocyte differentiation following spinal cord injury. — PubMed · 2011 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 4 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851162 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 7 · this programme has 1725 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("glial scar" OR "astrogliosis" OR "fibrotic scar") - Crossref
spinal cord injury glial scar astrogliosis - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Gliosis"[MeSH Terms] OR "Cicatrix"[MeSH Terms] OR "glial scar"[Title/Abstract] OR "astrogliosis"[Title/Abstract] OR "fibrotic scar"[Title/Abstract])