A subject this map covers
Glial scar and its remodelling
What belongs here
The tissue that forms around the lesion, and attempts to change it — soften, remodel or use it.
What does not belong here, however close it looks
Skin or soft-tissue scarring after surgery does not belong here.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 478 records · 1963–2026
- Indexed as work in animals: 879 records · 1969–2026
- Indexed as laboratory work: 59 records · 1992–2026
- The source has not said who or what was studied: 294 records · 1983–2026
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1710 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Transplanted L1 expressing radial glia and astrocytes enhance recovery after spinal cord injury. — PubMed · 2011 · Journal Article
- Delayed paraplegia after spinal cord ischemic injury requires caspase-3 activation in mice. — PubMed · 2011 · Journal Article
- High molecular weight hyaluronic acid limits astrocyte activation and scar formation after spinal cord injury. — PubMed · 2011 · Journal Article
- A pericyte origin of spinal cord scar tissue. — PubMed · 2011 · Journal Article
- Scar ablation combined with LP/OEC transplantation promotes anatomical recovery and P0-positive myelination in chronically contused spinal cord of rats. — PubMed · 2011 · Journal Article
- Combination of NEP 1-40 infusion and bone marrow-derived neurospheres transplantation inhibit glial scar formation and promote functional recovery after rat spinal cord injury. — PubMed · 2011 · Journal Article
- Early graft of neural precursors in spinal cord compression reduces glial cyst and improves function. — PubMed · 2011 · Journal Article
- Inhibiting epidermal growth factor receptor attenuates reactive astrogliosis and improves functional outcome after spinal cord injury in rats. — PubMed · 2011 · Journal Article
- Reactive astrocytes inhibit the survival and differentiation of oligodendrocyte precursor cells by secreted TNF-α. — PubMed · 2011 · Journal Article
- Peptide-modified inverted colloidal crystal scaffolds with bone marrow stromal cells in the treatment for spinal cord injury. — PubMed · 2011 · Journal Article
- Reaction of endogenous progenitor cells in a rat model of posttraumatic syringomyelia. — PubMed · 2011 · Journal Article
- The unusual response of serotonergic neurons after CNS Injury: lack of axonal dieback and enhanced sprouting within the inhibitory environment of the glial scar. — PubMed · 2011 · Journal Article
- Decorin, erythroblastic leukaemia viral oncogene homologue B4 and signal transducer and activator of transcription 3 regulation of semaphorin 3A in central nervous system scar tissue. — PubMed · 2011 · Journal Article
- Microtubule stabilization reduces scarring and causes axon regeneration after spinal cord injury. — PubMed · 2011 · Journal Article
- Down-regulation of glutamine synthetase enhances migration of rat astrocytes after in vitro injury. — PubMed · 2011 · Journal Article
- Sustained delivery of activated Rho GTPases and BDNF promotes axon growth in CSPG-rich regions following spinal cord injury. — PubMed · 2011 · Journal Article
- Comparison of canine umbilical cord blood-derived mesenchymal stem cell transplantation times: involvement of astrogliosis, inflammation, intracellular actin cytoskeleton pathways, and neurotrophin-3. — PubMed · 2011 · Journal Article
- Immunohistochemical analysis of TIMP-2 and collagen types I and IV in experimental spinal cord ischemia-reperfusion injury in rats. — PubMed · 2011 · Journal Article
- The glial scar-monocyte interplay: a pivotal resolution phase in spinal cord repair. — PubMed · 2011 · Journal Article
- Spinal cord injury-induced astrocyte migration and glial scar formation: effects of magnetic stimulation frequency. — PubMed · 2010 · Journal Article
- Characterization of a graded cervical hemicontusion spinal cord injury model in adult male rats. — PubMed · 2010 · Journal Article
- [Effect of chondroitinase ABC on growth associate protein 43 and glial fibrillary acidic protein after spinal cord injury in rats]. — PubMed · 2010 · English Abstract
- Hyaluronic acid hydrogel modified with nogo-66 receptor antibody and poly-L-lysine to promote axon regrowth after spinal cord injury. — PubMed · 2010 · Journal Article
- Neuropathological differences between rats and mice after spinal cord injury. — PubMed · 2010 · Journal Article
- P2Y2 receptor expression is altered in rats after spinal cord injury. — PubMed · 2010 · Journal Article
- "Tissue-repairing" blood-derived macrophages are essential for healing of the injured spinal cord: from skin-activated macrophages to infiltrating blood-derived cells? — PubMed · 2010 · Journal Article
- ATP-mediated protein kinase B Akt/mammalian target of rapamycin mTOR/p70 ribosomal S6 protein p70S6 kinase signaling pathway activation promotes improvement of locomotor function after spinal cord injury in rats. — PubMed · 2010 · Journal Article
- The pathogenesis and treatment of acute spinal cord injuries in dogs. — PubMed · 2010 · Journal Article
- Extensive scarring induced by chronic intrathecal tubing augmented cord tissue damage and worsened functional recovery after rat spinal cord injury. — PubMed · 2010 · Journal Article
- Glial scar and neuroregeneration: histological, functional, and magnetic resonance imaging analysis in chronic spinal cord injury. — PubMed · 2010 · Journal Article
- Chondroitin sulfate-binding peptides block chondroitin 6-sulfate inhibition of cortical neurite growth. — PubMed · 2010 · Journal Article
- NCAM-mediated locomotor recovery from spinal cord contusion injury involves neuroprotection, axon regeneration, and synaptogenesis. — PubMed · 2010 · Journal Article
- EphA4 deficient mice maintain astroglial-fibrotic scar formation after spinal cord injury. — PubMed · 2010 · Journal Article
- Triptolide promotes spinal cord repair by inhibiting astrogliosis and inflammation. — PubMed · 2010 · Journal Article
- Differentiation of endogenous progenitors in an animal model of post-traumatic syringomyelia. — PubMed · 2010 · Journal Article
- Eph receptor tyrosine kinases regulate astrocyte cytoskeletal rearrangement and focal adhesion formation. — PubMed · 2010 · Journal Article
- Role of early surgical decompression of the intradural space after cervical spinal cord injury in an animal model. — PubMed · 2010 · Journal Article
- Regional heterogeneity in astrocyte responses following contusive spinal cord injury in mice. — PubMed · 2010 · Journal Article
- Separation of the perivascular basement membrane provides a conduit for inflammatory cells in a mouse spinal cord injury model. — PubMed · 2010 · Journal Article
- Gait analysis of spinal cord injured rats after delivery of chondroitinase ABC and adult olfactory mucosa progenitor cell transplantation. — PubMed · 2010 · Journal Article
- Corticospinal tract regeneration after spinal cord injury in receptor protein tyrosine phosphatase sigma deficient mice. — PubMed · 2010 · Journal Article
- Neuronal and axonal degeneration in experimental spinal cord injury: in vivo proton magnetic resonance spectroscopy and histology. — PubMed · 2010 · Journal Article
- Tamoxifen alleviates irradiation-induced brain injury by attenuating microglial inflammatory response in vitro and in vivo. — PubMed · 2010 · Journal Article
- BMPR1a and BMPR1b signaling exert opposing effects on gliosis after spinal cord injury. — PubMed · 2010 · Journal Article
- Synergistic effects of transplanted adult neural stem/progenitor cells, chondroitinase, and growth factors promote functional repair and plasticity of the chronically injured spinal cord. — PubMed · 2010 · Journal Article
- Lnk deletion reinforces the function of bone marrow progenitors in promoting neovascularization and astrogliosis following spinal cord injury. — PubMed · 2010 · Journal Article
- Phosphatidylinositol 3-kinase/protein kinase Cdelta activation induces close homolog of adhesion molecule L1 (CHL1) expression in cultured astrocytes. — PubMed · 2010 · Journal Article
- Adult NG2+ cells are permissive to neurite outgrowth and stabilize sensory axons during macrophage-induced axonal dieback after spinal cord injury. — PubMed · 2010 · Comparative Study
- Reactive astrocytes in glial scar attract olfactory ensheathing cells migration by secreted TNF-alpha in spinal cord lesion of rat. — PubMed · 2009 · Journal Article
- Inhibition of TGF-beta1 promotes functional recovery after spinal cord injury. — PubMed · 2009 · Journal Article
- Combining peripheral nerve grafts and chondroitinase promotes functional axonal regeneration in the chronically injured spinal cord. — PubMed · 2009 · Journal Article
- Activation of p-38alpha MAPK contributes to neuronal hyperexcitability in caudal regions remote from spinal cord injury. — PubMed · 2009 · Journal Article
- Enhanced regenerative axon growth of multiple fibre populations in traumatic spinal cord injury following scar-suppressing treatment. — PubMed · 2009 · Journal Article
- Importance of the vasculature in cyst formation after spinal cord injury. — PubMed · 2009 · Journal Article
- Preconditioning selective ventral root injury promotes plasticity of ascending sensory neurons in the injured spinal cord of adult rats--possible roles of brain-derived neurotrophic factor, TrkB and p75 neurotrophin receptor. — PubMed · 2009 · Journal Article
- A polysialic acid mimetic peptide promotes functional recovery in a mouse model of spinal cord injury. — PubMed · 2009 · Journal Article
- Embryonic and adult stem cells promote raphespinal axon outgrowth and improve functional outcome following spinal hemisection in mice. — PubMed · 2009 · Comparative Study
- Overcoming macrophage-mediated axonal dieback following CNS injury. — PubMed · 2009 · Journal Article
- Neuroprotective effect of Scutellaria baicalensis on spinal cord injury in rats. — PubMed · 2009 · Journal Article
- Shengmai-san-mediated enhancement of regenerative responses of spinal cord axons after injury in rats. — PubMed · 2009 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 4 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851162 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 7 · this programme has 1725 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("glial scar" OR "astrogliosis" OR "fibrotic scar") - Crossref
spinal cord injury glial scar astrogliosis - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Gliosis"[MeSH Terms] OR "Cicatrix"[MeSH Terms] OR "glial scar"[Title/Abstract] OR "astrogliosis"[Title/Abstract] OR "fibrotic scar"[Title/Abstract])