A subject this map covers
Glial scar and its remodelling
What belongs here
The tissue that forms around the lesion, and attempts to change it — soften, remodel or use it.
What does not belong here, however close it looks
Skin or soft-tissue scarring after surgery does not belong here.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 478 records · 1963–2026
- Indexed as work in animals: 879 records · 1969–2026
- Indexed as laboratory work: 59 records · 1992–2026
- The source has not said who or what was studied: 294 records · 1983–2026
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1710 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Neural reconnection in the transected spinal cord of the freshwater turtle Trachemys dorbignyi. — PubMed · 2009 · Journal Article
- Muscle injection of AAV-NT3 promotes anatomical reorganization of CST axons and improves behavioral outcome following SCI. — PubMed · 2009 · Journal Article
- Expression of the repulsive guidance molecule RGM and its receptor neogenin after spinal cord injury in sea lamprey. — PubMed · 2009 · Journal Article
- The role of thrombospondin-1 and transforming growth factor-beta after spinal cord injury in the rat. — PubMed · 2009 · Journal Article
- Vaccination with dendritic cells pulsed with homogenate protein of spinal cord promotes functional recovery from spinal cord injury in mice. — PubMed · 2009 · Journal Article
- Gene expression profiling in anti-CD11d mAb-treated spinal cord-injured rats. — PubMed · 2009 · Journal Article
- GM-CSF inhibits glial scar formation and shows long-term protective effect after spinal cord injury. — PubMed · 2009 · Journal Article
- Length-scale mediated adhesion and directed growth of neural cells by surface-patterned poly(ethylene glycol) hydrogels. — PubMed · 2009 · Journal Article
- The Rheb-mTOR pathway is upregulated in reactive astrocytes of the injured spinal cord. — PubMed · 2009 · Journal Article
- Corticosteroids reduce glial fibrillary acidic protein expression in response to spinal cord injury in a fetal rat model of dysraphism. — PubMed · 2009 · Journal Article
- Neuropathic pain behaviours in a chronic-relapsing model of experimental autoimmune encephalomyelitis (EAE). — PubMed · 2009 · Journal Article
- Type I interferon inhibits astrocytic gliosis and promotes functional recovery after spinal cord injury by deactivation of the MEK/ERK pathway. — PubMed · 2009 · Journal Article
- X-ray exposure induces apoptosis of some proliferative epidermal cells following traumatic spinal cord injury in adult rats. — PubMed · 2009 · Journal Article
- The yellow fluorescent protein (YFP-H) mouse reveals neuroprotection as a novel mechanism underlying chondroitinase ABC-mediated repair after spinal cord injury. — PubMed · 2008 · Journal Article
- Deficiency in complement C1q improves histological and functional locomotor outcome after spinal cord injury. — PubMed · 2008 · Journal Article
- Antisense vimentin cDNA combined with chondroitinase ABC reduces glial scar and cystic cavity formation following spinal cord injury in rats. — PubMed · 2008 · Journal Article
- Matrix metalloproteinase-9 facilitates glial scar formation in the injured spinal cord. — PubMed · 2008 · Journal Article
- A new in vitro model of the glial scar inhibits axon growth. — PubMed · 2008 · Journal Article
- TGF-alpha increases astrocyte invasion and promotes axonal growth into the lesion following spinal cord injury in mice. — PubMed · 2008 · Journal Article
- Robust axonal growth and a blunted macrophage response are associated with impaired functional recovery after spinal cord injury in the MRL/MpJ mouse. — PubMed · 2008 · Comparative Study
- Another barrier to regeneration in the CNS: activated macrophages induce extensive retraction of dystrophic axons through direct physical interactions. — PubMed · 2008 · Journal Article
- Schwann cell precursors transplanted into the injured spinal cord multiply, integrate and are permissive for axon growth. — PubMed · 2008 · Comparative Study
- Role of Rho kinase pathway in chondroitin sulfate proteoglycan-mediated inhibition of neurite outgrowth in PC12 cells. — PubMed · 2008 · Journal Article
- STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury. — PubMed · 2008 · Journal Article
- The dual role of tumor necrosis factor-alpha in the pathophysiology of spinal cord injury. — PubMed · 2008 · Journal Article
- Connexin 43 mimetic peptides reduce swelling, astrogliosis, and neuronal cell death after spinal cord injury. — PubMed · 2008 · Journal Article
- Intraspinal microinjection of chondroitinase ABC following injury promotes axonal regeneration out of a peripheral nerve graft bridge. — PubMed · 2008 · Journal Article
- Temporal-spatial expressions of p27kip1 and its phosphorylation on Serine-10 after acute spinal cord injury in adult rat: Implications for post-traumatic glial proliferation. — PubMed · 2008 · Journal Article
- Self-assembling nanofibers inhibit glial scar formation and promote axon elongation after spinal cord injury. — PubMed · 2008 · Journal Article
- Greatly improved neurological outcome after spinal cord compression injury in AQP4-deficient mice. — PubMed · 2008 · Journal Article
- Mechanistic insights into posttraumatic syringomyelia based on a novel in vivo animal model. Laboratory investigation. — PubMed · 2008 · Journal Article
- Combined treatment using peripheral nerve graft and FGF-1: changes to the glial environment and differential macrophage reaction in a complete transected spinal cord. — PubMed · 2008 · Journal Article
- tPA-mediated generation of plasmin is catalyzed by the proteoglycan NG2. — PubMed · 2008 · Journal Article
- Axon regeneration after spinal cord injury: insight from genetically modified mouse models. — PubMed · 2008 · Journal Article
- Immunocytochemical characterization of astrocytosis along the spinal cord of loop-tail/curly-tail mice with myelomeningocele. — PubMed · 2008 · Journal Article
- Immunomodulatory effect of the purine nucleoside inosine following spinal cord contusion injury in rat. — PubMed · 2008 · Journal Article
- Potential utility of aquaporin modulators for therapy of brain disorders. — PubMed · 2008 · Journal Article
- Selenium attenuates ROS-mediated apoptotic cell death of injured spinal cord through prevention of mitochondria dysfunction; in vitro and in vivo study. — PubMed · 2008 · Journal Article
- Adult neurogenesis in primate and rodent spinal cord: comparing a cervical dorsal rhizotomy with a dorsal column transection. — PubMed · 2007 · Comparative Study
- Cell cycle activation contributes to post-mitotic cell death and secondary damage after spinal cord injury. — PubMed · 2007 · Journal Article
- Annexin A1 reduces inflammatory reaction and tissue damage through inhibition of phospholipase A2 activation in adult rats following spinal cord injury. — PubMed · 2007 · Journal Article
- Neuronal populations capable of regeneration following a combined treatment in rats with spinal cord transection. — PubMed · 2007 · Journal Article
- Caspase-3 activity is reduced after spinal cord injury in mice lacking dynorphin: differential effects on glia and neurons. — PubMed · 2007 · Journal Article
- Transcriptional regulation of scar gene expression in primary astrocytes. — PubMed · 2007 · Journal Article
- Lithium enhances proliferation and neuronal differentiation of neural progenitor cells in vitro and after transplantation into the adult rat spinal cord. — PubMed · 2007 · Journal Article
- Sensory afferents regenerated into dorsal columns after spinal cord injury remain in a chronic pathophysiological state. — PubMed · 2007 · Journal Article
- Spinal pathways involved in the control of forelimb motor function in rats. — PubMed · 2007 · Journal Article
- Glial scar expression of CHL1, the close homolog of the adhesion molecule L1, limits recovery after spinal cord injury. — PubMed · 2007 · Comparative Study
- Cytoplasmic extracts from adipose tissue stromal cells alleviates secondary damage by modulating apoptosis and promotes functional recovery following spinal cord injury. — PubMed · 2007 · Journal Article
- Toll-like receptor (TLR)-2 and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury. — PubMed · 2007 · Journal Article
- Attenuation of astrogliosis by suppressing of microglial proliferation with the cell cycle inhibitor olomoucine in rat spinal cord injury model. — PubMed · 2007 · Journal Article
- Induced expression of polysialic acid in the spinal cord promotes regeneration of sensory axons. — PubMed · 2007 · Journal Article
- Prominent oligodendrocyte genesis along the border of spinal contusion lesions. — PubMed · 2007 · Journal Article
- Transplantation of preconditioned Schwann cells following hemisection spinal cord injury. — PubMed · 2007 · Evaluation Study
- Cell cycle inhibition attenuates microglia induced inflammatory response and alleviates neuronal cell death after spinal cord injury in rats. — PubMed · 2007 · Journal Article
- Thiazolidinedione class of peroxisome proliferator-activated receptor gamma agonists prevents neuronal damage, motor dysfunction, myelin loss, neuropathic pain, and inflammation after spinal cord injury in adult rats. — PubMed · 2007 · Journal Article
- Functional axonal regeneration through astrocytic scar genetically modified to digest chondroitin sulfate proteoglycans. — PubMed · 2007 · Journal Article
- Chronic transplantation of olfactory ensheathing cells promotes partial recovery after complete spinal cord transection in the rat. — PubMed · 2007 · Journal Article
- Photochemical scar ablation in chronically contused spinal cord of rat. — PubMed · 2007 · Journal Article
- Proinflammatory cytokine synthesis in the injured mouse spinal cord: multiphasic expression pattern and identification of the cell types involved. — PubMed · 2007 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-09-29 | the source found 0 · this programme has 4 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851162 · this programme has 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 7 · this programme has 1725 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("glial scar" OR "astrogliosis" OR "fibrotic scar") - Crossref
spinal cord injury glial scar astrogliosis - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Gliosis"[MeSH Terms] OR "Cicatrix"[MeSH Terms] OR "glial scar"[Title/Abstract] OR "astrogliosis"[Title/Abstract] OR "fibrotic scar"[Title/Abstract])