A subject this map covers
Glial scar and its remodelling
What belongs here
The tissue that forms around the lesion, and attempts to change it — soften, remodel or use it.
What does not belong here, however close it looks
Skin or soft-tissue scarring after surgery does not belong here.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 478 records · 1963–2026
- Indexed as work in animals: 879 records · 1969–2026
- Indexed as laboratory work: 59 records · 1992–2026
- The source has not said who or what was studied: 294 records · 1983–2026
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1710 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Axon regeneration through scars and into sites of chronic spinal cord injury. — PubMed · 2007 · Journal Article
- Neutralization of ciliary neurotrophic factor reduces astrocyte production from transplanted neural stem cells and promotes regeneration of corticospinal tract fibers in spinal cord injury. — PubMed · 2006 · Journal Article
- Positioned to inhibit: netrin-1 and netrin receptor expression after spinal cord injury. — PubMed · 2006 · Journal Article
- The role of spinal tissue scarring in the pathogenesis of progressive post-traumatic myelomalacia. — PubMed · 2006 · Journal Article
- Transplantation of fibroblasts that overexpress matrix metalloproteinase-3 into the site of spinal cord injury in rats. — PubMed · 2006 · Journal Article
- Intraspinal administration of an antibody against CD81 enhances functional recovery and tissue sparing after experimental spinal cord injury. — PubMed · 2006 · Comparative Study
- Transplantation of preconditioned schwann cells in peripheral nerve grafts after contusion in the adult spinal cord. Improvement of recovery in a rat model. — PubMed · 2006 · Journal Article
- An injectable, biodegradable hydrogel for trophic factor delivery enhances axonal rewiring and improves performance after spinal cord injury. — PubMed · 2006 · Journal Article
- Suppression of astroglial scar formation and enhanced axonal regeneration associated with functional recovery in a spinal cord injury rat model by the cell cycle inhibitor olomoucine. — PubMed · 2006 · Comparative Study
- Matrix metalloproteinase-2 facilitates wound healing events that promote functional recovery after spinal cord injury. — PubMed · 2006 · Journal Article
- Delivery of neurotrophin-3 from fibrin enhances neuronal fiber sprouting after spinal cord injury. — PubMed · 2006 · Comparative Study
- Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury. — PubMed · 2006 · Journal Article
- Dural repair reduces connective tissue scar invasion and cystic cavity formation after acute spinal cord laceration injury in adult rats. — PubMed · 2006 · Journal Article
- Minocycline neuroprotects, reduces microgliosis, and inhibits caspase protease expression early after spinal cord injury. — PubMed · 2006 · Journal Article
- Regeneration of the rat spinal cord after thoracic segmentectomy: restoration of the anatomical integrity of the spinal cord. — PubMed · 2006 · Comparative Study
- Antibodies against the NG2 proteoglycan promote the regeneration of sensory axons within the dorsal columns of the spinal cord. — PubMed · 2006 · Comparative Study
- [Effects of cyclin dependent protein kinase inhibitor olomoucine on the microenvironment of axonal regeneration after spinal cord injury: an experiment with rats]. — PubMed · 2006 · Journal Article
- Accumulation of the inhibitory receptor EphA4 may prevent regeneration of corticospinal tract axons following lesion. — PubMed · 2006 · Journal Article
- Decorin promotes plasminogen/plasmin expression within acute spinal cord injuries and by adult microglia in vitro. — PubMed · 2006 · Journal Article
- Progesterone increases the expression of myelin basic protein and the number of cells showing NG2 immunostaining in the lesioned spinal cord. — PubMed · 2006 · Journal Article
- Compressive myelopathy due to intervertebral disk extrusion in a llama (Lama glama). — PubMed · 2006 · Case Reports
- Intraspinal grafting procedures: spinal cord effects induced in the adult rat: a clinical, histopathological, and immunohistochemical study. — PubMed · 2006 · Comparative Study
- Systemic injections of lipopolysaccharide accelerates myelin phagocytosis during Wallerian degeneration in the injured mouse spinal cord. — PubMed · 2006 · Journal Article
- Chondroitinase ABC combined with neural stem/progenitor cell transplantation enhances graft cell migration and outgrowth of growth-associated protein-43-positive fibers after rat spinal cord injury. — PubMed · 2005 · Comparative Study
- Spinal cord diffusion tensor imaging and fiber tracking can identify white matter tract disruption and glial scar orientation following lateral funiculotomy. — PubMed · 2005 · Journal Article
- Suppression of fibrous scarring in spinal cord injury of rat promotes long-distance regeneration of corticospinal tract axons, rescue of primary motoneurons in somatosensory cortex and significant functional recovery. — PubMed · 2005 · Comparative Study
- Homologous transplantation of neural stem cells to the injured spinal cord of mice. — PubMed · 2005 · Comparative Study
- Estrogen attenuated markers of inflammation and decreased lesion volume in acute spinal cord injury in rats. — PubMed · 2005 · Journal Article
- Disruption of the hyaluronan-based extracellular matrix in spinal cord promotes astrocyte proliferation. — PubMed · 2005 · Journal Article
- FK 506 reduces tissue damage and prevents functional deficit after spinal cord injury in the rat. — PubMed · 2005 · Journal Article
- Immune regulatory mechanisms influence early pathology in spinal cord injury and in spontaneous autoimmune encephalomyelitis. — PubMed · 2005 · Comparative Study
- A novel role of lactosylceramide in the regulation of tumor necrosis factor alpha-mediated proliferation of rat primary astrocytes. Implications for astrogliosis following neurotrauma. — PubMed · 2005 · Journal Article
- X-irradiation reduces lesion scarring at the contusion site of adult rat spinal cord. — PubMed · 2005 · Journal Article
- Spinal cord injury induction of lesional expression of profibrotic and angiogenic connective tissue growth factor confined to reactive astrocytes, invading fibroblasts and endothelial cells. — PubMed · 2005 · Journal Article
- Conditioning injury-induced spinal axon regeneration requires signal transducer and activator of transcription 3 activation. — PubMed · 2005 · Comparative Study
- Combining Schwann cell bridges and olfactory-ensheathing glia grafts with chondroitinase promotes locomotor recovery after complete transection of the spinal cord. — PubMed · 2005 · Comparative Study
- Attenuation of acute inflammatory response by atorvastatin after spinal cord injury in rats. — PubMed · 2005 · Journal Article
- Calpain inhibitor inhibits p35-p25-Cdk5 activation, decreases tau hyperphosphorylation, and improves neurological function after spinal cord hemisection in rats. — PubMed · 2005 · Comparative Study
- [Spinal cord regeneration in rats after thoracic segmentectomy: restoration of the anatomical integrity of the spinal cord]. — PubMed · 2005 · English Abstract
- Astrocytosis, microglia activation, oligodendrocyte degeneration, and pyknosis following acute spinal cord injury. — PubMed · 2004 · Journal Article
- Modification of the regenerative response of dorsal column axons by olfactory ensheathing cells or peripheral axotomy in adult rat. — PubMed · 2004 · Journal Article
- Axonal regeneration and lack of astrocytic gliosis in EphA4-deficient mice. — PubMed · 2004 · Journal Article
- K+ channel blockade impairs remyelination in the cuprizone model. — PubMed · 2004 · Journal Article
- Regeneration of adult rat spinal cord is promoted by the soluble KDI domain of gamma1 laminin. — PubMed · 2004 · Comparative Study
- AIT-082 and methylprednisolone singly, but not in combination, enhance functional and histological improvement after acute spinal cord injury in rats. — PubMed · 2004 · Journal Article
- Long-term changes in the molecular composition of the glial scar and progressive increase of serotoninergic fibre sprouting after hemisection of the mouse spinal cord. — PubMed · 2004 · Comparative Study
- The role of Fas-mediated apoptosis after traumatic spinal cord injury. — PubMed · 2004 · Journal Article
- The phosphodiesterase inhibitor rolipram delivered after a spinal cord lesion promotes axonal regeneration and functional recovery. — PubMed · 2004 · Journal Article
- Dural closure, cord approximation, and clot removal: enhancement of tissue sparing in a novel laceration spinal cord injury model. — PubMed · 2004 · Journal Article
- Electrical preconditioning attenuates progressive necrosis and cavitation following spinal cord injury. — PubMed · 2004 · Journal Article
- Traumatic injury-induced midkine expression in the adult rat spinal cord during the early stage. — PubMed · 2004 · Journal Article
- Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury. — PubMed · 2004 · Journal Article
- Decorin suppresses neurocan, brevican, phosphacan and NG2 expression and promotes axon growth across adult rat spinal cord injuries. — PubMed · 2004 · Journal Article
- PKC mediates inhibitory effects of myelin and chondroitin sulfate proteoglycans on axonal regeneration. — PubMed · 2004 · Journal Article
- A novel DNA enzyme reduces glycosaminoglycan chains in the glial scar and allows microtransplanted dorsal root ganglia axons to regenerate beyond lesions in the spinal cord. — PubMed · 2004 · Journal Article
- Prevention of gliotic scar formation by NeuroGel allows partial endogenous repair of transected cat spinal cord. — PubMed · 2004 · Journal Article
- Differential gene expression after complete spinal cord transection in adult rats: an analysis focused on a subchronic post-injury stage. — PubMed · 2004 · Journal Article
- Comparison of iNOS inhibition by antisense and pharmacological inhibitors after spinal cord injury. — PubMed · 2003 · Comparative Study
- Blood-spinal cord barrier after spinal cord injury: relation to revascularization and wound healing. — PubMed · 2003 · Journal Article
- Spontaneous regeneration of the corticospinal tract after transection in young rats: collagen type IV deposition and astrocytic scar in the lesion site are not the cause but the effect of failure of regeneration. — PubMed · 2003 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-09-29 Collection window: 2026-09-16 – 2026-09-29 | matched in this collection walk 0 · accumulated records across collection walks 4 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 851162 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 7 · accumulated records across collection walks 1725 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("glial scar" OR "astrogliosis" OR "fibrotic scar") - Crossref
spinal cord injury glial scar astrogliosis - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Gliosis"[MeSH Terms] OR "Cicatrix"[MeSH Terms] OR "glial scar"[Title/Abstract] OR "astrogliosis"[Title/Abstract] OR "fibrotic scar"[Title/Abstract])