A subject this map covers
Glial scar and its remodelling
What belongs here
The tissue that forms around the lesion, and attempts to change it — soften, remodel or use it.
What does not belong here, however close it looks
Skin or soft-tissue scarring after surgery does not belong here.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 478 records · 1963–2026
- Indexed as work in animals: 879 records · 1969–2026
- Indexed as laboratory work: 59 records · 1992–2026
- The source has not said who or what was studied: 294 records · 1983–2026
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1710 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Differential temporal expression of matrix metalloproteinases after spinal cord injury: relationship to revascularization and wound healing. — PubMed · 2003 · Journal Article
- Activation of embryonic intermediate filaments contributes to glial scar formation after spinal cord injury in rats. — PubMed · 2003 · Journal Article
- Significance of fixation of the vertebral column for spinal cord injury experiments. — PubMed · 2003 · Journal Article
- TIGR is upregulated in the chronic glial scar in response to central nervous system injury and inhibits neurite outgrowth. — PubMed · 2003 · Journal Article
- Endothelin receptor expression in the normal and injured spinal cord: potential involvement in injury-induced ischemia and gliosis. — PubMed · 2003 · Journal Article
- The Rho/ROCK pathway mediates neurite growth-inhibitory activity associated with the chondroitin sulfate proteoglycans of the CNS glial scar. — PubMed · 2003 · Journal Article
- Changes in distribution, cell associations, and protein expression levels of NG2, neurocan, phosphacan, brevican, versican V2, and tenascin-C during acute to chronic maturation of spinal cord scar tissue. — PubMed · 2003 · Journal Article
- Physical size does not determine the unique histopathological response seen in the injured mouse spinal cord. — PubMed · 2003 · Comparative Study
- [Repair of the mammalian central nervous system: the "spinal cord" model]. — PubMed · 2003 · English Abstract
- Basis of progesterone protection in spinal cord neurodegeneration. — PubMed · 2002 · Journal Article
- Reaxotomy of chronically injured rubrospinal neurons results in only modest cell loss. — PubMed · 2002 · Journal Article
- The neuropathological and behavioral consequences of intraspinal microglial/macrophage activation. — PubMed · 2002 · Journal Article
- Expression of TGFbeta2 but not TGFbeta1 correlates with the deposition of scar tissue in the lesioned spinal cord. — PubMed · 2002 · Journal Article
- Upregulation of Kv 1.4 protein and gene expression after chronic spinal cord injury. — PubMed · 2002 · Journal Article
- Development and characterization of a novel, graded model of clip compressive spinal cord injury in the mouse: Part 1. Clip design, behavioral outcomes, and histopathology. — PubMed · 2002 · Journal Article
- Locomotor performance of the rat after neonatal repairing of spinal cord injuries: quantitative assessment and electromyographic study. — PubMed · 2002 · Journal Article
- Recovery from spinal cord injury: a new transection model in the C57Bl/6 mouse. — PubMed · 2002 · Journal Article
- Expression of neuregulin and ErbB3 and ErbB4 after a traumatic lesion in the ventral funiculus of the spinal cord and in the intact primary olfactory system. — PubMed · 2002 · Comparative Study
- Spinal cord regeneration: from gene to transplants. — PubMed · 2001 · Journal Article
- Intermediate filaments regulate astrocyte motility. — PubMed · 2001 · Journal Article
- Inhibition of calpain-mediated apoptosis by E-64 d-reduced immediate early gene (IEG) expression and reactive astrogliosis in the lesion and penumbra following spinal cord injury in rats. — PubMed · 2001 · Journal Article
- A reliable method to reduce collagen scar formation in the lesioned rat spinal cord. — PubMed · 2001 · Journal Article
- Chronic intrathecal infusions after spinal cord injury cause scarring and compression. — PubMed · 2001 · Journal Article
- Support of axonal regrowth by endogenous mechanisms following spinal cord injury in adult rats. — PubMed · 2001 · Journal Article
- Effects of ensheathing cells transplanted into photochemically damaged spinal cord. — PubMed · 2001 · Journal Article
- White matter preservation after spinal cord injury in ICAM-1/P-selectin-deficient mice. — PubMed · 2001 · Journal Article
- Chemokine antagonist infusion promotes axonal sparing after spinal cord contusion injury in rat. — PubMed · 2001 · Journal Article
- MMP-related gelatinase activity is strongly induced in scar tissue of injured adult spinal cord and forms pathways for ingrowing neurites. — PubMed · 2001 · Journal Article
- Preservation and detection of lesion-induced collagenous scar in the CNS depend on the method of tissue processing. — PubMed · 2001 · Journal Article
- Improved recovery after spinal cord injury in neuronal nitric oxide synthase-deficient mice but not in TNF-alpha-deficient mice. — PubMed · 2001 · Journal Article
- The effects of tubulation on healing and scar formation after transection of the adult rat spinal cord. — PubMed · 2001 · Journal Article
- Differential expression of tenascin-C, tenascin-R, tenascin/J1, and tenascin-X in spinal cord scar tissue and in the olfactory system. — PubMed · 2000 · Journal Article
- Efficacy of a new neuroprotective agent, gacyclidine, in a model of rat spinal cord injury. — PubMed · 2000 · Comparative Study
- Induction of VEGF and VEGF receptors in the spinal cord after mechanical spinal injury and prostaglandin administration. — PubMed · 2000 · Journal Article
- Basic fibroblast growth factor (bFGF) enhances functional recovery following severe spinal cord injury to the rat. — PubMed · 2000 · Journal Article
- The barrier effect of laminae: laminotomy versus laminectomy. — PubMed · 2000 · Journal Article
- Cytokine chemokine expression in contused rat spinal cord. — PubMed · 2000 · Journal Article
- Leukaemia inhibitory factor is required for normal inflammatory responses to injury in the peripheral and central nervous systems in vivo and is chemotactic for macrophages in vitro. — PubMed · 2000 · Journal Article
- Chemokine antagonist infusion attenuates cellular infiltration following spinal cord contusion injury in rat. — PubMed · 2000 · Journal Article
- Effects of spinal cord X-irradiation on the recovery of paraplegic rats. — PubMed · 2000 · Journal Article
- Elimination of basal lamina and the collagen "scar" after spinal cord injury fails to augment corticospinal tract regeneration. — PubMed · 1999 · Journal Article
- Basic fibroblast growth factor (bFGF) enhances tissue sparing and functional recovery following moderate spinal cord injury. — PubMed · 1999 · Journal Article
- Carbon filaments direct the growth of postlesional plastic axons after spinal cord injury. — PubMed · 1999 · Journal Article
- Abnormal reaction to central nervous system injury in mice lacking glial fibrillary acidic protein and vimentin. — PubMed · 1999 · Journal Article
- Calcium influx and activation of calpain I mediate acute reactive gliosis in injured spinal cord. — PubMed · 1999 · Journal Article
- Simple and reproducible model of rat spinal cord injury induced by a controlled cortical impact device. — PubMed · 1999 · Journal Article
- Expression of the gene encoding the chemorepellent semaphorin III is induced in the fibroblast component of neural scar tissue formed following injuries of adult but not neonatal CNS. — PubMed · 1999 · Journal Article
- CM101-mediated recovery of walking ability in adult mice paralyzed by spinal cord injury. — PubMed · 1998 · Journal Article
- Nerve growth factor induces process formation in meningeal cells: implications for scar formation in the injured CNS. — PubMed · 1998 · Journal Article
- Cytokine mRNA profiles in contused spinal cord and axotomized facial nucleus suggest a beneficial role for inflammation and gliosis. — PubMed · 1998 · Journal Article
- Long-distance axonal regeneration in the transected adult rat spinal cord is promoted by olfactory ensheathing glia transplants. — PubMed · 1998 · Journal Article
- Spontaneous regeneration of the pyramidal tract after transection in young rats. — PubMed · 1998 · Comparative Study
- Connexin43 and astrocytic gap junctions in the rat spinal cord after acute compression injury. — PubMed · 1997 · Comparative Study
- Brain-derived neurotrophic factor reduces necrotic zone and supports neuronal survival after spinal cord hemisection in adult rats. — PubMed · 1996 · Journal Article
- Improvement of host-graft adhesion by enzymatic manipulation of the subacute spinal cord contusion area in the rat. — PubMed · 1996 · Journal Article
- Effects of Schwann cell transplantation in a contusion model of rat spinal cord injury. — PubMed · 1996 · Journal Article
- Effects of exogenous transforming growth factor-beta 1 on spinal cord injury in rats. — PubMed · 1996 · Journal Article
- Morphological changes in sympathetic preganglionic neurons after spinal cord injury in rats. — PubMed · 1996 · Journal Article
- Application of polyvinyl alcohol hydrogel membrane as anti-adhesive interposition after spinal surgery. — PubMed · 1995 · Comparative Study
- Oxysterol (7 beta-hydroxycholesteryl-3-oleate) promotes serotonergic reinnervation in the lesioned rat spinal cord by reducing glial reaction. — PubMed · 1995 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-09-29 Collection window: 2026-09-16 – 2026-09-29 | matched in this collection walk 0 · accumulated records across collection walks 4 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 851162 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 7 · accumulated records across collection walks 1725 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("glial scar" OR "astrogliosis" OR "fibrotic scar") - Crossref
spinal cord injury glial scar astrogliosis - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Gliosis"[MeSH Terms] OR "Cicatrix"[MeSH Terms] OR "glial scar"[Title/Abstract] OR "astrogliosis"[Title/Abstract] OR "fibrotic scar"[Title/Abstract])