A subject this map covers
Glial scar and its remodelling
What belongs here
The tissue that forms around the lesion, and attempts to change it — soften, remodel or use it.
What does not belong here, however close it looks
Skin or soft-tissue scarring after surgery does not belong here.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 478 records · 1963–2026
- Indexed as work in animals: 879 records · 1969–2026
- Indexed as laboratory work: 59 records · 1992–2026
- The source has not said who or what was studied: 294 records · 1983–2026
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1710 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as laboratory work
- Neuroectodermal stem cells: A remyelinating potential in acute compressed spinal cord injury in rat model. — PubMed · 2018 · Journal Article
- Cetuximab and Taxol co-modified collagen scaffolds show combination effects for the repair of acute spinal cord injury. — PubMed · 2018 · Journal Article
- Effect of hyaluronic acid hydrogels containing astrocyte-derived extracellular matrix and/or V2a interneurons on histologic outcomes following spinal cord injury. — PubMed · 2018 · Journal Article
- The neuroprotective effect of rat adipose tissue-derived mesenchymal stem cell-conditioned medium on cortical neurons using an in vitro model of SCI inflammation. — PubMed · 2018 · Journal Article
- RNAi-mediated ephrin-B2 silencing attenuates astroglial-fibrotic scar formation and improves spinal cord axon growth. — PubMed · 2017 · Journal Article
- Regulation of RhoA by STAT3 coordinates glial scar formation. — PubMed · 2017 · Journal Article
- Non-viral xylosyltransferase-1 siRNA delivery as an effective alternative to chondroitinase in an in vitro model of reactive astrocytes. — PubMed · 2016 · Journal Article
- Pharmacological Suppression of CNS Scarring by Deferoxamine Reduces Lesion Volume and Increases Regeneration in an In Vitro Model for Astroglial-Fibrotic Scarring and in Rat Spinal Cord Injury In Vivo. — PubMed · 2015 · Journal Article
- Olfactory ensheathing cell-neurite alignment enhances neurite outgrowth in scar-like cultures. — PubMed · 2015 · Journal Article
- Spinal motor neurite outgrowth over glial scar inhibitors is enhanced by coculture with bone marrow stromal cells. — PubMed · 2014 · Journal Article
- Abrogation of β-catenin signaling in oligodendrocyte precursor cells reduces glial scarring and promotes axon regeneration after CNS injury. — PubMed · 2014 · Journal Article
- Improved axonal regeneration after spinal cord injury in mice with conditional deletion of ephrin B2 under the GFAP promoter. — PubMed · 2013 · Journal Article
- New serum-derived albumin scaffold seeded with adipose-derived stem cells and olfactory ensheathing cells used to treat spinal cord injured rats. — PubMed · 2013 · Journal Article
- BD PuraMatrix peptide hydrogel as a culture system for human fetal Schwann cells in spinal cord regeneration. — PubMed · 2012 · Evaluation Study
- [Effects of bone marrow mesenchymal stem cells with acellular muscle bioscaffolds on repair of acute hemi-transection spinal cord injury in rats]. — PubMed · 2012 · Journal Article
- The roles of neuronal and glial precursors in overcoming chondroitin sulfate proteoglycan inhibition. — PubMed · 2012 · Comparative Study
- Neuronal glycosylation differentials in normal, injured and chondroitinase-treated environments. — PubMed · 2012 · Journal Article
- Combination of activated Schwann cells with bone mesenchymal stem cells: the best cell strategy for repair after spinal cord injury in rats. — PubMed · 2011 · Journal Article
- Single-walled carbon nanotubes chemically functionalized with polyethylene glycol promote tissue repair in a rat model of spinal cord injury. — PubMed · 2011 · Journal Article
- Curcumin attenuates the expression and secretion of RANTES after spinal cord injury in vivo and lipopolysaccharide-induced astrocyte reactivation in vitro. — PubMed · 2011 · Journal Article
- GDNF modifies reactive astrogliosis allowing robust axonal regeneration through Schwann cell-seeded guidance channels after spinal cord injury. — PubMed · 2011 · Journal Article
- Interaction of olfactory ensheathing cells with other cell types in vitro and after transplantation: glial scars and inflammation. — PubMed · 2011 · Journal Article
- Lentiviral vector-mediated knockdown of the NG2 [corrected] proteoglycan or expression of neurotrophin-3 promotes neurite outgrowth in a cell culture model of the glial scar. — PubMed · 2010 · Journal Article
- Alignment of astrocytes increases neuronal growth in three-dimensional collagen gels and is maintained following plastic compression to form a spinal cord repair conduit. — PubMed · 2010 · Journal Article
- Neurite outgrowth of neural progenitors in presence of inhibitory proteoglycans. — PubMed · 2010 · Journal Article
- Synergistic effect of neural stem cells and olfactory ensheathing cells on repair of adult rat spinal cord injury. — PubMed · 2010 · Journal Article
- Tumor necrosis factor alpha enhances glutamatergic transmission onto spinal motoneurons. — PubMed · 2010 · Journal Article
- Transplantation of human marrow stromal cells and mono-nuclear bone marrow cells into the injured spinal cord: a comparative study. — PubMed · 2009 · Comparative Study
- Human umbilical cord blood stem cells upregulate matrix metalloproteinase-2 in rats after spinal cord injury. — PubMed · 2009 · Journal Article
- Chronic erythropoietin-mediated effects on the expression of astrocyte markers in a rat model of contusive spinal cord injury. — PubMed · 2008 · Journal Article
- Studies on the development and behavior of the dystrophic growth cone, the hallmark of regeneration failure, in an in vitro model of the glial scar and after spinal cord injury. — PubMed · 2004 · Journal Article
- Blockade of interleukin-6 receptor suppresses reactive astrogliosis and ameliorates functional recovery in experimental spinal cord injury. — PubMed · 2004 · Comparative Study
- Glial scar and axonal regeneration in the CNS: lessons from GFAP and vimentin transgenic mice. — PubMed · 2004 · Comparative Study
- Molecular approaches to spinal cord repair. — PubMed · 2003 · Journal Article
- Increase in spinal canal area after inverse laminoplasty: an anatomical study. — PubMed · 2000 · Comparative Study
- CNS glial scar tissue: a source of molecules which inhibit central neurite outgrowth. — PubMed · 1992 · Journal Article
The source has not said who or what was studied
- Dual strategies for neural injury repair: Targeted modulation of reactive astrocytes and functional astrocyte transplantation. — PubMed · 2026 · Journal Article
- Regional heterogeneity in fibrotic scar formation and early functional recovery in cervical, thoracic, and lumbar spinal cord injuries. — PubMed · 2026 · Journal Article
- A Gata4-Loxl2 axis controls ECM remodeling to enable scar-free spinal cord regeneration in zebrafish. — PubMed · 2026 · Journal Article
- Spatiotemporal disarray of inflammatory microenvironment following spinal cord injury. — PubMed · 2026 · Journal Article
- Therapeutic potential of astrocyte transdifferentiated neurons. — PubMed · 2026 · Journal Article
- Hyaluronic acid-alginate hydrazone crosslinked hydrogels support the generation and maturation of V2a interneurons. — PubMed · 2026 · Journal Article
- Ultrasound-responsive nanotherapy promotes axonal regeneration after SCI via reactivating CREB/miR-129-5p signaling. — PubMed · 2026 · Journal Article
- Activated olfactory ensheathing cells suppress astrocyte reactivity and CSPGs expression through IL-10 signaling in an in vitro scratch-injury model of glial scarring. — PubMed · 2026 · Journal Article
- A pH-responsive and self-healing CEC/PEG-(CHO)(2) hydrogel for controlled neuropeptide S delivery and endogenous neural repair after spinal cord injury. — PubMed · 2026 · Journal Article
- TRANsCre-DIONE transdifferentiates scar-forming reactive astrocytes into functional motor neurons. — PubMed · 2026 · Journal Article
- Rictor/mTORC2 signaling pathway protects endogenous neural stem cells to promote recovery after spinal cord injury. — PubMed · 2026 · Journal Article
- Treatment with Neuronal-Induced Human Mesenchymal Stem Cells Improves Functional Recovery of Acute Spinal Cord Injury through Attenuating Astrogliosis and Neurotoxic Astrocyte Activation. — PubMed · 2026 · Journal Article
- Curcumin-activated olfactory ensheathing cells attenuate astroglial scar to facilitate nerve repair via the IL-10/NF-κB axis after spinal cord injury. — PubMed · 2026 · Journal Article
- NAD(+) supplementation and PARP inhibition following spinal cord injury in mice: Hurdles and considerations for therapeutic use. — PubMed · 2026 · Journal Article
- Photobiomodulation‑Engineered Extracellular Vesicles Enhance Neural Differentiation via UFL1‑Mediated UFMylation in Spinal Cord Injury. — PubMed · 2026 · Journal Article
- ZO-1-dependent fibrotic scar border formation impedes axon regeneration after spinal cord injury. — PubMed · 2026 · Journal Article
- Sonic Hedgehog Signaling Promotes Survival and Lineage Specific Differentiation of Transplanted Neural Precursor Cells and Improves Motor Recovery After Thoracic Spinal Cord Injury in Rats. — PubMed · 2026 · Journal Article
- Research Evolution and Frontiers in Glial Scar and Spinal Cord Injury Research: A Bibliometric Perspective — Crossref · 2026 · journal-article
- Extracellular matrix remodelling in degenerative cervical myelopathy. — PubMed · 2026 · Journal Article
- Mechanical Remodeling and Mechanosensing after Spinal Cord Injury: From Molecular to Translational Approaches. — PubMed · 2026 · Journal Article
- PBAE nanoparticle-mediated delivery of ASCL1 and NGN2 genes for astroglia-to-neuron reprogramming to remodel glial scar for spinal cord injury repair. — PubMed · 2026 · Journal Article
- Smart-responsive electrospun scaffolds (SRES) for neural repair: Recent advances and future prospects. — PubMed · 2026 · Journal Article
- An integrated hydrogel-V3 interneuron therapy promotes functional repair of spinal cord injury via neural circuit reconstruction and microenvironment remodeling. — PubMed · 2026 · Journal Article
- Screening the optimal rTSMS frequency to orchestrate immune-fibrotic remodeling for adult spinal cord repair. — PubMed · 2026 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-09-29 Collection window: 2026-09-16 – 2026-09-29 | matched in this collection walk 0 · accumulated records across collection walks 4 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 851162 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 7 · accumulated records across collection walks 1725 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("glial scar" OR "astrogliosis" OR "fibrotic scar") - Crossref
spinal cord injury glial scar astrogliosis - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Gliosis"[MeSH Terms] OR "Cicatrix"[MeSH Terms] OR "glial scar"[Title/Abstract] OR "astrogliosis"[Title/Abstract] OR "fibrotic scar"[Title/Abstract])