A subject this map covers
Glial scar and its remodelling
What belongs here
The tissue that forms around the lesion, and attempts to change it — soften, remodel or use it.
What does not belong here, however close it looks
Skin or soft-tissue scarring after surgery does not belong here.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 478 records · 1963–2026
- Indexed as work in animals: 879 records · 1969–2026
- Indexed as laboratory work: 59 records · 1992–2026
- The source has not said who or what was studied: 294 records · 1983–2026
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1710 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
The source has not said who or what was studied
- Plasticity, injury-induced reprogramming, and translational applications of Schwann cells in neural regeneration. — PubMed · 2026 · Journal Article
- Hyaluronic Acid-Alginate Hydrazone Crosslinked Hydrogels Support the Generation and Maturation of V2a Interneurons. — PubMed · 2026 · Journal Article
- Exercise training promotes nerve cell repair and regeneration after spinal cord injury. — PubMed · 2026 · Journal Article
- NG2 Glia and Cellular Crosstalk in Health and Disease: Focus on Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Regulatory role of neuronal guidance proteins in spinal cord injury. — PubMed · 2026 · Journal Article
- Targeting the glial-fibrotic scar microenvironment after spinal cord injury: From integrated protection to systematic regulation of regenerative balance. — PubMed · 2026 · Journal Article
- Inhibition of Lin-11, Isl-1, and Mec‑3 Kinase (LIMK) Activity Attenuates Astrogliosis and Vascular Remodeling in an Experimental Model of Cuprizone-Induced Demyelination in Mice. — PubMed · 2026 · Journal Article
- Advances in Hydrogel Tissue Engineering for Spinal Cord Injury Repair. — PubMed · 2026 · Journal Article
- Effect of mitochondrial dysfunction on scar formation after spinal cord injury. — PubMed · 2026 · Journal Article
- A sequential multimodal framework for spinal cord regeneration. — PubMed · 2026 · Journal Article
- Exosomes as regenerative therapeutics for spinal cord injury: mechanisms and clinical prospects. — PubMed · 2026 · Journal Article
- ROS-responsive hydrogels functionalized with Cu/Zn MOF targeting oxidative stress mitigation and inflammation modulation to promote spinal cord injury repair. — PubMed · 2026 · Journal Article
- The role of gene therapy in neural injury repair. — PubMed · 2026 · Journal Article
- Targeting glial scar formation for spinal cord injury: mechanisms, strategies, and research progress review — Crossref · 2026 · journal-article
- Establishing an experimental model approach to thermal-induced spinal cord injury in mice. — PubMed · 2026 · Journal Article
- Targeting the Jun-Irf8-CD36 axis attenuates fibrotic scar formation and promotes functional recovery after spinal cord injury. — PubMed · 2026 · Journal Article
- Microglial lipid metabolism and epigenetic regulation: Emerging targets for spinal cord injury therapy. — PubMed · 2026 · Journal Article
- Targeting PTGS2 Attenuates Neuroinflammation and Glial Scar Formation: The Neuroprotective Mechanism of Luteolin in Spinal Cord Injury — Crossref · 2026 · posted-content
- TGF-β-induced fibrotic scar formation limits recovery of spinal cord injury. — PubMed · 2026 · Journal Article
- Treatment of spinal cord injury, by restoration of neuronal networks using a combination of surgery and KCL-286, an orally available retinoic acid receptor β drug. — PubMed · 2026 · Journal Article
- Peptide Hydrogel Incorporating Hydroxyapatite and Neural Stem Cells to Facilitate Spinal Cord Injury Regeneration. — PubMed · 2026 · Journal Article
- Injury and therapy in a human spinal cord organoid. — PubMed · 2026 · Journal Article
- Profibrotic macrophage-derived CXCL4 promotes pericyte-to-myofibroblast transition after spinal cord injury. — PubMed · 2026 · Journal Article
- Immunohistochemical Evaluation of Spinal Cord Injuries Treated with Amniotic Membrane. — PubMed · 2026 · Journal Article
- Nano-primed reprogrammed neurons suppress the glial scar and facilitate axonal regeneration after spinal cord injury — Crossref · 2026 · journal-article
- Insights into Astrogliosis, Inflammation Processes, and Emerging Treatments by Exosome Therapy and Low-Level Laser Therapy for Spinal Cord Injury: A Systematic Review. — PubMed · 2025 · Journal Article
- Comparative study of treadmill and swimming exercises on spinal regeneration and reactive astrocytes in the brain after spinal cord injury. — PubMed · 2025 · Journal Article
- Hydrogel-Based Biomaterials in Spinal Repair: Evaluating Mechanisms for IVDD, SCI, and Dural Regeneration. — PubMed · 2025 · Journal Article
- Nerve root magnetic stimulation regulates the synaptic plasticity of injured spinal cord by ascending sensory pathway. — PubMed · 2025 · Journal Article
- Sudden onset Brown-Sequard-like symptoms due to fibrotic scar tissue formation around spinal cord stimulator electrode with associated spinal cord compression. — PubMed · 2025 · Case Reports
- Early intervention with extracellular vesicles derived from human umbilical cord mesenchymal stem cells enhances survival and functional recovery after spinal cord injury in rats. — PubMed · 2025 · Journal Article
- Chondroitinase ABC in Neural Regeneration: Advances in CNS and Peripheral Nerve Repair. — PubMed · 2025 · Journal Article
- Electroacupuncture at Huatuo-Jiaji acupoints combined with conductive hydrogel synergistically improves bladder and motor functions after spinal cord injury. — PubMed · 2025 · Journal Article
- Exosomal miR-146a-3p modulates neural stem cell fate through UCHL1 downregulation in spinal cord injury: implications for neuroregeneration. — PubMed · 2025 · Journal Article
- An injectable curcumin-loaded hydrogel for neuroprotective treatment promote nerve tissue repair in rat severe spinal cord injury. — PubMed · 2025 · Journal Article
- The Role of the Wnt/β-Catenin Signaling Pathway in the Pathogenesis and Treatment of Spinal Cord Injury: A Review of the Latest Experimental Data. — PubMed · 2025 · Journal Article
- Injectable ion-coordinated double-network conductive hydrogel for spinal cord injury repair. — PubMed · 2025 · Journal Article
- Therapeutic Potential of Low-Level Laser Therapy in Controlling Inflammation and Damage-Associated Molecular Pattern Regulation in Spinal Cord Injury: A Systematic Review. — PubMed · 2025 · Journal Article
- LncRNA MIR155HG suppresses cell apoptosis by activating autophagy via miR-7036b-3p/GPNMB axis and AMPK/mTOR signaling in spinal cord injury. — PubMed · 2025 · Journal Article
- Biological engineering approaches for modulating the pathological microenvironment and promoting axonal regeneration after spinal cord injury. — PubMed · 2025 · Journal Article
- Preclinical efficacy and safety assessments of Adult human neural stem cells (AhNSCs) for spinal cord injury. — PubMed · 2025 · Journal Article
- Chondroitinase ABC combined with Schwann cell transplantation enhances restoration of neural connection and functional recovery following acute and chronic spinal cord injury. — PubMed · 2025 · Journal Article
- Effect of microglial Pd1 on glial scar formation after spinal cord injury in mice — Crossref · 2025 · journal-article
- Dual-Responsive Multi-Functional Silica Nanoparticles With Repaired Mitochondrial Functions for Efficient Alleviation of Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Olfactory ensheathing cells from adult female rats are hybrid glia that promote neural repair. — PubMed · 2025 · Journal Article
- Corrigendum: Icariin promotes functional recovery in rats after spinal cord injury by inhibiting YAP and regulating PPM1B ubiquitination to inhibiting the activation of reactive astrocytes. — PubMed · 2024 · Published Erratum
- The Role of Inflammatory Cascade and Reactive Astrogliosis in Glial Scar Formation Post-spinal Cord Injury — Crossref · 2024 · journal-article
- Temperature-sensitive sodium beta-glycerophosphate/chitosan hydrogel loaded with all-trans retinoic acid regulates Pin1 to inhibit the formation of spinal cord injury-induced rat glial scar. — PubMed · 2024 · Journal Article
- Galectin-3 inhibition reduces fibrotic scarring and promotes functional recovery after spinal cord injury in mice. — PubMed · 2024 · Journal Article
- Icariin promotes functional recovery in rats after spinal cord injury by inhibiting YAP and regulating PPM1B ubiquitination to inhibiting the activation of reactive astrocytes. — PubMed · 2024 · Journal Article
- Inosine Improves Functional Recovery and Cell Morphology Following Compressive Spinal Cord Injury in Mice. — PubMed · 2024 · Journal Article
- Modulation of the LIMK Pathway by Myricetin: A Protective Strategy Against Neurological Impairments in Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Targeting transcription factor pu.1 for improving neurologic outcomes after spinal cord injury. — PubMed · 2024 · Journal Article
- Repair of spinal cord injury by bone marrow mesenchymal stem cell-derived exosomes: a systematic review and meta-analysis based on rat models. — PubMed · 2024 · Journal Article
- Editorial: Restoring neural circuits after spinal cord injury. — PubMed · 2024 · Editorial
- The secondary injury cascade after spinal cord injury: an analysis of local cytokine/chemokine regulation. — PubMed · 2024 · Journal Article
- Functional biomaterials for modulating the dysfunctional pathological microenvironment of spinal cord injury. — PubMed · 2024 · Journal Article
- Astrocytes, reactive astrogliosis, and glial scar formation in traumatic brain injury — Crossref · 2024 · journal-article
- Salidroside promotes the repair of spinal cord injury by inhibiting astrocyte polarization, promoting neural stem cell proliferation and neuronal differentiation. — PubMed · 2024 · Journal Article
- Collagen I is a critical organizer of scarring and CNS regeneration failure. — PubMed · 2024 · Preprint
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-09-29 Collection window: 2026-09-16 – 2026-09-29 | matched in this collection walk 0 · accumulated records across collection walks 4 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 851162 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 7 · accumulated records across collection walks 1725 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("glial scar" OR "astrogliosis" OR "fibrotic scar") - Crossref
spinal cord injury glial scar astrogliosis - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Gliosis"[MeSH Terms] OR "Cicatrix"[MeSH Terms] OR "glial scar"[Title/Abstract] OR "astrogliosis"[Title/Abstract] OR "fibrotic scar"[Title/Abstract])