A subject this map covers
Glial scar and its remodelling
What belongs here
The tissue that forms around the lesion, and attempts to change it — soften, remodel or use it.
What does not belong here, however close it looks
Skin or soft-tissue scarring after surgery does not belong here.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 478 records · 1963–2026
- Indexed as work in animals: 879 records · 1969–2026
- Indexed as laboratory work: 59 records · 1992–2026
- The source has not said who or what was studied: 294 records · 1983–2026
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
1710 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
The source has not said who or what was studied
- The role of small extracellular vesicles and microRNA as their cargo in the spinal cord injury pathophysiology and therapy. — PubMed · 2024 · Journal Article
- Non-resolving neuroinflammation regulates axon regeneration in chronic spinal cord injury. — PubMed · 2024 · Preprint
- Argatroban promotes recovery of spinal cord injury by inhibiting the PAR1/JAK2/STAT3 signaling pathway. — PubMed · 2024 · Journal Article
- Inhibition of CD44 suppresses the formation of fibrotic scar after spinal cord injury via the JAK2/STAT3 signaling pathway. — PubMed · 2024 · Journal Article
- The Role of Interleukin-10 in the Pathogenesis and Treatment of a Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Author Correction: Low oral dose of 4-methylumbelliferone reduces glial scar but is insufficient to induce functional recovery after spinal cord injury. — PubMed · 2024 · Published Erratum
- Design and synthesis of nano-biomaterials based on graphene and local delivery of cerebrolysin into the injured spinal cord of mice, promising neural restoration. — PubMed · 2024 · Journal Article
- Intravenous administration exosomes derived from human amniotic mesenchymal stem cells improves neurological recovery after acute traumatic spinal cord injury in rats. — PubMed · 2024 · Journal Article
- Photobiomodulation inhibits the expression of chondroitin sulfate proteoglycans after spinal cord injury via the Sox9 pathway. — PubMed · 2024 · Journal Article
- Mesenchymal Stem Cells Combined With Electroacupuncture Treatment Regulate the Subpopulation of Macrophages and Astrocytes to Facilitate Axonal Regeneration in Transected Spinal Cord. — PubMed · 2023 · Journal Article
- Transcriptomic analysis of spinal cord regeneration after injury in Cynops orientalis. — PubMed · 2023 · Journal Article
- Ferroptosis inhibition protects vascular endothelial cells and maintains integrity of the blood-spinal cord barrier after spinal cord injury. — PubMed · 2023 · Journal Article
- Human Mesenchymal Stem Cell Transplantation Improved Functional Outcomes Following Spinal Cord Injury Concomitantly with Neuroblast Regeneration. — PubMed · 2023 · Journal Article
- Function of GSK‑3 signaling in spinal cord injury (Review). — PubMed · 2023 · Journal Article
- Lentivirus-mediated knockdown of Ski inhibits glial scar formation and promotes axonal regeneration and functional recovery after spinal cord injury in rats — Crossref · 2023 · posted-content
- The role of purinergic receptors in neural repair and regeneration after spinal cord injury. — PubMed · 2023 · Journal Article
- An injectable, self-healing, electroconductive hydrogel loaded with neural stem cells and donepezil for enhancing local therapy effect of spinal cord injury. — PubMed · 2023 · Journal Article
- Understanding the Role of the Glial Scar through the Depletion of Glial Cells after Spinal Cord Injury — Crossref · 2023 · journal-article
- Molecular and cellular changes in the post-traumatic spinal cord remodeling after autoinfusion of a genetically-enriched leucoconcentrate in a mini-pig model. — PubMed · 2023 · Journal Article
- Inhibition of miR-221-3p promotes axonal regeneration and repair of primary sensory neurons via regulating p27 expression. — PubMed · 2023 · Journal Article
- Thermosensitive hydrogel-based GPR124 delivery strategy for rebuilding blood-spinal cord barrier. — PubMed · 2023 · Journal Article
- Microglial depletion impairs glial scar formation and aggravates inflammation partly by inhibiting STAT3 phosphorylation in astrocytes after spinal cord injury. — PubMed · 2023 · Journal Article
- Cell transplantation therapies for spinal cord injury focusing on bone marrow mesenchymal stem cells: Advances and challenges. — PubMed · 2023 · Journal Article
- Understanding the Role of the Glial Scar through the Depletion of Glial Cells after Spinal Cord Injury — Crossref · 2023 · posted-content
- Tackling the glial scar in spinal cord regeneration: new discoveries and future directions. — PubMed · 2023 · Journal Article
- Effects of a neurokinin-1 receptor antagonist in the acute phase after thoracic spinal cord injury in a rat model. — PubMed · 2023 · Journal Article
- Assessment of hindlimb motor recovery after severe thoracic spinal cord injury in rats: classification of CatWalk XT® gait analysis parameters. — PubMed · 2023 · Journal Article
- Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway. — PubMed · 2023 · Journal Article
- Click chemistry extracellular vesicle/peptide/chemokine nanocarriers for treating central nervous system injuries. — PubMed · 2023 · Journal Article
- Vimentin as a potential target for diverse nervous system diseases. — PubMed · 2023 · Journal Article
- Microneurotrophin BNN27 Reduces Astrogliosis and Increases Density of Neurons and Implanted Neural Stem Cell-Derived Cells after Spinal Cord Injury. — PubMed · 2023 · Journal Article
- The Role of Human Neural Stem Cell Secretomes on the Repair of Spinal Cord Injury Post-laminectomy in Rattus norvegicus Through the Analysis of Basso-Beattie-Bresnahan Score Locomotors, Interleukin-10, Matrix Metalloproteinase 9, and Transforming Growth Factor-β. — PubMed · 2023 · Journal Article
- Current Advancements in Spinal Cord Injury Research—Glial Scar Formation and Neural Regeneration — Crossref · 2023 · journal-article
- Neuroprotective role of Noggin in spinal cord injury. — PubMed · 2023 · Journal Article
- Three-dimensional printing of microfiber- reinforced hydrogel loaded with oxymatrine for treating spinal cord injury. — PubMed · 2023 · Journal Article
- The Role of Green Tea Catechin Epigallocatechin Gallate (EGCG) and Mammalian Target of Rapamycin (mTOR) Inhibitor PP242 (Torkinib) in the Treatment of Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Knockdown of polypyrimidine tract binding protein facilitates motor function recovery after spinal cord injury. — PubMed · 2023 · Journal Article
- Research progress of hydrogels as delivery systems and scaffolds in the treatment of secondary spinal cord injury. — PubMed · 2023 · Journal Article
- Macrophages play a leading role in determining the direction of astrocytic migration in spinal cord injury via ADP-P2Y1R axis. — PubMed · 2023 · Preprint
- The mechanism of human neural stem cell secretomes improves neuropathic pain and locomotor function in spinal cord injury rat models: through antioxidant, anti-inflammatory, anti-matrix degradation, and neurotrophic activities. — PubMed · 2023 · Journal Article
- Molecular Mechanisms in the Vascular and Nervous Systems following Traumatic Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Thoracic Jia-Ji electro-acupuncture mitigates low skeletal muscle atrophy and improves motor function recovery following thoracic spinal cord injury in rats. — PubMed · 2022 · Journal Article
- Lithium promotes long-term neurological recovery after spinal cord injury in mice by enhancing neuronal survival, gray and white matter remodeling, and long-distance axonal regeneration. — PubMed · 2022 · Journal Article
- Spinal cord tissue engineering using human primary neural progenitor cells and astrocytes. — PubMed · 2022 · Journal Article
- A bionic multichannel nanofiber conduit carrying Tubastatin A for repairing injured spinal cord. — PubMed · 2022 · Journal Article
- Imatinib inhibits pericyte-fibroblast transition and inflammation and promotes axon regeneration by blocking the PDGF-BB/PDGFRβ pathway in spinal cord injury. — PubMed · 2022 · Journal Article
- Plasma Cytokines Level and Spinal Cord MRI Predict Clinical Outcome in a Rat Glial Scar Cryoinjury Model. — PubMed · 2022 · Journal Article
- Capacity of astrocytes to promote axon growth in the injured mammalian central nervous system. — PubMed · 2022 · Journal Article
- Protective role of ethyl pyruvate in spinal cord injury by inhibiting the high mobility group box-1/toll-like receptor4/nuclear factor-kappa B signaling pathway. — PubMed · 2022 · Journal Article
- Ruxolitinib attenuates secondary injury after traumatic spinal cord injury. — PubMed · 2022 · Journal Article
- Spatiotemporal dynamics of the cellular components involved in glial scar formation following spinal cord injury — Crossref · 2022 · journal-article
- Mechanisms of ginsenosides exert neuroprotective effects on spinal cord injury: A promising traditional Chinese medicine. — PubMed · 2022 · Journal Article
- PTBP-1 and TNF-α/NF-κB are involved in repair mechanisms of human umbilical cord mesenchymal stem cell transplantation in mice with spinal cord injury. — PubMed · 2022 · Journal Article
- Bu Shen Huo Xue decoction promotes functional recovery in spinal cord injury mice by improving the microenvironment to promote axonal regeneration. — PubMed · 2022 · Journal Article
- Neuronal reprogramming in treating spinal cord injury. — PubMed · 2022 · Journal Article
- Astrocyte transplantation for repairing the injured spinal cord. — PubMed · 2022 · Journal Article
- The Composition and Cellular Sources of CSPGs in the Glial Scar After Spinal Cord Injury in the Lamprey. — PubMed · 2022 · Journal Article
- The Inflammatory Response after Moderate Contusion Spinal Cord Injury: A Time Study. — PubMed · 2022 · Journal Article
- Application of Collagen-Based Scaffolds for the Treatment of Spinal Cord Injuries in Animal Models: A Literature Update. — PubMed · 2022 · Journal Article
- FANCC deficiency mediates microglial pyroptosis and secondary neuronal apoptosis in spinal cord contusion. — PubMed · 2022 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-09-29 Collection window: 2026-09-16 – 2026-09-29 | matched in this collection walk 0 · accumulated records across collection walks 4 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 851162 · accumulated records across collection walks 50 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 7 · accumulated records across collection walks 1725 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("glial scar" OR "astrogliosis" OR "fibrotic scar") - Crossref
spinal cord injury glial scar astrogliosis - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Gliosis"[MeSH Terms] OR "Cicatrix"[MeSH Terms] OR "glial scar"[Title/Abstract] OR "astrogliosis"[Title/Abstract] OR "fibrotic scar"[Title/Abstract])