A subject this map covers
Inflammation and immune response
What belongs here
What immune cells do after injury — both as damage and as a necessary part of healing.
What does not belong here, however close it looks
Infection and sepsis are clinical management, a separate subject.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 769 records · 1981–2027
- Indexed as work in animals: 1704 records · 1975–2027
- Indexed as laboratory work: 73 records · 2001–2026
- The source has not said who or what was studied: 639 records · 1998–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3185 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Ferroptosis-associated myeloid cell heterogeneity and inflammatory amplification following spinal cord injury. — PubMed · 2026 · Journal Article
- PLX5622 did not alter anxiety-like behaviour and showed limited microglial depletion efficacy in a spinal cord injury model in female rats. — PubMed · 2026 · Journal Article
- Dual-targeting nanoparticles enhance microglial P2Y12R expression to promote neuronal mitophagy for repairing spinal cord injury. — PubMed · 2026 · Journal Article
- Temporal Biomarker Profiles Following Non-Surgical Spinal Cord Concussion. — PubMed · 2026 · Journal Article
- Repetitive trans-spinal magnetic stimulation promotes repair in inflammatory spinal cord injury through sex-dependent immune modulation. — PubMed · 2026 · Journal Article
- Inflachromene Blocks Neuronal HMGB1 Translocation to Mitigate Hippocampal TLR4-NF-κB-Mediated Neuroinflammation and Depression-Like Behavior After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Electroacupuncture alleviates depression-like behavior after spinal cord injury via SIRT1/HMGB1 signaling axis mediated ferroptosis. — PubMed · 2026 · Journal Article
- circ_0044235 exacerbates neuroinflammation and apoptosis following spinal cord injury by targeting miR-338-5p. — PubMed · 2026 · Journal Article
- Trimethylamine N-Oxide Aggravates Neuro-inflammation in Spinal Cord Injury Through NLRP3 Inflammasome Activation in Microglia. — PubMed · 2026 · Journal Article
- Celastrol treatment attenuates the inflammatory response in Alzheimer's disease model mice. — PubMed · 2026 · Journal Article
- Identification of repopulated microglia-associated genes in microglia depleted/repopulated mice after spinal cord injury. — PubMed · 2026 · Journal Article
- In Situ Forming ROS-Scavenging Hydrogel with a STING Inhibitor Improves Recovery After Acute Spinal Cord Injury by Modulating Inflammatory Microenvironment. — PubMed · 2026 · Journal Article
- Kakkalide promotes spinal cord injury repair by regulating microglial M2 polarization via mitophagy. — PubMed · 2026 · Journal Article
- Low-Intensity Pulsed Ultrasound Promotes Spinal Cord Injury Recovery by Regulating Microglia-Mediated Neuroinflammation. — PubMed · 2026 · Journal Article
- Short-chain fatty acids modulate regulatory T cells via NF-κB signaling pathway in a rat model of spinal cord injury. — PubMed · 2026 · Journal Article
- Spatiotemporal Co-Delivery of Hydrogen and Magnesium via Microneedle Patches for Neuroinflammation Modulation After Spinal Cord Injury: A Multi-Modal In Vivo Study. — PubMed · 2026 · Journal Article
- SYK-dependent lipid handling in monocyte-derived macrophages governs functional recovery after spinal cord injury. — PubMed · 2026 · Journal Article
- Wnt5a-Induced Exosomes From Bone Marrow Mesenchymal Stem Cells Promote Spinal Cord Injury Repair by Modulating Immune Cell Phenotypes and Alleviating Neuroinflammation via the NF-κB Pathway. — PubMed · 2026 · Journal Article
- Zinc protects against neuroinflammation after spinal cord injury by regulating mitophagy-dependent mtDNA-cGAS-STING signaling. — PubMed · 2026 · Journal Article
- Injectable Metal-Free Carbon Dot-Integrated Hydrogel for Regulating Inflammation via Macrophage Metabolic Reprograming in Spinal Cord Injury Therapy. — PubMed · 2026 · Journal Article
- Propentofylline and Interleukin-4 Modulate Lesion-Associated Myeloid Responses and Improve Functional Recovery After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- TIA1-mediated stress granules inhibit the neuroinflammation and neurodegeneration after spinal cord injury through LCN2 signaling. — PubMed · 2026 · Journal Article
- Anti-inflammatory treatment confirms rsfMRI and TSPO PET as biomarkers of functional connectivity and neuroinflammation in rat contusion spinal cord injuries. — PubMed · 2026 · Journal Article
- Combined use of Bumetanide and MGE cell transplantation alleviates neuropathic pain and its mechanism after spinal cord injury in mice. — PubMed · 2026 · Journal Article
- Photobiomodulation Therapy with Zinc Oxide/Pheophorbide-a Nanoflakes Enhances Neurovascular Repair in Spinal Cord Injury Evidenced Using Photoacoustic Imaging. — PubMed · 2026 · Journal Article
- Obacunone Promotes Functional Recovery After Spinal Cord Injury by Attenuating Neuroinflammation by Targeting the TLR4/MyD88/p38 MAPK Pathway. — PubMed · 2026 · Journal Article
- Spinal Cord Stimulation Alleviates Spinal Cord Injury-Induced Neuropathic Pain Via m(5)C-Dependent Regulation of TRAF2. — PubMed · 2026 · Journal Article
- APOE-mediated lipid transport prevents C1q-related synaptic loss after spinal cord injury via attenuating macrophage lipid stress. — PubMed · 2026 · Journal Article
- Angiopep-2-engineered extracellular vesicles derived from spinal cord injury-responsive brown adipose tissue for targeted neuroinflammation modulation. — PubMed · 2026 · Journal Article
- NanoScript-Enabled Nonviral Transient Repression of Phosphatase and Tensin Homolog for Axonal Regeneration and Central Nervous System Injury Repair. — PubMed · 2026 · Journal Article
- Anti-inflammatory role of methylprednisolone in the hippocampus prevents depressive-like behavior after spinal cord injury in rats. — PubMed · 2026 · Journal Article
- Intracellular small molecule/ion storm from Ca-phytate nanoparticle synergizes neural stem cell therapy and immunomodulation in spinal cord injury. — PubMed · 2026 · Journal Article
- Midkine Overexpression Promotes Functional Recovery After Spinal Cord Injury by Enhancing Microglial Efferocytosis Via LRP-1. — PubMed · 2026 · Journal Article
- NG2 glia promote injured spinal cord repair through neuronal transdifferentiation and keratins expression in juvenile mice. — PubMed · 2026 · Journal Article
- Persistent histone H3K27 acetylation contributes to excessive scar formation after spinal cord injury through the regulation of microglial cholesterol accumulation. — PubMed · 2026 · Journal Article
- Sequential dual-drug delivery biomimetic hydrogel for temporal orchestration of acute neuroprotection and chronic regeneration in spinal cord injury. — PubMed · 2026 · Journal Article
- FGF4 activates FGFR1 - PI3K/AKT signaling to enhance Clec10a-mediated intracellular myelin debris processing and promote spinal cord repair. — PubMed · 2026 · Journal Article
- Regional Molecular Diversity in Chronic Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Nanoparticle-Assembled Multifaceted Hydrogel Therapy Promotes Functional Recovery After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- LPS Pre-Conditioned Olfactory Ensheathing Cells Derived Extracellular Vesicle Regulate Microglia Polarization Through mir-1224/CD44/SLC7A11 Axis Following Spinal Cord Injury. — PubMed · 2026 · Journal Article
- NNT inhibits microglial activation via mitochondrial oxidative stress in spinal cord injury. — PubMed · 2026 · Journal Article
- TMEM106A deficiency in microglia attenuates functional recovery after spinal cord injury by exacerbating neuroinflammation. — PubMed · 2026 · Journal Article
- A dual-action nanoparticle approach for spinal cord injury treatment: ferroptosis inhibition, inflammation control, and Myelin preservation. — PubMed · 2026 · Journal Article
- Modulation of the inflammatory microenvironment after SCI to achieve enhanced nerve regeneration using pteryxin-releasing methylacrylated hyaluronic acid. — PubMed · 2026 · Journal Article
- Columbianadin improves M1 polarization of microglia after spinal cord injury by stabilizing PTEN and inhibiting the PI3K/AKT pathway. — PubMed · 2026 · Journal Article
- Ganoderma microsporum-derived fungal immunomodulatory protein (GMI) promotes functional recovery after spinal cord injury by modulating anti-inflammation and enhancing regeneration. — PubMed · 2026 · Journal Article
- Immuno-Neuroprotectants Facilitate Neurological Recovery via Sequestration of Neutrophil Extracellular Traps (NETs) and Promotion of Neuroregeneration. — PubMed · 2026 · Journal Article
- Local release of fibroblast growth factor 21 and cannabidiol promoting spinal cord nerve injury repair through activation of cannabinoid receptor 2. — PubMed · 2026 · Journal Article
- Morusin Alleviates Spinal Cord Injury in Rats by Regulating Macrophage Reprogramming Through Targeting RELA and NRF2. — PubMed · 2026 · Journal Article
- Multi-omics analysis of ketogenic diet-mediated neural repair in spinal cord injury: Targeting of lysosomal autophagy through CTSB/LAMP2 regulation. — PubMed · 2026 · Journal Article
- Naringenin alleviates spinal cord injury by ameliorating macrophage/microglia autophagy via progranulin stabilisation. — PubMed · 2026 · Journal Article
- Phillyrin Ameliorates Traumatic Spinal Cord Injury by Inhibiting Inflammation, Oxidative Stress, and Pyroptosis Through Modulation of the Nrf2/HO-1 Signaling Pathway. — PubMed · 2026 · Journal Article
- Restoration of Microglia-Dependent Signaling Networks Drives Tissue Repair and Functional Recovery After Spinal Cord Injury in Microglia-Depleted Mice. — PubMed · 2026 · Journal Article
- TREM2 Facilitates Myelin Debris Clearance but Exacerbates Chronic Inflammation and Fibrosis After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Clec7a-targeted Res@GelMA hydrogels regulate macrophage polarization to reduce neuroinflammation and promote spinal cord repair. — PubMed · 2026 · Journal Article
- Silencing of Ifi27l2a Attenuates Inflammation After Spinal Cord Injury by Regulating Microglial Polarization via JAK2/STAT3 Signaling. — PubMed · 2026 · Journal Article
- Exogenous IL-33 mitigates inflammatory responses by suppressing the NF-Κb signaling pathway, promoting blood-spinal cord barrier repair and neural functional recovery. — PubMed · 2026 · Journal Article
- Modulation of inflammatory and regenerative responses by Galectin-3 after spinal cord injury in wild-type and Galectin-3 knockout mice. — PubMed · 2026 · Journal Article
- Celastrol alleviates acute spinal cord injury by inhibiting microglial pyroptosis via the Neat1/NLRP3 pathway. — PubMed · 2026 · Journal Article
- Proton-Activated Chloride Channel Modulates Motor Function after Acute Spinal Cord Injury. — PubMed · 2026 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 3 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851312 · this programme has 48 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 29 · this programme has 3219 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroinflammation" OR "microglia" OR "immune response") - Crossref
spinal cord injury neuroinflammation microglia - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neurogenic Inflammation"[MeSH Terms] OR "Microglia"[MeSH Terms] OR "Neuroimmunomodulation"[MeSH Terms] OR "neuroinflammation"[Title/Abstract] OR "microglia"[Title/Abstract] OR "immune response"[Title/Abstract])