A subject this map covers
Inflammation and immune response
What belongs here
What immune cells do after injury — both as damage and as a necessary part of healing.
What does not belong here, however close it looks
Infection and sepsis are clinical management, a separate subject.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 769 records · 1981–2027
- Indexed as work in animals: 1704 records · 1975–2027
- Indexed as laboratory work: 73 records · 2001–2026
- The source has not said who or what was studied: 639 records · 1998–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3185 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Andrographolide attenuates neuroinflammation and apoptosis after spinal cord injury via PI3K-Akt pathway activation. — PubMed · 2026 · Journal Article
- Edaravone attenuates ACSL4-dependent ferroptosis in spinal motor neurons following cardiac arrest in rats. — PubMed · 2026 · Journal Article
- Exosomal PSMD1 Derived From Dental Pulp Mesenchymal Stem Cells Promotes Microglial M2 Polarization to Alleviate Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Quercetin regulates lipid metabolism and inflammatory microenvironment of microglia after spinal cord injury through activating the butyrate-FFAR2/AMPK/TFEB gut-brain axis signaling pathway. — PubMed · 2026 · Journal Article
- 6-gingerol Attenuates Inflammatory Response in Rats With Spinal Cord Injury by Reducing NLRP3-mediated Microglial Pyroptosis. — PubMed · 2026 · Journal Article
- Every-Other-Day Fasting Prehabilitation Attenuates Secondary Injury Following Spinal Cord Injury and Is Associated with Stage-Dependent SREBP1-Related Metabolic-Immune Remodeling. — PubMed · 2026 · Journal Article
- Integrative single-cell and bulk transcriptomic analyses identify a microglia-associated NAGLU signature linked to disulfidptosis-associated transcriptional patterns after spinal cord injury. — PubMed · 2026 · Journal Article
- Astrocyte-derived exosome-mediated siRNA delivery combined with quercetin-Mn complex promotes neural repair in spinal cord injury. — PubMed · 2026 · Journal Article
- Isoquercitrin-loaded adipose-derived stem cell exosomes synchronize immunomodulation and neurovascular remodeling to accelerate spinal cord regeneration. — PubMed · 2026 · Journal Article
- NINJ1 monoclonal antibody alleviates neuroinflammation and promotes functional recovery after spinal cord injury by suppressing pyroptosis-mediated DAMPs release. — PubMed · 2026 · Journal Article
- Knockdown of DLGAP5 inhibits microglia activation in spinal cord injury rats through limiting NF-κB activation. — PubMed · 2026 · Journal Article
- Nanoformulated fingolimod attenuates NLRP3 inflammasome activation and promotes functional recovery in a rat model of spinal cord injury. — PubMed · 2026 · Journal Article
- Recombinant Artemin-Fc Fusion Protein Attenuates TLR4/NF-κB-Associated Neuroinflammation and Modulates Inhibitory/Excitatory Synaptic Marker Expression After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Skeletal muscle lysate derived macroporous hydrogel repairs spinal cord injury via immunoregulation and axon regeneration. — PubMed · 2026 · Journal Article
- Targeting Dnmt3a/m5C/RelA Axis Attenuates Microglia Inflammatory Response and Improves Postoperative Recovery in Chronic Compressive Cervical Spinal Cord Injury. — PubMed · 2026 · Journal Article
- TREM1 inhibition via LP17 alleviates secondary spinal cord injury by activating AMPKα-PINK1-parkin-dependent microglial mitophagy. — PubMed · 2026 · Journal Article
- Cell-type-specific m1A dynamics are associated with microglial phenotypic transition and neuronal metabolic adaptation during spinal cord injury. — PubMed · 2026 · Journal Article
- Betulinic Acid Promotes Motor Function Recovery After Spinal Cord Injury by Inhibiting Apoptosis Through Myc/NF-κB Signaling Pathway. — PubMed · 2026 · Journal Article
- [Mechanisms of Piezo1-mediated microglial ferroptosis in inhibiting spinal cord injury repair]. — PubMed · 2026 · English Abstract
- Targeting microglial MyD88 reprograms injury-activated microglia and promotes spinal cord repair via TGF-β signaling and biomimetic nanodelivery. — PubMed · 2026 · Journal Article
- Thiolated Chitosan-Stearic Acid Thiol-Linked Biomimetic Hydrogels for Axonal Regrowth and Neuronal Tissue Regeneration. — PubMed · 2026 · Journal Article
- Electroacupuncture-modulated DHCR24 facilitates spinal cord injury recovery by attenuating apoptosis and neuroinflammation via the Wnt signaling pathway. — PubMed · 2026 · Journal Article
- Ddx20, DEAD-box helicase 20 is essential for maintaining microglial homeostasis. — PubMed · 2026 · Journal Article
- From SHP2 to DDR1-ERK: A critical signaling axis controlling microglial activation and neuropathic pain after spinal cord injury. — PubMed · 2026 · Journal Article
- Identification of PANoptosis-related biomarkers in spinal cord injury (SCI) through multi-omics analysis and machine learning. — PubMed · 2026 · Journal Article
- miR-19a-3p and miR-19b-3p Promote Microglia Activation Associated With Neuroinflammation. — PubMed · 2026 · Journal Article
- Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar-Limited Repair in Adult Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Tetramethylpyrazine promotes spinal cord injury repair by modulating macrophage M1/M2 polarization via inhibition of the IL-6/JAK2/STAT3 pathway. — PubMed · 2026 · Journal Article
- The Canonical Wnt Surrogate Agonist scFv-Dkk1c Ameliorates Spinal Cord Injury in Rats. — PubMed · 2026 · Journal Article
- Astrocyte-microglia crosstalk via CSF1 and IFN-β promotes central nervous system repair. — PubMed · 2026 · Journal Article
- Elevated phagocytic capacity directs innate spinal cord repair. — PubMed · 2026 · Journal Article
- The microglia-derived protein Sema4ab attenuates regenerative neurogenesis after spinal cord injury in zebrafish. — PubMed · 2026 · Journal Article
- Cel-LDH dual-functional nanotherapy simultaneously promotes microglial efferocytosis and alleviates neuronal apoptosis for spinal cord injury recovery. — PubMed · 2026 · Journal Article
- Varenicline-mediated cholinergic activation through α4β2 nAChR inhibits microglial neuroinflammation and alleviates neuropathic pain and depression following spinal cord injury. — PubMed · 2026 · Journal Article
- Glutathione-Chitosan Modified Methyl Eugenol Liposomes Promote Spinal Cord Injury Repair by Alleviating Neuroinflammation. — PubMed · 2026 · Journal Article
- Depleting non-resolving neuroinflammation in chronic spinal cord injury attenuates thermal hypersensitivity. — PubMed · 2026 · Journal Article
- Dihydromyricetin (DHM) Inhibits Microglial Pyroptosis and Oxidative Stress After Spinal Cord Injury by Promoting STING-Mediated Autophagy. — PubMed · 2026 · Journal Article
- Liproxstatin-1 improves functional recovery after acute spinal cord injury by inhibiting ferroptosis-induced inflammation. — PubMed · 2026 · Journal Article
- Mechanism of Qufeng Huoxue decoction in treating paclitaxel-induced peripheral neuropathy based on network pharmacology and molecular docking. — PubMed · 2026 · Journal Article
- A reparative neutrophil subpopulation accelerates spinal cord regeneration in zebrafish by controlling macrophage inflammation via Il-4. — PubMed · 2026 · Journal Article
- Nanozyme-Switched Efferocytosis Initiation Platform Orchestrates Pathological Network Reprogramming to Promote Functional Recovery after Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Sex differences in peripheral and local immune responses following spinal cord injury. — PubMed · 2026 · Journal Article
- LEP Knockdown Improves Functional Recovery After Spinal Cord Injury and Potentially Regulates Microglial Polarization via JAK-STAT Signaling Pathway. — PubMed · 2026 · Journal Article
- ABCA1-mediated lipid efflux restrains oxidative stress and neuroinflammation after spinal cord injury. — PubMed · 2026 · Journal Article
- Indole-3-propionic acid inhibits astrocyte inflammation and promotes motor function recovery after spinal cord injury via the AhR/NF-κB/MAPK axis. — PubMed · 2026 · Journal Article
- Multi-omics mapping identifies a C/EBPβ-S100a4⁺ macrophage axis as a therapeutic target in acute spinal cord injury. — PubMed · 2026 · Journal Article
- Identification of a mitochondrial biomarker signature linking neuroinflammation to neuronal dysfunction in spinal cord injury. — PubMed · 2026 · Journal Article
- SGK1 inhibition supports neuroprotection in spinal cord injury by suppressing oxidative stress and AIM2 activation via FoxO1 mediated mitophagy. — PubMed · 2026 · Journal Article
- Activation of GLP-1R ameliorates microglial pyroptosis after spinal cord injury by restoring FANCC expression. — PubMed · 2026 · Journal Article
- Acute Administration of Ampakine CX1739 after Cervical Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Agarotetrol attenuates spinal cord injury by targeting PPARγ to modulate microglial activation. — PubMed · 2026 · Journal Article
- A novel cannabidiol-derived small molecule ameliorates lower urinary tract dysfunction in mice with spinal cord injury via suppressing neuroinflammation. — PubMed · 2026 · Journal Article
- DLK inhibition has sex-specific effects on neuroprotection and locomotor recovery after spinal cord injury. — PubMed · 2026 · Journal Article
- Hyaluronic Acid Hydrogel-Mediated Delivery of MSC-Derived Exo-FGF21 Promotes Spinal Cord Injury Repair via STAT3/SOCS3 Signaling. — PubMed · 2026 · Journal Article
- Methyltransferase-like protein 16 suppresses spinal cord injury by regulating microglia polarization via N6-methyladenosine-modified downregulation of MCEMP1. — PubMed · 2026 · Journal Article
- Niacin promotes motor function recovery after spinal cord injury via Hcar2-dependent microglia immunometabolic regulation. — PubMed · 2026 · Journal Article
- NR4A1 attenuates neuroinflammation after spinal cord injury by modulating microglial polarization via negatively regulating the VAV1 pathway. — PubMed · 2026 · Journal Article
- Spatiotemporal PET imaging of P2X7R-driven neuroinflammation using [(18)F]GSK1482160 after experimental acute spinal cord injury in mice. — PubMed · 2026 · Journal Article
- Unveiling distinct neuroimmune responses in mouse models of cervical spinal cord injury: Hemisection versus hemicontusion. — PubMed · 2026 · Journal Article
- Sortilin is Associated with PGRN-Mediated Endoplasmic Reticulum Stress and Activation of Microglia in a Rat Model of Degenerative Cervical Myelopathy. — PubMed · 2026 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 3 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851312 · this programme has 48 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 29 · this programme has 3219 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroinflammation" OR "microglia" OR "immune response") - Crossref
spinal cord injury neuroinflammation microglia - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neurogenic Inflammation"[MeSH Terms] OR "Microglia"[MeSH Terms] OR "Neuroimmunomodulation"[MeSH Terms] OR "neuroinflammation"[Title/Abstract] OR "microglia"[Title/Abstract] OR "immune response"[Title/Abstract])