A subject this map covers
Inflammation and immune response
What belongs here
What immune cells do after injury — both as damage and as a necessary part of healing.
What does not belong here, however close it looks
Infection and sepsis are clinical management, a separate subject.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 769 records · 1981–2027
- Indexed as work in animals: 1704 records · 1975–2027
- Indexed as laboratory work: 73 records · 2001–2026
- The source has not said who or what was studied: 639 records · 1998–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3185 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- GDF11 alleviates spinal cord injury in rats by modulating microglia polarization through Smad2/3 and MAPK/NFκB signaling pathways. — PubMed · 2025 · Journal Article
- Nanoparticles loaded with a CSF1R antagonist selectively depletes microglial cells and modulates inflammation in spinal cord injury. — PubMed · 2025 · Journal Article
- Effects of age on the response to spinal cord injury: optimizing the larval zebrafish model. — PubMed · 2025 · Journal Article
- From Molecular Docking to Rat Models: Butyrate From a High-Fiber Diet Inhibits HDAC1 and NLRP3 Inflammasome to Alleviate Oxidative Stress and Inflammation After Spinal Cord Injury. — PubMed · 2025 · Journal Article
- GLP-1R activation restores Gas6-driven efferocytosis in senescent foamy macrophages to promote neural repair. — PubMed · 2025 · Journal Article
- Increased spinal adenosine after subacute cervical injury correlates with sustained upregulation of CD39 and CD73 in microglia. — PubMed · 2025 · Journal Article
- Injectable ROS homeostasis protective hydrogel inhibiting microglial ferroptosis through the Nrf2/Slc7a11/Gpx4 to alleviate neuropathic pain and promote spinal cord injury repair. — PubMed · 2025 · Journal Article
- Investigating the Effects of Epac2 Activation in an In Vitro Cortical Mechanical Injury Model for Central Nervous System Repair. — PubMed · 2025 · Journal Article
- LncRNA ZFAS1 Combined with SRSF1 Regulate CNPY2 Expression and Leads to Microglia Endoplasmic Reticulum Stress-Induced Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Long-term dynamics of the spinal cord injury neuroinflammatory response and sensory dysfunction in female mice. — PubMed · 2025 · Journal Article
- Microglia-Derived Cell Membranes Encapsulated Schisandra chinensis Polysaccharide-Zinc Complex for the Treatment of Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Multifunctional albumin-based hydrogel/microglia composites enhancing the therapeutic potential of neonatal microglia in complex spinal cord injuries and sealing dural rupture. — PubMed · 2025 · Journal Article
- Phenserine Mitigates Neuroinflammation, Apoptosis, and Behavioural Deficits to Enhance Motor Function and Recovery in a Mouse Model of Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Piezo1 deletion ameliorates inflammation and functional recovery in spinal cord injury through altering microglia/macrophage phenotype. — PubMed · 2025 · Journal Article
- Spatiotemporal R-loop accumulation orchestrates microenvironmental remodeling after spinal cord injury. — PubMed · 2025 · Journal Article
- Targeting RelA/NLRP3/CCL3 axis mitigates microglia inflammatory response and promotes recovery after spinal cord injury. — PubMed · 2025 · Journal Article
- The Analgesic and Antispastic Effects of Epidural Spinal Stimulation Depending on the Frequency and Intensity After Spinal Cord Injury. — PubMed · 2025 · Journal Article
- TREM2 Impedes Recovery After Spinal Cord Injury by Regulating Microglial Lysosomal Membrane Permeabilization-Mediated Autophagy. — PubMed · 2025 · Journal Article
- Repetitive Trans-spinal Magnetic Stimulation Suppresses Microglia to Engulf Synapse and Promotes Nerve Repairment via cGAS-STING Signaling Pathway after Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Breviscapine regulates lipid metabolism of microglia via the ADORA1/PPARα/ACOX1 pathway to promote spinal cord injury recovery. — PubMed · 2025 · Journal Article
- Effect of ACTH4-10Pro8-Gly9-Pro10 on anti-inflammatory cytokine (IL-4, IL-10, IL-13) expression in acute spinal cord injury models (male Sprague Dawley rats). — PubMed · 2025 · Journal Article
- Forced polarisation of microglia by IL-13 is modified by inflammatory and microenvironmental context. — PubMed · 2025 · Journal Article
- The effect of PU/MWCNT nanofiber scaffolds containing hesperidin nanoparticles and mesenchymal stem cells on the microglia and astrocyte phenotype in the spinal cord injury model. — PubMed · 2025 · Journal Article
- Commercial cytokine assay on equine cerebrospinal fluid does not distinguish equine degenerative myeloencephalopathy from cervical vertebral stenotic myelopathy. — PubMed · 2025 · Journal Article
- DCAAA mitigates neuroinflammation and microglial pyroptosis in spinal cord injury by inhibiting PI3K/AKT/NF-κB and NLRP3/caspase-1/GSDMD signaling. — PubMed · 2025 · Journal Article
- Bilirubin Alleviates Spinal Cord Injury by Enhancing SOCS3-Mediated Anti-Inflammatory Effects via Gas6-Axl Signaling. — PubMed · 2025 · Journal Article
- Ganoderma lucidum low molecular weight polysaccharide promotes the repair of spinal cord injury through anti-inflammatory and antioxidant. — PubMed · 2025 · Journal Article
- Glial cell crosstalk in the local microenvironment following spinal cord injury. — PubMed · 2025 · Journal Article
- Hypoxia-Inducible Factor-1α-Induced Astrocytic D-Dopachrome Tautomerase Activates Microglial Inflammatory Response following Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Consequences of Adhesion Molecule Close Homolog of L1 Deficiency for Neurons and Glial Cells in the Mouse Spinal Cord After Injury. — PubMed · 2025 · Journal Article
- Enhanced locomotor recovery in mice lacking GlcNAc6ST1 and GlcNAc6ST4 following spinal cord injury. — PubMed · 2025 · Journal Article
- Preventive and therapeutic effects of Tanshinone IIA on spinal cord injury without radiographic abnormality by regulating microglial phenotype polarization. — PubMed · 2025 · Journal Article
- Tibolone Improves Motor Recovery and Regulates Neuroinflammation and Gliosis in a Model of Traumatic Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Loss of RhoA in microglia disables glycolytic adaptation and impairs spinal cord injury recovery through Arhgap25/HIF-1α pathway. — PubMed · 2025 · Journal Article
- Sparc Suppresses Microglial Neuroinflammation and Promotes Axonal Regeneration by Interacting With Uba52. — PubMed · 2025 · Journal Article
- Per2 deficiency in microglia alleviates motor dysfunction by inhibiting ferroptosis in spinal cord injury. — PubMed · 2025 · Journal Article
- Mechanistic Study of Jaceosidin in Regulating Secondary Inflammation After Spinal Cord Injury in Mouse by Inhibiting PKM2 Activity. — PubMed · 2025 · Journal Article
- Astrocytic ET-1 System Determines Microglia Phenotype Following Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Lentiviral Injection of Inter-α-Trypsin Inhibitor Heavy Chain 4 Promotes Female Spinal Cord Injury Mice Recuperation by Diminishing Peripheral and Central Inflammation. — PubMed · 2025 · Journal Article
- Microglial IKKβ Alters Central and Peripheral Immune Activity at Distinct Time Points After Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Microglial landscape and signaling in spinal cord injury. — PubMed · 2025 · Journal Article
- Multi-omics characterization of oncosis in spinal cord injury. — PubMed · 2025 · Journal Article
- Silencing of SH3BP2 Inhibits Microglia Activation Via the JAK/STAT Signaling in Spinal Cord Injury Models. — PubMed · 2025 · Journal Article
- Magnetically Driven Biomimetic Microrobot Loaded with Eleutheroside B for Targeted Delivery and Neural Repair in Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Loss of TRPV4 is insufficient to promote repair in a spinal cord injury contusion model. — PubMed · 2025 · Journal Article
- Effect of Dynamin-2 Gene Modified OECs on Functional and Molecular Neuroprotection After Spinal Cord Injury in Rats. — PubMed · 2025 · Journal Article
- Phosphodiesterase 2A as a Therapeutic Target for Relieving Mechanical Allodynia and Modulating Microglial Polarization in Neuropathic Pain Models Following Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Molecular pathology of acute spinal cord injury in middle-aged mice. — PubMed · 2025 · Journal Article
- Bone marrow mesenchymal stem cells-derived exosomal miR-24-3p alleviates spinal cord injury by targeting MAPK9 to inhibit the JNK/c-Jun/c-Fos pathway. — PubMed · 2025 · Journal Article
- Dynamic microglia/macrophage infiltration during spinal cord regeneration in larval sea lamprey. — PubMed · 2025 · Journal Article
- Engineered Exosome-Loaded Silk Fibroin Composite Hydrogels Promote Tissue Repair in Spinal Cord Injury Via Immune Checkpoint Blockade. — PubMed · 2025 · Journal Article
- Exosomal lncRNA RMRP-shuttled by Olfactory Mucosa-Mesenchymal Stem Cells Suppresses Microglial Pyroptosis to Improve Spinal Cord Injury via EIF4A3/SIRT1. — PubMed · 2025 · Journal Article
- Hyaluronan-bisphosphonate conjugate: A macromolecular anti-inflammatory agent and gas delivery system for neuroimmunomodulation in spinal cord injury. — PubMed · 2025 · Journal Article
- Metabolic reprogramming in astrocytes prevents neuronal death through a UCHL1/PFKFB3/H4K8la positive feedback loop. — PubMed · 2025 · Journal Article
- Pectolinarin Promotes Functional Recovery after Spinal Cord Injury by Regulating Microglia Polarization Through the PI3K/AKT Signaling Pathway. — PubMed · 2025 · Journal Article
- Thoracic Spinal Cord Contusion Impacts on Lumbar Enlargement: Molecular Insights. — PubMed · 2025 · Journal Article
- Identifying Microglia and Peripheral Infiltrating Macrophages in the Injured Spinal Cords Using Flow Cytometry. — PubMed · 2025 · Journal Article
- Xanthoxylin Regulating the Inflammatory Microenvironment After Spinal Cord Injury Through Inhibition of the NF-κB Signaling Pathway. — PubMed · 2025 · Journal Article
- Betulinic acid enhances autopahgy to promote microglial M2 polarization and alleviate inflammation via AMPK-HDAC5-KLF2 signaling pathways in spinal cord injury. — PubMed · 2025 · Journal Article
- [Effect of removing microglia from spinal cord on nerve repair after spinal cord injury in mice]. — PubMed · 2025 · English Abstract
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 3 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851312 · this programme has 48 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 29 · this programme has 3219 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroinflammation" OR "microglia" OR "immune response") - Crossref
spinal cord injury neuroinflammation microglia - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neurogenic Inflammation"[MeSH Terms] OR "Microglia"[MeSH Terms] OR "Neuroimmunomodulation"[MeSH Terms] OR "neuroinflammation"[Title/Abstract] OR "microglia"[Title/Abstract] OR "immune response"[Title/Abstract])