A subject this map covers
Inflammation and immune response
What belongs here
What immune cells do after injury — both as damage and as a necessary part of healing.
What does not belong here, however close it looks
Infection and sepsis are clinical management, a separate subject.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 769 records · 1981–2027
- Indexed as work in animals: 1704 records · 1975–2027
- Indexed as laboratory work: 73 records · 2001–2026
- The source has not said who or what was studied: 639 records · 1998–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3185 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Montelukast Improves Urinary Bladder Function After Complete Spinal Cord Injury in Rats. — PubMed · 2025 · Journal Article
- P2Y6R Inhibition Induces Microglial M2 Polarization by Promoting PINK1/Parkin-Dependent Mitophagy After Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Polygonati Rhizoma polysaccharide suppresses microglial activation and promotes functional recovery of spinal cord via improving intestinal microbiota. — PubMed · 2025 · Journal Article
- Preemptive Propofol Administration in Spinal Cord Injury: Effects on Pain-Induced Hypertension, Neuroinflammation, and Functional Recovery in Rats. — PubMed · 2025 · Journal Article
- Role of MS4A7 in Regulating Microglial Polarization and Neuroinflammation in Spinal Cord Injury via the cGAS-STING-NLRP3 Axis. — PubMed · 2025 · Journal Article
- Cathepsin L Aggravates Neuroinflammation via Promoting Microglia M1 Polarization and NLRP3 Activation After Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Inhibition of the RNA Regulator HuR Mitigates Spinal Cord Injury by Potently Suppressing Post-Injury Neuroinflammation. — PubMed · 2025 · Journal Article
- Nanodrug-loaded microneedles promote scar-reduced repair after spinal cord injury by re-establishing microglial homeostasis. — PubMed · 2025 · Journal Article
- Systemic stem cell treatment rescues injured motoneurons by reducing L-selectin expression on leukocytes. — PubMed · 2025 · Journal Article
- Cannabidiol/tetrahydrocannabinol-enrich extract decreases neuroinflammation and improves locomotor outcome following spinal cord injury. — PubMed · 2025 · Journal Article
- GPx3 Promotes Functional Recovery after Spinal Cord Injury by Inhibiting Microglial Pyroptosis Through IRAK4/ROS/NLRP3 Axis. — PubMed · 2025 · Journal Article
- Hydrogen Sulfide Modulates Microglial Polarization and Remodels the Injury Microenvironment to Promote Functional Recovery After Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Inhibition of CD36 ameliorates mouse spinal cord injury by accelerating microglial lipophagy. — PubMed · 2025 · Journal Article
- lncRNA SNHG6 Knockdown Promotes Microglial M2 Polarization and Alleviates Spinal Cord Injury via Regulating the miR-182-5p/NEUROD4 Axis. — PubMed · 2025 · Journal Article
- Lupeol mitigates spinal cord injury by modulating microglial M1/M2 polarization via Na(+)/K(+)-ATPase-mediated mitophagy. — PubMed · 2025 · Journal Article
- Neurotrophin-3/chitosan inhibits cuproptosis-related genes to enable functional recovery after spinal cord injury. — PubMed · 2025 · Journal Article
- Reduced White Matter Damage and Lower Neuroinflammatory Potential of Microglia and Macrophages in Hri/Eif2ak1 (-/-) Mice After Contusive Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Regulation of Nrf2/GPX4 Signaling Pathway by Hyperbaric Oxygen Protects Against Depressive Behavior and Cognitive Impairment in a Spinal Cord Injury Rat Model. — PubMed · 2025 · Journal Article
- Rutin Attenuates Distraction Spinal Cord Injury by Inhibiting Microglial Inflammation Through Downregulation of P38 MAPK/NF-κB/STAT3 Pathway. — PubMed · 2025 · Journal Article
- Olfactory ensheathing cells from adult female rats are hybrid glia that promote neural repair. — PubMed · 2025 · Journal Article
- Identification of Differentially Expressed Genes in Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Dynamic phosphorylation of Fascin-1 orchestrates microglial phagocytosis and neurological recovery after spinal cord injury. — PubMed · 2025 · Journal Article
- CX3CL1-mediated neuronal "rescue signal" influences inflammation progression following spinal cord injury via microglia. — PubMed · 2025 · Journal Article
- Kanglexin attenuates spinal cord injury by modulating pyroptosis and polarization via the PKA/NF-κB signaling pathway. — PubMed · 2025 · Journal Article
- Differential changes in the microglial transcriptome between neonatal and adult mice after spinal cord injury. — PubMed · 2025 · Journal Article
- Single cell RNA sequencing after moderate traumatic brain injury: effects of therapeutic hypothermia. — PubMed · 2025 · Journal Article
- LncRNA 4933431K23Rik modulate microglial phenotype via inhibiting miR-10a-5p in spinal cord injury induced neuropathic pain. — PubMed · 2025 · Journal Article
- Repeated Administrations of Polyphenolic Extracts Prevent Chronic Reflexive and Non-Reflexive Neuropathic Pain Responses by Modulating Gliosis and CCL2-CCR2/CX3CL1-CX3CR1 Signaling in Spinal Cord-Injured Female Mice. — PubMed · 2025 · Journal Article
- Baclofen modulates the immune response after spinal cord injury with locomotor benefits. — PubMed · 2025 · Journal Article
- Baicalin ameliorates neuroinflammation by targeting TLR4/MD2 complex on microglia via PI3K/AKT/NF-κB signaling pathway. — PubMed · 2025 · Journal Article
- Combined treatment targeting Ca2+ store mediated Ca2+ release and store-operated calcium entry reduces secondary axonal degeneration and improves functional outcome after SCI. — PubMed · 2025 · Journal Article
- Depletion of Cell Adhesion Molecule L1 from Microglia and Macrophages Reduces Recovery After Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Early Pro- and Anti-Inflammatory Immune Response Induced by Probiotic Treatment After Th9 Compression: The Interplay Between Spinal Cord and Jejunum. — PubMed · 2025 · Journal Article
- Effect of Engineered Cyanobacterial Capsules on a Neurogenic Bladder after Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Intranasal Delivery of Brain-Derived Neurotrophic Factor (BDNF)-Loaded Small Extracellular Vesicles for Treating Acute Spinal Cord Injury in Rats and Monkeys. — PubMed · 2025 · Journal Article
- Mineral coated microparticles delivering Interleukin-4, Interleukin-10, and Interleukin-13 reduce inflammation and improve function after spinal cord injury in a rat. — PubMed · 2025 · Journal Article
- Validation of qMT and CEST MRI as Biomarkers of Response to Treatment After Lumbar Spinal Cord Injury in Rats. — PubMed · 2025 · Journal Article
- Electroacupuncture Improves the Motor Function in Rats with Spinal Cord Injury by Regulating UCN2-Mediated cAMP-PKA Signaling in the Spinal Cord Microenvironment. — PubMed · 2025 · Journal Article
- Sodium butyrate alleviates spinal cord injury via inhibition of NLRP3/Caspase-1/GSDMD-mediated pyroptosis. — PubMed · 2025 · Journal Article
- Calycosin regulates astrocyte reactivity and astrogliosis after spinal cord injury by targeting STAT3 phosphorylation. — PubMed · 2025 · Journal Article
- Centripetal migration and prolonged retention of microglia promotes spinal cord injury repair. — PubMed · 2025 · Journal Article
- Fidgetin-like 2 knockdown increases acute neuroinflammation and improves recovery in a rat model of spinal cord injury. — PubMed · 2025 · Journal Article
- Expression of cold-inducible RNA-binding protein in mouse spinal cord injury model. — PubMed · 2025 · Journal Article
- Certolizumab enhances spinal cord injury recovery in rats through inhibition of the TNF-α signaling pathway and neuronal apoptosis. — PubMed · 2025 · Journal Article
- DANCR knockdown alleviates neuroinflammation and functional recovery after spinal cord injury via regulating the ACTN4 / STAT3 axis. — PubMed · 2025 · Journal Article
- Microglia Promote Lymphangiogenesis Around the Spinal Cord Through VEGF-C/VEGFR3-Dependent Autophagy and Polarization After Acute Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Sports training improves motor function after spinal cord injury by regulating microtubule dynamics. — PubMed · 2025 · Journal Article
- Pectin-Zein-IPA nanoparticles promote functional recovery and alleviate neuroinflammation after spinal cord injury. — PubMed · 2025 · Journal Article
- Reawakening inflammation in the chronically injured spinal cord using lipopolysaccharide induces diverse microglial states. — PubMed · 2025 · Journal Article
- Synergistic effects of neural stem cells and ibrutinib on neural tissue repair and functional recovery in a contusion mouse model of spinal cord injury. — PubMed · 2025 · Journal Article
- Resveratrol loaded microglia-derived exosomes attenuate astrogliasis by restoring mitochondrial function to reduce spinal cord injury. — PubMed · 2025 · Journal Article
- FOXO3-induced microRNA-128-3p promotes the progression of spinal cord injury in mice via regulating NLRP3 inflammasome-mediated pyroptosis. — PubMed · 2025 · Journal Article
- Fecal microbiota transplantation promotes functional recovery in mice with spinal cord injury by modulating the spinal cord microenvironment. — PubMed · 2025 · Journal Article
- Punicalagin inhibits neuron ferroptosis and secondary neuroinflammation to promote spinal cord injury recovery. — PubMed · 2025 · Journal Article
- Urolithin A alleviates NLRP3 inflammasome activation and pyroptosis by promoting microglial mitophagy following spinal cord injury. — PubMed · 2025 · Journal Article
- Blocking the p38 MAPK Signaling Pathway in the Rat Hippocampus Alleviates the Depressive-like Behavior Induced by Spinal Cord Injury. — PubMed · 2025 · Journal Article
- NIR-Responsive Functionalized Nanoflower for Acute Spinal Cord Injury. — PubMed · 2025 · Journal Article
- CCR1 antagonist as a potential modulator of inflammatory, autophagic, and apoptotic markers in spinal cord injury. — PubMed · 2025 · Journal Article
- HSPA1A inhibits pyroptosis and neuroinflammation after spinal cord injury via DUSP1 inhibition of the MAPK signaling pathway. — PubMed · 2025 · Journal Article
- Engineered Extracellular Vesicles Modified by Angiopep-2 Peptide Promote Targeted Repair of Spinal Cord Injury and Brain Inflammation. — PubMed · 2025 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 3 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851312 · this programme has 48 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 29 · this programme has 3219 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroinflammation" OR "microglia" OR "immune response") - Crossref
spinal cord injury neuroinflammation microglia - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neurogenic Inflammation"[MeSH Terms] OR "Microglia"[MeSH Terms] OR "Neuroimmunomodulation"[MeSH Terms] OR "neuroinflammation"[Title/Abstract] OR "microglia"[Title/Abstract] OR "immune response"[Title/Abstract])