A subject this map covers
Inflammation and immune response
What belongs here
What immune cells do after injury — both as damage and as a necessary part of healing.
What does not belong here, however close it looks
Infection and sepsis are clinical management, a separate subject.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 769 records · 1981–2027
- Indexed as work in animals: 1704 records · 1975–2027
- Indexed as laboratory work: 73 records · 2001–2026
- The source has not said who or what was studied: 639 records · 1998–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3185 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- DOCK2 deficiency alleviates neuroinflammation and affords neuroprotection after spinal cord injury. — PubMed · 2025 · Journal Article
- Formoterol alters chemokine expression and ameliorates pain behaviors after moderate spinal cord injury in female mice. — PubMed · 2025 · Journal Article
- Glycolytic metabolism modulation on spinal neuroinflammation and vital functions following cervical spinal cord injury. — PubMed · 2025 · Journal Article
- H4K12 Lactylation Activated-Spp1 in Reprogrammed Microglia Improves Functional Recovery After Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Macropinocytosis enhances foamy macrophage formation and cholesterol crystallization to activate NLRP3 inflammasome after spinal cord injury. — PubMed · 2025 · Journal Article
- Zinc ions facilitate metabolic bioenergetic recovery post spinal cord injury by activating microglial mitophagy through the STAT3-FOXO3a-SOD2 pathway. — PubMed · 2025 · Journal Article
- Microglial C/EBPβ-Fcgr1 regulatory axis blocking inhibits microglial pyroptosis and improves neurological recovery. — PubMed · 2025 · Journal Article
- Nano-fiber/net artificial bionic dura mater promotes neural stem cell differentiating by time sequence external-oral administration to repair spinal cord injury. — PubMed · 2025 · Journal Article
- Broad-spectrum downregulation of inflammatory cytokines by polydopamine nanoparticles to protect the injured spinal cord. — PubMed · 2025 · Journal Article
- Cross-species comparisons between pigs and mice reveal conserved sex-specific intraspinal inflammatory responses after spinal cord injury. — PubMed · 2025 · Journal Article
- Glycosylated lysosomal membrane protein promotes tissue repair after spinal cord injury by reducing iron deposition and ferroptosis in microglia. — PubMed · 2025 · Journal Article
- Nitric Oxide-Releasing Mesoporous Hollow Cerium Oxide Nanozyme-Based Hydrogel Synergizes with Neural Stem Cell for Spinal Cord Injury Repair. — PubMed · 2025 · Journal Article
- Spinal cord injury enhances lung inflammation and exacerbates immune response following exposure to LPS. — PubMed · 2025 · Journal Article
- A reactive oxygen species-responsive hydrogel loaded with Apelin-13 promotes the repair of spinal cord injury by regulating macrophage M1/M2 polarization and neuroinflammation. — PubMed · 2025 · Journal Article
- Can minor trauma cause asymptomatic cervical spinal cord compression leading to severe cervical spinal cord injury in rats? — PubMed · 2025 · Journal Article
- SIX1 aggravates the progression of spinal cord injury in mice by promoting M1 polarization of microglia. — PubMed · 2025 · Journal Article
- A cryo-shocked M2 macrophages based treatment strategy promoting repair of spinal cord injury via immunomodulation and axonal regeneration effects. — PubMed · 2025 · Journal Article
- Microgel-encapsulated tetrandrine nanoparticles promote spinal cord repair by sustaining neuroinflammation inhibition. — PubMed · 2025 · Journal Article
- An Optimized Decellularized Extracellular Matrix from Dental Pulp Stem Cell Sheets Promotes Axonal Regeneration by Multiple Modes in Spinal Cord Injury Rats. — PubMed · 2025 · Journal Article
- ARL11 knockdown alleviates spinal cord injury by inhibiting neuroinflammation and M1 activation of microglia in mice. — PubMed · 2025 · Journal Article
- BHLHE40 regulates microglia polarization after spinal cord injury via the NF-κB pathway. — PubMed · 2025 · Journal Article
- Chitosan-Modified Hydrogel Microsphere Encapsulating Zinc-Doped Bioactive Glasses for Spinal Cord Injury Repair by Suppressing Inflammation and Promoting Angiogenesis. — PubMed · 2025 · Journal Article
- Cold atmospheric plasma-activated saline alleviates secondary injury post-SCI by inhibiting extracellular matrix remodeling and infiltration of proinflammatory macrophages. — PubMed · 2025 · Journal Article
- Down-regulation of PGAM5 attenuates spinal cord injury-induced neuronal injury by inhibiting ASK-1/p38/NF-kB signaling. — PubMed · 2025 · Journal Article
- Electroacupuncture stimulation inhibited astrogliosis and microglia polarisation to alleviate spinal cord injury via Janus kinase 2/signal transducer and activator of transcription 3 signalling pathway. — PubMed · 2025 · Journal Article
- METTL14 knockdown attenuates neuron injury and improves function recovery after spinal cord injury via regulating FGF21 in an m6A-IGF2BP1-dependent mechanism. — PubMed · 2025 · Journal Article
- Mitigating sTNF/TNFR1 activation on VGluT2 + spinal cord interneurons improves immune function after mid-thoracic spinal cord injury. — PubMed · 2025 · Journal Article
- Nonresolving Neuroinflammation Regulates Axon Regeneration in Chronic Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Resveratrol Upregulates miR-124-3p Expression to Target DAPK1, Regulating the NLRP3/Caspase-1/GSDMD Pathway to Inhibit Pyroptosis and Alleviate Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Shh Protects the Injured Spinal Cord in Mice by Promoting the Proliferation and Inhibiting the Apoptosis of Nerve Cells via the Gli1-TGF-β1/ERK Axis. — PubMed · 2025 · Journal Article
- The role of H3K27 acetylation in oxygen-glucose deprivation-induced spinal cord injury and potential for neuroprotective therapies. — PubMed · 2025 · Journal Article
- TRIM32 Inhibits NEK7 Ubiquitylation-Dependent Microglia Pyroptosis After Spinal Cord Injury. — PubMed · 2025 · Journal Article
- IL-18 Blockage Reduces Neuroinflammation and Promotes Functional Recovery in a Mouse Model of Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Dynamic changes in pyroptosis following spinal cord injury and the identification of crucial molecular signatures through machine learning and single-cell sequencing. — PubMed · 2024 · Journal Article
- Falcarindiol improves functional recovery and alleviates neuroinflammation after spinal cord injury by inhibiting STAT/MAPK signaling pathways. — PubMed · 2024 · Journal Article
- Effect of Sakuranetin on Microglia-Mediated Neuroinflammation After Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Genetic deletion of the apoptosis associated speck like protein containing a card in LysM(+) macrophages attenuates spinal cord injury by regulating M1/M2 polarization through ASC-dependent inflammasome signaling axis. — PubMed · 2024 · Journal Article
- Heme Oxygenase-1 Overexpression Activates the IRF1/DRP1 Signaling Pathway to Promote M2-Type Polarization of Spinal Cord Microglia. — PubMed · 2024 · Journal Article
- Interleukin-3 Modulates Macrophage Phagocytic Activity and Promotes Spinal Cord Injury Repair. — PubMed · 2024 · Journal Article
- Microenvironment Self-Adaptive Nanomedicine Promotes Spinal Cord Repair by Suppressing Inflammation Cascade and Neural Apoptosis. — PubMed · 2024 · Journal Article
- Mirtazapine Improves Locomotor Activity and Attenuates Neuropathic Pain Following Spinal Cord Injury in Rats via Neuroinflammation Modulation. — PubMed · 2024 · Journal Article
- scRNA-Seq reveals age-dependent microglial evolution as a determinant of immune response following spinal cord injury. — PubMed · 2024 · Journal Article
- TGN-020 ameliorates motor dysfunction post-spinal cord injury via enhancing astrocyte autophagy and mitigating inflammation by activating AQP4/PPAR-γ/mTOR pathway. — PubMed · 2024 · Journal Article
- The Circadian Clock Gene Bmal1 Regulates Microglial Pyroptosis After Spinal Cord Injury via NF-κB/MMP9. — PubMed · 2024 · Journal Article
- Therapeutic potential of EVs loaded with CB2 receptor agonist in spinal cord injury via the Nrf2/HO-1 pathway. — PubMed · 2024 · Journal Article
- Induction of Neural Differentiation and Protection by a Novel Slow-Release Nanoparticle Estrogen Construct in a Rat Model of Spinal Cord Injury. — PubMed · 2024 · Journal Article
- A critical role for microglia in regulating metabolic homeostasis and neural repair after spinal cord injury. — PubMed · 2024 · Journal Article
- P2Y12-targeted modulation of microglial phenotypes: A novel therapeutic strategy for enhanced axonal regeneration post-spinal cord injury. — PubMed · 2024 · Journal Article
- Targeting resident astrocytes attenuates neuropathic pain after spinal cord injury. — PubMed · 2024 · Journal Article
- Cynarin inhibits microglia-induced pyroptosis and neuroinflammation via Nrf2/ROS/NLRP3 axis after spinal cord injury. — PubMed · 2024 · Journal Article
- Omega-3 polyunsaturated fatty acids alleviate endoplasmic reticulum stress-induced neuroinflammation by protecting against traumatic spinal cord injury through the histone deacetylase 3/ peroxisome proliferator-activated receptor-γ coactivator pathway. — PubMed · 2024 · Journal Article
- Regulation of microglia inflammation and oligodendrocyte demyelination by Engeletin via the TLR4/RRP9/NF-κB pathway after spinal cord injury. — PubMed · 2024 · Journal Article
- TRIM56 Modulates YBX1 Degradation to Ameliorate ZBP1-Mediated Neuronal PANoptosis in Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Curcumin/pEGCG-encapsulated nanoparticles enhance spinal cord injury recovery by regulating CD74 to alleviate oxidative stress and inflammation. — PubMed · 2024 · Journal Article
- In vivo spectrally unmixed multi-photon imaging of longitudinal axon-glia changes in injured spinal white matter. — PubMed · 2024 · Journal Article
- In vivo imaging in mouse spinal cord reveals that microglia prevent degeneration of injured axons. — PubMed · 2024 · Journal Article
- Heterophyllin B enhances transcription factor EB-mediated autophagy and alleviates pyroptosis and oxidative stress after spinal cord injury. — PubMed · 2024 · Journal Article
- An oil-in-gel type of organohydrogel loaded with methylprednisolone for the treatment of secondary injuries following spinal cord traumas. — PubMed · 2024 · Journal Article
- Astrocyte-derived lipocalin 2 promotes inflammation and scarring after spinal cord injury by activating SMAD in mice. — PubMed · 2024 · Journal Article
- Clickable Granular Hydrogel Scaffolds for Delivery of Neural Progenitor Cells to Sites of Spinal Cord Injury. — PubMed · 2024 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 3 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851312 · this programme has 48 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 29 · this programme has 3219 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroinflammation" OR "microglia" OR "immune response") - Crossref
spinal cord injury neuroinflammation microglia - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neurogenic Inflammation"[MeSH Terms] OR "Microglia"[MeSH Terms] OR "Neuroimmunomodulation"[MeSH Terms] OR "neuroinflammation"[Title/Abstract] OR "microglia"[Title/Abstract] OR "immune response"[Title/Abstract])