A subject this map covers
Inflammation and immune response
What belongs here
What immune cells do after injury — both as damage and as a necessary part of healing.
What does not belong here, however close it looks
Infection and sepsis are clinical management, a separate subject.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 769 records · 1981–2027
- Indexed as work in animals: 1704 records · 1975–2027
- Indexed as laboratory work: 73 records · 2001–2026
- The source has not said who or what was studied: 639 records · 1998–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3185 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Orchestrating Scarless Spinal Cord Repair: Dynamic Glial-Immune Interplay and Biomaterial Support. — PubMed · 2026 · Journal Article
- Targeting Neuroinflammatory and Regenerative Pathways with Monoclonal Antibodies in Spinal Cord Injury: A Bibliometric Analysis. — PubMed · 2026 · Journal Article
- Therapeutic Mechanisms of Stem Cell-Derived Exosomes for Neurological Disorders: An Overview. — PubMed · 2026 · Journal Article
- Phase-dependent efficacy of intravenous amniotic mesenchymal stem cells in a rat spinal cord injury model. — PubMed · 2026 · Journal Article
- The Pivotal Roles of Macrophages and Microglia in Mesenchymal Stromal/Stem Cell-Derived Small Extracellular Vesicle-Mediated Tissue Repair After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Enhanced MIF/CD74 axis activity shapes B cell functioning following traumatic spinal cord injury. — PubMed · 2026 · Journal Article
- The Dual Role of Connexins in Stroke, Neurotrauma, Neurodegenerative and Psychiatric Disorders: A Global Systematic Review. — PubMed · 2026 · Journal Article
- Neurosurgery as an immune anchor point: a translational framework for perioperative immunoengineering. — PubMed · 2026 · Journal Article
- Spatiotemporal Delivery of a Cell-Free DNA Scavenger for Detoxification and Neural Repair after Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Insights into the role of the mechanosensitive Piezo1 channel and signaling mechanisms in CNS functions and diseases. — PubMed · 2026 · Journal Article
- miR-107-5p mitigates spinal cord injury by targeting the PLOD2/HK2 axis. — PubMed · 2026 · Journal Article
- The Hypothesis of Myelinodegeneration as an Initial Risk of Neuropathic Pain. — PubMed · 2026 · Journal Article
- Injectable hydrogel-based localized delivery of IDO-galectin-3 mitigates neuroinflammation and promotes neuronal sparing after spinal cord contusion in rats. — PubMed · 2026 · Journal Article
- Decoding TREM2 Signaling Pathways: Linking Macrophage Glycolysis to Inflammatory Diseases in the CNS. — PubMed · 2026 · Journal Article
- Phagocytosis and neuroinflammation: orchestrating central nervous system homeostasis, repair, and the resolution of inflammation. — PubMed · 2026 · Journal Article
- Recent advances in the application of engineered extracellular vesicles from mesenchymal stem cells for traumatic central nervous system. — PubMed · 2026 · Journal Article
- Fascin-1 Limits Secondary Damage by Preventing Oxidative‑Stress‑Induced Microglial Death After Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Neural Stem Cells and Inflammation Modulation in Preclinical Spinal Cord Injury: A Systematic Review. — PubMed · 2026 · Journal Article
- Systemic Interleukin-4 Application Promotes Functional Recovery and Reprograms Neuroinflammatory and Molecular Responses after Spinal Cord Injury in Rats. — PubMed · 2026 · Journal Article
- Neurobiology of TRPM channels in pain processing: Current advances and future directions. — PubMed · 2026 · Journal Article
- The main signaling pathways determining the microglia responses in spinal cord injury: Potential effectors among known pharmaceuticals. — PubMed · 2026 · Journal Article
- Mechanisms and Clinical Application Progress of Exercise in the Treatment of Neuropathic Pain. — PubMed · 2026 · Journal Article
- Nanomaterial-based therapeutic strategies for spinal cord injury repair: harnessing multifunctionality to overcome pathophysiological challenges. — PubMed · 2026 · Journal Article
- The effects of electrical stimulation on neurons and glia of the central nervous system. — PubMed · 2026 · Journal Article
- Immune responses in the microenvironment after spinal-cord injury: A bibliometric study from 2005 to 2024. — PubMed · 2026 · Journal Article
- A Review of The Place of Adipose-Derived Stem Cells among Stem Cell Applications in Neurodegenerative Diseases. — PubMed · 2026 · Journal Article
- Identification and Verification of Mitochondria-Related Diagnostic Markers of Spinal Cord Injury by WGCNA and Machine Learning. — PubMed · 2026 · Journal Article
- Lesion-remote astrocytes govern microglia-mediated white matter repair. — PubMed · 2026 · Journal Article
- M5C-methylated EDIL3 attenuates spinal cord ischemia-reperfusion injury by suppressing neutrophil extracellular trap formation. — PubMed · 2026 · Journal Article
- The Second Hit Hypothesis in Animal and Human Dystonia: The Role of Peripheral Nerve Trauma and Spinal Cord Injury. — PubMed · 2026 · Journal Article
- Upregulation of miR-502-5p in traumatic spinal cord injury modulates neuroinflammation and oxidative stress by targeting FBXO28. — PubMed · 2025 · Journal Article
- Mesenchymal Stem Cell-Derived Exosomes: A Promising Therapeutic Strategy for Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Beyond Fuel: Exercise-Induced Lactate as a Metabolic-Epigenetic Regulator in Central Nervous System Health and Disease. — PubMed · 2025 · Journal Article
- Regulatory T cells promote microglia-mediated synapse engulfment and functional recovery via the OPN-CD74 axis after spinal cord injury in mice. — PubMed · 2025 · Journal Article
- Inorganic, Synthetic, Natural, and Innovative Hybrid Hydrogen Sulfide Donors and Inhibitors of Its Biosynthesis in the Treatment of Central and Peripheral Nervous System Injuries: A Systematic Analytical Review. — PubMed · 2025 · Journal Article
- Neutrophil extracellular traps released by CD177(+) neutrophils aggravated inflammation and neuronal impairment post-SCI. — PubMed · 2025 · Journal Article
- Bi-directional communication between regulatory T cells and microglia promotes recovery from spinal cord injury. — PubMed · 2025 · Journal Article
- The forgotten inflammasomes: AIM2, NLRP1, and NLRC4 in spinal cord injury and neuroinflammation. — PubMed · 2025 · Journal Article
- The role of polarization dynamics in macrophages and microglia on the inflammatory microenvironment of spinal cord injury. — PubMed · 2025 · Journal Article
- Biomimetic Nanoplatform Based on the Neutrophil Membrane for Targeted Therapy of Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Circulating microRNA Profiles in Acute Spinal Cord Injury: Evidence for Distinct Plasma Signatures Compared with Polytrauma Patients. — PubMed · 2025 · Journal Article
- Targeted delivery of the GPX4 activator via HUCMSC-derived exosomes inhibits ferroptosis in spinal cord injury. — PubMed · 2025 · Journal Article
- Enhancing spinal cord injury recovery with functional liposomal nanomedicine: A neuroprotective and anti-inflammatory approach. — PubMed · 2025 · Journal Article
- Spinal Cord Injury 2.0: Bridging the Gap Between Neurobiology, Technology, and Hope in the Era of Precision Medicine. — PubMed · 2025 · Journal Article
- Galanin regulates M1/M2 polarization of microglia after spinal cord injury through TRPV1/Ca2+/CaMKII/NRF2 signaling pathway. — PubMed · 2025 · Journal Article
- Hormonal regulatory networks in spinal cord injury: mechanistic insights, crosstalk, and therapeutic innovations. — PubMed · 2025 · Journal Article
- Suppression of Glial Activation in Tau Transgenic Mice Through Inhibition of CRMP2 Phosphorylation: a Morphometric Analysis. — PubMed · 2025 · Journal Article
- GelMA Hydrogel Encapsulating iPSC-Derived Human Spinal Cord Organoids Enhances Neural Regeneration and Restores Motor Function in Rat Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Recent advances in potential mechanisms of epidural spinal cord stimulation for movement disorders. — PubMed · 2025 · Journal Article
- The neuroinflammatory triumvirate: NF-κB, NLRP3, and mTOR in spinal cord injury. — PubMed · 2025 · Journal Article
- Is TREM2 a Stretch: Implications of TREM2 Along Spinal Cord Circuits in Health, Aging, Injury, and Disease. — PubMed · 2025 · Journal Article
- CRISPR and Artificial Intelligence in Neuroregeneration: Closed-Loop Strategies for Precision Medicine, Spinal Cord Repair, and Adaptive Neuro-Oncology. — PubMed · 2025 · Journal Article
- Calpains at the Crossroads of Spinal Cord Physiology, Plasticity, and Pathology. — PubMed · 2025 · Journal Article
- How Advanced Are Exosomes as Cell-Free Therapeutics for Spinal Cord Injury? — PubMed · 2025 · Journal Article
- Selenized neural stem cell-derived exosomes: A neotype therapeutic agent for traumatic injuries of the central nervous system. — PubMed · 2025 · Journal Article
- Multidimensional Engineering of Extracellular Vesicles for Targeted Delivery and Microglial Reprograming in Spinal Cord Injury Repair. — PubMed · 2025 · Journal Article
- A review of bigels for neurotrauma therapeutics: Structural insights for tissue microenvironment alignment. — PubMed · 2025 · Journal Article
- Bibliometric Mapping of Research Trends and Hotspots of Microglia in Spinal Cord Injury (2000-2024). — PubMed · 2025 · Journal Article
- Guttmann NeuroRecovery - Viability, Safety, and Efficacy of Intrathecal Wharton's Jelly Mesenchymal Stem Cells and Transcutaneous Spinal Cord Stimulation in Chronic Spinal Cord Injury Rehabilitation — ClinicalTrials.gov · 2025 · Interventional · Not Yet Recruiting
- Relaxin-2 Ameliorates Spinal Cord Injury by Inhibiting Microglia Activation. — PubMed · 2025 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 3 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851312 · this programme has 48 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 29 · this programme has 3219 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroinflammation" OR "microglia" OR "immune response") - Crossref
spinal cord injury neuroinflammation microglia - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neurogenic Inflammation"[MeSH Terms] OR "Microglia"[MeSH Terms] OR "Neuroimmunomodulation"[MeSH Terms] OR "neuroinflammation"[Title/Abstract] OR "microglia"[Title/Abstract] OR "immune response"[Title/Abstract])