A subject this map covers
Inflammation and immune response
What belongs here
What immune cells do after injury — both as damage and as a necessary part of healing.
What does not belong here, however close it looks
Infection and sepsis are clinical management, a separate subject.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 769 records · 1981–2027
- Indexed as work in animals: 1704 records · 1975–2027
- Indexed as laboratory work: 73 records · 2001–2026
- The source has not said who or what was studied: 639 records · 1998–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3185 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Umbilical cord-derived exosomes alleviate spinal cord injury by regulating microglial polarization through miR-340-5p-mediated modulation of the JAK/STAT3 signaling pathway. — PubMed · 2025 · Journal Article
- Human iPSC-derived spinal neural progenitors enhance sensorimotor recovery in spinal cord-injured NOD-SCID mice via differentiation and microenvironment regulation. — PubMed · 2025 · Journal Article
- Mechanistic insights into the therapeutic potential of β-elemene on glioma and other central nervous system diseases. — PubMed · 2025 · Journal Article
- Microglial pyroptosis as a therapeutic target after traumatic spinal cord injury: current progress and future directions. — PubMed · 2025 · Journal Article
- F-box/LRR-repeat protein 12 reorchestrated microglia to inhibit scarring and achieve adult spinal cord injury repair. — PubMed · 2025 · Journal Article
- Evolving insights on the role of microglia in neuroinflammation, plasticity, and regeneration of the injured spinal cord. — PubMed · 2025 · Journal Article
- A Review of Pathophysiology, Molecular Mechanisms, and Omics Approaches of Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Exosomes Derived from Tanshinone IIA-Pretreated Umbilical Cord Mesenchymal Stem Cells Repair Traumatic Spinal Cord Injury by miR-223-5p/USP8/NLRP3 Axis. — PubMed · 2025 · Journal Article
- Bibliometric Analysis of Exosome Research in Spinal Cord Injury (2000-May 2024). Trends, Collaborations, and Emerging Insights. — PubMed · 2025 · Journal Article
- CircGTF2H2C Regulates NLRP3 Dephosphorylation via Modulating PTPN11 Expression in Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Exploring Innovative Approaches for Managing Spinal Cord Injury: A Comprehensive Review of Promising Probiotics and Postbiotics. — PubMed · 2025 · Journal Article
- Neuroprotective Potential of Curcumin in Neurodegenerative Diseases: Clinical Insights Into Cellular and Molecular Signaling Pathways. — PubMed · 2025 · Journal Article
- Recombinant human DNase treatment mitigates extracellular trap mediated damage and improves long-term recovery after spinal cord injury in male mice. — PubMed · 2025 · Journal Article
- Targeting JAK/STAT signaling pathway by curcumin: implications for spinal cord injury neuroprotection. — PubMed · 2025 · Journal Article
- Spinal Cord Injury Remyelination: Pathways to Therapies. — PubMed · 2025 · Journal Article
- Metabolic reprogramming through histone lactylation in microglia and macrophages recruits CD8(+) T lymphocytes and aggravates spinal cord injury. — PubMed · 2025 · Journal Article
- Precision Recovery After Spinal Cord Injury: Integrating CRISPR Technologies, AI-Driven Therapeutics, Single-Cell Omics, and System Neuroregeneration. — PubMed · 2025 · Journal Article
- Identification and experimental validation of BMX as a crucial PANoptosis‑related gene for immune response in Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Spinal Cord Injury and Ageing: The Role of Chronic Neuroinflammation. — PubMed · 2025 · Journal Article
- Chrysin's anti-inflammatory action in the central nervous system: A scoping review and an evidence-gap mapping of its mechanisms. — PubMed · 2025 · Journal Article
- Advanced Therapeutic Approaches Based on Small Extracellular Vehicles (sEVs) For the Regeneration of Spinal Cord Injuries. — PubMed · 2025 · Journal Article
- Exosome-based therapeutics: Advancing drug delivery for neurodegenerative diseases. — PubMed · 2025 · Journal Article
- Multi-omics analysis identified and confirmed TNF-α as a key initiator of the inflammatory response following spinal cord injury. — PubMed · 2025 · Journal Article
- Nitric oxide synthases: A delicate dance between bone regeneration and neuronal birth. — PubMed · 2025 · Journal Article
- The role of alarmins in neuroinflammation following spinal cord injury: A systematic review of the literature. — PubMed · 2025 · Journal Article
- The Role of Cardiolipin in Brain Bioenergetics, Neuroinflammation, and Neurodegeneration. — PubMed · 2025 · Journal Article
- Unlocking the neuroprotective potential of peptide nucleic acids 5 (PNA5) in neurological diseases: molecular mechanisms to therapeutic approaches. — PubMed · 2025 · Journal Article
- Rewiring the Spine-Cutting-Edge Stem Cell Therapies for Spinal Cord Repair. — PubMed · 2025 · Journal Article
- Autophagy modulation by hADSCs and green light therapy alleviates inflammation and promotes functional recovery after spinal cord injury. — PubMed · 2025 · Journal Article
- Plexin B2 in physiology and pathophysiology of the central nervous system. — PubMed · 2025 · Journal Article
- Comparative study of subacute combined degeneration of the spinal cord due to nitrous oxide abuse and vitamin B12 deficiency. — PubMed · 2025 · Journal Article
- Administration of hypoxic pretreated adipose-derived mesenchymal stem cell exosomes promotes spinal cord repair after injury via delivery of circ-Astn1 and activation of autophagy. — PubMed · 2025 · Journal Article
- Advances in the Treatment of Spinal Cord Injury with Nanozymes. — PubMed · 2025 · Journal Article
- Metabolic Reprogramming in Spinal Cord Injury and Analysis of Potential Therapeutic Targets. — PubMed · 2025 · Journal Article
- Nanoparticle delivery of CD68 siRNA inhibits neuroimmune responses by inhibiting activation of M1 macrophages. — PubMed · 2025 · Journal Article
- Astrocytic Ryk signaling coordinates scarring and wound healing after spinal cord injury. — PubMed · 2025 · Journal Article
- Flavonoids in the regulation of microglial-mediated neuroinflammation; focus on fisetin, rutin, and quercetin. — PubMed · 2025 · Journal Article
- VEGF secreted by human dental pulp stem cell promotes spinal cord injury repair by inhibiting microglial pyroptosis through the PI3K/AKT pathway. — PubMed · 2025 · Journal Article
- Human Amniotic Epithelial Stem Cells Promote Functional Recovery After Spinal Cord Injury In Rats By Regulating The Polarization Of Macrophages. — PubMed · 2025 · Journal Article
- Mechanisms and Therapeutic Prospects of Microglia-Astrocyte Interactions in Neuropathic Pain Following Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Repulsive Guidance Molecule-A as a Therapeutic Target Across Neurological Disorders: An Update. — PubMed · 2025 · Journal Article
- Local delivery of mesenchymal stem cell-extruded nanovesicles through a bio-responsive scaffold for acute spinal cord injury treatment. — PubMed · 2025 · Journal Article
- Pyroptosis: candidate key targets for mesenchymal stem cell-derived exosomes for the treatment of bone-related diseases. — PubMed · 2025 · Journal Article
- Focusing on Formyl Peptide Receptors after Traumatic Spinal Cord Injury: from Immune Response to Neurogenesis. — PubMed · 2025 · Journal Article
- Multi-omics uncovers immune-modulatory molecules in plasma contributing to resistance exercise-ameliorated locomotor disability after incomplete spinal cord injury. — PubMed · 2025 · Journal Article
- Conventional type 1 dendritic cells in the lymph nodes aggravate neuroinflammation after spinal cord injury by promoting CD8(+) T cell expansion. — PubMed · 2025 · Journal Article
- BoNT/Action beyond neurons. — PubMed · 2025 · Journal Article
- Mechanism of effect and therapeutic potential of NLRP3 inflammasome in spinal cord injury. — PubMed · 2025 · Journal Article
- Sirtuin1 in Spinal Cord Injury: Regulatory Mechanisms, Microenvironment Remodeling and Therapeutic Potential. — PubMed · 2025 · Journal Article
- Interaction of microglia with the microenvironment in spinal cord injury. — PubMed · 2025 · Journal Article
- Integrated bioinformatics analysis identified cuproptosis-related hub gene Mpeg1 as potential biomarker in spinal cord injury. — PubMed · 2025 · Journal Article
- Ferroptosis-related genes participate in the microglia-induced neuroinflammation of spinal cord injury via NF-κB signaling: evidence from integrated single-cell and spatial transcriptomic analysis. — PubMed · 2025 · Journal Article
- Spatial distribution-based progression of spinal cord injury pathology: a key role for neuroimmune cells. — PubMed · 2025 · Journal Article
- Transcriptomic and Functional Landscape of Adult Human Spinal Cord NSPCs Compared to iPSC-Derived Neural Progenitor Cells. — PubMed · 2025 · Journal Article
- Nrf2 Inhibits GAPDH/Siah1 Axis to Reduce Inflammatory Reactions and Proliferation of Microglia After Simulating Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Therapeutic Potential of Mesenchymal Stem Cell-Derived Exosomes in Spinal Cord Injury. — PubMed · 2025 · Journal Article
- Unraveling the complexity of microglial responses in traumatic brain and spinal cord injury. — PubMed · 2025 · Journal Article
- Histological effects of combined therapy involving scar resection, decellularized scaffolds, and human iPSC-NS/PCs transplantation in chronic complete spinal cord injury. — PubMed · 2024 · Journal Article
- Macrophages dying from ferroptosis promote microglia-mediated inflammatory responses during spinal cord injury. — PubMed · 2024 · Journal Article
- Regulation of dynamic spatiotemporal inflammation by nanomaterials in spinal cord injury. — PubMed · 2024 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 3 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851312 · this programme has 48 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 29 · this programme has 3219 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroinflammation" OR "microglia" OR "immune response") - Crossref
spinal cord injury neuroinflammation microglia - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neurogenic Inflammation"[MeSH Terms] OR "Microglia"[MeSH Terms] OR "Neuroimmunomodulation"[MeSH Terms] OR "neuroinflammation"[Title/Abstract] OR "microglia"[Title/Abstract] OR "immune response"[Title/Abstract])