A subject this map covers
Inflammation and immune response
What belongs here
What immune cells do after injury — both as damage and as a necessary part of healing.
What does not belong here, however close it looks
Infection and sepsis are clinical management, a separate subject.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 769 records · 1981–2027
- Indexed as work in animals: 1704 records · 1975–2027
- Indexed as laboratory work: 73 records · 2001–2026
- The source has not said who or what was studied: 639 records · 1998–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3185 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Differential expression of genes involved in the chronic response to intracortical microelectrodes. — PubMed · 2023 · Journal Article
- Knockout of microglial Hv1 proton channel reduces neurotoxic A1 astrocytes and neuronal damage via the ROS/STAT3 pathway after spinal cord injury. — PubMed · 2023 · Journal Article
- Mesenchymal stem cells (MSCs) and MSC-derived exosomes in animal models of central nervous system diseases: Targeting the NLRP3 inflammasome. — PubMed · 2023 · Journal Article
- Neuroprotective role of calreticulin after spinal cord injury in mice. — PubMed · 2023 · Journal Article
- Phosphodiesterase 4 Inhibitor Roflupram Suppresses Inflammatory Responses Using Reducing Inflammasome in Microglia After Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Protective effect of TNIP2 on the inflammatory response of microglia after spinal cord injury in rats. — PubMed · 2023 · Journal Article
- Single-Cell Sequencing Reveals the Optimal Time Window for Anti-Inflammatory Treatment in Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Unbiased multitissue transcriptomic analysis reveals complex neuroendocrine regulatory networks mediated by spinal cord injury-induced immunodeficiency. — PubMed · 2023 · Journal Article
- Rapid and Efficient Enrichment of Mouse Spinal Cord Microglia. — PubMed · 2023 · Journal Article
- ScRNA analysis and ferroptosis-related ceRNA regulatory network investigation in microglia cells at different time points after spinal cord injury. — PubMed · 2023 · Journal Article
- In Situ Cross-Linkable Hyaluronic-Ferulic Acid Conjugate Containing Bucladesine Nanoparticles Promotes Neural Regeneration after Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Tofacitinib Promotes Functional Recovery after Spinal Cord Injury by Regulating Microglial Polarization via JAK/STAT Signaling Pathway. — PubMed · 2023 · Journal Article
- Analysis of gene expression profiles and experimental validations of a rat chronic cervical cord compression model. — PubMed · 2023 · Journal Article
- Curcumin-activated Olfactory Ensheathing Cells Improve Functional Recovery After Spinal Cord Injury by Modulating Microglia Polarization Through APOE/TREM2/NF-κB Signaling Pathway. — PubMed · 2023 · Journal Article
- Organization of collagen fibers and tissue hardening: Markers of fibrotic scarring after spinal cord injury in mice revealed by multiphoton-atomic force microscopy imaging. — PubMed · 2023 · Journal Article
- Rolipram-loaded PgP nanoparticle reduces secondary injury and enhances motor function recovery in a rat moderate contusion SCI model. — PubMed · 2023 · Journal Article
- Sexually dimorphic extracellular vesicle responses after chronic spinal cord injury are associated with neuroinflammation and neurodegeneration in the aged brain. — PubMed · 2023 · Journal Article
- Loganin reduces neuroinflammation and promotes functional recovery after spinal cord injury through inhibiting NF-κB/NLRP3 signalling. — PubMed · 2023 · Journal Article
- Single-cell analysis reveals region-heterogeneous responses in rhesus monkey spinal cord with complete injury. — PubMed · 2023 · Journal Article
- Celsr2-mediated morphological polarization and functional phenotype of reactive astrocytes in neural repair. — PubMed · 2023 · Journal Article
- Histone Deacetylase 3 Inhibition Ameliorates Microglia-Mediated Neuro-Inflammation Via the SIRT1/Nrf2 Pathway After Traumatic Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Inhibition of TANK-binding kinase1 attenuates the astrocyte-mediated neuroinflammatory response through YAP signaling after spinal cord injury. — PubMed · 2023 · Journal Article
- Microneedle/CD-MOF-mediated transdural controlled release of methylprednisolone sodium succinate after spinal cord injury. — PubMed · 2023 · Journal Article
- Neuron-Derived Exosomes Promote the Recovery of Spinal Cord Injury by Modulating Nerve Cells in the Cellular Microenvironment of the Lesion Area. — PubMed · 2023 · Journal Article
- Pre-treatment of rapamycin transformed M2 microglia alleviates traumatic cervical spinal cord injury via AIM2 signaling pathway in vitro and in vivo. — PubMed · 2023 · Journal Article
- Regulatory T cells promote functional recovery after spinal cord injury by alleviating microglia inflammation via STAT3 inhibition. — PubMed · 2023 · Journal Article
- Spinal cord injury-activated C/EBPβ-AEP axis mediates cognitive impairment through APP C586/Tau N368 fragments spreading. — PubMed · 2023 · Journal Article
- Systemic vascular photobiomodulation accelerates the recovery of motor activity in rats following spinal cord injury. — PubMed · 2023 · Journal Article
- Discovery of therapeutic targets for spinal cord injury based on molecular mechanisms of axon regeneration after conditioning lesion. — PubMed · 2023 · Journal Article
- Age-dependent immune and lymphatic responses after spinal cord injury. — PubMed · 2023 · Journal Article
- Suppression of microglial Ccl2 reduces neuropathic pain associated with chronic spinal compression. — PubMed · 2023 · Journal Article
- Aging and TNF induce premature senescence of astrocytes after spinal cord injury via regulating YAP expression. — PubMed · 2023 · Journal Article
- Role of the Voltage-Gated Proton Channel Hv1 in Nervous Systems. — PubMed · 2023 · Journal Article
- Zileuton Ameliorates Neuronal Ferroptosis and Functional Recovery After Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Ezetimibe attenuates functional impairment via inhibition of oxidative stress and inflammation in traumatic spinal cord injury. — PubMed · 2023 · Journal Article
- Distinct myeloid population phenotypes dependent on TREM2 expression levels shape the pathology of traumatic versus demyelinating CNS disorders. — PubMed · 2023 · Journal Article
- [Acetylcorynoline inhibits microglia activation by regulating EGFR/MAPK signaling to promote functional recovery of injured mouse spinal cord]. — PubMed · 2023 · English Abstract
- Open-Spaced Ridged Hydrogel Scaffolds Containing TiO(2)-Self-Assembled Monolayer of Phosphonates Promote Regeneration and Recovery Following Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Sodium houttuyfonate exerts its neuroprotection effect by inhibiting the M1 microglia polarization in a TLR4/NF-κB signal pathway. — PubMed · 2023 · Journal Article
- Acupuncture combined with moxibustion mitigates spinal cord injury-induced motor dysfunction in mice by NLRP3-IL-18 signaling pathway inhibition. — PubMed · 2023 · Journal Article
- An inhibitor of claudin-5 interactions, M01, alleviates neuroinflammation and vasogenic edema after blood-spinal cord barrier dysfunction. — PubMed · 2023 · Journal Article
- Cinepazide maleate promotes recovery from spinal cord injury by inhibiting inflammation and prolonging neuronal survival. — PubMed · 2023 · Journal Article
- SARM1 promotes the neuroinflammation and demyelination through IGFBP2/NF-κB pathway in experimental autoimmune encephalomyelitis mice. — PubMed · 2023 · Journal Article
- Therapeutic administration of mouse mast cell protease 6 improves functional recovery after traumatic spinal cord injury in mice by promoting remyelination and reducing glial scar formation. — PubMed · 2023 · Journal Article
- Lipocalin-2 Deficiency Diminishes Canonical NLRP3 Inflammasome Formation and IL-1β Production in the Subacute Phase of Spinal Cord Injury. — PubMed · 2023 · Journal Article
- "Combo" Multi-Target Pharmacological Therapy and New Formulations to Reduce Inflammation and Improve Endogenous Remyelination in Traumatic Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Acute Transcriptomic and Epigenetic Alterations at T12 After Rat T10 Spinal Cord Contusive Injury. — PubMed · 2023 · Journal Article
- Architecture-Engineered Electrospinning Cascade Regulates Spinal Microenvironment to Promote Nerve Regeneration. — PubMed · 2023 · Journal Article
- Hesperetin ameliorates spinal cord injury by inhibiting NLRP3 inflammasome activation and pyroptosis through enhancing Nrf2 signaling. — PubMed · 2023 · Journal Article
- Hydralazine plays an immunomodulation role of pro-regeneration in a mouse model of spinal cord injury. — PubMed · 2023 · Journal Article
- Inhibition of neuronal peroxisome proliferator-activated receptor-γ attenuates motor function improvement after spinal cord injury in rats. — PubMed · 2023 · Journal Article
- Targeting of MALT1 May Improve Functional Recovery and Attenuate Microglia M1 Polarization-Mediated Neuroinflammation During Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Analysis and verification of the circRNA regulatory network RNO_CIRCpedia_ 4214/RNO-miR-667-5p/Msr1 axis as a potential ceRNA promoting macrophage M2-like polarization in spinal cord injury. — PubMed · 2023 · Journal Article
- Adalimumab combined with erythropoietin improves recovery from spinal cord injury by suppressing microglial M1 polarization-mediated neural inflammation and apoptosis. — PubMed · 2023 · Journal Article
- Alpinetin inhibits neuroinflammation and neuronal apoptosis via targeting the JAK2/STAT3 signaling pathway in spinal cord injury. — PubMed · 2023 · Journal Article
- Mild inflammation impairs acute intermittent hypoxia-induced phrenic long-term facilitation by a spinal adenosine-dependent mechanism. — PubMed · 2023 · Journal Article
- PU.1 interaction with p50 promotes microglial-mediated inflammation in secondary spinal cord injury in SCI rats. — PubMed · 2023 · Journal Article
- Mouse Spinal Cord Vascular Transcriptome Analysis Identifies CD9 and MYLIP as Injury-Induced Players. — PubMed · 2023 · Journal Article
- Swimming training combined with fecal microbial transplantation protects motor functions in rats with spinal cord injury by improving the intestinal system. — PubMed · 2023 · Journal Article
- Differential effects of NOX2 and NOX4 inhibition after rodent spinal cord injury. — PubMed · 2023 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 3 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 851312 · accumulated records across collection walks 48 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 29 · accumulated records across collection walks 3219 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroinflammation" OR "microglia" OR "immune response") - Crossref
spinal cord injury neuroinflammation microglia - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neurogenic Inflammation"[MeSH Terms] OR "Microglia"[MeSH Terms] OR "Neuroimmunomodulation"[MeSH Terms] OR "neuroinflammation"[Title/Abstract] OR "microglia"[Title/Abstract] OR "immune response"[Title/Abstract])