A subject this map covers
Inflammation and immune response
What belongs here
What immune cells do after injury — both as damage and as a necessary part of healing.
What does not belong here, however close it looks
Infection and sepsis are clinical management, a separate subject.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 769 records · 1981–2027
- Indexed as work in animals: 1704 records · 1975–2027
- Indexed as laboratory work: 73 records · 2001–2026
- The source has not said who or what was studied: 639 records · 1998–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3185 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Composite Fibrin and Carbon Microfibre Implant to Modulate Postraumatic Inflammation after Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Acute baclofen administration promotes functional recovery after spinal cord injury. — PubMed · 2023 · Journal Article
- Conditioned medium from bone marrow mesenchymal stem cells relieves spinal cord injury through suppression of Gal-3/NLRP3 and M1 microglia/macrophage polarization. — PubMed · 2023 · Journal Article
- Eumelanin decorated poly(lactic acid) electrospun substrates as a new strategy for spinal cord injury treatment. — PubMed · 2023 · Journal Article
- Phosphoglycerate mutase 5 facilitates mitochondrial dysfunction and neuroinflammation in spinal tissues after spinal cord injury. — PubMed · 2023 · Journal Article
- Mesenchymal stem cells in the treatment of spinal cord injury: Mechanisms, current advances and future challenges. — PubMed · 2023 · Journal Article
- The polarization of microglia and infiltrated macrophages in the injured mice spinal cords: a dynamic analysis. — PubMed · 2023 · Journal Article
- Transplantation of A2 type astrocytes promotes neural repair and remyelination after spinal cord injury. — PubMed · 2023 · Video-Audio Media
- BDNF-induced phrenic motor facilitation shifts from PKCθ to ERK dependence with mild systemic inflammation. — PubMed · 2023 · Journal Article
- Extracellular traps formation following cervical spinal cord injury. — PubMed · 2023 · Journal Article
- Spatiotemporal Dynamics of the Molecular Expression Pattern and Intercellular Interactions in the Glial Scar Response to Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Tetramethylpyrazine and Astragaloside IV have synergistic effects against spinal cord injury-induced neuropathic pain via the OIP5-AS1/miR-34a/Sirt1/NF-κB axis. — PubMed · 2023 · Journal Article
- The aOECs Facilitate the Neuronal Differentiation of Neural Stem Cells in the Inflammatory Microenvironment Through Up-Regulation of Bioactive Factors and Activation of Wnt3/β-Catenin Pathway. — PubMed · 2023 · Journal Article
- Schwann cell-derived exosomes containing MFG-E8 modify macrophage/microglial polarization for attenuating inflammation via the SOCS3/STAT3 pathway after spinal cord injury. — PubMed · 2023 · Journal Article
- Combination of single-cell and bulk RNA seq reveals the immune infiltration landscape and targeted therapeutic drugs in spinal cord injury. — PubMed · 2023 · Journal Article
- Transient Reflexive Pain Responses and Chronic Affective Nonreflexive Pain Responses Associated with Neuroinflammation Processes in Both Spinal and Supraspinal Structures in Spinal Cord-Injured Female Mice. — PubMed · 2023 · Journal Article
- Direct implantation of hair-follicle-associated pluripotent (HAP) stem cells repairs intracerebral hemorrhage and reduces neuroinflammation in mouse model. — PubMed · 2023 · Journal Article
- Tocilizumab promotes repair of spinal cord injury by facilitating the restoration of tight junctions between vascular endothelial cells. — PubMed · 2023 · Journal Article
- 3D Gelatin Microsphere Scaffolds Promote Functional Recovery after Spinal Cord Hemisection in Rats. — PubMed · 2023 · Journal Article
- Adipose-derived mesenchymal stem cell exosomes ameliorate spinal cord injury in rats by activating the Nrf2/HO-1 pathway and regulating microglial polarization. — PubMed · 2023 · Journal Article
- Dopamine inhibits pyroptosis and attenuates secondary damage after spinal cord injury in female mice. — PubMed · 2023 · Journal Article
- Equilibrative Nucleoside Transporter 1 is a Target to Modulate Neuroinflammation and Improve Functional Recovery in Mice with Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Intrathecal minocycline does not block the adverse effects of repeated, intravenous morphine administration on recovery of function after SCI. — PubMed · 2023 · Journal Article
- Multifunctional hydrogel modulates the immune microenvironment to improve allogeneic spinal cord tissue survival for complete spinal cord injury repair. — PubMed · 2023 · Journal Article
- Perlecan Improves Blood Spinal Cord Barrier Repair Through the Integrin β1/ROCK/MLC Pathway After Spinal Cord Injury. — PubMed · 2023 · Journal Article
- Role of Transcription Factor Nrf2 in Pyroptosis in Spinal Cord Injury by Regulating GSDMD. — PubMed · 2023 · Journal Article
- Spinal cord injury induced exacerbation of Alzheimer's disease like pathophysiology is reduced by topical application of nanowired cerebrolysin with monoclonal antibodies to amyloid beta peptide, p-tau and tumor necrosis factor alpha. — PubMed · 2023 · Journal Article
- Targeting the AKT/mTOR/p70S6K Pathway for Oligodendrocyte Differentiation and Myelin Regeneration in Neurological Disorders. — PubMed · 2023 · Journal Article
- Taxifolin attenuates neuroinflammation and microglial pyroptosis via the PI3K/Akt signaling pathway after spinal cord injury. — PubMed · 2023 · Journal Article
- Treg cell-derived exosomes miR-709 attenuates microglia pyroptosis and promotes motor function recovery after spinal cord injury. — PubMed · 2022 · Journal Article
- 5-Fluorouracil reduces the fibrotic scar via inhibiting matrix metalloproteinase 9 and stabilizing microtubules after spinal cord injury. — PubMed · 2022 · Journal Article
- IL-12p40 promotes secondary damage and functional impairment after spinal cord contusional injury. — PubMed · 2022 · Journal Article
- Intermittent Hypoxia Differentially Regulates Adenosine Receptors in Phrenic Motor Neurons with Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Single cell profiling of CD45(+) spinal cord cells reveals microglial and B cell heterogeneity and crosstalk following spinal cord injury. — PubMed · 2022 · Journal Article
- Bone Marrow Mesenchymal Stem Cell Exosome Attenuates Inflammasome-Related Pyroptosis via Delivering circ_003564 to Improve the Recovery of Spinal Cord Injury. — PubMed · 2022 · Journal Article
- The protective effects of nesfatin-1 in neurological dysfunction after spinal cord injury by inhibiting neuroinflammation. — PubMed · 2022 · Journal Article
- Coexistence of chronic hyperalgesia and multilevel neuroinflammatory responses after experimental SCI: a systematic approach to profiling neuropathic pain. — PubMed · 2022 · Journal Article
- Morphine-induced changes in the function of microglia and macrophages after acute spinal cord injury. — PubMed · 2022 · Journal Article
- The alarmin interleukin-1α triggers secondary degeneration through reactive astrocytes and endothelium after spinal cord injury. — PubMed · 2022 · Journal Article
- Aucubin promoted neuron functional recovery by suppressing inflammation and neuronal apoptosis in a spinal cord injury model. — PubMed · 2022 · Journal Article
- Electroacupuncture ameliorates neuroinflammation in animal models. — PubMed · 2022 · Journal Article
- Forsythoside B attenuates neuro-inflammation and neuronal apoptosis by inhibition of NF-κB and p38-MAPK signaling pathways through activating Nrf2 post spinal cord injury. — PubMed · 2022 · Journal Article
- Neuropathology of distinct diaphragm areas following mid-cervical spinal cord contusion in the rat. — PubMed · 2022 · Journal Article
- Topotecan Reduces Neuron Death after Spinal Cord Injury by Suppressing Caspase-1-Dependent Pyroptosis. — PubMed · 2022 · Journal Article
- Ubiquitin ligase Triad1 promotes neurite outgrowth by inhibiting MDM2-mediated ubiquitination of the neuroprotective factor pleiotrophin. — PubMed · 2022 · Journal Article
- Cannabinoid receptor-2 attenuates neuroinflammation by promoting autophagy-mediated degradation of the NLRP3 inflammasome post spinal cord injury. — PubMed · 2022 · Journal Article
- Single-cell RNA sequencing reveals the role of immune-related autophagy in spinal cord injury in rats. — PubMed · 2022 · Journal Article
- Melatonin Attenuates Spinal Cord Injury in Mice by Activating the Nrf2/ARE Signaling Pathway to Inhibit the NLRP3 Inflammasome. — PubMed · 2022 · Journal Article
- Polyphenolic grape stalk and coffee extracts attenuate spinal cord injury-induced neuropathic pain development in ICR-CD1 female mice. — PubMed · 2022 · Journal Article
- Genetic deletion of the glucocorticoid receptor in Cx(3)cr1(+) myeloid cells is neuroprotective and improves motor recovery after spinal cord injury. — PubMed · 2022 · Journal Article
- lncRNA MEG3 restrained the M1 polarization of microglia in acute spinal cord injury through the HuR/A20/NF-κB axis. — PubMed · 2022 · Journal Article
- Neuroprotective effect of the Nrf2/ARE/miRNA145-5p signaling pathway in the early phase of spinal cord injury. — PubMed · 2022 · Journal Article
- Resveratrol suppresses microglial activation and promotes functional recovery of traumatic spinal cord via improving intestinal microbiota. — PubMed · 2022 · Journal Article
- Therapeutic Effects of Azithromycin on Spinal Cord Injury in Male Wistar Rats: A Role for Inflammatory Pathways. — PubMed · 2022 · Journal Article
- Inflammation: A Target for Treatment in Spinal Cord Injury. — PubMed · 2022 · Journal Article
- Identification of hub genes in the subacute spinal cord injury in rats. — PubMed · 2022 · Journal Article
- Bioinformatics analysis identified apolipoprotein E as a hub gene regulating neuroinflammation in macrophages and microglia following spinal cord injury. — PubMed · 2022 · Journal Article
- Excess intracellular ATP causes neuropathic pain following spinal cord injury. — PubMed · 2022 · Journal Article
- Inhibition of IL1R1 or CASP4 attenuates spinal cord injury through ameliorating NLRP3 inflammasome-induced pyroptosis. — PubMed · 2022 · Journal Article
- Grape Seed Proanthocyanidins Exert a Neuroprotective Effect by Regulating Microglial M1/M2 Polarisation in Rats with Spinal Cord Injury. — PubMed · 2022 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 3 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 851312 · accumulated records across collection walks 48 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 29 · accumulated records across collection walks 3219 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroinflammation" OR "microglia" OR "immune response") - Crossref
spinal cord injury neuroinflammation microglia - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neurogenic Inflammation"[MeSH Terms] OR "Microglia"[MeSH Terms] OR "Neuroimmunomodulation"[MeSH Terms] OR "neuroinflammation"[Title/Abstract] OR "microglia"[Title/Abstract] OR "immune response"[Title/Abstract])