A subject this map covers
Inflammation and immune response
What belongs here
What immune cells do after injury — both as damage and as a necessary part of healing.
What does not belong here, however close it looks
Infection and sepsis are clinical management, a separate subject.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 769 records · 1981–2027
- Indexed as work in animals: 1704 records · 1975–2027
- Indexed as laboratory work: 73 records · 2001–2026
- The source has not said who or what was studied: 639 records · 1998–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3185 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Resolvin D3 Promotes Inflammatory Resolution, Neuroprotection, and Functional Recovery After Spinal Cord Injury. — PubMed · 2021 · Journal Article
- Sumatriptan improves the locomotor activity and neuropathic pain by modulating neuroinflammation in rat model of spinal cord injury. — PubMed · 2021 · Journal Article
- The voltage-gated proton channel Hv1 plays a detrimental role in contusion spinal cord injury via extracellular acidosis-mediated neuroinflammation. — PubMed · 2021 · Journal Article
- Cryogen spray cooling mitigates inflammation and injury-induced CISD2 decline in rat spinal cord hemisection model. — PubMed · 2020 · Journal Article
- Meningeal lymphoid structures are activated under acute and chronic spinal cord pathologies. — PubMed · 2020 · Journal Article
- Combination of In Situ Lcn2 pRNA-RNAi Nanotherapeutics and iNSC Transplantation Ameliorates Experimental SCI in Mice. — PubMed · 2020 · Journal Article
- A new neutrophil subset promotes CNS neuron survival and axon regeneration. — PubMed · 2020 · Journal Article
- Electro-Acupuncture Inhibits p66Shc-Mediated Oxidative Stress to Facilitate Functional Recovery After Spinal Cord Injury. — PubMed · 2020 · Journal Article
- LncRNA SNHG1 attenuates neuropathic pain following spinal cord injury by regulating CDK4 level. — PubMed · 2020 · Journal Article
- Potential anti-neuroinflammatory NF-кB inhibitors based on 3,4-dihydronaphthalen-1(2H)-one derivatives. — PubMed · 2020 · Journal Article
- Salvianic Acid A Sodium Promotes the Recovery of Motor Function After Spinal Cord Injury in Rats by Reducing Microglia Inflammation through Regulating MIP2/Vdac1/Ndufa12 Signaling Axis. — PubMed · 2020 · Journal Article
- FBW7 protects against spinal cord injury by mitigating inflammation-associated neuronal apoptosis in mice. — PubMed · 2020 · Journal Article
- Serial Systemic Injections of Endotoxin (LPS) Elicit Neuroprotective Spinal Cord Microglia through IL-1-Dependent Cross Talk with Endothelial Cells. — PubMed · 2020 · Journal Article
- Integrated Bioinformatics Analysis of Hub Genes and Pathways Associated with a Compression Model of Spinal Cord Injury in Rats. — PubMed · 2020 · Journal Article
- Conditional Ablation of Myeloid TNF Improves Functional Outcome and Decreases Lesion Size after Spinal Cord Injury in Mice. — PubMed · 2020 · Journal Article
- Microglia-organized scar-free spinal cord repair in neonatal mice. — PubMed · 2020 · Journal Article
- microRNA-421-3p prevents inflammatory response in cerebral ischemia/reperfusion injury through targeting m6A Reader YTHDF1 to inhibit p65 mRNA translation. — PubMed · 2020 · Journal Article
- Red-Light (670 nm) Therapy Reduces Mechanical Sensitivity and Neuronal Cell Death, and Alters Glial Responses after Spinal Cord Injury in Rats. — PubMed · 2020 · Journal Article
- Time-dependent microglia and macrophages response after traumatic spinal cord injury in rat: a systematic review. — PubMed · 2020 · Journal Article
- Tripartite Motif Containing 52 Positively Regulates NF-κB Signaling by Promoting IκBα Ubiquitination in Lipopolysaccharide-Treated Microglial Cell Activation. — PubMed · 2020 · Journal Article
- The voltage-gated proton channel Hv1 contributes to neuronal injury and motor deficits in a mouse model of spinal cord injury. — PubMed · 2020 · Journal Article
- Distribution and polarization of microglia and macrophages at injured sites and the lumbar enlargement after spinal cord injury. — PubMed · 2020 · Journal Article
- Inhibiting HMGB1-RAGE axis prevents pro-inflammatory macrophages/microglia polarization and affords neuroprotection after spinal cord injury. — PubMed · 2020 · Journal Article
- Spinal cord injury can be relieved by the polysaccharides of Tricholoma matsutake by promoting axon regeneration and reducing neuroinflammation. — PubMed · 2020 · Journal Article
- Enolase inhibition alters metabolic hormones and inflammatory factors to promote neuroprotection in spinal cord injury. — PubMed · 2020 · Journal Article
- Injectable Hydrogel Containing Tauroursodeoxycholic Acid for Anti-neuroinflammatory Therapy After Spinal Cord Injury in Rats. — PubMed · 2020 · Journal Article
- Wild Bitter Melon Exerts Anti-Inflammatory Effects by Upregulating Injury-Attenuated CISD2 Expression following Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Resveratrol-primed exosomes strongly promote the recovery of motor function in SCI rats by activating autophagy and inhibiting apoptosis via the PI3K signaling pathway. — PubMed · 2020 · Journal Article
- Analysis of N- and O-Linked Glycosylation: Differential Glycosylation after Rat Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Deficiency of the microglial Hv1 proton channel attenuates neuronal pyroptosis and inhibits inflammatory reaction after spinal cord injury. — PubMed · 2020 · Journal Article
- Muscone suppresses inflammatory responses and neuronal damage in a rat model of cervical spondylotic myelopathy by regulating Drp1-dependent mitochondrial fission. — PubMed · 2020 · Journal Article
- The expressions of NLRP1, NLRP3, and AIM2 inflammasome complexes in the contusive spinal cord injury rat model and their responses to hormonal therapy. — PubMed · 2020 · Journal Article
- CRID3, a blocker of apoptosis associated speck like protein containing a card, ameliorates murine spinal cord injury by improving local immune microenvironment. — PubMed · 2020 · Journal Article
- Improved locomotor recovery after contusive spinal cord injury in Bmal1(-/-) mice is associated with protection of the blood spinal cord barrier. — PubMed · 2020 · Journal Article
- Chaperone-Mediated Autophagy after Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Exosomes from Long Noncoding RNA-Gm37494-ADSCs Repair Spinal Cord Injury via Shifting Microglial M1/M2 Polarization. — PubMed · 2020 · Journal Article
- FTY720 Attenuates Neuropathic Pain after Spinal Cord Injury by Decreasing Systemic and Local Inflammation in a Rat Spinal Cord Compression Model. — PubMed · 2020 · Journal Article
- Reactive astrocytes increase expression of proNGF in the mouse model of contused spinal cord injury. — PubMed · 2020 · Journal Article
- Neuron-derived exosomes-transmitted miR-124-3p protect traumatically injured spinal cord by suppressing the activation of neurotoxic microglia and astrocytes. — PubMed · 2020 · Journal Article
- Correlation between elevated inflammatory cytokines of spleen and spleen index in acute spinal cord injury. — PubMed · 2020 · Journal Article
- Depletion of microglia exacerbates injury and impairs function recovery after spinal cord injury in mice. — PubMed · 2020 · Journal Article
- Inhibition of leucine-rich repeats and calponin homology domain containing 1 accelerates microglia-mediated neuroinflammation in a rat traumatic spinal cord injury model. — PubMed · 2020 · Journal Article
- Excess administration of miR-340-5p ameliorates spinal cord injury-induced neuroinflammation and apoptosis by modulating the P38-MAPK signaling pathway. — PubMed · 2020 · Journal Article
- Hesperidin methyl chalcone alleviates spinal tuberculosis in New Zealand white rabbits by suppressing immune responses. — PubMed · 2020 · Journal Article
- Intravenous delivery of microRNA-133b along with Argonaute-2 enhances spinal cord recovery following cervical contusion in mice. — PubMed · 2020 · Journal Article
- Molecular and histologic outcomes following spinal cord injury in spiny mice, Acomys cahirinus. — PubMed · 2020 · Journal Article
- Microglia: Multiple states and multiple roles in the normal and diseased brain and spinal cord. — PubMed · 2020 · Editorial
- Adipose mesenchymal stem cell transplantation alleviates spinal cord injury-induced neuroinflammation partly by suppressing the Jagged1/Notch pathway. — PubMed · 2020 · Journal Article
- Curcumin protects BV2 cells against lipopolysaccharide-induced injury via adjusting the miR-362-3p/TLR4 axis. — PubMed · 2020 · Journal Article
- Harpagophytum procumbens Extract Ameliorates Allodynia and Modulates Oxidative and Antioxidant Stress Pathways in a Rat Model of Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Nogo receptor decoy promotes recovery and corticospinal growth in non-human primate spinal cord injury. — PubMed · 2020 · Journal Article
- Valproic acid-labeled chitosan nanoparticles promote recovery of neuronal injury after spinal cord injury. — PubMed · 2020 · Journal Article
- Anti-IL-20 antibody improved motor function and reduced glial scar formation after traumatic spinal cord injury in rats. — PubMed · 2020 · Journal Article
- MicroRNA-421-3p-abundant small extracellular vesicles derived from M2 bone marrow-derived macrophages attenuate apoptosis and promote motor function recovery via inhibition of mTOR in spinal cord injury. — PubMed · 2020 · Journal Article
- Loss of SNHG4 Attenuated Spinal Nerve Ligation-Triggered Neuropathic Pain through Sponging miR-423-5p. — PubMed · 2020 · Journal Article
- RNA-seq analysis and compound screening highlight multiple signalling pathways regulating secondary cell death after acute CNS injury in vivo. — PubMed · 2020 · Journal Article
- A novel CX3CR1 inhibitor AZD8797 facilitates early recovery of rat acute spinal cord injury by inhibiting inflammation and apoptosis. — PubMed · 2020 · Journal Article
- Mutually beneficial effects of intensive exercise and GABAergic neural progenitor cell transplants in reducing neuropathic pain and spinal pathology in rats with spinal cord injury. — PubMed · 2020 · Journal Article
- Oral treatment with glycyrrhizin inhibits NLRP3 inflammasome activation and promotes microglial M2 polarization after traumatic spinal cord injury. — PubMed · 2020 · Journal Article
- Why do anti-inflammatory signals of bone marrow-derived stromal cells improve neurodegenerative conditions where anti-inflammatory drugs fail? — PubMed · 2020 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 3 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 851312 · accumulated records across collection walks 48 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 29 · accumulated records across collection walks 3219 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroinflammation" OR "microglia" OR "immune response") - Crossref
spinal cord injury neuroinflammation microglia - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neurogenic Inflammation"[MeSH Terms] OR "Microglia"[MeSH Terms] OR "Neuroimmunomodulation"[MeSH Terms] OR "neuroinflammation"[Title/Abstract] OR "microglia"[Title/Abstract] OR "immune response"[Title/Abstract])