A subject this map covers
Inflammation and immune response
What belongs here
What immune cells do after injury — both as damage and as a necessary part of healing.
What does not belong here, however close it looks
Infection and sepsis are clinical management, a separate subject.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 769 records · 1981–2027
- Indexed as work in animals: 1704 records · 1975–2027
- Indexed as laboratory work: 73 records · 2001–2026
- The source has not said who or what was studied: 639 records · 1998–2026
- No matching published catalogue records are linked above. Human-review status must be checked on the evidence itself.
Published in this map
Catalogue records matching this subject. Publication here does not establish human review, measured results or effectiveness. Open a record to inspect its sources and evidence.
No published catalogue records match this subject yet.
This is a result within this map, not a claim that no research exists. The source records below can help you continue searching.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3185 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Indexed as work in animals
- Repairing and Analgesic Effects of Umbilical Cord Mesenchymal Stem Cell Transplantation in Mice with Spinal Cord Injury. — PubMed · 2020 · Journal Article
- A novel hydrogel-based treatment for complete transection spinal cord injury repair is driven by microglia/macrophages repopulation. — PubMed · 2020 · Journal Article
- Riluzole improves functional recovery after acute spinal cord injury in rats and may be associated with changes in spinal microglia/macrophages polarization. — PubMed · 2020 · Journal Article
- Microglia and macrophages promote corralling, wound compaction and recovery after spinal cord injury via Plexin-B2. — PubMed · 2020 · Journal Article
- Modulating Pro-inflammatory Cytokines, Tissue Damage Magnitude, and Motor Deficit in Spinal Cord Injury with Subventricular Zone-Derived Extracellular Vesicles. — PubMed · 2020 · Journal Article
- Safe range of shortening the middle thoracic spine, an experimental study in canine. — PubMed · 2020 · Journal Article
- Elevated TRPV4 Levels Contribute to Endothelial Damage and Scarring in Experimental Spinal Cord Injury. — PubMed · 2020 · Journal Article
- Astroglial TLR9 antagonism promotes chemotaxis and alternative activation of macrophages via modulation of astrocyte-derived signals: implications for spinal cord injury. — PubMed · 2020 · Journal Article
- Exosome-shuttled miR-216a-5p from hypoxic preconditioned mesenchymal stem cells repair traumatic spinal cord injury by shifting microglial M1/M2 polarization. — PubMed · 2020 · Journal Article
- Isolation and RNA purification of macrophages/microglia from the adult mouse spinal cord. — PubMed · 2020 · Journal Article
- Melatonin exerts neuroprotective effects by attenuating astro- and microgliosis and suppressing inflammatory response following spinal cord injury. — PubMed · 2020 · Journal Article
- MicroRNA-34a suppresses neuronal apoptosis and alleviates microglia inflammation by negatively targeting the Notch pathway in spinal cord injury. — PubMed · 2020 · Journal Article
- Scar Tissue-Targeting Polymer Micelle for Spinal Cord Injury Treatment. — PubMed · 2020 · Journal Article
- Stress Pathway Modulation Is Detrimental or Ineffective for Functional Recovery after Spinal Cord Injury in Mice. — PubMed · 2020 · Journal Article
- Transplantation of M2-Deviated Microglia Promotes Recovery of Motor Function after Spinal Cord Injury in Mice. — PubMed · 2020 · Journal Article
- Alkaline-phosphatase triggered self-assemblies enhances the anti-inflammatory property of methylprednisolone in spinal cord injury. — PubMed · 2020 · Journal Article
- Anti-inflammatory Effect of AZD6244 on Acrolein-Induced Neuroinflammation. — PubMed · 2020 · Journal Article
- Dual regulation of microglia and neurons by Astragaloside IV-mediated mTORC1 suppression promotes functional recovery after acute spinal cord injury. — PubMed · 2020 · Journal Article
- Invasion of microglia/macrophages and granulocytes into the Mauthner axon myelin sheath following spinal cord injury of the adult goldfish, Carassius auratus. — PubMed · 2020 · Journal Article
- MiRNA-411 attenuates inflammatory damage and apoptosis following spinal cord injury. — PubMed · 2020 · Journal Article
- The Effect of Spinal Cord Injury on Beta-Amyloid Plaque Pathology in TgCRND8 Mouse Model of Alzheimer's Disease. — PubMed · 2020 · Journal Article
- Traumatic Injury Reduces Amyloid Plaque Burden in the Transgenic 5xFAD Alzheimer's Mouse Spinal Cord. — PubMed · 2020 · Journal Article
- Lentivirus-mediated downregulation of α-synuclein reduces neuroinflammation and promotes functional recovery in rats with spinal cord injury. — PubMed · 2019 · Journal Article
- Curcumin Alleviates Lipopolysaccharide (LPS)-Activated Neuroinflammation via Modulation of miR-199b-5p/IκB Kinase β (IKKβ)/Nuclear Factor Kappa B (NF-κB) Pathway in Microglia. — PubMed · 2019 · Journal Article
- Insulin-like growth factor-1 enhances neuroprotective effects of neural stem cell exosomes after spinal cord injury via an miR-219a-2-3p/YY1 mechanism. — PubMed · 2019 · Journal Article
- Targeting CARD6 attenuates spinal cord injury (SCI) in mice through inhibiting apoptosis, inflammation and oxidative stress associated ROS production. — PubMed · 2019 · Journal Article
- MIC-1/GDF15 Overexpression Is Associated with Increased Functional Recovery in Traumatic Spinal Cord Injury. — PubMed · 2019 · Journal Article
- CGRP accelerates the pathogenesis of neurological heterotopic ossification following spinal cord injury. — PubMed · 2019 · Journal Article
- CRNDE enhances neuropathic pain via modulating miR-136/IL6R axis in CCI rat models. — PubMed · 2019 · Journal Article
- Dexmedetomidine modulates neuroinflammation and improves outcome via alpha2-adrenergic receptor signaling after rat spinal cord injury. — PubMed · 2019 · Journal Article
- Imaging the dynamic interactions between immune cells and the neurovascular interface in the spinal cord. — PubMed · 2019 · Journal Article
- Intravenous transplantation of olfactory bulb ensheathing cells for a spinal cord hemisection injury rat model. — PubMed · 2019 · Journal Article
- Progranulin deficiency exacerbates spinal cord injury by promoting neuroinflammation and cell apoptosis in mice. — PubMed · 2019 · Journal Article
- Hydrogen-rich Saline Alleviated the Hyperpathia and Microglia Activation via Autophagy Mediated Inflammasome Inactivation in Neuropathic Pain Rats. — PubMed · 2019 · Journal Article
- Ameliorative effects of echinacoside against spinal cord injury via inhibiting NLRP3 inflammasome signaling pathway. — PubMed · 2019 · Journal Article
- Quercetin prevents necroptosis of oligodendrocytes by inhibiting macrophages/microglia polarization to M1 phenotype after spinal cord injury in rats. — PubMed · 2019 · Journal Article
- Roles of extra-cellular signal-regulated protein kinase 5 signaling pathway in the development of spinal cord injury. — PubMed · 2019 · Journal Article
- Inhibition of microRNA-711 limits angiopoietin-1 and Akt changes, tissue damage, and motor dysfunction after contusive spinal cord injury in mice. — PubMed · 2019 · Journal Article
- Berberine enhances survival and axonal regeneration of motoneurons following spinal root avulsion and re-implantation in rats. — PubMed · 2019 · Journal Article
- MiR-223-5p inhibitor suppresses microglia inflammation and promotes Nrg-1 in rats of spinal cord injury. — PubMed · 2019 · Journal Article
- Neuronal activity and microglial activation support corticospinal tract and proprioceptive afferent sprouting in spinal circuits after a corticospinal system lesion. — PubMed · 2019 · Journal Article
- Systemic Inhibition of Soluble Tumor Necrosis Factor with XPro1595 Exacerbates a Post-Spinal Cord Injury Depressive Phenotype in Female Rats. — PubMed · 2019 · Journal Article
- Role of macrophages and activated microglia in neuropathic pain associated with chronic progressive spinal cord compression. — PubMed · 2019 · Journal Article
- Exosomes Derived From Bone Marrow Mesenchymal Stem Cells Inhibit Complement Activation In Rats With Spinal Cord Injury. — PubMed · 2019 · Journal Article
- Removal of the Potassium Chloride Co-Transporter from the Somatodendritic Membrane of Axotomized Motoneurons Is Independent of BDNF/TrkB Signaling But Is Controlled by Neuromuscular Innervation. — PubMed · 2019 · Journal Article
- Elimination of microglia in mouse spinal cord alters the retrograde CNS plasticity observed following peripheral axon injury. — PubMed · 2019 · Journal Article
- MAP‑1B, PACS‑2 and AHCYL1 are regulated by miR‑34A/B/C and miR‑449 in neuroplasticity following traumatic spinal cord injury in rats: Preliminary explorative results from microarray data. — PubMed · 2019 · Journal Article
- MiR-100 suppresses inflammatory activation of microglia and neuronal apoptosis following spinal cord injury via TLR4/NF-κB pathway. — PubMed · 2019 · Journal Article
- Silencing miR-21 induces polarization of astrocytes to the A2 phenotype and improves the formation of synapses by targeting glypican 6 via the signal transducer and activator of transcription-3 pathway after acute ischemic spinal cord injury. — PubMed · 2019 · Journal Article
- Sting is a critical regulator of spinal cord injury by regulating microglial inflammation via interacting with TBK1 in mice. — PubMed · 2019 · Journal Article
- Targeting miR-106-3p facilitates functional recovery via inactivating inflammatory microglia and interfering glial scar component deposition after neural injury. — PubMed · 2019 · Journal Article
- TMEM16F inhibition limits pain-associated behavior and improves motor function by promoting microglia M2 polarization in mice. — PubMed · 2019 · Journal Article
- Neural stem cell small extracellular vesicle-based delivery of 14-3-3t reduces apoptosis and neuroinflammation following traumatic spinal cord injury by enhancing autophagy by targeting Beclin-1. — PubMed · 2019 · Journal Article
- CCL28 promotes locomotor recovery after spinal cord injury via recruiting regulatory T cells. — PubMed · 2019 · Journal Article
- Effects of Sirtuin 1 on microglia in spinal cord injury: involvement of Wnt/β-catenin signaling pathway. — PubMed · 2019 · Journal Article
- Upregulated protein O-GlcNAcylation promoted functional and structural recovery of the contused spinal cord injury in rats by Thiamet-G treatment. — PubMed · 2019 · Journal Article
- ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injury. — PubMed · 2019 · Journal Article
- Chondroitinase improves anatomical and functional outcomes after primate spinal cord injury. — PubMed · 2019 · Journal Article
- Conditional ablation of reactive astrocytes to dissect their roles in spinal cord injury and repair. — PubMed · 2019 · Journal Article
- Endogenous Interleukin-10 Deficiency Exacerbates Vascular Pathology in Traumatic Cervical Spinal Cord Injury. — PubMed · 2019 · Journal Article
Where this was looked for, and when
The latest collection walk and the accumulated shelf have different scopes. A zero applies only to that source query and its date window; older records may remain on the shelf. It does not mean no research exists.
| ClinicalTrials.gov | latest collection walk returned no records | asked on 2026-10-05 Collection window: 2026-09-16 – 2026-10-05 | matched in this collection walk 0 · accumulated records across collection walks 3 · still to fetch in this walk 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 Collection window: all dates before the end date – 2026-09-16 | matched in this collection walk 851312 · accumulated records across collection walks 48 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 Collection window: 2026-09-17 – 2026-10-12 | matched in this collection walk 29 · accumulated records across collection walks 3219 · still to fetch in this walk 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroinflammation" OR "microglia" OR "immune response") - Crossref
spinal cord injury neuroinflammation microglia - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neurogenic Inflammation"[MeSH Terms] OR "Microglia"[MeSH Terms] OR "Neuroimmunomodulation"[MeSH Terms] OR "neuroinflammation"[Title/Abstract] OR "microglia"[Title/Abstract] OR "immune response"[Title/Abstract])