A subject this map covers
Inflammation and immune response
What belongs here
What immune cells do after injury — both as damage and as a necessary part of healing.
What does not belong here, however close it looks
Infection and sepsis are clinical management, a separate subject.
What has been looked at
Counted from what the sources catalogue, not from reading the work. It says how much exists and over what span of years — never what any of it found.
- Registered or indexed as work in people: 769 records · 1981–2027
- Indexed as work in animals: 1704 records · 1975–2027
- Indexed as laboratory work: 73 records · 2001–2026
- The source has not said who or what was studied: 639 records · 1998–2026
- Nobody has yet checked any of this against its original for this map, so none of it is on the checked shelf.
Checked
Records a person has read against the original and published into this map. These carry measurements, evidence states and a place on the ladder.
Nobody has checked a record on this subject yet.
Checking is done by a person, one record at a time, and this subject has not reached the queue yet. The shelf below is what the sources hold in the meantime; it has not been read by anybody.
Found in the scientific sources, not yet checked
Titles and identifiers as the sources publish them. Nobody here has read these papers, and nothing on this shelf is a result, a recommendation or evidence that anything works. Each line opens the original.
3185 records
This grouping is the source's own cataloguing, not a reading of the paper. It says where a record was filed, not what it found.
Registered or indexed as work in people
- Immunometabolism In Brain Aging and Neurodegeneration: Bridging Metabolic Pathways and Immune Responses. — PubMed · 2024 · Journal Article
- Physicochemical Property Effects on Immune Modulating Polymeric Nanoparticles: Potential Applications in Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Unveiling vital biomarkers and immune infiltration profiles in endoplasmic reticulum stress following spinal cord injury. — PubMed · 2024 · Journal Article
- Pharmacological Network Analysis of the Functions and Mechanism of Quercetin From Jisuikang (JSK) in Spinal Cord Injury (SCI). — PubMed · 2024 · Journal Article
- Proteomic study of cerebrospinal fluid in adult tethered cord syndrome: Chemical structure and function of apolipoprotein B. — PubMed · 2024 · Journal Article The source marks this record as retracted.
- The macrophage migration inhibitory factor/CD74 axis in traumatic spinal cord injury: lessons learned from animal and human studies. — PubMed · 2024 · Journal Article
- Neuropathic Pain Induced by Spinal Cord Injury from the Glia Perspective and Its Treatment. — PubMed · 2024 · Journal Article
- Peripheral immune reactions following human traumatic spinal cord injury: the interplay of immune activation and suppression. — PubMed · 2024 · Journal Article
- The Yin and Yang of Microglia-Derived Extracellular Vesicles in CNS Injury and Diseases. — PubMed · 2024 · Journal Article
- Beneficial Effects of Human Schwann Cell-Derived Exosomes in Mitigating Secondary Damage After Penetrating Ballistic-Like Brain Injury. — PubMed · 2024 · Journal Article
- The Two Faces of HDAC3: Neuroinflammation in Disease and Neuroprotection in Recovery. — PubMed · 2024 · Journal Article
- The role of interferon beta in neurological diseases and its potential therapeutic relevance. — PubMed · 2024 · Journal Article
- Unravelling the Road to Recovery: Mechanisms of Wnt Signalling in Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Research Progress on Treating Spinal Cord Injury by Modulating the Phenotype of Microglia. — PubMed · 2024 · Journal Article
- The Effect of Tissue Inhibitor of Metalloproteinases on Scar Formation after Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Modulatory effects of gut microbiota on innate and adaptive immune responses following spinal cord injury. — PubMed · 2024 · Journal Article
- Fisetin Promotes Functional Recovery after Spinal Cord Injury by Inhibiting Microglia/Macrophage M1 Polarization and JAK2/STAT3 Signaling Pathway. — PubMed · 2024 · Journal Article
- Quercetin-loaded Human Umbilical cord Mesenchymal Stem Cell-derived sEVs for Spinal Cord Injury Recovery. — PubMed · 2024 · Journal Article
- Beyond PDE4 inhibition: A comprehensive review on downstream cAMP signaling in the central nervous system. — PubMed · 2024 · Journal Article
- Neutralizing RGMa with Elezanumab Promotes Cerebroprotection and Recovery in Rabbit Middle Cerebral Artery Occlusion. — PubMed · 2024 · Journal Article
- S100A9 Induces Macrophage M2 Polarization and Immunomodulatory Role in the Lesion Site After Spinal Cord Injury in Rats. — PubMed · 2024 · Journal Article
- The regulating effect of curcumin on NF-κB pathway in neurodegenerative diseases: a review of the underlying mechanisms. — PubMed · 2024 · Journal Article
- Human induced pluripotent stem cell/embryonic stem cell-derived pyramidal neuronal precursors show safety and efficacy in a rat spinal cord injury model. — PubMed · 2024 · Journal Article
- Re-analysis of single-cell RNA-seq data reveals the origin and roles of cycling myeloid cells. — PubMed · 2024 · Journal Article
- Amelioration of functional and histopathological consequences after spinal cord injury through phosphodiesterase 4D (PDE4D) inhibition. — PubMed · 2024 · Journal Article
- Zein-Based Triple-Drug Nanoparticles to Promote Anti-Inflammatory Responses for Nerve Regeneration after Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Recombinant fibroblast growth factor 4 ameliorates axonal regeneration and functional recovery in acute spinal cord injury through altering microglia/macrophage phenotype. — PubMed · 2024 · Journal Article
- Immunoregulation of Glia after spinal cord injury: a bibliometric analysis. — PubMed · 2024 · Journal Article
- Oligodendrocyte Progenitors in Glial Scar: A Bet on Remyelination. — PubMed · 2024 · Journal Article
- Commentary: Mesenchymal stem cells in the treatment of spinal cord injury: mechanisms, current advances and future challenges. — PubMed · 2024 · Journal Article
- Disrupted autonomic pathways in spinal cord injury: Implications for the immune regulation. — PubMed · 2024 · Journal Article
- Inflammatory response in traumatic brain and spinal cord injury: The role of XCL1-XCR1 axis and T cells. — PubMed · 2024 · Journal Article
- Targeted Repair of Spinal Cord Injury Based on miRNA-124-3p-Loaded Mesoporous Silica Camouflaged by Stem Cell Membrane Modified with Rabies Virus Glycoprotein. — PubMed · 2024 · Journal Article
- Preconditioning of MSCs for Acute Neurological Conditions: From Cellular to Functional Impact-A Systematic Review. — PubMed · 2024 · Systematic Review
- Immunotherapy of M2 macrophage derived from exosome-based nanoparticles for spinal cord injury. — PubMed · 2024 · Journal Article
- Molars to Medicine: A Focused Review on the Pre-Clinical Investigation and Treatment of Secondary Degeneration following Spinal Cord Injury Using Dental Stem Cells. — PubMed · 2024 · Journal Article
- Advanced Magnetic Resonance Imaging Biomarkers of the Injured Spinal Cord: A Comparative Study of Imaging and Histology in Human Traumatic Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Longitudinal motor system changes from acute to chronic spinal cord injury. — PubMed · 2024 · Journal Article
- Network pharmacology analysis and animal experiment validation of neuroinflammation inhibition by total ginsenoside in treating CSM. — PubMed · 2024 · Journal Article
- α-Gal Nanoparticles in CNS Trauma: II. Immunomodulation Following Spinal Cord Injury (SCI) Improves Functional Outcomes. — PubMed · 2024 · Journal Article
- α-Gal Nanoparticles in CNS Trauma: I. In Vitro Activation of Microglia Towards a Pro-Healing State. — PubMed · 2024 · Journal Article
- NF-κB and JAK/STAT Signaling Pathways as Crucial Regulators of Neuroinflammation and Astrocyte Modulation in Spinal Cord Injury. — PubMed · 2024 · Journal Article
- BM-MSC-Loaded Graphene-Collagen Cryogels Ameliorate Neuroinflammation in a Rat Spinal Cord Injury Model. — PubMed · 2024 · Journal Article
- Exosomes derived from umbilical cord-mesenchymal stem cells inhibit the NF-κB/MAPK signaling pathway and reduce the inflammatory response to promote recovery from spinal cord injury. — PubMed · 2024 · Journal Article
- Non-stem cell-derived exosomes: a novel therapeutics for neurotrauma. — PubMed · 2024 · Journal Article
- BMSCs-derived exosomes inhibit macrophage/microglia pyroptosis by increasing autophagy through the miR-21a-5p/PELI1 axis in spinal cord injury. — PubMed · 2024 · Journal Article
- Decoding the spatiotemporal regulation of transcription factors during human spinal cord development. — PubMed · 2024 · Journal Article
- Exploring the mechanisms of kaempferol in neuroprotection: Implications for neurological disorders. — PubMed · 2024 · Journal Article
- Role of dendritic cells in spinal cord injury. — PubMed · 2024 · Journal Article
- Single-cell RNA sequencing reveals peripheral blood leukocyte responses to spinal cord injury in mice with humanised immune systems. — PubMed · 2024 · Journal Article
- Complanatuside A improves functional recovery after spinal cord injury through inhibiting JNK signaling-mediated microglial activation. — PubMed · 2024 · Journal Article
- Emerging functions and therapeutic targets of IL-38 in central nervous system diseases. — PubMed · 2024 · Journal Article
- Ligand-Screened Cerium-Based MOF Microcapsules Promote Nerve Regeneration via Mitochondrial Energy Supply. — PubMed · 2024 · Journal Article
- METTL3 promotes microglial inflammation via MEF2C in spinal cord injury. — PubMed · 2024 · Journal Article
- Microglial TNFR2 signaling regulates the inflammatory response after CNS injury in a sex-specific fashion. — PubMed · 2024 · Journal Article
- Polyphenols Targeting NF-κB Pathway in Neurological Disorders: What We Know So Far? — PubMed · 2024 · Journal Article
- Improved Efficacy of Delayed Treatment with Human Bone Marrow-Derived Stromal Cells Evaluated in Rats with Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Cytoplasmic Escape of Mitochondrial DNA Mediated by Mfn2 Downregulation Promotes Microglial Activation via cGas-Sting Axis in Spinal Cord Injury. — PubMed · 2024 · Journal Article
- Zeolitic imidazole framework-8 loaded gelatin methacryloyl microneedles: A transdural and controlled-release drug delivery system attenuates neuroinflammation after spinal cord injury. — PubMed · 2024 · Journal Article
- Transcriptome Profiling after Early Spinal Cord Injury in the Axolotl and Its Comparison with Rodent Animal Models through RNA-Seq Data Analysis. — PubMed · 2023 · Journal Article
Where this was looked for, and when
The exact question each source was asked, the day it was asked, and what came back. A zero on this page is only honest if these are on it.
| ClinicalTrials.gov | asked, and it has nothing | asked on 2026-10-05 | the source found 0 · this programme has 3 · still to fetch 0 | aim: every record matching this question |
|---|---|---|---|---|
| Crossref | asked, and it answered | asked on 2026-09-16 | the source found 851312 · this programme has 48 | aim: a sample of the most relevant records. This source ranks a bag of words, so its own total is the size of the corpus that shares some of them, never a set still owed. |
| PubMed | asked, and it answered | asked on 2026-10-12 | the source found 29 · this programme has 3219 · still to fetch 0 | aim: every record matching this question |
The question asked
- ClinicalTrials.gov
("neuroinflammation" OR "microglia" OR "immune response") - Crossref
spinal cord injury neuroinflammation microglia - PubMed
("Spinal Cord Injuries"[MeSH Terms] OR "spinal cord injury"[Title/Abstract] OR "spinal cord injuries"[Title/Abstract] OR "spinal cord trauma"[Title/Abstract]) AND ("Neurogenic Inflammation"[MeSH Terms] OR "Microglia"[MeSH Terms] OR "Neuroimmunomodulation"[MeSH Terms] OR "neuroinflammation"[Title/Abstract] OR "microglia"[Title/Abstract] OR "immune response"[Title/Abstract])